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Perricone MD Classic Firming Regimen
Perricone MD

Perricone MD Classic Firming Regimen

Efficacy100/100IrritancyHigh
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Works for

1 of 1 advertised claim delivered

Moisturizing
Urea, Tyrosine + 15 more
Strong evidence
What the product description says
“This firming face cream delivers instant hydration, while visibly smoothing, plumping and firming skin over time, leaving a radiant complexion.”
Source: Perricone MD

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetearyl alcohol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: urea

TyrosineKey activeEffect: High~0.3–0.5%
Zinc gluconateKey activeEffect: HighTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.3–0.5%
Peg/ppg-18/18 dimethiconeKey activeEffect: HighA silicone that mixes with water creating nice light-weight product texture~0.3–0.55%
Aleurites moluccanus seed oilKey activeEffect: HighHelps soften the upper layer of the skin~0.3–0.5%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.3–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.6%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.55%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.25–0.45%
Hydrolyzed wheat proteinKey active· HumectantEffect: MediumCan help attract water to the upper layer of the skin. Avoid if sensitive to gluten~0.3–0.5%
Magnesium aspartateKey activeEffect: MediumMight be helpful in restoring skin barrier function and calm down inflammation in skin~0.3–0.5%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.3–0.6%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.35–0.6%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.3–0.55%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.35–0.65%
C13-14 isoparaffin· EmollientEffect: LowHelps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency~0.3–0.6%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.5%
Copper gluconateUnder-dosedEffect: HighTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.3–0.5%
Anti-oxidation
Not advertised by the brand · Thioctic acid, Pyridoxine hcl + 4 more
Strong evidence

This product contains antioxidants (thioctic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Thioctic acidKey activeEffect: High~0.3–0.55%
Pyridoxine hclEffect: LowMight help neutralize free radicals in skin~0.3–0.5%
Zinc gluconateEffect: LowTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.3–0.5%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.3–0.55%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.3–0.5%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.3–0.55%
Exfoliation
Not advertised by the brand · Glycolic acid, Urea + 2 more
Strong evidence

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%
UreaKey activeEffect: MediumNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.25–0.45%
Zinc gluconateEffect: LowTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.3–0.5%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.3–0.5%
Anti-aging
Not advertised by the brand · Glycolic acid, Zinc gluconate + 3 more
Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains glycolic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%
Zinc gluconateEffect: LowTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.3–0.5%
Thioctic acidEffect: Low~0.3–0.55%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.3–0.55%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.3–0.5%
Evens skin tone
Not advertised by the brand · Glycolic acid, Zinc gluconate + 2 more
Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: zinc gluconate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%
Zinc gluconateEffect: LowTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.3–0.5%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.3–0.55%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.3–0.5%

Can it cause trouble?

Irritancy
13 strong irritants: Benzophenone-4, Methylchloroisothiazolinone + 11 more — patch-test recommended
High risk
We flagged 36 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Sodium laureth sulfateWorks as a foaming cleansing agentHigh~9.3–11.4%est.
Cocamidopropyl betaineHelps water and oil mix together. Used as a cleansing ingredient. Could be an allergenHigh~4.5–5.4%est.
Benzophenone-4Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritatingHigh~0.7–1.05%est.
MethylchloroisothiazolinoneA preservative. Is a frequent allergen in cosmeticsHigh~0.00075–0.0015%est.
MethylisothiazolinoneA preservative. Is a frequent allergenHigh~0.00075–0.0015%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.4–0.6%est.
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.25–0.5%est.
Zinc sulfateA preservative. It can be irritatingHigh~0.3–0.55%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.25–0.5%est.
CitronellolA fragrance. Can be irritatingHigh~0.25–0.5%est.
GeraniolA fragrance. Can be irritatingHigh~0.25–0.5%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.25–0.5%est.
LinaloolA fragrance. Can be irritatingHigh~0.25–0.5%est.
HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.1–0.25%est.
Butylphenyl methylpropionalA fragrance. Can trigger allergic reactions and be irritatingHigh~0.1–0.2%est.
Benzyl benzoateFragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritatingHigh~0.05–0.1%est.
EugenolA fragrance. Is a likely irritantHigh~0.05–0.1%est.
Lauryl glucosideHelps oil and water mix togetherMedium~5–6.2%est.
Zinc gluconateTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skinMedium~1.1–1.4%est.
Copper gluconateTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missingMedium~0.9–1.1%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.65–1%est.
Disodium edtaStabilizes the product formulationMedium~0.5–0.75%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.3–0.55%est.
PhosphatidylcholineUsed to enhance the delivery of other ingredientsMedium~0.25–0.5%est.
Pyridoxine hclMight help neutralize free radicals in skinMedium~0.3–0.5%est.
BhtA preservativeMedium~0.3–0.5%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.4–0.65%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.6%est.
Sorbic acidA preservativeMedium~0.3–0.55%est.
PolyacrylamideUsed to improve product texture and help oil and water mix togetherMedium~0.3–0.6%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.3–0.6%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.3–0.55%est.
Hydrolyzed wheat proteinCan help attract water to the upper layer of the skin. Avoid if sensitive to glutenMedium~0.3–0.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.55%est.
Laureth-7Helps oil and water mix togetherMedium~0.25–0.45%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.2–0.4%est.
Comedogenic
6 ingredients rated 2 or more on the 0–5 pore-clogging scale
6 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.3–0.55%est.
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.3–0.6%est.
Sodium laureth sulfateWorks as a foaming cleansing agent2/5~9.3–11.4%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.6%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.4–0.65%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.35–0.6%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Sodium laureth sulfate~9.3–11.4%
Comedogenic 2/5Irritant · high
Irritation risk
High
Comedogenicity
2/5
Works for
Cleansing

Works as a foaming cleansing agent

More about Sodium laureth sulfate
Lauryl glucoside~5–6.2%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Lauryl glucoside
Cocamidopropyl betaine~4.5–5.4%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps water and oil mix together. Used as a cleansing ingredient. Could be an allergen

More about Cocamidopropyl betaine
Ppg-2 hydroxyethyl coco/isostearamide~2.3–2.8%
Formula
Irritation risk
Low
Works for
Cleansing
More about Ppg-2 hydroxyethyl coco/isostearamide
Dimethyl mea~1.9–2.3%
Formula
Irritation risk
Low
More about Dimethyl mea
Thioctic acid~1.5–1.9%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging
More about Thioctic acid
Magnesium aspartate~1.4–1.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

Might be helpful in restoring skin barrier function and calm down inflammation in skin

More about Magnesium aspartate
Zinc gluconate~1.1–1.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingEvens skin toneExfoliationAnti-inflammatoryAnti-blemishAnti-oxidationAnti-aging

Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin

More about Zinc gluconate
Copper gluconate~0.9–1.1%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-agingEvens skin toneAnti-blemishExfoliation

Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing

More about Copper gluconate
Citric acid~0.65–1%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium chloride~0.65–0.95%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Disodium edta~0.5–0.75%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Benzophenone-4~0.7–1.05%
Irritant · high
Irritation risk
High
Works for
Sun protection

Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating

More about Benzophenone-4
Methylchloroisothiazolinone~0.00075–0.0015%
Irritant · high
Irritation risk
High

A preservative. Is a frequent allergen in cosmetics

More about Methylchloroisothiazolinone
Methylisothiazolinone~0.00075–0.0015%
Irritant · high
Irritation risk
High

A preservative. Is a frequent allergen

More about Methylisothiazolinone
Parfum~0.4–0.6%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Water~0.35–0.65%
Formula
Irritation risk
Low

Plain old water

More about Water
Dimethyl mea~0.3–0.6%
Formula
Irritation risk
Low
More about Dimethyl mea
Thioctic acid~0.3–0.55%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging
More about Thioctic acid
Isopropyl palmitate~0.3–0.55%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Cetearyl alcohol~0.3–0.6%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Tyrosine~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Glycolic acid~0.25–0.5%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid
Dimethyl isosorbide~0.25–0.5%
Formula
Irritation risk
Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide
Propanediol~0.3–0.5%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~0.35–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Urea~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Phosphatidylcholine~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to enhance the delivery of other ingredients

More about Phosphatidylcholine
Xanthan gum~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Magnesium aspartate~0.3–0.5%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Might be helpful in restoring skin barrier function and calm down inflammation in skin

More about Magnesium aspartate
Zinc gluconate~0.3–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationExfoliationEvens skin toneAnti-inflammatoryAnti-agingAnti-blemish

Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin

More about Zinc gluconate
Acetyl tyrosine~0.3–0.5%
Formula
Irritation risk
Low
More about Acetyl tyrosine
Pyridoxine hcl~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Might help neutralize free radicals in skin

More about Pyridoxine hcl
Copper gluconate~0.3–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-agingAnti-oxidationExfoliationAnti-blemishEvens skin tone

Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing

More about Copper gluconate
Sodium hyaluronate~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Bht~0.3–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Disodium edta~0.3–0.55%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ceteareth-20~0.4–0.65%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Ammonium acryloyldimethyltaurate/vp copolymer~0.3–0.55%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Dimethicone~0.35–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Caprylyl glycol~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Zinc sulfate~0.3–0.55%
Irritant · high
Irritation risk
High

A preservative. It can be irritating

More about Zinc sulfate
Phenoxyethanol~0.3–0.55%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sorbic acid~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Parfum~0.25–0.5%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Citral~0.25–0.5%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Citronellol~0.25–0.5%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Geraniol~0.25–0.5%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Limonene~0.25–0.5%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.25–0.5%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Water~0.3–0.55%
Formula
Irritation risk
Low

Plain old water

More about Water
Ethylhexyl palmitate~0.3–0.6%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Glycerin~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Aleurites moluccanus seed oil~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Aleurites moluccanus seed oil
Polyacrylamide~0.3–0.6%
Irritant · medium
Irritation risk
Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide
Cetearyl alcohol~0.35–0.6%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
C13-14 isoparaffin~0.3–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Polysorbate 60~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Glyceryl stearate~0.35–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~0.4–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Dimethyl mea~0.3–0.55%
Formula
Irritation risk
Low
More about Dimethyl mea
Tetrahexyldecyl ascorbate~0.3–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-agingEvens skin tone

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate
Tyrosine~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Tyrosine
Hydrolyzed wheat protein~0.3–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten

More about Hydrolyzed wheat protein
Tocopheryl acetate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Hydrolyzed wheat starch~0.25–0.5%
Formula
Irritation risk
Low
More about Hydrolyzed wheat starch
Citric acid~0.25–0.5%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Peg/ppg-18/18 dimethicone~0.3–0.55%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A silicone that mixes with water creating nice light-weight product texture

More about Peg/ppg-18/18 dimethicone
Dimethicone~0.3–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Caprylyl glycol~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Laureth-7~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Hexylene glycol~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Phenoxyethanol~0.2–0.35%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Parfum~0.15–0.25%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Citronellol~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Geraniol~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Hydroxycitronellal~0.1–0.25%
Irritant · high
Irritation risk
High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal
Butylphenyl methylpropional~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can trigger allergic reactions and be irritating

More about Butylphenyl methylpropional
Benzyl benzoate~0.05–0.1%
Irritant · high
Irritation risk
High

Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating

More about Benzyl benzoate
Eugenol~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Eugenol
Ingredient list view

Water, Sodium laureth sulfate, Lauryl glucoside, Cocamidopropyl betaine, Ppg-2 hydroxyethyl coco/isostearamide, Dimethyl mea, Thioctic acid, Magnesium aspartate, Zinc gluconate, Copper gluconate, Citric acid, Sodium chloride, Disodium edta, Benzophenone-4, Methylchloroisothiazolinone, Methylisothiazolinone, Parfum, Water, Dimethyl mea, Thioctic acid, Isopropyl palmitate, Cetearyl alcohol, Tyrosine, Glycolic acid, Dimethyl isosorbide, Propanediol, Glyceryl stearate, Peg-100 stearate, Urea, Phosphatidylcholine, Xanthan gum, Magnesium aspartate, Zinc gluconate, Acetyl tyrosine, Pyridoxine hcl, Copper gluconate, Sodium hyaluronate, Bht, Disodium edta, Ceteareth-20, Ammonium acryloyldimethyltaurate/vp copolymer, Dimethicone, Caprylyl glycol, Zinc sulfate, Phenoxyethanol, Sorbic acid, Parfum, Citral, Citronellol, Geraniol, Limonene, Linalool, Water, Ethylhexyl palmitate, Glycerin, Aleurites moluccanus seed oil, Polyacrylamide, Cetearyl alcohol, C13-14 isoparaffin, Polysorbate 60, Glyceryl stearate, Peg-100 stearate, Dimethyl mea, Tetrahexyldecyl ascorbate, Tyrosine, Hydrolyzed wheat protein, Tocopheryl acetate, Hydrolyzed wheat starch, Citric acid, Peg/ppg-18/18 dimethicone, Dimethicone, Caprylyl glycol, Laureth-7, Hexylene glycol, Phenoxyethanol, Parfum, Citronellol, Geraniol, Hydroxycitronellal, Butylphenyl methylpropional, Benzyl benzoate, Eugenol

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Perricone MD
$149.00
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Product summary

Based on the ingredients included, "Perricone MD - Classic Firming Regimen" works well for moisturizing the skin. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Urea, glycerin, sodium hyaluronate, hydrolyzed wheat protein and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Dimethicone, cetearyl alcohol, ethylhexyl palmitate, c13-14 isoparaffin and caprylyl glycol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.

Price

The product retails for 149.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

  1. 1
    Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
  2. 2
    Magnesium ions inhibit the antigen-presenting function of human epidermal Langerhans cells in vivo and in vitro. Involvement of ATPase, HLA-DR, B7 molecules, and cytokinesncbi.nlm.nih.gov
  3. 3
    Zinc salts in dermatologyncbi.nlm.nih.gov
  4. 4
    An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disordersoatext.com
  5. 5
    Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrinsncbi.nlm.nih.gov
  6. 6
    Evaluation of the effects of topical zinc gluconate in wound healingncbi.nlm.nih.gov
Perricone MD Classic Firming Regimen
Perricone MDClassic Firming Regimen
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