Dupes & alternatives for SkinMedica-Age Defense Retinol Complex .25

Age Defense Retinol Complex .25
SkinMedica

Age Defense Retinol Complex .25

Medium irritancy Score: 100/100
21 alternatives found · Best match: 76% (High)
In The Deep Vitamin A Nourishing Retinol Serum
$19.49
Medium irritancy

Why it matches

RETINOLNIACINAMIDECERAMIDE 3 +2 more

Key differences

PANTHENOLSACCHARIDE ISOMERATESODIUM HYALURONATE +4 more
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Similarity breakdown
Overall formula76%
Hero ingredients100%
Active ingredients58%
All ingredients35%
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Intensive Age Refining Treatment 0.5 Percent Pure Retinol Night
$101.00
Medium irritancy

Why it matches

RETINOLNIACINAMIDESQUALENE +4 more

Key differences

MYRISTOYL NONAPEPTIDE-3PANTHENOLISOSORBIDE DICAPRYLATE +6 more
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Retinol Cica Moisture Recovery Serum
$34.00
Medium irritancy

Why it matches

NIACINAMIDERETINOLGLYCERIN +3 more

Key differences

ACETYL TETRAPEPTIDE-11ADENOSINEMADECASSIC ACID +11 more
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2.5% Retinol Bakuchiol Serum
72%
High match
$31.50
Medium irritancy

Why it matches

NIACINAMIDERETINOLGLYCERIN +2 more

Key differences

BAKUCHIOLLIMNANTHES ALBA SEED OILPOLYGLUTAMIC ACID +2 more
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Similarity breakdown
Overall formula72%
Hero ingredients100%
Active ingredients58%
All ingredients18%
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Vitamin C Super Serum Plus
70%
High match
$25.00
High irritancy

Why it matches

NIACINAMIDERETINOLTOCOPHEROL +1 more

Key differences

ASCORBIC ACIDSALICYLIC ACIDCOPERNICIA CERIFERA WAX +4 more
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Similarity breakdown
Overall formula70%
Hero ingredients100%
Active ingredients35%
All ingredients29%
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Vitamin Amen
Dr Naomi Skin
Vitamin Amen
67%
Medium match
$139.00
High irritancy

Why it matches

RETINOLNIACINAMIDEPALMITOYL TRIPEPTIDE-8 +3 more

Key differences

HYDROXYPINACOLONE RETINOATEBAKUCHIOLACETYL GLUCOSAMINE +9 more
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Vital Vita 12 Firming Ampoule
64%
Medium match
$14.00
High irritancy

Why it matches

NIACINAMIDERETINOLGLYCERIN +3 more

Key differences

OLIGOPEPTIDE-1RETINYL PALMITATEADENOSINE +22 more
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Ferulic Acid + Retinol Brightening Solution
64%
Medium match
$87.00
High irritancy

Why it matches

NIACINAMIDERETINOLTOCOPHEROL +2 more

Key differences

LACTIC ACIDADENOSINEGLYCOLIC ACID +10 more
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Retinol Rapid Repair & Dark Spot Treatment
63%
Medium match
$25.99
High irritancy

Why it matches

NIACINAMIDERETINOLCERAMIDE 3 +3 more

Key differences

AZELAIC ACIDALPHA-ARBUTINRETINYL PALMITATE +6 more
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Revitalize Retinol Serum
63%
Medium match
$41.58
High irritancy

Why it matches

NIACINAMIDERETINOLGLYCERIN +2 more

Key differences

FERRIC HEXAPEPTIDE-35FERULIC ACIDTETRAHEXYLDECYL ASCORBATE +16 more
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Clearing Night Serum With Honestly Pure Retinol
High irritancy

Why it matches

NIACINAMIDERETINOLGLYCERIN +3 more

Key differences

SALICYLIC ACIDGLUCONOLACTONECORALLINA OFFICINALIS EXTRACT +9 more
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About Similarity Scores

Our similarity score compares product formulas based on shared active ingredients, hero ingredients, and overall formula composition. A higher score means a more similar formula.

70%+ - High match
40-69% - Medium match
<40% - Low match

Note: Similarity is based on WIMJ's formula analysis (actives + overall formula similarity). Ingredient concentrations are estimated; products aren't lab-tested. A similar formula doesn't guarantee the same texture or feel.