Potassium azeloyl diglycinate

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Included in 208 routines

Summary

Works for
  • Anti-inflammatory
  • Evens skin tone
  • Anti-blemish
  • Moisturizing
Irritancy risk
LOW
WIMJ Team

A derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture

Products with Potassium azeloyl diglycinate

Seveki - сыворотка для проблемной кожи с азелаиновой кислотой Seveki сыворотка для проблемной кожи с азелаиновой кислотой
Works for:
  • Exfoliation
  • Anti-oxidation
  • Anti-aging
Irritancy risk:
Key ingredients:
  • azelaic acid
  • retinol
  • salicylic acid
Avoskin - Your Skin Bae Azeclair 10% + Kombucha 3% + Niacinamide 2.5% Serum Avoskin Your Skin Bae Azeclair 10% + Kombucha 3% + Niacinamide 2.5% Serum
Works for:
  • Evens skin tone
  • Anti-blemish
  • Anti-aging
Irritancy risk:
Key ingredients:
  • niacinamide
  • potassium azeloyl diglycinate
  • allantoin
Rhonda Allison - Brightening Pigment Tonic Rhonda Allison Brightening Pigment Tonic
Works for:
  • Evens skin tone
  • Moisturizing
  • Anti-blemish
Irritancy risk:
Key ingredients:
  • lactic acid
  • potassium azeloyl diglycinate
  • aminobutyric acid
Fig. 1 - Even Tone Serum Fig. 1 Even Tone Serum
Works for:
  • Evens skin tone
  • Anti-aging
  • Moisturizing
Irritancy risk:
Key ingredients:
  • niacinamide
  • alpha-arbutin
  • potassium azeloyl diglycinate
Temple skincare - TMPL Hydrating Face Moisturiser Temple skincare TMPL Hydrating Face Moisturiser
Works for:
  • Anti-aging
  • Moisturizing
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • niacinamide
  • potassium azeloyl diglycinate
  • phytosphingosine
LA CABINE - Dark Spots Serum LA CABINE Dark Spots Serum
Works for:
  • Anti-blemish
  • Evens skin tone
  • Anti-aging
Irritancy risk:
Key ingredients:
  • niacinamide
  • potassium azeloyl diglycinate
  • 3-o-ethyl ascorbic acid
Cipher Skincare - 88MPH Cipher Skincare 88MPH
Works for:
  • Anti-blemish
  • Anti-aging
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • salicylic acid
  • madecassoside
  • retinal
Skincare by Dr. V - BODY SMOOTHING EXFOLIATOR Skincare by Dr. V BODY SMOOTHING EXFOLIATOR
Works for:
  • Evens skin tone
  • Anti-aging
  • Anti-blemish
Irritancy risk:
Key ingredients:
  • retinal
  • salicylic acid
  • niacinamide
Transparent Labs - PIH SUN SPOT FADING TREATMENT Transparent Labs PIH SUN SPOT FADING TREATMENT
Works for:
  • Evens skin tone
  • Anti-blemish
  • Moisturizing
Irritancy risk:
Key ingredients:
  • salicylic acid
  • niacinamide
  • potassium azeloyl diglycinate
Acnemy - ZITCLEAN PURIFYING CLEANSING GEL Acnemy ZITCLEAN PURIFYING CLEANSING GEL
Works for:
  • Anti-blemish
  • Cleansing
  • Exfoliation
Irritancy risk:
Key ingredients:
  • salicylic acid
  • potassium azeloyl diglycinate
  • ceramide np
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Questions

Clinical trials review

Number of participants Participants Interventions Punchline
42 patients of both genders, aged 18–60 years and suffering from stage I and II rosacea. Patients meeting the inclusion criteria were randomly allocated to P-3075 cream (containing 5% potassium azeloyl diglycinate (Azeloglicina; Sinerga S.p.A., Milan, Italy) and 1% HPCH) or placebo, corresponding to the moisturizing vehicle of the P-3075 cream. Patients were treated twice daily for 28 days (D) with a 2-week follow-up period. The assessments were performed at inclusion (baseline), at D7, D14, D28 (end of treatment), and D42 (end of follow-up). The mean erythema index in the ancova model showed a statistically significant reduction at the end of treatment in favor of P-3075 in all evaluated facial areas (Fig. 1). A significant decrease in erythema was present from D14 on.

Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea

Scientifc sources

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