Works for:
based on ingredients and %- Moisturizing
- Anti-oxidation
- Evens skin tone
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 2
Key actives
Product Summary
Based on the ingredients included, "SkinMedica - GlyPro Renewal Cream" works well for moisturizing the skin. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (urea, algae extract, glycerin, saccharide isomerate and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (algae extract, caprylic/capric triglyceride, cetearyl alcohol, cyclopentasiloxane and caprylyl glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- We like that this moisturizer contains peptides (dipeptide diaminobutyroyl benzylamide diacetate 0.35% - 0.60%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 84.60$ in the United States.
For a detailed price comparison: click here.
Works for
Anti-oxidation
This product contains antioxidants (superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
A derivative of vitamin C that is more stable, but less bioavailable than the pure form of vitamin C. It does not penetrate the skin well, but has been shown to convert to pure vitamin C once in skin. It can be helpful in stimulating collagen production and lightening the skin tone, but the required concentration is likely to be very high
Moisturizing
What does the product description say?
An ultra-rich cream utilizing powerful antioxidants and glycolic acid to help retain moisture and encourage skin renewal and softness.
Source: Skinstore
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
algae extract, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, algae extract.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: dipeptide diaminobutyroyl benzylamide diacetate, urea
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps attract water to the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Naturally present in skin and helps to attract water to its upper layer
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
A sugar that attracts water to the upper layer of the skin
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
An emollient that helps create a nice silky finish on the skin
Helps preserve products and creates a nice product texture
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation
Used to preserve products, dissolve other ingredients and create a nice product texture
A silicone that serves as an emollient. Helps create a nice non-greasy feels
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Helps oil and water mix together and works as an emollient
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 SkinMedica GlyPro Renewal Cream | Current | $84.60 | |
dreveryouth Vitamin C + Hyaluronic Acid Hydrabright Night Moisturiser | 47% | $65.00 | |
 Dr. Eve_Ryouth Snake Venom + Collagen Wrinkle Filler Night Moisturiser | 47% | $65.00 | |
PRIORI Skincare Q+SOD fx240 Moisturising Crème | 47% | $48.62 | |
 M-61 JetGlow Cream | 46% | - | |
 Revaleskin Night Cream | 45% | $132.00 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Glycolic acid, Cyclopentasiloxane, Glycerin, Bis-hydroxyethoxypropyl dimethicone, Cetearyl alcohol, Stearyl alcohol, Pentylene glycol, Caprylic/capric triglyceride, Ceresin, Saccharide isomerate, Cyclohexasiloxane, Cetearyl glucoside, Dipeptide diaminobutyroyl benzylamide diacetate, Algae extract, Glyceryl stearate, Peg-100 stearate, Octyldodecanol, Irvingia gabonensis kernel butter, Hydrogenated coco-glycerides, Magnesium aluminum silicate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Stearic acid, Sodium pca, Urea, Trehalose, Polyquaternium-51, Sodium hyaluronate, Hydroxyethylcellulose, Dimethicone crosspolymer, Olea europaea leaf extract, Superoxide dismutase, Magnesium ascorbyl phosphate, Tocopherol, Hexylene glycol, Caprylyl glycol, Triacetin, Aluminum hydroxide, Ammonium hydroxide, Disodium edta, Ethylhexylglycerin, Phenoxyethanol, Potassium sorbate, Titanium dioxide, Ci 77891
- Photoprotective and antiinflammatory effects of topical glycolic acid
- Glycolic acid peel therapy – a current review
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Glycerol and the skin: holistic approach to its origin and functions
- Final report on the safety assessment of aluminum silicate, calcium silicate, magnesium aluminum silicate, magnesium silicate, magnesium trisilicate, sodium magnesium silicate, zirconium silicate, attapulgite, bentonite, Fuller's earth, hectorite, kaolin, lithium magnesium silicate, lithium magnesium sodium silicate, montmorillonite, pyrophyllite, and zeolite
- Extracellular matrix in cutaneous ageing: the effects of 0.1% copper-zinc malonate-containing cream on elastin biosynthesis
- Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmetics
- Topical urea in skincare: A review
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Wound Repair Potential of Olea europaea L. Leaf Extracts Revealed by In Vivo Experimental Models and Comparative Evaluation of the Extracts' Antioxidant Activity
- A novel efficient and safe treatment for atopic dermatitis: Topical superoxide dismutase (SOD).
- Novel topical agent containing superoxide dismutase 100 000 IU and 4% of plant extracts as a mono-therapy for atopic dermatitis
- Copper/Zinc Superoxide Dismutase in Human Skin: Current Knowledge
- Photoprotective Effect of Topically Applied Superoxide Dismutase on Sunburn Reaction in Comparison with Sunscreen
- The role of superoxide dismutase (SOD) in skin disorders
- Topical formulations with superoxide dismutase: Influence of formulation composition on physical stability and enzymatic activity
- Skin protective effects of RM191A, a novel superoxide dismutase mimetic
- Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives
- Topical L-ascorbic acid: percutaneous absorption studies
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Final report on the safety assessment of triacetin
- Safety Assessment of Alumina and Aluminum Hydroxide as Used in Cosmetics