PRODUCT REVIEW
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SkinMedica Age Defense Retinol Complex .25
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What can the product work for?
Anti-aging
What does the product description say?
Age Defense Retinol Complex .
niacinamide
2.3% -
2.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
retinol
1.5% -
1.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
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Evens skin tone
What does the product description say?
25 is formulated to renew the skin's tone and texture without irritating the skin.
retinol
1.5% -
1.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
niacinamide
2.3% -
2.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
What does the product description say?
an antioxidant complex, enhancing skin texture and minimizing irritationKey Benefits.
ceramide 3
0.55% -
0.8%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
squalene
0.5% -
0.7%
Irritation risk: Comedogenicity: Medium
Concentration: Effectiveness: HIGH
An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast
dextran
0.15% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps attract water to the most upper layer of the skin. Derived from sugar
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Anti-blemish
retinol
1.5% -
1.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
niacinamide
2.3% -
2.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Exfoliation
retinol
1.5% -
1.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Anti-oxidation
retinol
1.5% -
1.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
tocotrienols
0.55% -
0.85%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms
squalene
0.5% -
0.7%
Irritation risk: Comedogenicity: Medium
Concentration: Effectiveness:
MEDIUM
An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast
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Honesty check
How honest is this product?
Promise | Can it deliver? |
---|---|
Anti-aging | |
Moisturizing | |
Evens skin tone |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 3
Potential irritants
retinol
1.5% -
1.8%
Irritation risk:
Works for:
Anti-blemish,
Evens skin tone,
Anti-aging,
Anti-oxidation,
Exfoliation,
Mattifying
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
cetyl ethylhexanoate
5.8% -
7.1%
Irritation risk:
Works for:
Moisturizing
An emollient that helps soften the skin and creates a thicker product texture
Show more
Comodogenic ingredients
glycine soja oil
4.4% -
5.4%
Irritation risk: Comedogenicity: Medium
Works for:
Moisturizing
A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.
squalene
0.5% -
0.7%
Irritation risk: Comedogenicity: Medium
Works for:
Moisturizing,
Anti-oxidation
An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast
Show more
User reviews (0)
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WIMJ similarity score |
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Key ingredients |
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Irritancy | IRRITANCY
MEDIUM
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HIGH
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MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
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MEDIUM
| IRRITANCY
MEDIUM
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HIGH
| IRRITANCY
MEDIUM
| IRRITANCY
MEDIUM
| IRRITANCY
LOW
| IRRITANCY
MEDIUM
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All ingredients |
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
2.3% -
2.9%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Moisturizing,
Anti-aging,
Reduces irritation,
Anti-inflammatory,
Antibacterial,
Reduces redness
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
retinol
1.5% -
1.8%
Irritation risk:
Works for:
Anti-blemish,
Evens skin tone,
Anti-aging,
Anti-oxidation,
Exfoliation,
Mattifying
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Show more
Potential irritants
retinol
1.5% -
1.8%
Irritation risk:
Works for:
Anti-blemish,
Evens skin tone,
Anti-aging,
Anti-oxidation,
Exfoliation,
Mattifying
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
cetyl ethylhexanoate
5.8% -
7.1%
Irritation risk:
Works for:
Moisturizing
An emollient that helps soften the skin and creates a thicker product texture
Show more
Comodogenic ingredients
glycine soja oil
4.4% -
5.4%
Irritation risk: Comedogenicity: Medium
Works for:
Moisturizing
A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.
squalene
0.5% -
0.7%
Irritation risk: Comedogenicity: Medium
Works for:
Moisturizing,
Anti-oxidation
An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast
Show more
All ingredients
cetyl ethylhexanoate
5.8% -
7.1%
Irritation risk:
Works for:
Moisturizing
An emollient that helps soften the skin and creates a thicker product texture
glycine soja oil
4.4% -
5.4%
Irritation risk: Comedogenicity: Medium
Works for:
Moisturizing
A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.
Show more
Ingredient list view
Water, Cetyl ethylhexanoate, Glycine soja oil, Caprylic/capric triglyceride, Niacinamide, Polyacrylate-13, Squalane, Retinol, Palmitoyl tripeptide-8, Dunaliella salina extract, Magnolia grandiflora bark extract, Tocopherol, Tocotrienols, Ceramide 3, Bisabolol, Phytosterols, Squalene, Tocopheryl acetate, Oryza sativa bran cera, Glycerin, Polysorbate 20, Butylene glycol, Cetyl palmitate, Laureth-23, Trideceth-6 phosphate, Sodium hydroxide, Dicaprylyl ether, Lauryl alcohol, Polyisobutene, Dextran, Potassium sorbate, Disodium edta, Phenoxyethanol, Ethylhexylglycerin
Sources
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Dunaliella salina alga extract inhibits the production of interleukin-6, nitric oxide, and reactive oxygen species by regulating nuclear factor-κB/Janus kinase/signal transducer and activator of transcription in virus-infected RAW264.7 cells
- Biochemical composition and bioactivity screening of various extracts from Dunaliella salina, a green microalga
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
- Tocotrienol‐rich fraction attenuates UV‐induced inflammaging: A bench to bedside study
- Tocotrienols: Vitamin E beyond tocopherols
- Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)
- Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeutics
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Squalene and its potential clinical uses
- Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology
- Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxides
- Glycerol and the skin: holistic approach to its origin and functions