CKD Guaranteed

CKD Guaranteed Retino Collagen Small Molecule 300 Guasha Neck Cream

Name: CKD Guaranteed - Retino Collagen Small Molecule 300 Guasha Neck Cream
Brand: CKD Guaranteed

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Niacinamide, Ceramide np + 39 more

Works well

What the product description says

“This cream is enriched with powerful ingredients that provide nourishment and deep hydration to the delicate skin on the neck, reducing wrinkles.”

Source: Soko Glam

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, hexapeptide-2, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.8–2.2%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.55%

Hexapeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.6–5.6%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.2–5.1%

Vinyl dimethiconeKey active· EmollientEffect: HighA type of silicone that helps to create a nice product texture and soften the upper layer of the skin~0.6–0.85%

Diisostearyl malateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin~0.5–0.75%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.45–0.65%

ErythritolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.35–0.65%

Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.3–0.55%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.3–0.55%

FructooligosaccharidesKey active· HumectantEffect: HighHelp attract water to the upper layer of the skin~0.25–0.5%

FructoseKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.25–0.5%

HistidineKey active· HumectantEffect: High~0.25–0.45%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.25–0.45%

LysineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

TyrosineKey activeEffect: High~0.25–0.45%

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.25–0.45%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.25–0.45%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.25–0.45%

Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.25–0.45%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.25–0.45%

GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.25–0.45%

ProlineKey activeEffect: Medium~0.25–0.5%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Chlorella vulgaris extractKey activeEffect: MediumA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.25–0.5%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.4%

CysteineKey activeEffect: HighMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.2–0.4%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3–3.6%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~2.3–2.8%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~1.2–1.5%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.5–0.75%

Caprylyl methiconeEffect: LowA type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin~0.35–0.65%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.3–0.5%

Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.3–0.55%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.15–0.25%

Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.4–0.6%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%

Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.25–0.45%

Anti-aging

Retinal, Niacinamide + 8 more

Works well

What the product description says

“Hydrolyzed Collagen Extract plumps and rejuvenates the neck, while Retinal reduces signs of aging.”

Source: Soko Glam

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal, adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: aspartic acid, hexapeptide-2, lysine, serine, threonine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.25–0.45%

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.8–2.2%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.25–0.45%

LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.25–0.45%

Hexapeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.4%

Evens skin tone

Side benefit · Retinal, Niacinamide + 3 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal.

In addition, this product contains niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine, cysteine.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.25–0.45%

CysteineEffect: LowMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.2–0.4%

Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.25–0.45%

Anti-blemish

Side benefit · Niacinamide, Retinal + 1 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, retinal. These ingredients is used for treating acne and can have a noticeable effect.

Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.25–0.45%

Anti-oxidation

Side benefit · Cysteine, Chlorella vulgaris extract + 5 more

May help

This product contains antioxidants (cysteine) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

CysteineKey activeEffect: MediumMight help neutralize free radicals in skin and might be helpful against hyperpigmentation~0.2–0.4%

Chlorella vulgaris extractEffect: LowA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties~0.25–0.5%

Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.25–0.45%

Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.25–0.45%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.25–0.45%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%

Can it cause trouble?

Irritancy

7 strong irritants: Citrus aurantium bergamia fruit oil, Ocimum sanctum leaf extract + 5 more — patch-test recommended

High risk

We flagged 18 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Citrus aurantium bergamia fruit oilA plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivityHigh~0.25–0.45%est.

Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.25–0.45%est.

Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.25–0.45%est.

Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.25–0.45%est.

RetinalOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritatingHigh~0.25–0.45%est.

Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.25–0.45%est.

Salvia sclarea oil—High~0.25–0.45%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.15%est.

LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.2–5.1%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~2.3–2.8%est.

1,2-hexanediolA preservativeMedium~0.65–1%est.

Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherMedium~0.65–1%est.

Diisostearyl malateHelps to soften the upper layer of the skinMedium~0.5–0.75%est.

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory propertiesMedium~0.25–0.5%est.

Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.25–0.45%est.

EthylhexylglycerinA preservativeMedium~0.25–0.5%est.

Caprylyl/capryl glucosideHelps oil and water mix together. Can be used as a cleansing agentMedium~0.25–0.5%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Chlorella vulgaris extractA plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties3/5~0.25–0.5%est.

Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.25–0.45%est.

Theobroma cacao seed extract—3/5~0.25–0.5%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.45–0.65%est.

Alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.6–5.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Caprylic/capric triglyceride~4.2–5.1%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Butylene glycol~3–3.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Pentylene glycol~2.3–2.8%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Niacinamide~1.8–2.2%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneAnti-blemishMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

1,2-hexanediol~0.65–1%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Cetearyl olivate~1.4–1.7%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Cetearyl olivate

Hydrogenated polyisobutene~1.2–1.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Sorbitan olivate~0.9–1.1%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan olivate

Polyglyceryl-3 methylglucose distearate~0.65–1%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-3 methylglucose distearate

Vinyl dimethicone~0.6–0.85%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of silicone that helps to create a nice product texture and soften the upper layer of the skin

More about Vinyl dimethicone

Diisostearyl malate~0.5–0.75%

Key activeIrritant · medium

Irritation risk: Medium

Works for

CleansingMoisturizing

Helps to soften the upper layer of the skin

More about Diisostearyl malate

Glyceryl stearate~0.5–0.75%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Caprylyl methicone~0.35–0.65%

Formula

Irritation risk: Low

Works for

Moisturizing

A type of silicone that helps to soften the upper layer of the skin and create a nice product finish on the skin

More about Caprylyl methicone

Erythritol~0.35–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin

More about Erythritol

Cetearyl alcohol~0.45–0.65%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Glucose~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Chlorella vulgaris extract~0.25–0.5%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

MoisturizingAnti-inflammatoryAnti-oxidation

A plant extract that can help to attract water to the upper layer of the skin and might have some anti-oxidant and anti-inflammatory properties

More about Chlorella vulgaris extract

Carbomer~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Ammonium acryloyldimethyltaurate/vp copolymer~0.25–0.45%

Formula

Irritation risk: Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer

Fructooligosaccharides~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Help attract water to the upper layer of the skin

More about Fructooligosaccharides

Fructose~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Fructose

Citrus aurantium bergamia fruit oil~0.25–0.45%

Irritant · high

Irritation risk: High

A plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivity

More about Citrus aurantium bergamia fruit oil

Melia azadirachta flower extract~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract

Ocimum sanctum leaf extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract

Palmitic acid~0.3–0.55%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid

Ethylhexylglycerin~0.25–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Dipotassium glycyrrhizate~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

Stearic acid~0.4–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

Adenosine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Melia azadirachta leaf extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract

Lavandula angustifolia oil~0.25–0.45%

Irritant · high

Irritation risk: High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil

Hydrogenated lecithin~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Sodium phytate~0.25–0.45%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Retinal~0.25–0.45%

Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-blemish

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

More about Retinal

Curcuma longa root extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract

Corallina officinalis extract~0.25–0.45%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract

Salvia sclarea oil~0.25–0.45%

Irritant · high

Irritation risk: High

More about Salvia sclarea oil

Hydrolyzed collagen~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen

Ceramide np~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Theobroma cacao seed extract~0.25–0.5%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Theobroma cacao seed extract

Dextrin~0.3–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Glycine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine

Serine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

Glutamic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Tromethamine~0.25–0.45%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Dipropylene glycol~0.25–0.45%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Cynanchum atratum extract~0.25–0.45%

Formula

Irritation risk: Low

More about Cynanchum atratum extract

Aspartic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Leucine~0.25–0.45%

Formula

Irritation risk: Low

More about Leucine

Alanine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Lysine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine

Arginine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Tyrosine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Phenylalanine~0.25–0.45%

Formula

Irritation risk: Low

More about Phenylalanine

Proline~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Valine~0.25–0.45%

Formula

Irritation risk: Low

More about Valine

Threonine~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Isoleucine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Histidine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Histidine

Methionine~0.25–0.4%

Formula

Irritation risk: Low

More about Methionine

Cysteine~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Might help neutralize free radicals in skin and might be helpful against hyperpigmentation

More about Cysteine

Hyaluronic acid~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Althaea rosea flower extract~0.2–0.35%

Formula

Irritation risk: Low

More about Althaea rosea flower extract

Tocopherol~0.2–0.35%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Caprylyl/capryl glucoside~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Caprylyl/capryl glucoside

Hexapeptide-2~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-2

Hydrolyzed elastin~0.2–0.35%

Formula

Irritation risk: Low

More about Hydrolyzed elastin

Biotin~0.15–0.25%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Limonene~0.05–0.15%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Linalool~0.05–0.1%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Ingredient list view

Water, Glycerin, Caprylic/capric triglyceride, Butylene glycol, Pentylene glycol, Niacinamide, 1,2-hexanediol, Cetearyl olivate, Hydrogenated polyisobutene, Sorbitan olivate, Polyglyceryl-3 methylglucose distearate, Vinyl dimethicone, Diisostearyl malate, Glyceryl stearate, Caprylyl methicone, Erythritol, Cetearyl alcohol, Glucose, Chlorella vulgaris extract, Carbomer, Ammonium acryloyldimethyltaurate/vp copolymer, Fructooligosaccharides, Fructose, Citrus aurantium bergamia fruit oil, Melia azadirachta flower extract, Ocimum sanctum leaf extract, Palmitic acid, Ethylhexylglycerin, Dipotassium glycyrrhizate, Stearic acid, Adenosine, Melia azadirachta leaf extract, Lavandula angustifolia oil, Hydrogenated lecithin, Sodium phytate, Retinal, Curcuma longa root extract, Corallina officinalis extract, Salvia sclarea oil, Hydrolyzed collagen, Ceramide np, Theobroma cacao seed extract, Dextrin, Glycine, Serine, Glutamic acid, Tromethamine, Dipropylene glycol, Cynanchum atratum extract, Aspartic acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Proline, Valine, Threonine, Isoleucine, Histidine, Methionine, Cysteine, Hyaluronic acid, Althaea rosea flower extract, Tocopherol, Caprylyl/capryl glucoside, Hexapeptide-2, Hydrolyzed elastin, Biotin, Limonene, Linalool

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	CKD GuaranteedRetino Collagen Small Molecule 300 Guasha Neck CreamYOUR PRODUCT	AHCYouth Lasting Real Eye Cream For Face	Dr.DifferentVITALIFT-A Eye & Neck	the Torriden StoreCellmazing Firming Cream
Match	—	79%	79%	76%
Price	—	$7.91	$30.00	$19.64
Shared key ingredients	—	21 of 29	4 of 29	20 of 29
Key difference	—	Acetyl Dipeptide-1 Cetyl Ester	Cholesterol	Panthenol
Irritancy	High	High	Medium	Medium
Drying alcohol	—	Contains drying alcohol	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredient list, "CKD Guaranteed - Retino Collagen Small Molecule 300 Guasha Neck Cream" can work well for skin moisturization. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. CKD Guaranteed - Retino Collagen Small Molecule 300 Guasha Neck Cream ticks this box. Humectants in this product (alanine, arginine, aspartic acid, erythritol and fructooligosaccharides) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide np, hydrolyzed collagen, vinyl dimethicone, arginine and caprylic/capric triglyceride) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

We particularly like that there is a good concentration of Niacinamide (1.80% - 2.20%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
This moisturizer contains an effective form of Retinoids (vitamin A): retinal 0.25% - 0.45%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of Retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternate days or when your skin feels dry.
As a plus, this moisturizer also contains Ceramides (ceramide np 0.30% - 0.55%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
This moisturizer also contains Peptides (hexapeptide-2 0.15% - 0.25%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Adenosine 0.25% - 0.45%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, stearic acid and dipotassium glycyrrhizate

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 29.25$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 33 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
3
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
4
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
5
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
6
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Functionncbi.nlm.nih.gov
7
Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmeticscir-safety.org
8
Oxidized citrus oil (R-limonene): A frequent skin sensitizer in Europesciencedirect.com
9
Air oxidation increases skin irritation from fragrance terpenesonlinelibrary.wiley.com
10
Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent modelresearchgate.net
11
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.ncbi.nlm.nih.gov
12
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
13
Melia azedarachmdedge.com
14
Preliminary and Pharmacological Profile of Melia azedarach L.: An Overviewjapsonline.com
15
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
16
Vaughn, A. R., Branum, A., & Sivamani, R. K. (2016). Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research, 30(8), 1243–1264. doi:10.1002/ptr.5640ncbi.nlm.nih.gov
17
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
18
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
19
Effect of Topical Application of Glycine and Proline on Recalcitrant Leg Ulcers of Prolidase Deficiencyjamanetwork.com
20
Functional glycine receptor in cultured human keratinocytesonlinelibrary.wiley.com
21
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
22
Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
23
Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proofncbi.nlm.nih.gov
24
In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmnessncbi.nlm.nih.gov
25
Combination of amino acids reduces pigmentation in B16F0 melanoma cellsncbi.nlm.nih.gov
26
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trialonlinelibrary.wiley.com
27
Histidine and/or Histidine Derivative for the Treatment of Inflammatory Skin Diseasespatents.google.com
28
Safety Assessment of α-Amino Acids as Used in Cosmeticsciteseerx.ist.psu.edu
29
The Potential Uses of N-acetylcysteine in Dermatology: A Reviewncbi.nlm.nih.gov
30
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
31
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
32
Vitamin E in dermatologyncbi.nlm.nih.gov
33
Vitamin E and Skin Healthlpi.oregonstate.edu

CKD GuaranteedRetino Collagen Small Molecule 300 Guasha Neck Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.