Dupes & alternatives for La Roche-Posay-Substiane Serum

Substiane Serum
La Roche-Posay

Substiane Serum

Medium irritancy Score: 87/100
20 alternatives found · Best match: 60% (Medium)
Laboratories Firming Booster Serum
$34.95
Low irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERINSODIUM HYALURONATE +2 more

Key differences

PALMITOYL TRIPEPTIDE-1PALMITOYL TETRAPEPTIDE-7HYDROLYZED HYALURONIC ACID +1 more
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Similarity breakdown
Overall formula60%
Hero ingredients100%
Active ingredients83%
All ingredients31%
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& Lipopeptide Serum
Triple Hyaluronic Acid
& Lipopeptide Serum
57%
Medium match
$60.00
Low irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERINSODIUM HYALURONATE

Key differences

ANHYDROXYLITOLCHONDRUS CRISPUS EXTRACTHYALURONIC ACID +4 more
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FirmX Growth Factor Neuropeptide Serum
55%
Medium match
$150.00
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERDIMETHICONEDIMETHICONOL +2 more

Key differences

RETINYL PALMITATEUREAPALMITOYL HEXAPEPTIDE-19 +10 more
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Serum No.10 Eye Contour Anti-Aging and Energy Serum
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERSODIUM HYALURONATEDIMETHICONOL +1 more

Key differences

SALICYLIC ACIDACETYL TETRAPEPTIDE-5ACETYL HEXAPEPTIDE-37 +18 more
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Fast Fix Chin Tuck V Shape Lifting Serum
$88.00
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERDIMETHICONEGLYCERIN +1 more

Key differences

NIACINAMIDEBETAINECAFFEINE +4 more
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Similarity breakdown
Overall formula54%
Hero ingredients100%
Active ingredients67%
All ingredients29%
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Hydrotenseur serum
52%
Medium match
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERSODIUM HYALURONATEGLYCERIN

Key differences

LACTOBIONIC ACIDCERAMIDE NPCERAMIDE AP +9 more
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Skintelligence Hydra Hydrating Serum
$15.95
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERINSODIUM HYALURONATE

Key differences

ALPHA-GLUCAN OLIGOSACCHARIDELACTOBACILLUSSODIUM POLYACRYLATE
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Similarity breakdown
Overall formula51%
Hero ingredients100%
Active ingredients50%
All ingredients23%
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NB Ceutical Intensive Tolerance Booster
50%
Medium match
$250.00
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERSERINEGLYCERIN

Key differences

TRIPEPTIDE-1UREAPANTHENOL +7 more
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Similarity breakdown
Overall formula50%
Hero ingredients100%
Active ingredients50%
All ingredients31%
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ELEVATE Firming & Lifting Contouring Serum
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERIN

Key differences

ARGININE/LYSINE POLYPEPTIDEACETYL TETRAPEPTIDE-2ADENOSINE +10 more
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s Skin Rescuer Stress-Minimizing Daily Hydrator
$25.20
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERIN

Key differences

HYDROXYPALMITOYL SPHINGANINECAPROOYL SPHINGOSINECERAMIDE AP +10 more
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Tightening Neck Serum Roller New
44%
Medium match
$59.25
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERDIMETHICONEGLYCERIN +1 more

Key differences

PALMITOYL TRIPEPTIDE-1JOJOBA ESTERSALGAE EXTRACT +3 more
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Similarity breakdown
Overall formula44%
Hero ingredients100%
Active ingredients67%
All ingredients29%
View full product details
Ultimate Miracle Worker Fix Facial Serum Roller Uplift & Firm
$78.00
High irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERDIMETHICONEGLYCERIN

Key differences

RETINOLGLYCOLIC ACIDADENOSINE +8 more
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Power Serum
HydroPeptide
Power Serum
42%
Medium match
$93.00
High irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERINSODIUM HYALURONATE

Key differences

ACETYL HEXAPEPTIDE-30HEXAPEPTIDE-11PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINE +7 more
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40% Collagen Peptide Plumping Serum
41%
Medium match
$33.00
High irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERSODIUM HYALURONATEGLYCERIN

Key differences

ACETYL HEXAPEPTIDE-1NIACINAMIDEADENOSINE +13 more
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Superdrug Simply Pure Hydrating Night Serum
$3.99
Low irritancy

Why it matches

DIMETHICONEDIMETHICONOLGLYCERIN +2 more

Key differences

UREAHYALURONIC ACIDCAPRYLIC/CAPRIC TRIGLYCERIDE +2 more
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Similarity breakdown
Overall formula41%
Active ingredients83%
All ingredients40%
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Ageless Genius Firming & Wrinkle Smoothing Serum
$40.00
High irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERDIMETHICONEGLYCERIN

Key differences

ARGININE/LYSINE POLYPEPTIDERETINYL PALMITATEPALMITOYL TETRAPEPTIDE-7 +6 more
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Neck Elasticity Catalyst Serum
40%
Medium match
$40.00
Medium irritancy

Why it matches

ACETYL DIPEPTIDE-1 CETYL ESTERGLYCERIN

Key differences

ACETYL CYCLOHEXAPEPTIDE-34ACETYL TETRAPEPTIDE-2UREA +9 more
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About Similarity Scores

Our similarity score compares product formulas based on shared active ingredients, hero ingredients, and overall formula composition. A higher score means a more similar formula.

70%+ - High match
40-69% - Medium match
<40% - Low match

Note: Similarity is based on WIMJ's formula analysis (actives + overall formula similarity). Ingredient concentrations are estimated; products aren't lab-tested. A similar formula doesn't guarantee the same texture or feel.