Potassium Azeloyl Diglycinate
In 208 skincare routines
Summary
Works for
- Anti-inflammatory
- Evens skin tone
- Anti-blemish
- Moisturizing
Irritancy risk
1
LowA derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture
Products with Potassium Azeloyl Diglycinate
ZO Skin HealthClear Renewalniacinamideretinolsalicylic acid +8 actives
Evens skin tone Anti-blemish +4
Price unavailable
Allies of SkinFounder's Essence 56 Ellagic & P.A.D. Light Reflecting Fluidpotassium azeloyl diglycinatepanthenolacetyl glucosamine +17 actives
Moisturizing Evens skin tone +3
Price unavailable
CLEARSTEM SkincareBRIGHTMEUPsalicylic acidniacinamidepotassium azeloyl diglycinate +6 actives
Moisturizing Evens skin tone +4
Essential oilsAlcohol
Price unavailable
111SKINDark Spot Correcting Serumniacinamidepotassium azeloyl diglycinategluconolactone +7 actives
Evens skin tone Exfoliation +4
Fragrance
Price unavailable
The ConstantMulti-Active Complex 12 Modern Actives Face Serumsalicylic acidsalicylic acidniacinamide +17 actives
Moisturizing Anti-blemish +4
Price unavailable
facerealityskincare-B2BSalicylic+ Serumsalicylic acidlactic acidpotassium azeloyl diglycinate
Anti-blemish Exfoliation +3
Alcohol
Price unavailable
Face Reality Skincare ProfessionalClear Synergy Peel 3salicylic acidlactic acidglycolic acid +5 actives
Exfoliation Evens skin tone +4
Alcohol
Price unavailable
Face Reality SkincareDaily Plus SPF 30niacinamidepotassium azeloyl diglycinatepanthenol +9 actives
Moisturizing Anti-blemish +3
Price unavailable
Beauty PieYouthbomb Breakthrough Repair Double Vitamin Creamniacinamidebakuchiolpotassium azeloyl diglycinate +6 actives
Anti-aging Evens skin tone +3
Price unavailable
EveredenBalance Up Clarifying Toner Padsniacinamidegluconolactonepotassium azeloyl diglycinate +7 actives
Exfoliation Anti-aging +4
Price unavailable
Clinical trials review
The mean erythema index in the ancova model showed a statistically significant reduction at the end of treatment in favor of P-3075 in all evaluated facial areas (Fig. 1). A significant decrease in erythema was present from D14 on.
patients of both genders,
aged 18–60 years and suffering from stage I and II rosacea.n=42Patients meeting the inclusion criteria were randomly
allocated to P-3075 cream (containing 5% potassium azeloyl diglycinate (Azeloglicina;
Sinerga S.p.A., Milan, Italy) and 1% HPCH) or placebo, corresponding to
the moisturizing vehicle of the P-3075 cream. Patients were treated twice daily for 28 days (D) with a
2-week follow-up period. The assessments were performed at inclusion (baseline), at D7, D14, D28 (end of
treatment), and D42 (end of follow-up).
Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea
Scientific sources
- Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea
- A Preliminary Clinical Evaluation of a Topical Product for Reducing Slight Rosacea Imperfections
- Azeloyl-Glycine: A new active in skin disequilibrium
- Formulation and evaluation of the cream made from potassium azeloyl diglycinate as an anti-aging
Similar ingredients
Anti-inflammatory
Acetyl Dipeptide-1 Cetyl EsterA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinklesAllantoinHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydratedAvena Sativa Kernel ExtractAn effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties
Evens skin tone
1-Trimethyl-2-Cyclohexenyl-1-Penten-3-OneAcetyl GlucosamineAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skinGlycolic AcidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
Anti-blemish
Salicylic AcidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)NiacinamideIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum productionSodium Ascorbyl PhosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C