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Product summary

Judging from the ingredient list, "Derm Institute - Anti-Oxidant Hydration Cream" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Derm Institute - Anti-Oxidant Hydration Cream ticks this box. Algae extract, glycerin, hyaluronic acid, saccharide isomerate and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide 1, ceramide 3, ceramide 6 ii, palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1 in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • As a plus, this moisturizer also contains ceramides (ceramide 1 0.15% - 0.25%, ceramide 6 ii 0.25% - 0.50%, phytosphingosine 0.25% - 0.50% and ceramide 3 0.30% - 0.55%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • This moistruizer also contains peptides (palmitoyl tripeptide-5 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55%, palmitoyl tetrapeptide-7 0.30% - 0.55% and palmitoyl oligopeptide 0.35% - 0.60%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.


The product retails from 125.00£ up to 150.00£ in the United Kingdom and for 150.00$ in the United States.

For a detailed price comparison: click here.