PRODUCT REVIEW
Theramid Clinical Vitamin A
Appears in
2 routines
Added by Martyna
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Product summary
What can the product work for?
Anti-aging
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
retinol
0.4% -
0.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
retinal
0.35% -
0.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
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Evens skin tone
retinal
0.35% -
0.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
retinol
0.4% -
0.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Show more
Moisturizing
ceramide ng
0.3% -
0.75%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
lactococcus ferment lysate
0.3% -
0.75%
Irritation risk:
Concentration: Effectiveness: HIGH
Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin
caprylic/capric triglyceride
2.8% -
4.1%
Irritation risk:
Concentration: Effectiveness: HIGH
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
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Anti-blemish
retinol
0.4% -
0.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Concentration: Effectiveness: HIGH
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
retinal
0.35% -
0.8%
Irritation risk:
Concentration: Effectiveness: HIGH
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
Exfoliation
retinol
0.4% -
0.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
lactic acid
0.05% -
0.25%
Irritation risk:
Concentration: Insufficient!
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)
Anti-oxidation
retinol
0.4% -
0.9%
Irritation risk:
Concentration: Effectiveness: HIGH
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
lactococcus ferment lysate
0.3% -
0.75%
Irritation risk:
Concentration: Effectiveness:
LOW
Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin
tocopherol
0.2% -
0.75%
Irritation risk:
Concentration: Insufficient!
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Honesty check
How honest is this product?
Promise | Can it deliver? |
---|---|
Anti-aging | |
Moisturizing | |
Evens skin tone |
Total Promises Fulfilled score:
100/100.
Buy now
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 1
Potential irritants
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-aging,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
retinol
0.4% -
0.9%
Irritation risk:
Works for:
Anti-aging,
Anti-oxidation,
Exfoliation,
Mattifying,
Anti-blemish,
Evens skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Show more
Comodogenic ingredients
plankton extract
0.2% -
0.8%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Can help attract water to the upper layer of the skin
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Theramid - Clinical Vitamin A | Some By Mi - Retinol Intense Reactivating Serum Sponsored | INNBEAUTY PROJECT - Retinol Remix 1% Retinol Treatment | The Ordinary - Advanced Granactive Retinoid 2% Emulsion | cocokind - beginner retinol gel 0.1% | Boost Lab - Retinol Night Renewal Serum | Zelens - Power A Retexturising and Renewing Serum | Plaisir - Renewing Retinol Booster Serum | The INKEY List CA - Retinol Serum | e.l.f. Cosmetics - YOUTH BOOSTING ADVANCED NIGHT RETINOID SERUM | Beauty Pie - Youthbomb Double-retinol Action Skin Overhaul Serum | Trinny London - Overnight sensation | |
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WIMJ similarity score |
61%
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73%
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71%
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71%
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66%
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Key ingredients | Common:
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Irritancy | IRRITANCY
HIGH
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HIGH
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HIGH
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MEDIUM
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HIGH
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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HIGH
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Ingredients & concentrations
All ingredients
Key Actives
retinol
0.4% -
0.9%
Irritation risk:
Works for:
Anti-aging,
Anti-oxidation,
Exfoliation,
Mattifying,
Anti-blemish,
Evens skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-aging,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
Show more
Potential irritants
hydroxypinacolone retinoate
0.05% -
0.3%
Irritation risk:
Works for:
Evens skin tone,
Anti-blemish,
Anti-aging,
Exfoliation
A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.
retinol
0.4% -
0.9%
Irritation risk:
Works for:
Anti-aging,
Anti-oxidation,
Exfoliation,
Mattifying,
Anti-blemish,
Evens skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Show more
Comodogenic ingredients
plankton extract
0.2% -
0.8%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Can help attract water to the upper layer of the skin
All ingredients
glycerin
4.1% -
6.1%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
coco-caprylate/caprate
3.6% -
5.4%
Irritation risk:
Works for:
Moisturizing
Helps to soften the upper layer of the skin without creating a greasy texture
Show more
Ingredient list view
Water, Glycerin, Coco-caprylate/caprate, Caprylic/capric triglyceride, Propanediol, Coco-caprylate, Dimethyl isosorbide, Polyglyceryl-6 distearate, Cellulose acetate butyrate, Cetyl alcohol, Hydroxypinacolone retinoate, Retinol, Retinal, Lactococcus ferment lysate, Plankton extract, Ceramide ng, Tocopherol, Ethylhexylglycerin, Jojoba esters, Lecithin, Pullulan, Sclerotium gum, Xanthan gum, Tricaprylin, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Caprylyl glycol, Silica, Sodium chloride, Lactic acid, Citric acid, Phenoxyethanol, Sodium benzoate
Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Safety Assessment of Alkyl Esters as Used in Cosmetics
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- Antiaging effects of retinoid hydroxypinacolone retinoate on skin models. (2018). Journal of the American Academy of Dermatology, 79(3), AB44. doi:10.1016/j.jaad.2018.05.215
- Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Safety Assessment of Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate as Used in Cosmetics
- Epidermal and dermal effects of topical lactic acid