PRODUCT REVIEW
Perricone MD Cold Plasma Plus+ Essentials Regimen
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Product summary
What can the product work for?
Anti-aging
What does the product description say?
Targets and dramatically improves the feel and appearance of loss of radiance, uneven texture, uneven tone, discoloration, redness, enlarged pores, lines, wrinkles and loss of firmness.
glycolic acid
0.4% -
0.6%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
palmitoyl tetrapeptide-7
0.5% -
0.8%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
palmitoyl tripeptide-1
0.6% -
0.85%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
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Evens skin tone
What does the product description say?
Targets and dramatically improves the feel and appearance of loss of radiance, uneven texture, uneven tone, discoloration, redness, enlarged pores, lines, wrinkles and loss of firmness.
glycolic acid
0.4% -
0.6%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
chrysin
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
n-hydroxysuccinimide
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness:
LOW
Is claimed to be able to brighten skin tone by removing some blood-related pigmented compounds in skin (hemoglobin and related elements) but solid research is missing. Can be irritating
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Exfoliation
glycolic acid
0.4% -
0.6%
Irritation risk:
Concentration: Effectiveness: HIGH
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
zinc gluconate
0.25% -
0.45%
Irritation risk:
Concentration: Insufficient!
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
copper gluconate
0.25% -
0.4%
Irritation risk:
Concentration: Insufficient!
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
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Moisturizing
copper tripeptide-1
0.3% -
0.55%
Irritation risk:
Concentration: Effectiveness: HIGH
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
acetyl hexapeptide-8
0.65% -
0.95%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
acetyl tetrapeptide-11
0.25% -
0.45%
Irritation risk:
Concentration: Effectiveness: HIGH
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Show more
Anti-oxidation
chrysin
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Might be helpful in reducing fine lines and wrinkles, as well as lightening the skin, but solid evidence is missing. Could somewhat help in reducing the darkness of the under-eye area. Helps to neutralise free radicals in skin
hydrolyzed myrtus communis leaf extract
0.35% -
0.65%
Irritation risk:
Concentration: Effectiveness:
LOW
tetrahexyldecyl ascorbate
1.1% -
1.4%
Irritation risk:
Concentration: Insufficient!
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
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Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Evens skin tone |
Total Promises Fulfilled score:
100/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 9
Potential irritants
glycolic acid
0.4% -
0.6%
Irritation risk:
Works for:
Evens skin tone,
Exfoliation,
Anti-aging,
Anti-blemish
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
hydrolyzed myrtus communis leaf extract
0.35% -
0.65%
Irritation risk:
Works for:
Anti-inflammatory,
Anti-oxidation
Show more
Comodogenic ingredients
isopropyl palmitate
4.6% -
5.6%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps soften the upper layer of the skin and create a thicker product consistency
cetearyl alcohol
2.5% -
3%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Show more
User reviews (0)
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| WIMJ similarity score |
42%
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| Key ingredients | Common:
Other:
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| Irritancy | IRRITANCY
HIGH
| IRRITANCY
MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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MEDIUM
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HIGH
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Ingredients & concentrations
All ingredients
Key Actives
zinc gluconate
0.25% -
0.45%
Irritation risk:
Works for:
Moisturizing,
Anti-blemish,
Exfoliation,
Evens skin tone,
Anti-aging,
Anti-inflammatory,
Anti-oxidation
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
zinc gluconate
0.2% -
0.4%
Irritation risk:
Works for:
Moisturizing,
Evens skin tone,
Anti-aging,
Anti-inflammatory,
Anti-oxidation,
Anti-blemish,
Exfoliation
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Show more
Potential irritants
glycolic acid
0.4% -
0.6%
Irritation risk:
Works for:
Evens skin tone,
Exfoliation,
Anti-aging,
Anti-blemish
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
hydrolyzed myrtus communis leaf extract
0.35% -
0.65%
Irritation risk:
Works for:
Anti-inflammatory,
Anti-oxidation
Show more
Comodogenic ingredients
isopropyl palmitate
4.6% -
5.6%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps soften the upper layer of the skin and create a thicker product consistency
cetearyl alcohol
2.5% -
3%
Irritation risk: Comedogenicity: Medium
Works for:
Cleansing,
Moisturizing
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Show more
All ingredients
isopropyl palmitate
4.6% -
5.6%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps soften the upper layer of the skin and create a thicker product consistency
glycerin
4% -
4.9%
Irritation risk:
Works for:
Moisturizing
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Show more
Ingredient list view
Water, Isopropyl palmitate, Glycerin, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, Butylene glycol, Phosphatidylcholine, Tetrahexyldecyl ascorbate, Dimethyl mea, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Tyrosine, Echium plantagineum seed oil, Glycolic acid, Hydrolyzed myrtus communis leaf extract, Copper tripeptide-1, Helianthus annuus seed oil, Magnesium aspartate, Zinc gluconate, Copper gluconate, Ethylhexylglycerin, Rosmarinus officinalis leaf extract, Sodium hyaluronate, Retinyl palmitate, Disodium edta, Carbomer, Ceteareth-20, Hydrogenated vegetable glycerides, Dimethicone, Caprylyl glycol, Polysorbate 20, Phenoxyethanol, Sorbic acid, Potassium sorbate, Water, Isopropyl palmitate, Cetearyl alcohol, Glyceryl stearate, Jojoba esters, Peg-100 stearate, Ceteareth-20, Benzyl alcohol, Hydrogenated olive oil, Olea europaea fruit oil, Tetrahexyldecyl ascorbate, Phosphatidylcholine, Acetyl tetrapeptide-5, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Echium plantagineum seed oil, Helianthus annuus seed oil, Copper tripeptide-1, Magnesium aspartate, Zinc gluconate, Sodium hyaluronate, Rosmarinus officinalis leaf extract, Copper gluconate, N-hydroxysuccinimide, Chrysin, Disodium edta, Dimethicone, Glycerin, Butylene glycol, Steareth-20, Dimethicone crosspolymer, Silica, Titanium dioxide, Ci 77891, Iron oxides, Ci 77491, Water, C12-15 alkyl benzoate, Caprylic/capric triglyceride, Dicaprylyl carbonate, Propanediol, Shea butter ethyl esters, Glycerin, Cetearyl alcohol, Behenyl alcohol, Bentonite, Glyceryl stearate, Hydrogenated vegetable glycerides citrate, Dimethicone, Isoamyl laurate, Hydrogenated vegetable oil, Hydrogenated soybean oil, Butylene glycol, Sodium hyaluronate, Copper tripeptide-1, Phosphatidylcholine, Acetyl hexapeptide-8, Acetyl tetrapeptide-11, Acetyl tetrapeptide-9, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Dimethyl mea, Tetrahexyldecyl ascorbate, Tyrosine, Hydrolyzed myrtus communis leaf extract, Rosmarinus officinalis leaf extract, Polysorbate 20, Dimethyl isosorbide, Polysilicone-11, Phenoxyethanol, Petrolatum, Hydrogenated olive oil, Caprylyl glycol, Coco-glucoside, Hydrogenated jojoba oil, Echium plantagineum seed oil, Citric acid, Glycolic acid, Helianthus annuus seed oil, Glycine soja lipids, Carbomer, Disodium edta, Phytosterols, Ethylhexylglycerin
Sources
- Final Report on the Safety Assessment of Isopropyl Isostearate
- Glycerol and the skin: holistic approach to its origin and functions
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Healing fats of the skin: the structural and immunologic roles of the omega-6 and omega-3 fatty acids
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review
- Antimicrobial and antioxidative activity of extracts and essential oils of Myrtus communis L.
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
- Topical Peptide Treatments with Effective Anti-Aging Results
- Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural study
- Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compounds
- Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Care
- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
- Effect of topically applied lipids on surfactant-irritated skin
- Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countries
- Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokines
- Zinc salts in dermatology
- An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
- Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins
- Evaluation of the effects of topical zinc gluconate in wound healing
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gel
- Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmetics
- Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responses
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oil
- Anti-photoageing and anti-melanogenesis activities of chrysin
- Chrysin Protects Epidermal Keratinocytes from UVA- and UVB-Induced Damage
- Inhibition of melanogenesis by 5,7-dihydroxyflavone (chrysin) via blocking adenylyl cyclase activity
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Response