HSGN Retinally Liposomal Retinal Cream

HSGN Retinally Liposomal Retinal Cream

Efficacy100/100IrritancyMedium

Works for

Anti-aging
Retinal, Niacinamide + 10 more
Works well
What the product description says
“Prevents and treats fine lines and wrinkles”
Source: beMUSED

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal, adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, ascorbic acid polypeptide, copper tripeptide-1, hexapeptide-9, palmitoyl pentapeptide-4, tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.05–0.2%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2.4%
Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.3%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.05–0.2%
Hexapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
Ascorbic acid polypeptideKey activeEffect: MediumA type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.05–0.2%
Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.05–0.2%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.05–0.2%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.05–0.3%
Evens skin tone
Retinal, Niacinamide
Works well
What the product description says
“Brightens and evens out skin tone and discoloration”
Source: beMUSED

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal.

In addition, this product contains niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.05–0.2%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2.4%
Anti-blemish
Not advertised by the brand · Niacinamide, Retinal + 3 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, retinal. These ingredients is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2.4%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.05–0.2%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.05–0.2%
Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.05–0.3%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.05–0.2%
Moisturizing
Not advertised by the brand · Niacinamide, Tripeptide-1 + 36 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, fructooligosaccharides.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, cholesterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ascorbic acid polypeptide, ceramide np, copper tripeptide-1, hexapeptide-9, niacinamide, palmitoyl pentapeptide-4, panthenol, tripeptide-1

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2.4%
Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.3%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.1–0.35%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.1–0.4%
Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Ascorbic acid polypeptideHeroEffect: HighA type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.05–0.2%
Hexapeptide-9Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.25%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.8–5.7%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~1.1–1.7%
Hydrogenated poly(c6-14 olefin)Key active· EmollientEffect: MediumHelps soften the upper layer of the skin and create a nice product texture~0.55–1.25%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.45–1%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.35–0.8%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.1–0.4%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.1–0.35%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.1–0.4%
Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.05–0.2%
FructooligosaccharidesKey active· HumectantEffect: HighHelp attract water to the upper layer of the skin~0.05–0.2%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.05–0.2%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.05–0.2%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.05–0.15%
Laminaria japonica extractKey activeEffect: HighSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties~0.05–0.2%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.05–0.25%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.05–0.25%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.05–0.2%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~0.05–0.3%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~0.05–0.25%
Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~3.5–5.2%
Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~1.3–2%
Pentaerythrityl tetraethylhexanoate· EmollientEffect: LowUsed to create a nice product consistency while softening the upper layer of the skin~1–1.45%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.1–0.3%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.1–0.35%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.05–0.15%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.05–0.2%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.15–0.5%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.05–0.2%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.05–0.3%
Anti-oxidation
Not advertised by the brand · Ficus carica fruit extract, Ascorbic acid polypeptide + 5 more
May help

This product contains antioxidants (ascorbic acid polypeptide, ficus carica fruit extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Ficus carica fruit extractKey activeEffect: MediumA plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect~0.05–0.2%
Ascorbic acid polypeptideKey activeEffect: MediumA type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.05–0.2%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.05–0.2%
Eclipta prostrata leaf extractEffect: LowA plant extract that is mostly used as a fragrance. Might have some anti-oxidant effect~0.05–0.15%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.1–0.3%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.05–0.3%

Can it cause trouble?

Irritancy
2 strong irritants: Eclipta prostrata leaf extract, Retinal
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Eclipta prostrata leaf extractA plant extract that is mostly used as a fragrance. Might have some anti-oxidant effectHigh~0.05–0.15%est.
RetinalOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritatingHigh~0.05–0.2%est.
1,2-hexanediolA preservativeMedium~1.1–1.7%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.15–0.5%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.05–0.3%est.
Ficus carica fruit extractA plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effectMedium~0.05–0.2%est.
Polyglyceryl-2 stearateHelps water and oil mix togetherMedium~0.05–0.25%est.
Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.1–0.35%est.
Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.05–0.25%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.2%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.05–0.25%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.05–0.2%est.
EthylhexylglycerinA preservativeMedium~0.01–0.1%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.05–0.15%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Laminaria japonica extractSeaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties3/5~0.05–0.2%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.35–0.8%est.
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~0.05–0.25%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.8–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cyclohexasiloxane~3.5–5.2%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Propanediol~2.5–3.8%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
1,2-hexanediol~1.1–1.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Niacinamide~1.6–2.4%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneAnti-blemishMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Dicaprylyl ether~1.3–2%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Betaine~1.1–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Pentaerythrityl tetraethylhexanoate~1–1.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product consistency while softening the upper layer of the skin

More about Pentaerythrityl tetraethylhexanoate
Hydrogenated poly(c6-14 olefin)~0.55–1.25%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Hydrogenated poly(c6-14 olefin)
Cetyl alcohol~0.45–1%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Cetearyl alcohol~0.35–0.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Cetearyl olivate~0.15–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Sorbitan olivate~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Caprylic/capric triglyceride~0.15–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Panthenol~0.1–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Hydrogenated lecithin~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Sodium hyaluronate~0.1–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Bisabolol~0.1–0.3%
Formula
Irritation risk
Low
Works for
Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Ceramide np~0.1–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Squalane~0.1–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Allantoin~0.05–0.2%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Hydrolyzed sodium hyaluronate~0.05–0.15%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Laminaria japonica extract~0.05–0.2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Seaweed extract that might help to attract water to the upper layer of the skin and have some anti-oxidant properties

More about Laminaria japonica extract
Eclipta prostrata leaf extract~0.05–0.15%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is mostly used as a fragrance. Might have some anti-oxidant effect

More about Eclipta prostrata leaf extract
Centella asiatica extract~0.05–0.3%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationAnti-inflammatoryReduces rednessMoisturizingAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Ficus carica fruit extract~0.05–0.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect

More about Ficus carica fruit extract
Polyglyceryl-2 stearate~0.05–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-2 stearate
Behenyl alcohol~0.1–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Glyceryl stearate~0.1–0.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Sodium stearoyl glutamate~0.1–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate
Stearyl alcohol~0.1–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Pentaerythrityl distearate~0.05–0.3%
Formula
Irritation risk
Low
Works for
Cleansing
More about Pentaerythrityl distearate
Sodium polyacryloyldimethyl taurate~0.05–0.25%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate
Glyceryl stearate se~0.05–0.25%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Cholesterol~0.1–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingCleansing

An emollient that is naturally found in skin

More about Cholesterol
C12-15 alkyl benzoate~0.05–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Beta-glucan~0.05–0.2%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationMoisturizingAnti-oxidationAnti-agingAnti-blemish

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan
Retinal~0.05–0.2%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingAnti-blemish

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

More about Retinal
Xanthan gum~0.05–0.25%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Adenosine~0.05–0.2%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Fructooligosaccharides~0.05–0.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Help attract water to the upper layer of the skin

More about Fructooligosaccharides
Disodium edta~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Butylene glycol~0.05–0.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Hydrolyzed hyaluronic acid~0.05–0.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Ascorbic acid polypeptide~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

A type of peptide. Might help neutralize free radicals in skin. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Ascorbic acid polypeptide
Sucrose distearate~0.1–0.3%
Formula
Irritation risk
Low
Works for
Cleansing
More about Sucrose distearate
Dipropylene glycol~0.05–0.2%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Tripeptide-1~0.1–0.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1
Hydroxypropyltrimonium hyaluronate~0.05–0.2%
Formula
Acetyl hexapeptide-8~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Copper tripeptide-1~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
Palmitoyl pentapeptide-4~0.05–0.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4
Hexapeptide-9~0.05–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-9
Sodium acetylated hyaluronate~0.05–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Sodium hyaluronate crosspolymer~0.05–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
Potassium hyaluronate~0.05–0.25%
Formula
Hyaluronic acid~0.05–0.2%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Phytosteryl/behenyl/octyldodecyl lauroyl glutamate~0.05–0.25%
Formula
Hydroxyacetophenone~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Ethylhexylglycerin~0.01–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Caprylyl glycol~0.05–0.15%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ingredient list view

Water, Glycerin, Cyclohexasiloxane, Propanediol, 1,2-hexanediol, Niacinamide, Dicaprylyl ether, Betaine, Pentaerythrityl tetraethylhexanoate, Hydrogenated poly(c6-14 olefin), Cetyl alcohol, Cetearyl alcohol, Cetearyl olivate, Sorbitan olivate, Caprylic/capric triglyceride, Panthenol, Hydrogenated lecithin, Sodium hyaluronate, Bisabolol, Ceramide np, Squalane, Allantoin, Hydrolyzed sodium hyaluronate, Laminaria japonica extract, Eclipta prostrata leaf extract, Centella asiatica extract, Ficus carica fruit extract, Polyglyceryl-2 stearate, Behenyl alcohol, Glyceryl stearate, Sodium stearoyl glutamate, Stearyl alcohol, Pentaerythrityl distearate, Sodium polyacryloyldimethyl taurate, Glyceryl stearate se, Cholesterol, C12-15 alkyl benzoate, Beta-glucan, Retinal, Xanthan gum, Adenosine, Fructooligosaccharides, Disodium edta, Butylene glycol, Hydrolyzed hyaluronic acid, Ascorbic acid polypeptide, Sucrose distearate, Dipropylene glycol, Tripeptide-1, Hydroxypropyltrimonium hyaluronate, Acetyl hexapeptide-8, Copper tripeptide-1, Palmitoyl pentapeptide-4, Hexapeptide-9, Sodium acetylated hyaluronate, Sodium hyaluronate crosspolymer, Potassium hyaluronate, Hyaluronic acid, Phytosteryl/behenyl/octyldodecyl lauroyl glutamate, Hydroxyacetophenone, Ethylhexylglycerin, Caprylyl glycol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
HSGNRetinally Liposomal Retinal CreamYOUR PRODUCTCKD GuaranteedRetino Collagen Small Molecule 300 Intensive CreamAbibYesStyle Exclusive PDRN Volume Fill-it Booster Crème 2.5 Tube Mini 5pcs Bundle SetArenciaRetinal Booster Shot
Match—84%80%79%
Price—$24.70$37.53$13.97
Shared key ingredients—20 of 2612 of 2613 of 26
Key difference—Nonapeptide-1Acetyl Tetrapeptide-5Hexapeptide-2
Irritancy Medium High Medium Medium
Drying alcohol————
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More alternatives: TOSOWOONG Collagen Lifting CreamMatkas Retinal 0.05% Capsule Hybrid Cream

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Product summary

Judging from the ingredient list, "HSGN - Retinally Liposomal Retinal Cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Acetyl hexapeptide-8, hexapeptide-9, betaine, fructooligosaccharides and glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide np, tripeptide-1, cholesterol, squalane and cetearyl alcohol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We particularly like that there is a good concentration of Niacinamide (1.60% - 2.40%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
  • This moisturizer contains an effective form of Retinoids (vitamin A): retinal 0.05% - 0.20%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of Retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternate days or when your skin feels dry.
  • As a plus, this moisturizer also contains Ceramides (ceramide np 0.10% - 0.40%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • We like that this moisturizer contains peptides (hexapeptide-9 0.05% - 0.25%, palmitoyl pentapeptide-4 0.05% - 0.20%, copper tripeptide-1 0.05% - 0.20%, acetyl hexapeptide-8 0.05% - 0.20%, tripeptide-1 0.10% - 0.30% and ascorbic acid polypeptide 0.05% - 0.20%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.05% - 0.20%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: centella asiatica extract, allantoin and caprylic/capric triglyceride

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 13.20$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 38 studies and safety reviews.

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HSGN Retinally Liposomal Retinal Cream
HSGNRetinally Liposomal Retinal Cream

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