Filorga

Filorga Hydra-Filler

Name: Filorga - Hydra-Filler
Brand: Filorga

Efficacy87/100IrritancyHigh

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Works for

2 of 2 advertised claims delivered

Anti-aging

14 ingredients credited for this claim

Strong support

What the product description says

“Replenish dull and dry complexions with the Hydra-Filler Cream from Filorga ; a rich, anti-ageing moisturiser that instantly replenishes and hydrates skin.”

Source: Lookfantastic

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: aspartic acid, folic acid, retinyl acetate, serine, threonine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.4%

Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.15–0.3%

Retinyl acetateKey activeEffect: Medium~0.2–0.4%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.2–0.4%

Aminobutyric acidEffect: LowHas been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing~0.25–0.4%

HydroxyprolineEffect: LowIs helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking~0.2–0.4%

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.3–0.55%

NiacinamideUnder-dosedEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.2–0.4%

Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.2–0.4%

GluconolactoneUnder-dosedEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.2–0.4%

NiacinUnder-dosedEffect: MediumA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.2–0.4%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%

Moisturizing

37 ingredients credited for this claim

Good support

What the product description says

“Hydra-Filler”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, aminobutyric acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, pentaerythrityl tetracaprylate/tetracaprate.

HistidineKey active· HumectantEffect: High~0.2–0.4%

InositolKey active· HumectantEffect: High~0.2–0.4%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.65–0.95%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%

TyrosineKey activeEffect: High~0.2–0.4%

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.2–0.4%

Aminobutyric acidKey active· HumectantEffect: HighHas been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing~0.25–0.4%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.2–0.35%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.2–0.4%

Biosaccharide gum-1Key active· HumectantEffect: HighHelps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin~0.25–0.45%

Calcium pantothenateKey activeEffect: HighHelps support skin barrier function improving skin hydration and reducing sensitivity~0.15–0.3%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.2–0.4%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.25–0.4%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.25–0.45%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.4–3%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.2–0.4%

HydroxyprolineKey activeEffect: HighIs helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking~0.2–0.4%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.2–0.4%

Lysine hclKey activeEffect: High~0.2–0.4%

OrnithineKey activeEffect: HighAn amino-acid. Helps attract water to the upper layer of the skin~0.2–0.4%

Pentaerythrityl tetracaprylate/tetracaprateKey active· Emollient, OcclusiveEffect: HighAn emollient that helps soften the skin~1.8–2.1%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.4%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~3.9–4.7%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~4.8–5.9%

ProlineKey activeEffect: Medium~0.25–0.45%

Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~0.3–0.55%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.2–0.4%

Isodecyl neopentanoate· Emollient, OcclusiveEffect: LowAn emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.~3.3–4%

Coenzyme aEffect: LowHelps soften the upper layer of the skin and dissolve other ingredients in a product~0.2–0.4%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.15–0.3%

Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.25–0.5%

Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.45–0.7%

NiacinUnder-dosedEffect: HighA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.2–0.4%

Anti-oxidation

Not advertised by the brand · 8 ingredients credited for this claim

Strong support

This product contains antioxidants (glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - pyridoxine also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

PyridoxineKey activeEffect: MediumMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating~0.2–0.35%

TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.25–0.45%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.2–0.4%

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.3–0.55%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%

GluconolactoneUnder-dosedEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.2–0.4%

Evens skin tone

Not advertised by the brand · 7 ingredients credited for this claim

Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.2–0.4%

NiacinUnder-dosedEffect: MediumA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.2–0.4%

Can it cause trouble?

Irritancy

4 strong irritants: Parfum, Sodium anisate + 2 more — patch-test recommended

High risk

We flagged 23 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.45–0.7%est.

Isopropyl alcoholA drying alcohol. Can increase skin's sensitivity and cause dryness and irritationHigh~0.2–0.35%est.

Sodium anisateUsed as a fragranceHigh~0.2–0.4%est.

MethylisothiazolinoneA preservative. Is a frequent allergenHigh~0.00075–0.0015%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.2–0.4%est.

Retinyl acetate—High~0.2–0.4%est.

NiacinA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effectHigh~0.2–0.4%est.

PyridoxineMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritatingHigh~0.2–0.35%est.

Steareth-21Helps oil and water mix togetherMedium~0.6–0.9%est.

Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.5–0.8%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.45–0.7%est.

ChlorphenesinA preservativeMedium~0.16–0.32%est.

Glyceryl linoleateHelps oil and water mix togetherMedium~0.4–0.6%est.

Sorbitan oleateHelps oil and water mix togetherMedium~0.3–0.55%est.

Sorbitan laurateHelps water and oil mix togetherMedium~0.25–0.45%est.

Potassium hydroxideUsed to adjust the pH level of productsMedium~0.25–0.45%est.

Sodium levulinateA preservativeMedium~0.2–0.4%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.

Potassium sorbateA preservativeMedium~0.25–0.4%est.

Calcium chlorideHelps create a thicker product consistency. Might be irritatingMedium~0.2–0.4%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.25–0.45%est.

TaurineCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectivenessMedium~0.25–0.45%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.2–0.4%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~4.8–5.9%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~3.9–4.7%est.

Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.5–0.8%est.

Sorbitan oleateHelps oil and water mix together2/5~0.3–0.55%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Ethylhexyl palmitate~4.8–5.9%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

Cetearyl alcohol~3.9–4.7%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Isodecyl neopentanoate~3.3–4%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin. It also forms a protective on its surface to reduce water loss.

More about Isodecyl neopentanoate

Glycerin~2.4–3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Synthetic wax~1.9–2.4%

Formula

Irritation risk: Low

Used to stabilize product formulations and thicken product consistency

More about Synthetic wax

Pentaerythrityl tetracaprylate/tetracaprate~1.8–2.1%

Key active

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin

More about Pentaerythrityl tetracaprylate/tetracaprate

Dipalmitoylethyl hydroxyethylmonium methosulfate~1.4–1.7%

Formula

Irritation risk: Low

More about Dipalmitoylethyl hydroxyethylmonium methosulfate

Polyquaternium-37~1.2–1.5%

Formula

Irritation risk: Low

Helps soften the upper layer of the skin and create a nice product finish

More about Polyquaternium-37

Polymethyl methacrylate~0.95–1.2%

Formula

Irritation risk: Low

Is used to enhance product texture and can help to optically mask skin imperfections

More about Polymethyl methacrylate

Sodium hyaluronate~0.65–0.95%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Steareth-21~0.6–0.9%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Steareth-21

Parfum~0.45–0.7%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Ceteareth-20~0.5–0.8%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20

Sucrose palmitate~0.45–0.65%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sucrose palmitate

Caprylic/capric triglyceride~0.45–0.7%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Chlorphenesin~0.16–0.32%

Irritant · medium

Irritation risk: Medium

A preservative

More about Chlorphenesin

Glyceryl linoleate~0.4–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Glyceryl linoleate

Sorbitan oleate~0.3–0.55%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan oleate

Prunus amygdalus dulcis oil~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil

Biosaccharide gum-1~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin

More about Biosaccharide gum-1

Sorbitan laurate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Sorbitan laurate

Isopropyl alcohol~0.2–0.35%

Irritant · high

Irritation risk: High

A drying alcohol. Can increase skin's sensitivity and cause dryness and irritation

More about Isopropyl alcohol

Potassium hydroxide~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Used to adjust the pH level of products

More about Potassium hydroxide

Glyceryl caprylate~0.25–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate

Sodium anisate~0.2–0.4%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Sodium anisate

Sodium levulinate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Sodium levulinate

Salicornia herbacea extract~0.2–0.4%

Formula

Irritation risk: Low

More about Salicornia herbacea extract

Phenoxyethanol~0.25–0.4%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Methylisothiazolinone~0.00075–0.0015%

Irritant · high

Irritation risk: High

A preservative. Is a frequent allergen

More about Methylisothiazolinone

Citric acid~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Potassium sorbate~0.25–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Myristyl malate phosphonic acid~0.2–0.4%

Formula

Irritation risk: Low

More about Myristyl malate phosphonic acid

Tocopherol~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingMoisturizingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Sodium chloride~0.25–0.45%

Formula

Irritation risk: Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride

Glucose~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Potassium chloride~0.25–0.4%

Formula

Irritation risk: Low

More about Potassium chloride

Calcium chloride~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps create a thicker product consistency. Might be irritating

More about Calcium chloride

Magnesium sulfate~0.25–0.45%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Magnesium sulfate

Glutamine~0.2–0.4%

Formula

Irritation risk: Low

More about Glutamine

Sodium phosphate~0.2–0.4%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Sodium phosphate

Sodium acetate~0.2–0.4%

Formula

Irritation risk: Low

More about Sodium acetate

Ascorbic acid~0.2–0.4%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-oxidationEvens skin toneAnti-aging

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Lysine hcl~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Lysine hcl

Arginine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Alanine~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Histidine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Histidine

Valine~0.2–0.4%

Formula

Irritation risk: Low

More about Valine

Leucine~0.2–0.4%

Formula

Irritation risk: Low

More about Leucine

Threonine~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Isoleucine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Tryptophan~0.2–0.4%

Formula

Irritation risk: Low

More about Tryptophan

Phenylalanine~0.2–0.4%

Formula

Irritation risk: Low

More about Phenylalanine

Tyrosine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Glycine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Polysorbate 80~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps water and oil mix together

More about Polysorbate 80

Serine~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

Adenosine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Cystine~0.25–0.45%

Formula

Irritation risk: Low

More about Cystine

Glutathione~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-oxidationMoisturizing

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Cyanocobalamin~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Deoxycytidine~0.2–0.4%

Formula

Irritation risk: Low

More about Deoxycytidine

Deoxyguanosine~0.2–0.4%

Formula

Irritation risk: Low

More about Deoxyguanosine

Thymidine~0.2–0.4%

Formula

Irritation risk: Low

More about Thymidine

Asparagine~0.2–0.4%

Formula

Irritation risk: Low

More about Asparagine

Aspartic acid~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Ornithine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid. Helps attract water to the upper layer of the skin

More about Ornithine

Glutamic acid~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Nicotinamide adenine dinucleotide~0.2–0.4%

Formula

Irritation risk: Low

More about Nicotinamide adenine dinucleotide

Proline~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Aminobutyric acid~0.25–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-agingAnti-inflammatory

Has been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing

More about Aminobutyric acid

Methionine~0.2–0.4%

Formula

Irritation risk: Low

More about Methionine

Taurine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-blemishAnti-inflammatoryAnti-oxidationEvens skin tone

Could be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness

More about Taurine

Hydroxyproline~0.2–0.4%

Key active

Irritation risk: Low

Works for

CleansingMoisturizingAnti-aging

Is helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking

More about Hydroxyproline

Glucosamine~0.25–0.45%

Formula

Irritation risk: Low

More about Glucosamine

Coenzyme a~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and dissolve other ingredients in a product

More about Coenzyme a

Gluconolactone~0.2–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-agingMoisturizingEvens skin toneExfoliationAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Sodium glucuronate~0.2–0.4%

Formula

Irritation risk: Low

More about Sodium glucuronate

Sodium

Not recognized

Uridine~0.2–0.4%

Formula

Irritation risk: Low

More about Uridine

Triphosphate

Not recognized

Thiamine diphosphate~0.2–0.4%

Formula

Irritation risk: Low

More about Thiamine diphosphate

Disodium flavine adenine dinucleotide~0.25–0.45%

Formula

Irritation risk: Low

More about Disodium flavine adenine dinucleotide

Nicotinamide adenine dinucleotide~0.2–0.4%

Formula

Irritation risk: Low

More about Nicotinamide adenine dinucleotide

Phosphate

Not recognized

Retinyl acetate~0.2–0.4%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-aging

More about Retinyl acetate

Inositol~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Inositol

Methyl

Not recognized

Deoxycytidine~0.2–0.35%

Formula

Irritation risk: Low

More about Deoxycytidine

Niacin~0.2–0.4%

Under-dosedIrritant · high

Irritation risk: High

Works for

MoisturizingAnti-agingAnti-blemishEvens skin tone

A form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect

More about Niacin

Niacinamide~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Pyridoxal

Not recognized

Pyridoxine~0.2–0.35%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidation

Might help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating

More about Pyridoxine

Biotin~0.15–0.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Calcium pantothenate~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingReduces irritation

Helps support skin barrier function improving skin hydration and reducing sensitivity

More about Calcium pantothenate

Folic acid~0.15–0.3%

Key active

Irritation risk: Low

Works for

Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid

Riboflavin~0.1–0.2%

Formula

Irritation risk: Low

More about Riboflavin

Tocopheryl phosphate~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

More about Tocopheryl phosphate

Ingredient list view

Water, Ethylhexyl palmitate, Cetearyl alcohol, Isodecyl neopentanoate, Glycerin, Synthetic wax, Pentaerythrityl tetracaprylate/tetracaprate, Dipalmitoylethyl hydroxyethylmonium methosulfate, Polyquaternium-37, Polymethyl methacrylate, Sodium hyaluronate, Steareth-21, Parfum, Ceteareth-20, Sucrose palmitate, Caprylic/capric triglyceride, Chlorphenesin, Glyceryl linoleate, Sorbitan oleate, Prunus amygdalus dulcis oil, Biosaccharide gum-1, Sorbitan laurate, Isopropyl alcohol, Potassium hydroxide, Glyceryl caprylate, Sodium anisate, Sodium levulinate, Salicornia herbacea extract, Phenoxyethanol, Methylisothiazolinone, Citric acid, Potassium sorbate, Myristyl malate phosphonic acid, Tocopherol, Sodium chloride, Glucose, Potassium chloride, Calcium chloride, Magnesium sulfate, Glutamine, Sodium phosphate, Sodium acetate, Ascorbic acid, Lysine hcl, Arginine, Alanine, Histidine, Valine, Leucine, Threonine, Isoleucine, Tryptophan, Phenylalanine, Tyrosine, Glycine, Polysorbate 80, Serine, Adenosine, Cystine, Glutathione, Cyanocobalamin, Deoxycytidine, Deoxyguanosine, Thymidine, Asparagine, Aspartic acid, Ornithine, Glutamic acid, Nicotinamide adenine dinucleotide, Proline, Aminobutyric acid, Methionine, Taurine, Hydroxyproline, Glucosamine, Coenzyme a, Gluconolactone, Sodium glucuronate, Unknown, Uridine, Unknown, Thiamine diphosphate, Disodium flavine adenine dinucleotide, Nicotinamide adenine dinucleotide, Unknown, Retinyl acetate, Inositol, Unknown, Deoxycytidine, Niacin, Niacinamide, Unknown, Pyridoxine, Biotin, Calcium pantothenate, Folic acid, Riboflavin, Tocopheryl phosphate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	FilorgaHydra-FillerYOUR PRODUCT	AHCHydrating Essential Real Eye Cream for Face	BLANC DIVARebirth Cream	LumeneNordic Ageless [AJATON] Radiant Youth Night Cream
Match	—	80%	79%	78%
Price	$47.00	$21.14−$25.86	$27.92−$19.08	$56.72+$9.72
Shared key ingredients	—	18 of 30	14 of 30	5 of 30
Key difference	—	Copper Tripeptide-1	Ceramide Np	Copper Heptapeptide-14 Pantothenate
Irritancy	High	High	Medium	Medium
Drying alcohol	Contains drying alcohol	Contains drying alcohol	—	—
	View product	Shop	Shop	Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 49 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
3
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
4
Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
5
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oilsmdpi.com
6
Methylisothiazolinone contact allergy: a reviewpubmed.ncbi.nlm.nih.gov
7
Vitamin E in dermatologyncbi.nlm.nih.gov
8
Vitamin E and Skin Healthlpi.oregonstate.edu
9
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Functionncbi.nlm.nih.gov
10
Safety Assessment of Magnesium Sulfate as Used in Cosmeticsncbi.nlm.nih.gov
11
Combination of amino acids reduces pigmentation in B16F0 melanoma cellsncbi.nlm.nih.gov
12
Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseasespatents.google.com
13
Safety Assessment of α-Amino Acids as Used in Cosmeticsciteseerx.ist.psu.edu
14
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
15
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trialonlinelibrary.wiley.com
16
Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiencyjamanetwork.com
17
Functional glycine receptor in cultured human keratinocytesonlinelibrary.wiley.com
18
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
19
Glutathione as a skin whitening agent: Facts, myths, evidence and controversiesijdvl.com
20
Glutathione for skin lightening: a regnant myth or evidence-based verity?ncbi.nlm.nih.gov
21
Glutathione for skin lightening for dermatologists and cosmetologistsijord.com
22
Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trialpubmed.ncbi.nlm.nih.gov
23
Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasisncbi.nlm.nih.gov
24
Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proofncbi.nlm.nih.gov
25
In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmnessncbi.nlm.nih.gov
26
gamma-Aminobutyric acid (A) receptor agonists accelerate cutaneous barrier recovery and prevent epidermal hyperplasia induced by barrier disruptionpubmed.ncbi.nlm.nih.gov
27
Wound healing activity of gamma-aminobutyric Acid (GABA) in ratspubmed.ncbi.nlm.nih.gov
28
Moisturizing effect of Gamma-aminobutyric acid for cosmetic applicationam-2017.weebly.com
29
Stimulation of human fibroblast collagen synthesis in vitro by gamma-aminobutyric acidpubmed.ncbi.nlm.nih.gov
30
Cosmeceuttical Critigue: Taurinemdedge.com
31
Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritusncbi.nlm.nih.gov
32
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acnencbi.nlm.nih.gov
33
The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoagingonlinelibrary.wiley.com
34
Applications of hydroxy acids: classification, mechanisms, and photoactivityncbi.nlm.nih.gov
35
The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative studydovepress.com
36
A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimenncbi.nlm.nih.gov
37
The use of polyhydroxy acids (PHAs) in photoaged skin
38
Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acidsonlinelibrary.wiley.com
39
An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patientsonlinelibrary.wiley.com
40
Aging Skin: Causes, Treatments, and Preventionsciencedirect.com
41
Clinical and cosmeceutical uses of hydroxyacidssciencedirect.com
42
Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Lightneostrata.neogen.gr
43
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
44
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
45
Cutaneous Metabolism of Vitamin B-6sciencedirect.com
46
Calcium pantothenate modulates gene expression in proliferating human dermal fibroblastsonlinelibrary.wiley.com
47
Dexpanthenol Modulates Gene Expression in Skin Wound Healing in vivokarger.com
48
Dexapanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritationtandfonline.com
49
Folic acid and creatine improve the firmness of human skin in vivopubmed.ncbi.nlm.nih.gov

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