Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
- Anti-oxidation
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 4
Key actives
Product Summary
"JuneCell - Rejuvenation Enriched Eye Cream" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. JuneCell - Rejuvenation Enriched Eye Cream ticks this box. Alanine, algae extract, aspartic acid, biosaccharide gum-1 and glutamic acid in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide 2, ceramide 3, ceramide np, palmitoyl tetrapeptide-7 and phytosphingosine) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- We love that this moisturizer contains a good concentration of niacinamide 1.80% - 2.20%. Niacinamide is a perfect active in a moistruizer because it helps calm down inflamation in skin and support the skin barrier. More than that, it is helpful for most common skin concerns: it helps regulat oil production, help reduce acne and clogged pores, improve skin tone and prevent pigmentation marks. It also helps fight photodamage.
- This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.15% - 0.30%) it cannot have a noticeable benefit for the skin.
- This moisturizer includes a form of Retinoids (vitamin A) - retinyl palmitate 0.15% - 0.25%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
- As a plus, this moisturizer also contains Ceramides (phytosphingosine 0.20% - 0.35%, ceramide np 0.15% - 0.30%, ceramide 3 0.15% - 0.30% and ceramide 2 0.15% - 0.30%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- We like that this moisturizer contains peptides (palmitoyl tripeptide-5 0.15% - 0.25%, palmitoyl tetrapeptide-7 0.20% - 0.40%, palmitoyl pentapeptide-4 0.15% - 0.25%, copper tripeptide-1 0.15% - 0.30% and palmitoyl oligopeptide 0.25% - 0.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.15% - 0.25%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Irritation risk
This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-aging
What does the product description say?
The Omega 3 fatty acids in this formulation play an essential role as they work to to create smoother, younger-looking skin, making this eye cream ideal for people who want to target fine lines and wrinkles around the eye area.
Source: Face the future
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: aspartic acid, copper tripeptide-1, folic acid, palmitoyl oligopeptide, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, resveratrol, serine, threonine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
Anti-oxidation
This product contains antioxidants (resveratrol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - chrysin, tocopheryl linoleate also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing
Plant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating
Might help neutralize free radicals in skin
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An antioxidant that might help neutralize free radicals in skin
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking
Bean seed extract. It might have some anti-oxidant properties
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Evens skin tone
What does the product description say?
Niacinamide helps to even skin tone and reduce the appearance of pigmentation by inhibiting melanin from surfacing on the skin.
Source: Face the future
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide, tranexamic acid
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine, chrysin, glycyrrhiza glabra root extract, paeonia lactiflora root extract, resveratrol.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
Moisturizing
What does the product description say?
Rejuvenation Enriched Eye Cream
Source: From product name
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
alanine, algae extract.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 2, ceramide 3, ceramide np, copper tripeptide-1, niacinamide, palmitoyl oligopeptide, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, phytosphingosine
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
Helps soften the upper layer of the skin
A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing
Lipids that work as an emollient and can be helpful in repairing skin barrier function
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An emollient that is naturally found in skin
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
An amino-acid that helps attract water to the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
An emollient that helps soften the skin
A salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function
An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
Helps to attract water to the upper layer of the skin. Can add sweet taste to lip products
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
Used to preserve products, dissolve other ingredients and create a nice product texture
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps oil and water mix together and works as an emollient
Helps to soften the upper layer of the skin and create a nice product texture
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
Helps preserve products and creates a nice product texture
An emollient that helps create a nice silky finish on the skin
Used to create a nice product texture
An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 JuneCell Rejuvenation Enriched Eye Cream | Current | - | |
NEOGEN X SUR.MEDIC V.Biome Advanced Eye Cream | 79% | $25.16 | |
AHC Eye Cream For Face | 78% | $19.36 | |
 DEWYCEL Eye Plus Cream | 78% | $23.80 | |
 MEDI-PEEL Derma Maison Eye Cream JUMBO | 76% | $105.80 | |
 SKIN627 CERAMIDE with PANTHENOL Intense Eye Cream | 76% | $6.63 |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An emollient that is naturally found in skin
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin
Helps soften the upper layer of the skin
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
An emollient that helps soften the skin
An amino-acid that helps attract water to the upper layer of the skin
A salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function
An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function
Lipids that work as an emollient and can be helpful in repairing skin barrier function
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Potential irritants
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
Used to help oil and water mix together. Can be irritating
Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
An aromatic blend of unspecified and possibly irritating ingredients
Plant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating
Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
A fragrance. Can trigger allergic reactions and be irritating
Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating
A fragrance. Can be irritating
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking
Helps soften the upper layer of the skin and improve the product texture. It can be comedogenic
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
Helps preserve products and creates a nice product texture
Used to preserve products, dissolve other ingredients and create a nice product texture
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Helps create a thicker product consistency. Might be irritating
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
Lipids that work as an emollient and can be helpful in repairing skin barrier function
Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
Comedogenic ingredients
Helps soften the upper layer of the skin and improve the product texture. It can be comedogenic
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
Used to stabilize product formulations and create a nice product texture
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
A preservative. It helps prevent bacterial growth in cosmetic products
Used to help oil and water mix together. Can be irritating
Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
An aromatic blend of unspecified and possibly irritating ingredients
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Dissolves other ingredients. It does not have additional skin benefits compared to plain water
Helps the function of sunscreen and pigment ingredients in the formulation
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps to attract water to the upper layer of the skin. Can add sweet taste to lip products
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products
A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing
A relative of vitamin E (Tocopherol). It can have an anti-oxidant effect in skin and/or to stabilize the product fromulation. It could be irritating but most of the reported allergy and irritation cases appeared in one geographic location (Switzerland) in 1992, and might be due to the quality issues in manufacturing of a particular batch of the ingredient
Plant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals
A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but the research on its effectiveness in skin is lacking
An emollient that helps create a nice silky finish on the skin
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
Helps soften the upper layer of the skin and improve the product texture. It can be comedogenic
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures
Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Helps preserve products and creates a nice product texture
Helps to soften the upper layer of the skin and create a nice product texture
Used to preserve products, dissolve other ingredients and create a nice product texture
Helps to attract water to the upper layer of the skin and can help restore the skin barrier function
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
Used to create a thicker product consistency and stabilize formulations
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles
Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect
Helps create a thicker product consistency. Might be irritating
Helps adjust the product pH and stabilize the formulation
An amino-acid that helps attract water to the upper layer of the skin
A salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function
An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function
An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
Lipids that work as an emollient and can be helpful in repairing skin barrier function
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent
An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
Bean seed extract. It might have some anti-oxidant properties
A fragrance. Can trigger allergic reactions and be irritating
Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating
A fragrance. Can be irritating
Ingredient list view
Water, Glycerin, Caprylic/capric triglyceride, Isohexadecane, Butylene glycol, Niacinamide, Bifida ferment lysate, Stearic acid, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Steareth-14, Propylene glycol, Cetyl alcohol, Dimethicone/vinyl dimethicone crosspolymer, Hexanediol, Tranexamic acid, Phenoxyethanol, Methylpropanediol, Sorbitan sesquioleate, Alcohol, Dimethicone, Polysorbate 60, Steareth-21, Parfum, Tromethamine, Hydrogenated lecithin, Proline, Dioscorea japonica root extract, Sodium hyaluronate, Inositol, Ethylhexylglycerin, Sea water, Glycosyl trehalose, C12-14 pareth-7, Hydrogen dimethicone, Raffinose, Adenosine, Hydrogenated starch hydrolysate, Glyceryl polymethacrylate, Lecithin, Carbomer, Piper methysticum leaf/root/stem extract, Xanthan gum, Olea europaea fruit oil, Ascorbyl glucoside, Zinc pca, Tocopheryl linoleate, Arctium lappa root extract, Phellinus linteus extract, Portulaca oleracea extract, Soluble collagen, Panthenol, Steareth-20, Palmitoyl tripeptide-5, Aloe barbadensis leaf juice, Cnidium officinale root extract, Glycyrrhiza glabra root extract, Paeonia lactiflora root extract, Polyquaternium-51, Polysorbate 20, Propanediol, Pueraria thunbergiana root extract, Cholesterol, Hydrogenated phosphatidylcholine, Isostearyl isostearate, Ceramide 3, Disodium edta, Sodium chloride, Folic acid, Triethylhexanoin, Acetic acid, Inulin lauryl carbamate, Sodium dna, Glucose, Lactic acid, Sodium bicarbonate, Ceramide np, Caprylyl glycol, Hydrogenated polydecene, Pentylene glycol, Glycine, Algae extract, Biosaccharide gum-1, Cetearyl alcohol, Phospholipids, Chlorhexidine digluconate, N-hydroxysuccinimide, Glutamine, Glycine soja sterols, Peg-40 castor oil, Potassium sorbate, Phytosphingosine, Palmitoyl pentapeptide-4, Ceramide 2, Potassium cetyl phosphate, Resveratrol, Potassium chloride, Alanine, Serine, Cystine, Caviar extract, Cetyl hydroxyethylcellulose, Arginine hcl, Asparagine, Aspartic acid, Biotin, Calcium chloride, Cysteine hcl, Disodium phosphate, Ferric citrate, Glutamic acid, Histidine hcl, Isoleucine, Unknown, Linoleic acid, Lysine hcl, Magnesium chloride, Magnesium sulfate, Methionine, Oleic acid, Phenylalanine, Phytosterols, Pyridoxine hcl, Riboflavin, Sodium phosphate, Sodium pyruvate, Squalane, Thiamine hcl, Threonine, Tryptophan, Tyrosine, Valine, Zinc sulfate, Rutin, Palmitoyl oligopeptide, Chrysin, Ascorbic acid, Bioflavonoids, Butyrospermum parkii butter, Hesperidin, Hydrolyzed pea protein, Retinyl palmitate, Tocopherol, Palmitoyl tetrapeptide-7, Copper tripeptide-1, Phaseolus lunatus seed extract, Acetyl tripeptide-1, Butylphenyl methylpropional, Benzyl benzoate, Benzyl salicylate, Hydroxyisohexyl 3-cyclohexene carboxaldehyde
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Bifidobacterium longumlysate, a new ingredient forreactive skin
- Use of Probiotics for Dermal Applications
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
- Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin
- The amelioration effect of tranexamic acid in wrinkles induced by skin dryness
- Efficacy and possible mechanisms of topical tranexamic acid in melasma
- Sorbitan sesquioleate, a common emulsifier in topical corticosteroids, is an important contact allergen
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety Assessment of Tromethamine as Used in Cosmetics
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Safety assessment of hydrogenated starch hydrolysates
- Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oil
- The Roles of Vitamin C in Skin Health
- Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
- Zinc L-pyrrolidone carboxylate inhibits the UVA-induced production of matrix metalloproteinase-1 by in vitro cultured skin fibroblasts, whereas it enhances their collagen synthesis
- Zinc Therapy in Dermatology: A Review
- An Epidemic Outbreak of Papular and Follicular Contact Dermatitis to Tocopheryl Linoleate in Cosmetics. Swiss Contact Dermatitis Research Group
- Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmetics
- Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – part 1: Achillea millefolium–Curcuma longa
- Portulaca oleracea (purslane)
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- The skin-depigmenting potential of Paeonia lactiflora root extract and paeoniflorin: in vitro evaluation using reconstructed pigmented human epidermis
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Folic acid and creatine improve the firmness of human skin in vivo
- Amended Safety Assessment of Triglycerides as Used in Cosmetics
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Epidermal and dermal effects of topical lactic acid
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systems
- Safety Assessment of Polyene Group as Used in Cosmetics
- Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiency
- Functional glycine receptor in cultured human keratinocytes
- Skin permeation and antioxidant efficacy of topically applied resveratrol
- Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
- Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
- Resveratrol as a Multifunctional Topical Hypopigmenting Agent
- Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation
- Resveratrol: A Unique Antioxidant Offering a Multi-Mechanistic Approach for Treating Aging Skin
- Combination of amino acids reduces pigmentation in B16F0 melanoma cells
- Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin
- Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proof
- In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmness
- Safety Assessment of α-Amino Acids as Used in Cosmetics
- Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseases
- Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trial
- The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in Barrier Function
- Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones.
- Safety Assessment of Magnesium Sulfate as Used in Cosmetics
- Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
- https://www.sciencedirect.com/science/article/pii/0168365995000887
- Safety Assessment of Zinc Salts as Used in Cosmetics
- Anti-photoageing and anti-melanogenesis activities of chrysin
- Chrysin Protects Epidermal Keratinocytes from UVA- and UVB-Induced Damage
- Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activity
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds