Gluconolactone
Appears on 0 avoid lists
Included in 296 routines
Summary
Works for
- Anti-aging
- Exfoliation
- Moisturizing
- Evens skin tone
- Anti-oxidation
- Anti-blemish
Irritancy risk
MEDIUM
WIMJ Team
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Products with Gluconolactone
SKIN 1004.
centella toning toner
Works for:
- Moisturizing
- Exfoliation
- Evens skin tone
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Irritancy risk:
Key ingredients:
- niacinamide
- gluconolactone
- adenosine
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Nivea
Derma Skin Clear Chemical Exfoliator
Works for:
- Anti-blemish
- Exfoliation
- Anti-aging
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Irritancy risk:
Key ingredients:
- salicylic acid
- niacinamide
- glycolic acid
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Charm Medi
Charmine Rose Professional Medi PHA 2% Lactobionic Acid Tonic
Works for:
- Exfoliation
- Anti-aging
- Anti-oxidation
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Irritancy risk:
Key ingredients:
- lactobionic acid
- gluconolactone
- lactic acid
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Bioup
Renewing Peeling with PHA Acids RENEWAL & ANTI-AGING
Works for:
- Anti-aging
- Exfoliation
- Evens skin tone
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Irritancy risk:
Key ingredients:
- lactobionic acid
- gluconolactone
- urea
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Skincyclopedia
Charcoal 5% AHA + PHA Complex
Works for:
- Exfoliation
- Anti-aging
- Evens skin tone
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Irritancy risk:
Key ingredients:
- niacinamide
- gluconolactone
- glycerin
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Skin Rocks
The Gentle Acid
Works for:
- Exfoliation
- Moisturizing
- Anti-aging
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Irritancy risk:
Key ingredients:
- gluconolactone
- lactic acid
- panthenol
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Bubble Skincare
Water Slide
Works for:
- Moisturizing
- Anti-aging
- Evens skin tone
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Irritancy risk:
Key ingredients:
- niacinamide
- gluconolactone
- Prickly pear seed oil
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Skincare by Dr. V
BODY SMOOTHING EXFOLIATOR
Works for:
- Evens skin tone
- Anti-aging
- Anti-blemish
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Irritancy risk:
Key ingredients:
- retinal
- salicylic acid
- niacinamide
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No7
Glycolic Exfoliating Pads
Works for:
- Anti-aging
- Exfoliation
- Moisturizing
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Irritancy risk:
Key ingredients:
- gluconolactone
- glycolic acid
- panthenol
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Raaie
Yellow Moonbeam Retinal Elixir
Works for:
- Anti-aging
- Evens skin tone
- Anti-blemish
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Irritancy risk:
Key ingredients:
- niacinamide
- retinal
- anhydroxylitol
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Questions
Clinical trials review
Number of participants | Participants | Interventions | Punchline |
---|---|---|---|
150 | 76 male and 74 female patients with mild to moderate acne (older than 12 years, free from intercurrent disease, and not taking systemic antibiotics, corticosteroids, retinoids, anticonvulsants or androgens in the 30 days prior to starting the trial. No topical acne therapy was allowed in the two weeks before the trial. Female patients were not to have commenced or ceased the oral contraceptive pill in the six months before the trial, and males were to be without beards and moustaches.) | The patients were randomized into three treatment groups: benzoyl peroxide 5% (n = 50), gluconolatone 14% (n = 50) and its vehicle (placebo) (n = 50). Gluconolactone group: lotion with 14% aqueous solution of gluconolactone. Placebo: its vehicle ie. base lotion minus the gluconolactone. The benzoyl peroxide: a commercially available 5% benzoyl peroxide water-based lotion. Duration: 12 weeks | 14% Gluconolactone lotion is effective as a topical treatment for acne. Gluconolactone is as effective as benzoyl peroxide in reducing the number of inflamed and total lesions, though slightly less effective in reducing the number of non-inflamed lesions. Clinical assessment and self-report of sideeffects showed that the gluconolactone was far better tolerated by facial skin. |
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
Scientifc sources
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids
- Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Light
- Applications of hydroxy acids: classification, mechanisms, and photoactivity