Perricone MD The Acne Relief Soothing Regimen

Perricone MD The Acne Relief Soothing Regimen

Efficacy100/100IrritancyHigh

Works for

Cleansing
Sodium cocoyl isethionate, Ceteareth-20 + 16 more
Cleanses gently
What the product description says
“Thoroughly cleanses, reduces excess oil, unclogs pores.”
Source: Perricone MD

This product works by removing dirt and oil from the surface of the skin. It uses a combination of mild cleansing agents (carbomer, ceteareth-20, ceteareth-30, cetearyl alcohol, cetyl alcohol, decyl glucoside, glyceryl caprylate, glyceryl stearate, hydrogenated palm glycerides, laureth-7, methyl glucose sesquistearate, peg-100 stearate, peg-20 methyl glucose sesquistearate, polyglyceryl-3 methylglucose distearate, polysorbate 20, sodium cocoyl isethionate, xanthan gum) and should be able to cleanse the skin gently. Still keep in mind that any cleansing can disrupt the skin barrier, and most people do not need to cleanse their skin more than once per day.

Even though this formulation is mild, the following cleansing agents could trigger an irritation or allergy for some people: decyl glucoside

Sodium cocoyl isethionateEffect: HighHelps water and oil mix together. Can be used as a cleansing agent~8.4–10.3%
Ceteareth-20Effect: HighHelps oil and water mix together. Has some emollient properties~0.4–0.6%
Ceteareth-30Effect: High~0.3–0.55%
Cetearyl alcoholEffect: HighA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.3–0.55%
Cetyl alcoholEffect: HighA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.3–0.55%
Decyl glucosideEffect: HighHelps oil and water mix together. Can be irritating~0.3–0.55%
Glyceryl caprylateEffect: HighAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.3–0.55%
Glyceryl stearateEffect: HighAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.55%
Hydrogenated palm glyceridesEffect: HighAn emollient that softens the skin~0.3–0.55%
Methyl glucose sesquistearateEffect: HighHelps water and oil mix together~0.3–0.55%
Peg-100 stearateEffect: HighHelps oil and water mix togehter and creates a nice product texture~0.3–0.55%
Xanthan gumEffect: HighUsed to create a thicker product consistency~0.25–0.4%
Laureth-7Effect: HighHelps oil and water mix together~0.25–0.45%
Peg-20 methyl glucose sesquistearateEffect: HighHelps oil and water mix together~0.25–0.45%
Polyglyceryl-3 methylglucose distearateEffect: HighHelps water and oil mix together~0.25–0.45%
Polysorbate 20Effect: HighHelps oil and water mix together~0.25–0.45%
CarbomerEffect: HighHelps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations~0.2–0.4%
LecithinEffect: High, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.55%
Exfoliation
Side benefit · Salicylic acid, Retinol + 2 more
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol, salicylic acid.

Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)2%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.35%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.35%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.4%

Can it cause trouble?

Irritancy
3 strong irritants: Sd alcohol 40-b, Retinol + 1 more — patch-test recommended
High risk
We flagged 34 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Sd alcohol 40-bCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.4–0.6%est.
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High2%
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.2–0.35%est.
Calendula officinalis flower extractA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritatingHigh~0.2–0.35%est.
Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.3–0.55%est.
Sodium cocoyl isethionateHelps water and oil mix together. Can be used as a cleansing agentMedium~8.4–10.3%est.
PolyacrylamideUsed to improve product texture and help oil and water mix togetherMedium~1.6–2%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~1.1–1.4%est.
Laureth-7Helps oil and water mix togetherMedium~0.6–0.9%est.
PvpHelps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skinMedium~0.4–0.65%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.4%est.
Potassium sorbateA preservativeMedium~0.25–0.45%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.6%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.4%est.
Peg-20 methyl glucose sesquistearateHelps oil and water mix togetherMedium~0.25–0.45%est.
Methyl glucose sesquistearateHelps water and oil mix togetherMedium~0.3–0.55%est.
Coco-caprylateAn emollient that softens skin and creates a nice product textureMedium~0.3–0.55%est.
TriethylhexanoinHelps soften the upper layer of the skinMedium~0.2–0.35%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.3–0.55%est.
Cannabis sativa seed oilA plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layerMedium~0.3–0.55%est.
Mauritia flexuosa fruit oilHelps soften the upper layer of the skinMedium~0.2–0.4%est.
Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherMedium~0.25–0.45%est.
Cannabidiol - derived from extract or tincture or resin of cannabisCBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier functionMedium~0.3–0.55%est.
Caprylhydroxamic acidA preservativeMedium~0.2–0.4%est.
1,2-hexanediolA preservativeMedium~0.2–0.4%est.
Aluminum starch octenylsuccinateUsed to thicken the product's consistencyMedium~0.2–0.4%est.
Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~0.3–0.55%est.
Citrullus lanatus fruit extractA plant extract that can contain an antioxidant compoundMedium~0.2–0.4%est.
Pyrus malus fruit extractCan have some moisturizing properties due to its sugar contentMedium~0.2–0.4%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.35–0.65%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.4–0.6%est.
Lens esculenta fruit extractA plant extract containing sugars that might help attract water to the upper layer of the skin. Is claimed by the manufacturer to help reduce pore size but evidence is lackingMedium~0.2–0.35%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.15–0.3%est.
Comedogenic
6 ingredients rated 2 or more on the 0–5 pore-clogging scale
6 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~5.2–6.3%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.55%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.55%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.55%est.
Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.35–0.65%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.4–0.6%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Glycerin~25–31%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Sodium cocoyl isethionate~8.4–10.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together. Can be used as a cleansing agent

More about Sodium cocoyl isethionate
Ethylhexyl palmitate~5.2–6.3%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Silica cetyl silylate~3.8–4.7%
Formula
Sucrose~2.7–3.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Can help attract water to the upper layer of the skin. In crystal form, it can work as a gentle exfoliant, gentler than the salt scrub. Helps stabilize the emulsion

More about Sucrose
Squalane~2.4–2.9%
Formula
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Polyacrylamide~1.6–2%
Irritant · medium
Irritation risk
Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide
Water~1.3–1.6%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylyl glycol~1.1–1.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
C13-14 isoparaffin~0.9–1.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Laureth-7~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Phenoxyethanol~0.5–0.75%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Water~0.45–0.65%
Formula
Irritation risk
Low

Plain old water

More about Water
Sd alcohol 40-b~0.4–0.6%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Sd alcohol 40-b
Glycerin~0.4–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
C12-15 alkyl lactate~0.45–0.65%
Formula
Pvp~0.4–0.65%
Irritant · medium
Irritation risk
Medium

Helps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skin

More about Pvp
Dimethicone~0.45–0.65%
Formula
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Polysorbate 20~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Citrulline~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Citrulline
Squalane~0.3–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Lactic acid~0.25–0.4%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Succinic acid~0.2–0.4%
Formula
Irritation risk
Low
More about Succinic acid
Polyacrylamide~0.3–0.55%
Irritant · medium
Irritation risk
Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide
Dimethicone/vinyl dimethicone crosspolymer~0.2–0.4%
Formula
Irritation risk
Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer
C13-14 isoparaffin~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Laureth-7~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Phenoxyethanol~0.25–0.45%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sodium benzoate~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Salicylic acid2%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-blemishExfoliationAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Water~0.2–0.4%
Formula
Irritation risk
Low

Plain old water

More about Water
Sd alcohol 40-b~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Sd alcohol 40-b
Glycerin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dicaprylyl ether~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Niacinamide~0.2–0.4%
Formula
Irritation risk
Low
Works for
Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Citrulline~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Citrulline
Arginine~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Methyl gluceth-20~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and soften it

More about Methyl gluceth-20
Cetearyl alcohol~0.3–0.55%
Comedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Carbomer~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Tocopheryl acetate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Retinol~0.2–0.35%
Key activeIrritant · high
Irritation risk
High
Works for
MattifyingEvens skin toneAnti-blemishExfoliationAnti-oxidationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Citric acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium hydroxide~0.2–0.4%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Disodium edta~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Peg-20 methyl glucose sesquistearate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-20 methyl glucose sesquistearate
Peg-100 stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Methyl glucose sesquistearate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Methyl glucose sesquistearate
Polysorbate 20~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Phenoxyethanol~0.25–0.45%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sodium benzoate~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Water~0.2–0.4%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Betaine~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Coco-caprylate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that softens skin and creates a nice product texture

More about Coco-caprylate
Triethylhexanoin~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Triethylhexanoin
Sodium acrylates copolymer~0.3–0.55%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Calendula officinalis flower extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Cannabis sativa seed oil~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer

More about Cannabis sativa seed oil
Ceteareth-30~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing
More about Ceteareth-30
Cetearyl alcohol~0.3–0.55%
Comedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Mauritia flexuosa fruit oil~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Mauritia flexuosa fruit oil
Polyglyceryl-3 methylglucose distearate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-3 methylglucose distearate
Glyceryl caprylate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Cannabidiol - derived from extract or tincture or resin of cannabis~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritationAnti-blemishAnti-oxidation

CBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function

More about Cannabidiol - derived from extract or tincture or resin of cannabis
Bisabolol~0.2–0.35%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Ceramide np~0.3–0.55%
Formula
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Dipotassium glycyrrhizate~0.2–0.4%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Tocopherol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Caprylhydroxamic acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
1,2-hexanediol~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Decyl glucoside~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside
Water~0.2–0.4%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Aluminum starch octenylsuccinate~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Used to thicken the product's consistency

More about Aluminum starch octenylsuccinate
Cetearyl alcohol~0.3–0.55%
Comedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Bis-diglyceryl polyacyladipate-2~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and reduce water loss from its surface

More about Bis-diglyceryl polyacyladipate-2
Cetyl alcohol~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Vitis vinifera seed oil~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil
Dicaprylyl ether~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Hydrogenated palm kernel glycerides~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Hydrogenated palm kernel glycerides
Squalane~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Calendula officinalis flower extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Cannabis sativa seed oil~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

A plant oil that due to its high linoleic acid content can help strengthen skin's barrier function and soften its upper layer

More about Cannabis sativa seed oil
Cannabidiol - derived from extract or tincture or resin of cannabis~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritationAnti-blemishAnti-oxidation

CBD. Can bind to skin cell receptors and can reduce inflammation, itching, and help support skin barrier function

More about Cannabidiol - derived from extract or tincture or resin of cannabis
Glyceryl caprylate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate
Bisabolol~0.2–0.35%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Ectoin~0.2–0.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Citrullus lanatus fruit extract~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can contain an antioxidant compound

More about Citrullus lanatus fruit extract
Allantoin~0.2–0.35%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Dipotassium glycyrrhizate~0.2–0.4%
Formula
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Xanthan gum~0.25–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Pyrus malus fruit extract~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Hydrogenated palm glycerides~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin

More about Hydrogenated palm glycerides
Tocotrienols~0.2–0.4%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-aging

A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms

More about Tocotrienols
Tocopherol~0.3–0.6%
Formula
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Glycine soja oil~0.35–0.65%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil
Caprylhydroxamic acid~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
Ceteareth-20~0.4–0.6%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
1,2-hexanediol~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Sodium polyacrylate~0.45–0.65%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Lens esculenta fruit extract~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A plant extract containing sugars that might help attract water to the upper layer of the skin. Is claimed by the manufacturer to help reduce pore size but evidence is lacking

More about Lens esculenta fruit extract
Sodium lactate~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Elaeis guineensis oil~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil
Sodium pca~0.15–0.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca
Potassium sorbate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium benzoate~0.15–0.25%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ingredient list view

Glycerin, Sodium cocoyl isethionate, Ethylhexyl palmitate, Silica cetyl silylate, Sucrose, Squalane, Polyacrylamide, Water, Caprylyl glycol, C13-14 isoparaffin, Laureth-7, Phenoxyethanol, Water, Sd alcohol 40-b, Glycerin, C12-15 alkyl lactate, Pvp, Dimethicone, Polysorbate 20, Citrulline, Squalane, Lactic acid, Succinic acid, Polyacrylamide, Dimethicone/vinyl dimethicone crosspolymer, C13-14 isoparaffin, Laureth-7, Phenoxyethanol, Sodium benzoate, Potassium sorbate, Salicylic acid, Water, Sd alcohol 40-b, Glycerin, Dicaprylyl ether, Niacinamide, Citrulline, Arginine, Methyl gluceth-20, Cetearyl alcohol, Carbomer, Xanthan gum, Tocopheryl acetate, Retinol, Citric acid, Sodium hydroxide, Disodium edta, Peg-20 methyl glucose sesquistearate, Peg-100 stearate, Glyceryl stearate, Methyl glucose sesquistearate, Polysorbate 20, Phenoxyethanol, Sodium benzoate, Potassium sorbate, Water, Glycerin, Betaine, Coco-caprylate, Triethylhexanoin, Sodium acrylates copolymer, Calendula officinalis flower extract, Cannabis sativa seed oil, Ceteareth-30, Cetearyl alcohol, Glyceryl stearate, Mauritia flexuosa fruit oil, Polyglyceryl-3 methylglucose distearate, Glyceryl caprylate, Cannabidiol - derived from extract or tincture or resin of cannabis, Bisabolol, Lecithin, Ceramide np, Dipotassium glycyrrhizate, Tocopherol, Caprylhydroxamic acid, 1,2-hexanediol, Decyl glucoside, Water, Glycerin, Glyceryl stearate, Aluminum starch octenylsuccinate, Cetearyl alcohol, Bis-diglyceryl polyacyladipate-2, Cetyl alcohol, Vitis vinifera seed oil, Dicaprylyl ether, Hydrogenated palm kernel glycerides, Squalane, Calendula officinalis flower extract, Cannabis sativa seed oil, Cannabidiol - derived from extract or tincture or resin of cannabis, Glyceryl caprylate, Bisabolol, Ectoin, Citrullus lanatus fruit extract, Allantoin, Dipotassium glycyrrhizate, Xanthan gum, Pyrus malus fruit extract, Hydrogenated palm glycerides, Tocotrienols, Tocopherol, Glycine soja oil, Caprylhydroxamic acid, Ceteareth-20, 1,2-hexanediol, Sodium polyacrylate, Lens esculenta fruit extract, Sodium lactate, Elaeis guineensis oil, Sodium pca, Potassium sorbate, Sodium benzoate

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Perricone MD
$199.00 Out of stock
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Perricone MDThe Acne Relief Soothing RegimenYOUR PRODUCTMedicubeKojic Acid Turmeric Vita Capsule Cleansing FoamYEOUTHVitamin C Facial Cleanser Day/Night CreamCeraVeGel Moussant Anti-Imperfections
Match—60%57%53%
Price—$26.80$41.90—
Shared key ingredients—9 of 468 of 468 of 46
Key difference—Sodium HyaluronateSodium Ascorbyl PhosphateGlycolic Acid
Irritancy High High Medium Low
Drying alcohol Contains drying alcohol ———
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More alternatives: Cleaning Supply Retinol 24 + Peptide Face Wash, Smoothing, Sulfate-FreeMurad Time Release Blemish Cleanser

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Product summary

"Perricone MD - The Acne Relief Soothing Regimen" is effective for: Anti-inflammatory, Moisturizing, Anti-aging, Exfoliation, Anti-blemish and Evens skin tone

Ingredient callouts

  • This product contains acids (lactic acid 0.80% - 1.20%). Their concentration is low, and they will not have a strong exfoliating effect. Instead, they work to support the skin natural acid mantle and to attract water (as humectants). Lactic acid is particularly good in attracting water to the upper layer of the skin and improving the skin barrier.
  • What makes this product special is the inclusion of Cannabidiol, or CBD (0.30% - 0.50%). CBD is a new active in skincare, and the research about it is still ongoing. It is already clear though that CBD can bind to skin cell receptors. It can help reduce inflammation, itching, and help support skin barrier function. It also has a promise in reducing acne.
  • This product contains an effective form of Retinoids (vitamin A): retinol 0.25% - 0.45%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
  • Ceramides (ceramide np 0.30% - 0.60%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Humectants (sodium pca 0.10% - 0.25%, sodium lactate 0.15% - 0.25%, glycerin 0.30% - 0.60%, betaine 0.25% - 0.45%, glycerin 0.30% - 0.55%, arginine 0.25% - 0.45%, glycerin 0.30% - 0.60%, citrulline 1.40% - 1.70%, glycerin 3.80% - 4.60% and citrulline 0.25% - 0.45%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.

Price

The product retails for 199.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 44 studies and safety reviews.

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Perricone MD The Acne Relief Soothing Regimen
Perricone MDThe Acne Relief Soothing Regimen

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