What's In My Jar
CosMedix X-Cell+ Brightening Serum
CosMedix

CosMedix X-Cell+ Brightening Serum

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Retinol, Retinal + 6 more
Works well
What the product description says
“Made with proprietary LG-Retinex, a microencapsulated blend of Retinol, this age-defying serum is your daily dose for a more radiant-looking complexion.”
Source: Cosmedix

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal, retinol, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: ferulic acid, lactic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–1.1%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.45–1%
Lactic acidKey activeEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~2–3%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.5–2.3%
Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.5–1.1%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.7%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.9–1.3%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.55%
Evens skin tone
Retinol, Retinal + 7 more
Works well
What the product description says
“Made with a conditioning blend of skin-brightening Niacinamide and Waltheria Extract, this Retinol-infused formula exfoliates skin to visibly brighten the skin's appearance and helps reduce the look of dark spots and uneven skin tone and skin texture.”
Source: Cosmedix

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal, retinol.

In addition, this product contains lactic acid, niacinamide, salicylic acid. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: ferulic acid, glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–1.1%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.45–1%
Lactic acidKey activeEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~2–3%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.5–2.3%
Ferulic acidKey activeEffect: MediumA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.5–1.1%
Salicylic acidEffect: LowUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.6–1.4%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.15–0.7%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.9–1.3%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.55%
Exfoliation
Lactic acid, Salicylic acid + 2 more
Works well
What the product description says
“Exfoliate and intensely hydrate your complexion, while boosting skin's retention of moisture with X-Cell+ Brightening Serum.”
Source: Cosmedix

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: lactic acid, retinol, salicylic acid.

Lactic acidKey activeEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~2–3%
Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.6–1.4%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–1.1%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.55%
Moisturizing
Niacinamide, Glycerin + 9 more
Works well
What the product description says
“Exfoliate and intensely hydrate your complexion, while boosting skin's retention of moisture with X-Cell+ Brightening Serum.”
Source: Cosmedix

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, lactic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: glycosaminoglycans.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.5–2.3%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.4–5.1%
Lactic acidKey active· HumectantEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~2–3%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~1.1–1.7%
CarnitineKey activeEffect: Medium~0.9–1.35%
GlycosaminoglycansKey active· EmollientEffect: HighLong sugars that help attract water to the upper layer of the skin~0.5–1.15%
Palmaria palmata extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin~0.35–0.85%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.35–0.8%
Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.15–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.7%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.55%
Anti-blemish
Side benefit · Niacinamide, Salicylic acid + 4 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, retinal, retinol, salicylic acid. These ingredients is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.5–2.3%
Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.6–1.4%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–1.1%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.45–1%
CarnitineEffect: Low~0.9–1.35%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.55%
Anti-oxidation
Side benefit · Ferulic acid, Retinol + 8 more
Works well

This product contains antioxidants (ferulic acid, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia sinensis extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Ferulic acidKey activeEffect: HighA potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%~0.5–1.1%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.5–1.1%
Camellia sinensis extractKey activeEffect: MediumTea extract. Might be helpful in neutralizing free radicals in skin~0.15–0.55%
Palmaria palmata extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin~0.35–0.85%
Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.15–0.7%
Lavandula officinalis flower oilEffect: LowAm essential oil that is used as a fragrance~0.05–0.2%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.15–0.6%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.9–1.3%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.7%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.55%

Can it cause trouble?

Irritancy
7 strong irritants: Hamamelis virginiana water, Alcohol + 5 more — patch-test recommended
High risk
We flagged 18 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hamamelis virginiana waterA plant extract that can help calm down inflammation in skin. Can, however, itself be irritatingHigh~22–33%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~6.4–9.5%est.
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.6–1.4%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.9–1.3%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.5–1.1%est.
RetinalOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritatingHigh~0.45–1%est.
Bellis perennis flower extractA plant extract. Used as a fragrance. Can be irritatingHigh~0.2–0.7%est.
Citrus paradisi peel oilUsed as a fragrance. Can be irritatingHigh~0.05–0.25%est.
Lavandula officinalis flower oilAm essential oil that is used as a fragranceHigh~0.05–0.2%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~2–3%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.15–0.7%est.
GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.15–0.55%est.
Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.15–0.5%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.1–0.45%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.1–0.4%est.
Tetrasodium edtaHelps to stabilize the product formulationMedium~0.05–0.2%est.
EthylhexylglycerinA preservativeMedium~0.05–0.1%est.
Potassium sorbateA preservativeMedium~0.05–0.2%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Palmaria palmata extractRed algae extract that helps attract water to the upper layer of the skin3/5~0.35–0.85%est.
Alternatives
Cheaper, or higher on efficacy
REMEDY for healthy aging
REMEDY SCIENCE REMEDY for healthy aging
Cheaper68% match
$35.00
Beta‐Clarity BHA Drops
Glo Skin Beauty Beta‐Clarity BHA Drops
Cheaper62% match
$31.26
View all alternatives

User reviews

Would you recommend?
No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Hamamelis virginiana water~22–33%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can help calm down inflammation in skin. Can, however, itself be irritating

More about Hamamelis virginiana water
Alcohol~6.4–9.5%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Water~4.6–6.9%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.4–5.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Propanediol~2.7–4.1%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Lactic acid~2–3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Niacinamide~1.5–2.3%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Mannitol~1.1–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Salicylic acid~0.6–1.4%
Hero · Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishExfoliationAnti-inflammatoryAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Ascorbic acid~0.9–1.3%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Retinol~0.5–1.1%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Retinal~0.45–1%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-agingEvens skin tone

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

More about Retinal
Ferulic acid~0.5–1.1%
Key active
Irritation risk
Low
Works for
Anti-oxidationEvens skin toneAnti-inflammatoryAnti-aging

A potent anti-oxidant that has been shown to be effective in neutralizing free radicals in skin. There seem to have a synergetic effect of ferulic acid, vitamin E and C, meaning that when the ingredients are used together, they enhance each other's ability protect the skin against free radicals. Ferulic acid also helps to stabilize other ingredients - including vitamins C and E. It can help to even out the skin tone. Ferulic acid is approved for use as a sunscreen ingredient in Japan in concentrations up to 10%

More about Ferulic acid
Waltheria indica leaf extract~0.4–0.9%
Formula
Irritation risk
Low
More about Waltheria indica leaf extract
Palmaria palmata extract~0.35–0.85%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin

More about Palmaria palmata extract
Glycosaminoglycans~0.5–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

Long sugars that help attract water to the upper layer of the skin

More about Glycosaminoglycans
Phospholipids~0.35–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Carnitine~0.9–1.35%
Key active
Irritation risk
Low
Works for
CleansingMattifyingMoisturizingAnti-blemish
More about Carnitine
Bellis perennis flower extract~0.2–0.7%
Irritant · high
Irritation risk
High

A plant extract. Used as a fragrance. Can be irritating

More about Bellis perennis flower extract
Rumex occidentalis extract~0.15–0.65%
Formula
Irritation risk
Low
More about Rumex occidentalis extract
Glycyrrhiza glabra root extract~0.15–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Reduces rednessEvens skin toneAnti-oxidationAnti-inflammatoryAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Bisabolol~0.15–0.6%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Tocopherol~0.2–0.7%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Camellia sinensis extract~0.15–0.55%
Key active
Irritation risk
Low
Works for
Anti-oxidation

Tea extract. Might be helpful in neutralizing free radicals in skin

More about Camellia sinensis extract
Beta-carotene~0.1–0.4%
Formula
Irritation risk
Low

A colorant adding orange or bright yellow color

More about Beta-carotene
Morus nigra fruit extract~0.1–0.4%
Formula
Irritation risk
Low
More about Morus nigra fruit extract
Sodium gluconate~0.1–0.35%
Formula
Irritation risk
Low

Helps stabilize product formulations

More about Sodium gluconate
Gluconolactone~0.15–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-agingEvens skin toneExfoliationMoisturizingAnti-blemishAnti-oxidation

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone
Sodium citrate~0.15–0.5%
Irritant · medium
Irritation risk
Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate
Dextrin~0.15–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin
Citric acid~0.1–0.45%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Xanthan gum~0.1–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Leuconostoc/radish root ferment filtrate~0.1–0.4%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Citrus paradisi peel oil~0.05–0.25%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Citrus paradisi peel oil
Lavandula officinalis flower oil~0.05–0.2%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

Am essential oil that is used as a fragrance

More about Lavandula officinalis flower oil
Tetrasodium edta~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Helps to stabilize the product formulation

More about Tetrasodium edta
Phenoxyethanol~0.05–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Potassium sorbate~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Ingredient list view

Hamamelis virginiana water, Alcohol, Water, Glycerin, Propanediol, Lactic acid, Niacinamide, Mannitol, Salicylic acid, Ascorbic acid, Retinol, Retinal, Ferulic acid, Waltheria indica leaf extract, Palmaria palmata extract, Glycosaminoglycans, Phospholipids, Carnitine, Bellis perennis flower extract, Rumex occidentalis extract, Glycyrrhiza glabra root extract, Bisabolol, Tocopherol, Camellia sinensis extract, Beta-carotene, Morus nigra fruit extract, Sodium gluconate, Gluconolactone, Sodium citrate, Dextrin, Citric acid, Xanthan gum, Leuconostoc/radish root ferment filtrate, Citrus paradisi peel oil, Lavandula officinalis flower oil, Tetrasodium edta, Phenoxyethanol, Ethylhexylglycerin, Potassium sorbate

Compare prices

Retailers ranked by price — lowest first.

Find on Amazon
Search
Cosmedix
$84.00
Buy

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CosMedixX-Cell+ Brightening SerumYOUR PRODUCTREMEDY SCIENCEREMEDY for healthy agingNoble PanaceaThe Exceptional RetiNAD+ Renewal BoosterGlo Skin BeautyBeta‐Clarity BHA Drops
Match—68%64%62%
Price$84.00$35.00−$49.00$240.00+$156.00$31.26−$52.74
Shared key ingredients—8 of 167 of 165 of 16
Key difference—Glycolic AcidHexapeptide-9Glycolic Acid
Irritancy High Medium Medium High
Drying alcohol Contains drying alcohol —— Contains drying alcohol
View product Shop Shop Shop
  • matches yours
  • differs
  • cheaper

More alternatives: pureclinica Triple Strength Vitamin C, E & Ferulic Acid SerumPCA SKIN Intensive Clarity Treatment 0.5 Percent Pure Retinol

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 29 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
  3. 3
    Dual Effects of Alpha-Hydroxy Acids on the Skinpdfs.semanticscholar.org
  4. 4
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  5. 5
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  6. 6
    Salicylic acid as a peeling agent: a comprehensive reviewncbi.nlm.nih.gov
CosMedix X-Cell+ Brightening Serum
CosMedixX-Cell+ Brightening Serum
Buy at Cosmedix$84.00Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Cosmedix$84.00Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.