Works for:
based on ingredients and %- Anti-aging
- Evens skin tone
- Moisturizing
- Anti-blemish
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 2
Key actives
Product Summary
Based on the ingredient list, "Dr. Denese - Body Rx Tightening Cream" can work well for skin moisturization. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Dr. Denese - Body Rx Tightening Cream ticks this box. Humectants in this product (arginine, glycerin and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide ng, cannabis sativa seed oil, arginine, bis-diglyceryl polyacyladipate-2 and butyrospermum parkii butter in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- this moisturizer contains an effective form of retinoids (vitamin A): hydroxypinacolone retinoate 0.01% - 0.05%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
- Another benefit is that this moisturizer contain ceramides (ceramide ng 0.35% - 0.60%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- This moistruizer also contains peptides (palmitoyl hexapeptide-12 0.30% - 0.50%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-aging
What does the product description say?
Powered by Retinol, Hyaluronic Acid, Peptides and more to visibly improve crepey skin, superficial lines, wrinkles on your arms, chest, abdomen, above your knees and more.
Source: Dr. Denese
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains hydroxypinacolone retinoate, palmitoyl hexapeptide-12.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: hydroxypinacolone retinoate. This ingredient is used for treating acne and can have a noticeable effect.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: pantothenic acid
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
Helps attract water to the upper layer of the skin and may help reduce inflammation in skin
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Evens skin tone
What does the product description say?
A body moisturizer and skin tightening treatment with the most innovative Retinol Technology to visibly tighten and even skin tone.
Source: Dr. Denese
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: hydroxypinacolone retinoate.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: punica granatum extract.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Moisturizing
What does the product description say?
Powered by Retinol, Hyaluronic Acid, Peptides and more to visibly improve crepey skin, superficial lines, wrinkles on your arms, chest, abdomen, above your knees and more.
Source: Dr. Denese
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
arginine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, bis-diglyceryl polyacyladipate-2.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ng, palmitoyl hexapeptide-12
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
Helps attract water to the upper layer of the skin and may help reduce inflammation in skin
A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture
Attracts water into the upper layer of the skin
A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
Helps soften the upper layer of the skin and reduce water loss from its surface
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An anti-oxidant. Is also called 6-paradol. It might be able to neutralize free radicals in skin. The manufacturer claims that it is able to stimulate synthesis of hyaluronic acid in skin, but there is no evidence of effectiveness of this ingredient so far. The only evidence of efficacy for this ingredient so far come from small lab tests. This ingredient comes together with Caprylic/Capric Triglyceride as part of the complex called SymDecanox HA produced by a cosmetic ingredient supplier Symrise.
A fruit extract that might help to attract water to the upper layer of the skin, but there is no evidence for any other benefits to the skin
An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products
Helps oil and water mix together while softening the upper layer of the skin
Used to create a thicker product consistency and soften the upper layer of the skin
Anti-oxidation
This product contains antioxidants (punica granatum extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
A plant extract that might have some anti-oxidant properties, but evidence of effectiveness in skin is lacking
An anti-oxidant. Is also called 6-paradol. It might be able to neutralize free radicals in skin. The manufacturer claims that it is able to stimulate synthesis of hyaluronic acid in skin, but there is no evidence of effectiveness of this ingredient so far. The only evidence of efficacy for this ingredient so far come from small lab tests. This ingredient comes together with Caprylic/Capric Triglyceride as part of the complex called SymDecanox HA produced by a cosmetic ingredient supplier Symrise.
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking
A fruit extract that might have some anti-oxidant effect
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Helps attract water to the upper layer of the skin and may help reduce inflammation in skin
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer
A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps soften the upper layer of the skin and reduce water loss from its surface
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
Potential irritants
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking
A plant extract that might have some anti-oxidant properties, but evidence of effectiveness in skin is lacking
A fruit extract that might have some anti-oxidant effect
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
An aromatic blend of unspecified and possibly irritating ingredients
A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A fruit extract that might help to attract water to the upper layer of the skin, but there is no evidence for any other benefits to the skin
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Comedogenic ingredients
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
All ingredients
A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer
A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps oil and water mix together while softening the upper layer of the skin
An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Helps soften the upper layer of the skin and reduce water loss from its surface
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Attracts water into the upper layer of the skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Helps attract water to the upper layer of the skin and may help reduce inflammation in skin
Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking
A plant extract that might have some anti-oxidant properties, but evidence of effectiveness in skin is lacking
A fruit extract that might help to attract water to the upper layer of the skin, but there is no evidence for any other benefits to the skin
A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective
A fruit extract that might have some anti-oxidant effect
A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine
Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
Used to create a thicker product consistency and soften the upper layer of the skin
An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
An anti-oxidant. Is also called 6-paradol. It might be able to neutralize free radicals in skin. The manufacturer claims that it is able to stimulate synthesis of hyaluronic acid in skin, but there is no evidence of effectiveness of this ingredient so far. The only evidence of efficacy for this ingredient so far come from small lab tests. This ingredient comes together with Caprylic/Capric Triglyceride as part of the complex called SymDecanox HA produced by a cosmetic ingredient supplier Symrise.
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
A preservative. It helps prevent bacterial growth in cosmetic products
An aromatic blend of unspecified and possibly irritating ingredients
Ingredient list view
Water, Cannabis sativa seed oil, Phenyl trimethicone, Dodecane, Methyl glucose sesquistearate, Cyclopentasiloxane, Cetearyl alcohol, Caprylic/capric triglyceride, Butyrospermum parkii butter, Glycerin, Glyceryl stearate citrate, Glyceryl caprylate, Dimethicone, Bis-diglyceryl polyacyladipate-2, Cetyl alcohol, Squalane, Sodium hyaluronate, Hydrolyzed sodium hyaluronate, Ceramide ng, Peg-10 phytosterol, Palmitoyl hexapeptide-12, Phospholipids, Retinyl palmitate, Pantothenic acid, Ascorbyl palmitate, Tocopheryl acetate, Bisabolol, Zingiber officinale root extract, Averrhoa carambola fruit extract, Passiflora incarnata fruit extract, Actinidia chinensis fruit extract, Garcinia mangostana bark extract, Ananas sativus fruit extract, Punica granatum extract, Litchi chinensis fruit extract, Zizyphus jujuba fruit extract, Psidium guajava fruit extract, Leuconostoc/radish root ferment filtrate, Dimethyl isosorbide, Hydroxypinacolone retinoate, C12-15 alkyl benzoate, Tribehenin, Sodium stearoyl glutamate, Arginine, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Polysorbate 60, Dimethiconol, Hydroxymethoxyphenyl decanone, Xanthan gum, Acrylates/c10-30 alkyl acrylate crosspolymer, Disodium edta, Phenoxyethanol, Ethylhexylglycerin, Parfum
- Hemp (Cannabis sativa L.) seed oil: Analytical and phytochemical characterization of unsaponifiable fraction
- Hemp (Cannabis sativa L.) as a Resource for Green Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety assessment of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmetics
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research
- Extract of Punica granatum inhibits skin photoaging induced by UVB irradiation
- Topical microemulsion containing Punica granatum extract: its control over skin erythema and melanin in healthy Asian subjects
- Safety Assessment of Punica granatum -Derived Ingredients as Used in Cosmetics
- Guava: phytochemical composition of a potential source of antioxidants for cosmetic and/or dermatological applications
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- Antiaging effects of retinoid hydroxypinacolone retinoate on skin models. (2018). Journal of the American Academy of Dermatology, 79(3), AB44. doi:10.1016/j.jaad.2018.05.215
- Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
- COMPOSITION COMPRISING A CROSSLINKED HYALURONIC ACID (HA) IN COMBINATION WITH A LOW-MOLECULAR HA AND/OR AN AGENT STIMULATING ENDOGENOUS HA SYNTHESIS
- Designing topical hyaluronic acid technology—Size does matter