Product summary
Judging from the ingredient list, "Derm Institute - Anti-Oxidant Hydration Cream" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Derm Institute - Anti-Oxidant Hydration Cream ticks this box. Algae extract, glycerin, hyaluronic acid, saccharide isomerate and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide 1, ceramide 3, ceramide 6 ii, palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1 in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- As a plus, this moisturizer also contains ceramides (ceramide 1 0.15% - 0.25%, ceramide 6 ii 0.25% - 0.50%, phytosphingosine 0.25% - 0.50% and ceramide 3 0.30% - 0.55%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- This moistruizer also contains peptides (palmitoyl tripeptide-5 0.25% - 0.45%, palmitoyl tripeptide-1 0.30% - 0.55%, palmitoyl tetrapeptide-7 0.30% - 0.55% and palmitoyl oligopeptide 0.35% - 0.60%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 125.00£ up to 150.00£ in the United Kingdom and for 150.00$ in the United States.
For a detailed price comparison: click here.
Benefits
Promise: Anti-aging
What does the product description say?
Protect the skin from environmental damage with the Derm Institute Anti-Oxidant Hydration Cream, a nourishing skincare treatment that promotes elasticity and works to restore the skin’s natural balance.
This product contains adenosine triphosphate, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, resveratrol. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
adenosine triphosphate | MEDIUM | ||
palmitoyl oligopeptide | MEDIUM | ||
palmitoyl tetrapeptide-7 | MEDIUM |
Promise: Moisturizing
What does the product description say?
Anti-Oxidant Hydration Cream
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
algae extract, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, algae extract.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 1, ceramide 3, ceramide 6 ii, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, phytosphingosine
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
algae extract | HIGH | ||
caprylic/capric triglyceride | HIGH | ||
ceramide 1 | HIGH |
Other benefit: Anti-oxidation
This product contains antioxidants (resveratrol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
resveratrol | HIGH | ||
corallina officinalis extract | LOW | ||
pyridoxine hcl | LOW |
Honesty check
How honest is this product?
Promise | Can it deliver? |
---|---|
Moisturizing | |
Anti-aging |
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Potential irritants

Ingredient | Irritancy | Skin Benefit |
---|---|---|
propylene glycol | ||
melia azadirachta leaf extract | ||
chamomilla recutita flower extract |
User reviews (0)
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WIMJ similarity score | 72% | 70% | 70% | 70% | 69% | 68% | 68% | 68% | 68% | 68% | |
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Ingredients & concentrations
- niacinamide
- lactic acid
- palmitoyl tetrapeptide-7
- palmitoyl tripeptide-1
- palmitoyl tripeptide-5
- panthenol
- phytosphingosine
- ceramide 6 ii
- ceramide 1
- ceramide 3
- palmitoyl oligopeptide
- hyaluronic acid
- hydroxyproline
- melia azadirachta leaf extract
- resveratrol
- saccharide isomerate
- Jojoba oil
- adenosine triphosphate
- sodium hyaluronate
- algae extract
- allantoin
- bisabolol
- camellia sinensis leaf extract
- caprylic/capric triglyceride
- cholesterol
- corallina officinalis extract
- cyclopentasiloxane
- ergothioneine
- glycerin
- +25 more
Ingredient | Estimated concentration |
---|---|
45% - 55% | |
Plain old water | |
6.1% - 7.5% | |
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin | |
4.5% - 5.5% | |
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin | |
3.3% - 4% | |
Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness | |
2.5% - 3% | |
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant | |
2% - 2.4% | |
Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating | |
1.7% - 2.1% | |
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture | |
1.4% - 1.7% | |
1.2% - 1.4% | |
Helps oil and water mix together | |
0.9% - 1.15% | |
Helps oil and water mix together | |
0.7% - 1.1% | |
Used to preserve products, dissolve other ingredients and create a nice product texture | |
0.55% - 0.8% | |
Helps attract water to the upper layer of the skin | |
0.5% - 0.75% | |
Is helpful in restoring skin barrier function supporting its moisture levels. Is claimed to stimulte collagen production in skin but evidence is lacking | |
0.45% - 0.7% | |
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin | |
0.4% - 0.6% | |
Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants | |
0.4% - 0.65% | |
A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine | |
0.4% - 0.6% | |
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production | |
0.35% - 0.65% | |
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together | |
0.3% - 0.55% | |
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation | |
0.3% - 0.55% | |
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin | |
0.3% - 0.5% | |
A preservative. It helps prevent bacterial growth in cosmetic products | |
0.16% - 0.32% | |
A preservative | |
0.2% - 0.4% | |
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated | |
0.25% - 0.45% | |
0.2% - 0.4% | |
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties | |
0.3% - 0.55% | |
Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet | |
0.25% - 0.45% | |
0.25% - 0.45% | |
0.25% - 0.45% | |
Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking | |
0.25% - 0.5% | |
0.25% - 0.45% | |
Helps attract water to the upper layer of the skin and can help improve skin barrier function | |
0.25% - 0.45% | |
0.25% - 0.4% | |
Might help neutralize free radicals in skin | |
0.25% - 0.45% | |
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone | |
0.3% - 0.55% | |
Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air. | |
0.25% - 0.45% | |
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin | |
0.25% - 0.5% | |
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients. | |
0.25% - 0.5% | |
0.25% - 0.45% | |
0.25% - 0.5% | |
0.25% - 0.45% | |
Helps attract water to the upper layer of the skin and improves the product texture | |
0.25% - 0.45% | |
A mushroom extract that might have some skin-lightening and moisturizing properties, but solid research is lacking. It is unlikely to be effective in the concentration used in skincare products | |
0.25% - 0.5% | |
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation | |
0.25% - 0.5% | |
A preservative | |
0.25% - 0.45% | |
0.25% - 0.45% | |
0.25% - 0.4% | |
Helps to improve the product consistency | |
0.25% - 0.5% | |
Used to create a thicker product consistency | |
0.25% - 0.5% | |
Helps adjust the product pH and stabilize the formulation | |
0.25% - 0.45% | |
Helps stabilize the product formulation | |
0.3% - 0.55% | |
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin | |
0.25% - 0.45% | |
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating | |
0.35% - 0.6% | |
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles | |
0.3% - 0.55% | |
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles | |
0.3% - 0.55% | |
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles | |
0.25% - 0.45% | |
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles | |
0.3% - 0.5% | |
Helps oil and water mix together | |
0.25% - 0.5% | |
Helps water and oil mix together | |
0.3% - 0.55% | |
An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products | |
0.25% - 0.45% | |
Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating | |
0.25% - 0.45% | |
An algae extract that might have anti-oxidant properties | |
0.25% - 0.45% | |
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function | |
0.25% - 0.45% | |
Can work as an exfoliant but is typically used to adjust the product pH | |
0.25% - 0.45% | |
An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome) | |
0.25% - 0.45% | |
Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products | |
0.25% - 0.45% | |
A preservative | |
0.3% - 0.55% | |
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin | |
0.25% - 0.45% | |
A preservative | |
0.25% - 0.45% | |
0.25% - 0.5% | |
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin | |
0.3% - 0.5% | |
An emollient that is naturally found in skin | |
0.25% - 0.5% | |
A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect | |
0.2% - 0.4% | |
A preservative | |
0.2% - 0.35% | |
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations | |
0.25% - 0.4% | |
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness | |
0.15% - 0.3% | |
0.15% - 0.3% | |
0.15% - 0.25% | |
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin | |
0.1% - 0.15% | |
An aromatic blend of unspecified and possibly irritating ingredients | |
Show more |
Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritus
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Efficacy of a New Topical Nano-hyaluronic Acid in Humans
- Physiochemical properties and application of hyaluronic acid: a systematic review
- Profile of wound healing process induced by allantoin
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- A comparison of the relative antioxidant potency of L‐ergothioneine and idebenone
- l-Ergothioneine Protects Skin Cells against UV-Induced Damage—A Preliminary Study
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Skin permeation and antioxidant efficacy of topically applied resveratrol
- Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
- Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin
- Resveratrol as a Multifunctional Topical Hypopigmenting Agent
- Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation
- Resveratrol: A Unique Antioxidant Offering a Multi-Mechanistic Approach for Treating Aging Skin
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Compositions and methods for treating skin with extract from trametes
- Melia azedarach
- Preliminary and Pharmacological Profile of Melia azedarach L.: An Overview
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Epidermal and dermal effects of topical lactic acid
- Dual Effects of Alpha-Hydroxy Acids on the Skin
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils