Dr. Different VITALIFT-A Eye & Neck
Works for
3 of 3 advertised claims delivered
Moisturizing24 ingredients credited for this claimStrong support
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, polyglutamic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide np, copper tripeptide-1, hexapeptide-9, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1, tripeptide-29
Evens skin tone2 ingredients credited for this claimStrong support
“Niacinamide also helps minimize the appearance of pores and targets discoloration and hyperpigmentation for double duty on brightening and evening skin tone.”
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Anti-aging13 ingredients credited for this claimStrong support
“Contains Retinol with rich Vitamin A and Peptide to improve wrinkles and loose skin.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal, adenosine.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, copper tripeptide-1, hexapeptide-9, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1, tripeptide-29.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Can it cause trouble?
Irritancy1 strong irritant: RetinalMedium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Cetyl ethylhexanoate~5.9–7.3%
- Irritation risk
- Medium
An emollient that helps soften the skin and creates a thicker product texture
More about Cetyl ethylhexanoateGlycerin~4.1–5%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinCarthamus tinctorius seed oil~3.1–3.8%
- Irritation risk
- Low
An emollient that helps soften the skin and might help calm down inflammation
More about Carthamus tinctorius seed oilSqualane~2.4–2.9%
- Irritation risk
- Low
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
More about SqualaneBrassica campestris sterols~1.9–2.4%
- Irritation risk
- Low
Help soften the upper layer of the skin
More about Brassica campestris sterolsButyrospermum parkii butter~1.7–2.1%
- Irritation risk
- Low
- Comedogenicity
- 3/5
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
More about Butyrospermum parkii butterCholesterol~1.4–1.8%
- Irritation risk
- Low
An emollient that is naturally found in skin
More about CholesterolPhytosteryl/behenyl/octyldodecyl lauroyl glutamate~1.1–1.4%
- Irritation risk
- Low
1,2-hexanediol~0.65–1%
Niacinamide~0.65–0.95%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamidePolyglyceryl-10 oleate~0.55–0.8%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Polyglyceryl-10 oleateHydrogenated lecithin~0.5–0.75%
- Irritation risk
- Low
Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.
More about Hydrogenated lecithinSodium hyaluronate~0.45–0.65%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronatePolyglutamic acid~0.4–0.6%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin.
More about Polyglutamic acidCeramide np~0.45–0.65%
- Irritation risk
- Low
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
More about Ceramide npTocopherol~0.35–0.65%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolStearic acid~0.5–0.7%
- Irritation risk
- Low
Helps oil and water mix together and works as an emollient
More about Stearic acidOleic acid~0.35–0.6%
- Irritation risk
- Medium
Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness
More about Oleic acidAdenosine~0.25–0.5%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineRetinal~0.25–0.5%
- Irritation risk
- High
One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating
More about RetinalDisodium edta~0.25–0.45%
Copper tripeptide-1~0.25–0.4%
- Irritation risk
- Low
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
More about Copper tripeptide-1Palmitoyl pentapeptide-4~0.2–0.4%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl pentapeptide-4Tripeptide-1~0.25–0.45%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Tripeptide-1Tripeptide-29~0.2–0.4%
Acetyl hexapeptide-8~0.2–0.35%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Hexapeptide-12~0.2–0.35%
- Irritation risk
- Low
Hexapeptide-9~0.15–0.3%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Hexapeptide-9Nicotinoyl tripeptide-35~0.15–0.3%
- Irritation risk
- Low
Nonapeptide-7~0.1–0.25%
- Irritation risk
- Low
Palmitoyl tetrapeptide-7~0.15–0.25%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tetrapeptide-7Palmitoyl tripeptide-1~0.1–0.2%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-1Palmitoyl tripeptide-29~0.05–0.1%
- Irritation risk
- Low
Ingredient list view
Water, Cetyl ethylhexanoate, Glycerin, Carthamus tinctorius seed oil, Squalane, Brassica campestris sterols, Butyrospermum parkii butter, Cholesterol, Phytosteryl/behenyl/octyldodecyl lauroyl glutamate, 1,2-hexanediol, Niacinamide, Polyglyceryl-10 oleate, Hydrogenated lecithin, Sodium hyaluronate, Polyglutamic acid, Ceramide np, Tocopherol, Stearic acid, Oleic acid, Adenosine, Retinal, Disodium edta, Copper tripeptide-1, Palmitoyl pentapeptide-4, Tripeptide-1, Tripeptide-29, Acetyl hexapeptide-8, Hexapeptide-12, Hexapeptide-9, Nicotinoyl tripeptide-35, Nonapeptide-7, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Palmitoyl tripeptide-29
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Dr. DifferentVITALIFT-A Eye & NeckYOUR PRODUCT | HSGNRetinally Liposomal Retinal Cream | NEOGEN X SUR.MEDICV.Biome Advanced Eye Cream | SWANICOCOPeptine Biome Eye Cream | |
|---|---|---|---|---|
| Match | — | 69% | 66% | 62% |
| Price | $20.24 | $13.20−$7.04 | $25.16+$4.92 | $18.00−$2.24 |
| Shared key ingredients | — | 13 of 20 | 14 of 20 | 11 of 20 |
| Key difference | — | Ascorbic Acid Polypeptide | Hexapeptide-11 | Acetyl Dipeptide-1 Cetyl Ester |
| Irritancy | Medium | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Product summary
Based on the ingredient list, "Dr. Different - VITALIFT-A Eye & Neck" can work well for skin moisturization. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Dr. Different - VITALIFT-A Eye & Neck ticks this box. Acetyl hexapeptide-8, hexapeptide-9, glycerin, polyglutamic acid and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1 and carthamus tinctorius seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- this moisturizer contains an effective form of Retinoids (vitamin A): retinal 0.25% - 0.50%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of Retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternate days or when your skin feels dry.
- As a plus, this moisturizer also contains Ceramides (ceramide np 0.45% - 0.65%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
- We like that this moisturizer contains peptides (palmitoyl tripeptide-1 0.10% - 0.20%, palmitoyl tetrapeptide-7 0.15% - 0.25%, palmitoyl pentapeptide-4 0.20% - 0.40%, hexapeptide-9 0.15% - 0.30%, copper tripeptide-1 0.25% - 0.40%, acetyl hexapeptide-8 0.20% - 0.35%, tripeptide-29 0.20% - 0.40% and tripeptide-1 0.25% - 0.45%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Adenosine 0.25% - 0.50%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Irritation risk
There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails from 30.00$ up to 40.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 20 studies and safety reviews.
- 1
- 2
- 3
- 4
- 5Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
- 6
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