Filorga

Filorga Time-Zero Serum

Name: Filorga - Time-Zero Serum
Brand: Filorga

Efficacy58/100IrritancyMedium

See all ingredients

Works for

Moisturizing

Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 + 45 more

Works well

What the product description says

“Utilising three varieties of Hyaluronic Acid, the formula works to visibly plump the complexion and fill deep-set wrinkles, whilst Matrikines and NCTF (Filorga’s exclusive complex) tackle lines that are a result of fatigue.”

Source: Mankind

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, aminobutyric acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.8–5.9%

Hydrolyzed yeast extractKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~3.8–4.6%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~3.1–3.7%

C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~2.3–2.8%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.6–2%

Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.4–1.8%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.2–1.5%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.6%

HydroxyprolineKey activeEffect: HighIs helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking~0.2–0.35%

InositolKey active· HumectantEffect: High~0.2–0.35%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

TyrosineKey activeEffect: High~0.2–0.35%

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.2–0.35%

Aminobutyric acidKey active· HumectantEffect: HighHas been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing~0.2–0.35%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.2–0.35%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.2–0.35%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.2–0.35%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.2–0.35%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.2–0.35%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.2–0.35%

HistidineKey active· HumectantEffect: High~0.2–0.35%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.2–0.35%

Lysine hclKey activeEffect: High~0.2–0.35%

OrnithineKey activeEffect: HighAn amino-acid. Helps attract water to the upper layer of the skin~0.2–0.35%

Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~0.2–0.35%

Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.2–0.35%

ProlineKey activeEffect: Medium~0.2–0.4%

TrihydroxystearinKey activeEffect: MediumHelps soften the upper layer of the skin and improve the product texture~0.15–0.3%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.15–0.3%

Crithmum maritimum extractKey activeEffect: MediumAn algae extract that might have anti-oxidant properties~0.15–0.25%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.8–1.2%

Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.3–0.55%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.35%

Coenzyme aEffect: LowHelps soften the upper layer of the skin and dissolve other ingredients in a product~0.2–0.35%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.1–0.2%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.35%

GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.6–0.9%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.4–0.6%

NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.15–0.3%

NiacinUnder-dosedA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.15–0.3%

AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.25%

Anti-aging

Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 + 15 more

May help

What the product description says

“Tackle wrinkles with the Filorga Time-Zero Serum ; a potent formula that works to visibly correct all types of wrinkles, including the most stubborn lines.”

Source: Mankind

This product contains acetyl hexapeptide-8, aspartic acid, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, retinyl acetate, serine, threonine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.2–0.35%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

Retinyl acetateKey activeEffect: Medium~0.2–0.35%

Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.6–2%

Aminobutyric acidEffect: LowHas been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing~0.2–0.35%

HydroxyprolineEffect: LowIs helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking~0.2–0.35%

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.2–0.35%

Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.15–0.3%

NiacinUnder-dosedA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.15–0.3%

Exfoliation

Gluconolactone ~0.6–0.9%, below the ~1% it needs

Under-dosed

What the product description says

“Providing exfoliation, Gluconolactone resurfaces the skin and visibly fades fine lines on its surface.”

Source: Mankind

This product does not contain effective exfoliating ingredients. It might be able to deliver physical exfoliation, that is scrub off some of the dead cells on the surface of the skin. We do not recommend physical exfoliation, because it is not uniform (some bits of skin can get exfoliated too much while others not at all). It can also traumatize the skin and aggrevate acne and other skin conditions.

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.25%

Anti-oxidation

Side benefit · Glutathione, Hydrolyzed yeast extract + 8 more

Works well

This product contains antioxidants (glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Hydrolyzed yeast extractEffect: LowHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~3.8–4.6%

TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.2–0.35%

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.2–0.35%

Pyridoxine hclEffect: LowMight help neutralize free radicals in skin~0.15–0.3%

Crithmum maritimum extractEffect: LowAn algae extract that might have anti-oxidant properties~0.15–0.25%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%

Evens skin tone

Side benefit · Glutathione, Hydrolyzed yeast extract + 6 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Hydrolyzed yeast extractEffect: LowHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~3.8–4.6%

AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.2–0.35%

TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.2–0.35%

NiacinUnder-dosedA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect~0.15–0.3%

Can it cause trouble?

Irritancy

2 strong irritants: Parfum, Retinyl acetate

Medium risk

We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.3–0.55%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.15–0.3%est.

Retinyl acetate—High~0.2–0.35%est.

NiacinA form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effectHigh~0.15–0.3%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.6–0.9%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.55–0.85%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.4–0.6%est.

EthylhexylglycerinA preservativeMedium~0.25–0.45%est.

Glyceryl linoleateHelps oil and water mix togetherMedium~0.25–0.5%est.

Disodium edtaStabilizes the product formulationMedium~0.15–0.3%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.35%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.

Potassium sorbateA preservativeMedium~0.15–0.3%est.

Calcium chlorideHelps create a thicker product consistency. Might be irritatingMedium~0.15–0.3%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.2–0.35%est.

TaurineCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectivenessMedium~0.2–0.35%est.

Pyridoxine hclMight help neutralize free radicals in skinMedium~0.15–0.3%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~3.1–3.7%est.

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.6–2%est.

Crithmum maritimum extractAn algae extract that might have anti-oxidant properties3/5~0.15–0.25%est.

Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~0.2–0.35%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.8–5.9%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Hydrolyzed yeast extract~3.8–4.6%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties

More about Hydrolyzed yeast extract

Ethylhexyl palmitate~3.1–3.7%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

C12-15 alkyl benzoate~2.3–2.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate

Phenoxyethanol~0.5–1%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Butyrospermum parkii butter~1.6–2%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Cetyl alcohol~1.4–1.8%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol

Dimethicone~1.2–1.5%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Butylene glycol~0.8–1.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Gluconolactone~0.6–0.9%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

ExfoliationMoisturizingAnti-agingEvens skin toneAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Acrylates/c10-30 alkyl acrylate crosspolymer~0.55–0.85%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Sodium acrylate/sodium acryloyldimethyl taurate copolymer~0.5–0.75%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Sodium acrylate/sodium acryloyldimethyl taurate copolymer

Sucrose palmitate~0.45–0.65%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sucrose palmitate

Parfum~0.3–0.55%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Sodium hyaluronate~0.3–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Caprylic/capric triglyceride~0.4–0.6%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Polysorbate 80~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps water and oil mix together

More about Polysorbate 80

Ethylhexylglycerin~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Glyceryl linoleate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Glyceryl linoleate

Isohexadecane~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane

Sodium hydroxide~0.2–0.35%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Allantoin~0.15–0.25%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-blemishReduces irritationReduces rednessExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Prunus amygdalus dulcis oil~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil

Sodium chloride~0.2–0.35%

Formula

Irritation risk: Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride

Xanthan gum~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Disodium edta~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Hydrogenated vegetable oil~0.2–0.35%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil

Cetyl hydroxyethylcellulose~0.2–0.35%

Formula

Irritation risk: Low

Used to create a thicker product consistency and stabilize formulations

More about Cetyl hydroxyethylcellulose

Trihydroxystearin~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and improve the product texture

More about Trihydroxystearin

Carbomer~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Polyglucuronic acid~0.15–0.3%

Formula

Irritation risk: Low

Often used to support the moisturization effect of polysaccharides (contained, for example, in yeast extract)

More about Polyglucuronic acid

Dipeptide diaminobutyroyl benzylamide diacetate~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate

Polysorbate 20~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Caprylyl glycol~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Crithmum maritimum extract~0.15–0.25%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

An algae extract that might have anti-oxidant properties

More about Crithmum maritimum extract

Glucose~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Lecithin~0.2–0.35%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Citric acid~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Potassium chloride~0.15–0.3%

Formula

Irritation risk: Low

More about Potassium chloride

Potassium sorbate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Sodium benzoate~0.15–0.3%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Calcium chloride~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Helps create a thicker product consistency. Might be irritating

More about Calcium chloride

Magnesium sulfate~0.2–0.35%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Magnesium sulfate

Glutamine~0.15–0.3%

Formula

Irritation risk: Low

More about Glutamine

Sodium phosphate~0.15–0.3%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Sodium phosphate

Acetyl hexapeptide-8~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Ascorbic acid~0.15–0.3%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingAnti-oxidationEvens skin tone

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Sodium acetate~0.2–0.35%

Formula

Irritation risk: Low

More about Sodium acetate

Tocopherol~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingMoisturizingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Lysine hcl~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Lysine hcl

Arginine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Palmitoyl tripeptide-1~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Alanine~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Histidine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Histidine

Valine~0.2–0.35%

Formula

Irritation risk: Low

More about Valine

Palmitoyl tetrapeptide-7~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Leucine~0.2–0.35%

Formula

Irritation risk: Low

More about Leucine

Threonine~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Isoleucine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Tryptophan~0.2–0.35%

Formula

Irritation risk: Low

More about Tryptophan

Phenylalanine~0.2–0.35%

Formula

Irritation risk: Low

More about Phenylalanine

Tyrosine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Glycine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Glucomannan~0.2–0.35%

Formula

Irritation risk: Low

More about Glucomannan

Serine~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

2'-deoxyadenosine~0.15–0.3%

Formula

Irritation risk: Low

More about 2'-deoxyadenosine

Cystine~0.2–0.35%

Formula

Irritation risk: Low

More about Cystine

Cyanocobalamin~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Deoxycytidine~0.15–0.3%

Formula

Irritation risk: Low

More about Deoxycytidine

Deoxyguanosine~0.15–0.3%

Formula

Irritation risk: Low

More about Deoxyguanosine

Thymidine~0.2–0.35%

Formula

Irritation risk: Low

More about Thymidine

Glutathione~0.2–0.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Asparagine~0.2–0.35%

Formula

Irritation risk: Low

More about Asparagine

Aspartic acid~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Ornithine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid. Helps attract water to the upper layer of the skin

More about Ornithine

Glutamic acid~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Nicotinamide adenine dinucleotide~0.2–0.35%

Formula

Irritation risk: Low

More about Nicotinamide adenine dinucleotide

Proline~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Aminobutyric acid~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-agingAnti-inflammatory

Has been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing

More about Aminobutyric acid

Methionine~0.2–0.35%

Formula

Irritation risk: Low

More about Methionine

Taurine~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Anti-inflammatoryAnti-oxidationAnti-blemishEvens skin tone

Could be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness

More about Taurine

Hydroxyproline~0.2–0.35%

Key active

Irritation risk: Low

Works for

CleansingMoisturizingAnti-aging

Is helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking

More about Hydroxyproline

Glucosamine~0.2–0.35%

Formula

Irritation risk: Low

More about Glucosamine

Coenzyme a~0.2–0.35%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and dissolve other ingredients in a product

More about Coenzyme a

Glucuronolactone~0.2–0.4%

Formula

Irritation risk: Low

More about Glucuronolactone

Sodium glucuronate~0.2–0.35%

Formula

Irritation risk: Low

More about Sodium glucuronate

Thiamine diphosphate~0.2–0.4%

Formula

Irritation risk: Low

More about Thiamine diphosphate

Sodium uridine triphosphate

Not recognized

Disodium flavine adenine dinucleotide~0.2–0.35%

Formula

Irritation risk: Low

More about Disodium flavine adenine dinucleotide

Retinyl acetate~0.2–0.35%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-aging

More about Retinyl acetate

Inositol~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Inositol

Methyl deoxycytidine

Not recognized

Niacin~0.15–0.3%

Under-dosedIrritant · high

Irritation risk: High

Works for

MoisturizingEvens skin toneAnti-agingAnti-blemish

A form of vitamin B3. It is similar in action to niacinamide, but is more likely to cause red flashes in skin as the side effect

More about Niacin

Niacinamide~0.15–0.3%

Under-dosed

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Pyridoxal 5-phosphate~0.15–0.3%

Formula

Irritation risk: Low

More about Pyridoxal 5-phosphate

Pyridoxine hcl~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

Might help neutralize free radicals in skin

More about Pyridoxine hcl

Biotin~0.1–0.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Not recognized

Ingredient list view

Water, Glycerin, Hydrolyzed yeast extract, Ethylhexyl palmitate, C12-15 alkyl benzoate, Phenoxyethanol, Butyrospermum parkii butter, Cetyl alcohol, Dimethicone, Butylene glycol, Gluconolactone, Acrylates/c10-30 alkyl acrylate crosspolymer, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Sucrose palmitate, Parfum, Sodium hyaluronate, Caprylic/capric triglyceride, Polysorbate 80, Ethylhexylglycerin, Glyceryl linoleate, Isohexadecane, Sodium hydroxide, Allantoin, Prunus amygdalus dulcis oil, Sodium chloride, Xanthan gum, Disodium edta, Hydrogenated vegetable oil, Cetyl hydroxyethylcellulose, Trihydroxystearin, Carbomer, Polyglucuronic acid, Dipeptide diaminobutyroyl benzylamide diacetate, Polysorbate 20, Caprylyl glycol, Crithmum maritimum extract, Glucose, Lecithin, Citric acid, Potassium chloride, Potassium sorbate, Sodium benzoate, Calcium chloride, Magnesium sulfate, Glutamine, Sodium phosphate, Acetyl hexapeptide-8, Ascorbic acid, Sodium acetate, Tocopherol, Lysine hcl, Arginine, Palmitoyl tripeptide-1, Alanine, Histidine, Valine, Palmitoyl tetrapeptide-7, Leucine, Threonine, Isoleucine, Tryptophan, Phenylalanine, Tyrosine, Glycine, Glucomannan, Serine, 2'-deoxyadenosine, Cystine, Cyanocobalamin, Deoxycytidine, Deoxyguanosine, Thymidine, Glutathione, Asparagine, Aspartic acid, Ornithine, Glutamic acid, Nicotinamide adenine dinucleotide, Proline, Aminobutyric acid, Methionine, Taurine, Hydroxyproline, Glucosamine, Coenzyme a, Glucuronolactone, Sodium glucuronate, Thiamine diphosphate, Unknown, Disodium flavine adenine dinucleotide, Retinyl acetate, Inositol, Unknown, Niacin, Niacinamide, Pyridoxal 5-phosphate, Pyridoxine hcl, Biotin, Unknown

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	FilorgaTime-Zero SerumYOUR PRODUCT	ArenciaDeep Water Surge Serum 30	Bliv:UCollagen Bouncing Serum Pad	NIDASalmon PDRN Peptide Serum
Match	—	78%	78%	77%
Price	—	$15.74	$19.61	$13.32
Shared key ingredients	—	17 of 32	17 of 32	7 of 32
Key difference	—	Copper Tripeptide-1	Hexapeptide-9	Copper Tripeptide-1
Irritancy	Medium	Medium	Medium	Low
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 47 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transferncbi.nlm.nih.gov
3
Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitaminsresearchgate.net
4
Dimethicone as a protective ingredient in topical medicationsjaad.org
5
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
6
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acnencbi.nlm.nih.gov
7
The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoagingonlinelibrary.wiley.com
8
Applications of hydroxy acids: classification, mechanisms, and photoactivityncbi.nlm.nih.gov
9
The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative studydovepress.com
10
A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimenncbi.nlm.nih.gov
11
The use of polyhydroxy acids (PHAs) in photoaged skin
12
Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acidsonlinelibrary.wiley.com
13
An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patientsonlinelibrary.wiley.com
14
Aging Skin: Causes, Treatments, and Preventionsciencedirect.com
15
Clinical and cosmeceutical uses of hydroxyacidssciencedirect.com
16
Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Lightneostrata.neogen.gr
17
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
18
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
19
Profile of wound healing process induced by allantoinscielo.br
20
Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oilsmdpi.com
21
Polyglucuronic acids: Structures, functions and degrading enzymessciencedirect.com
22
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Functionncbi.nlm.nih.gov
23
Safety Assessment of Magnesium Sulfate as Used in Cosmeticsncbi.nlm.nih.gov
24
Vitamin E in dermatologyncbi.nlm.nih.gov
25
Vitamin E and Skin Healthlpi.oregonstate.edu
26
Combination of amino acids reduces pigmentation in B16F0 melanoma cellsncbi.nlm.nih.gov
27
Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseasespatents.google.com
28
Safety Assessment of α-Amino Acids as Used in Cosmeticsciteseerx.ist.psu.edu
29
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
30
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trialonlinelibrary.wiley.com
31
Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiencyjamanetwork.com
32
Functional glycine receptor in cultured human keratinocytesonlinelibrary.wiley.com
33
Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trialpubmed.ncbi.nlm.nih.gov
34
Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasisncbi.nlm.nih.gov
35
Glutathione as a skin whitening agent: Facts, myths, evidence and controversiesijdvl.com
36
Glutathione for skin lightening: a regnant myth or evidence-based verity?ncbi.nlm.nih.gov
37
Glutathione for skin lightening for dermatologists and cosmetologistsijord.com
38
Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proofncbi.nlm.nih.gov
39
In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmnessncbi.nlm.nih.gov
40
gamma-Aminobutyric acid (A) receptor agonists accelerate cutaneous barrier recovery and prevent epidermal hyperplasia induced by barrier disruptionpubmed.ncbi.nlm.nih.gov
41
Wound healing activity of gamma-aminobutyric Acid (GABA) in ratspubmed.ncbi.nlm.nih.gov
42
Moisturizing effect of Gamma-aminobutyric acid for cosmetic applicationam-2017.weebly.com
43
Stimulation of human fibroblast collagen synthesis in vitro by gamma-aminobutyric acidpubmed.ncbi.nlm.nih.gov
44
Cosmeceuttical Critigue: Taurinemdedge.com
45
Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritusncbi.nlm.nih.gov
46
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
47
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov

FilorgaTime-Zero Serum

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