Retinal
Appears on 1 avoid lists
Included in 22 routines
Summary
Works for
- Evens skin tone
- Anti-blemish
- Anti-aging
Irritancy risk
HIGH
WIMJ Team
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Products with Retinal
cocokind
advanced retinol gel 0.5%
Works for:
- Anti-aging
- Evens skin tone
- Anti-blemish
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Irritancy risk:
Key ingredients:
- hydroxypinacolone retinoate
- retinal
- retinol
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Medicube
Deep Reviving Bakuchiol Retinol Serum
Works for:
- Anti-aging
- Evens skin tone
- Anti-oxidation
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Irritancy risk:
Key ingredients:
- niacinamide
- hydroxypinacolone retinoate
- retinyl retinoate
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Paula's choice
PRO Retinaldehyde Treatment
Works for:
- Anti-aging
- Anti-blemish
- Evens skin tone
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Irritancy risk:
Key ingredients:
- retinal
- glycerin
- isopropyl myristate
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K-SECRET
SEOUL 1988 CREAM : RETINAL LIPOSOME 1% + FERMENTED RICE
Works for:
- Anti-aging
- Moisturizing
- Evens skin tone
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Irritancy risk:
Key ingredients:
- niacinamide
- retinal
- adenosine
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Dr Emi Arpa
Absolut A Retinal Serum
Works for:
- Anti-aging
- Moisturizing
- Evens skin tone
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Irritancy risk:
Key ingredients:
- copper tripeptide-1
- retinal
- palmitoyl pentapeptide-4
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Facetheory
Retinal Supreme MultiCream 0.05%
Works for:
- Moisturizing
- Anti-aging
- Evens skin tone
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Irritancy risk:
Key ingredients:
- niacinamide
- hydroxypinacolone retinoate
- acetyl tetrapeptide-9
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Revox
Just retinal
Works for:
- Anti-aging
- Evens skin tone
- Anti-blemish
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Irritancy risk:
Key ingredients:
- Vitamin C
- retinal
- panthenol
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Fraijour
Retin-Collagen 3D Core Cream
Works for:
- Anti-aging
- Moisturizing
- Evens skin tone
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Irritancy risk:
Key ingredients:
- tripeptide-1
- acetyl tetrapeptide-5
- copper tripeptide-1
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Ursa Major
Lunar Bloom Retinal Serum
Works for:
- Anti-aging
- Evens skin tone
- Anti-blemish
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Irritancy risk:
Key ingredients:
- retinal
- caprylic/capric triglyceride
- gardenia jasminoides meristem cell culture
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Miss Alice Cosmetics
Retinal Level Up
Works for:
- Anti-aging
- Moisturizing
- Evens skin tone
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Irritancy risk:
Key ingredients:
- niacinamide
- retinal
- anhydroxylitol
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Questions
Clinical trials review
| Number of participants | Participants | Interventions | Punchline |
|---|---|---|---|
| 40 | 40 healthy Korean female volunteers >30 years old. The exclusion criteria were facial dermatosis, a known allergy to any cosmetic ingredient, and prior use of topical or systemic retinoids or steroids. | Either the RAL 0.1% or RAL 0.05% cream was applied twice daily. The study duration was 12 weeks and included four assessment visits: an inclusion visit in week 0 (baseline), and three further visits at 4, 8, and 12 weeks | The 3-month application improved overall photoaging in both RAL 0.1% (95%) and RAL 0.05% groups (95%). Both RAL 0.1% and RAL 0.05% afforded significant textural improvements (13.7% and 12.6%, respectively), reduced the TEWL (14.5%, 17.9%), and increased hydration (10.2%, 6.0%); however, no statistical differences were observed between two groups. Only RAL 0.1% significantly improved the melanin index (by 6.5%) |
Efficacy and safety of retinaldehyde 0.1% and 0.05% creams used to treat photoaged skin: A randomized double-blind controlled trial
| Number of participants | Participants | Interventions | Punchline |
|---|---|---|---|
| 40 | Women over 35 years of age, with moderate to severe photodamage | Patients applied either retinaldehyde 0.05% on their faces once daily for 1 year, or were left untreated (emollient only, control group). | Compared to the control group, retinaldehyde treatment induced a significant increase in epidermal thickness of the temple, as well as in cutaneous elasticity (p < 0.01). Similarly, retinaldehyde treatment tended to increase dermal thickness and reduce cutaneous stiffness, but no statistical difference could be observed between the two groups. |
Efficacy of topical 0.05% retinaldehyde in skin aging by ultrasound and rheological techniques
| Number of participants | Participants | Interventions | Punchline |
|---|---|---|---|
| 55 | Subjects included were female volunteers (age 35-55 years) with skin phototype I-III according to Fitzpatrick classification with at least 1 deep, long (≥1 cm) wrinkle on the flat part of the crow’s feet area, and the presence of periorbicular fine lines and wrinkles. Facial hygiene regimens had to be kept unchanged and be well tolerated for at least 4 weeks before inclusion | Participants were randomized in 2 treatment groups: (1) Daily application of the antiaging cream for 8 weeks or (2) Three sequential GA peels (20%, 50%, and 70%), 2-3 weeks apart. | : Efficacy of both treatments was similar in reducing crow’s feet wrinkles depth (STm 7.61%, P = .0007 vs 4.34%, P = .0348; P = .3049 intergroup) and volume, crow’s feet and periorbital wrinkle length, and number of fine lines and wrinkles at end of treatments. The efficacy of the cream in refining skin texture was superior to the peels (contrast: 5.61%, P = .0025 vs +3.54, P = .08; P intergroup = .0252). The 8-week treatment with the antiaging cream was well tolerated; adverse events were fewer and of milder intensity than with the peels, (12-fold lower incidence of physical signs). |
Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study