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VT Cosmetics Reedle Shot Reti-A 100 Stick Pouch
VT Cosmetics

VT Cosmetics Reedle Shot Reti-A 100 Stick Pouch

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Retinol, Hydroxypinacolone retinoate + 7 more
Works well
What the product description says
“Reti-A”
Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains hydroxypinacolone retinoate, retinol, adenosine, bakuchiol, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside, madecassoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.25%
Hydroxypinacolone retinoateHeroEffect: HighA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.1–0.25%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.25%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.15–0.3%
MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.25%
AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.25%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.35%
Anti-blemish
Niacinamide, Retinol + 5 more
Works well
What the product description says
“unclog pores and smooth textured skin”
Source: Lila Beauty

This product can help reduce breakouts and clogged pores because it contains the following ingredient: hydroxypinacolone retinoate, niacinamide, retinol. These ingredients is used for treating acne and can have a noticeable effect.

In addition, this product contains bakuchiol. It can help in reducing blemishes, even though it is less effective.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.25%
Hydroxypinacolone retinoateHeroEffect: HighA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.1–0.25%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.15–0.3%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.5%
Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.35%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Moisturizing
Niacinamide, Madecassoside + 20 more
Works well
What the product description says
“small molecule Hyaluronic Acid to soothe and moisturize skin”
Source: Lila Beauty

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, ethylhexyl palmitate.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.25%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~1.9–2.4%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~1.1–1.4%
Polyglyceryl-6 stearateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.45–0.7%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.35%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.3%
Propolis extractKey activeEffect: MediumA complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritating~0.15–0.3%
Vitis vinifera fruit extractKey activeEffect: MediumA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.15–0.3%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.25%
Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.15%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.25%
Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.05–0.15%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.3–2.8%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.55–0.8%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.35%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.5%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.35%
Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.3%
Anti-oxidation
Side benefit · Bakuchiol, Madecassoside + 10 more
Works well

This product contains antioxidants (asiaticoside, bakuchiol, madecassoside, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.15–0.3%
MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.25%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.25%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.25%
Propolis extractEffect: LowA complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritating~0.15–0.3%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.25%
Zanthoxylum piperitum fruit extractEffect: LowPlant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smell~0.15–0.25%
Coffea arabica seed extractEffect: LowMight be helpful in neutralizing free radicals in skin~0.15–0.3%
Vitis vinifera fruit extractEffect: LowA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.15–0.3%
Polygonum cuspidatum root extractEffect: Low, below effective doseA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product~0.2–0.35%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.35%
Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%
Exfoliation
Side benefit · Retinol, Hydroxypinacolone retinoate + 1 more
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.25%
Hydroxypinacolone retinoateKey activeEffect: MediumA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.1–0.25%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.5%
Evens skin tone
Side benefit the brand mentions · Retinol, Hydroxypinacolone retinoate + 5 more
Works well
What the product description says
“Improves skin texture”
Source: Lila Beauty

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: hydroxypinacolone retinoate, retinol.

In addition, this product contains bakuchiol, niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.25%
Hydroxypinacolone retinoateHeroEffect: HighA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.1–0.25%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.8%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.15–0.3%
MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.25%
Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.3%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.25%

Can it cause trouble?

Irritancy
3 strong irritants: Hydroxypinacolone retinoate, Retinol + 1 more — patch-test recommended
High risk
We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hydroxypinacolone retinoateA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.High~0.1–0.25%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.15–0.25%est.
Propolis extractA complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritatingHigh~0.15–0.3%est.
Zanthoxylum piperitum fruit extractPlant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smellHigh~0.15–0.25%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~1.9–2.4%est.
1,2-hexanediolA preservativeMedium~0.65–0.95%est.
EthylhexylglycerinA preservativeMedium~0.25–0.45%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.
Caprylyl/capryl glucosideHelps oil and water mix together. Can be used as a cleansing agentMedium~0.2–0.4%est.
Sorbitan oleateHelps oil and water mix togetherMedium~0.15–0.3%est.
Polyglyceryl-6 behenateHelps oil and water mix togetherMedium~0.15–0.3%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.2–0.35%est.
BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.15–0.3%est.
Vitis vinifera fruit extractA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seedsMedium~0.15–0.3%est.
Polygonum cuspidatum root extractA plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the productMedium~0.2–0.35%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.1–0.25%est.
MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.15–0.25%est.
Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.1–0.15%est.
Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.05–0.15%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~1.1–1.4%est.
Sorbitan oleateHelps oil and water mix together2/5~0.15–0.3%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Dipropylene glycol~6.6–8.1%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Niacinamide~3.1–3.8%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-blemishEvens skin toneAnti-agingMoisturizingReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Butylene glycol~2.3–2.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Macadamia ternifolia seed oil~1.9–2.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Dimethyl isosorbide~1.6–2%
Formula
Irritation risk
Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide
1,2-hexanediol~0.65–0.95%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Ethylhexyl palmitate~1.1–1.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Sodium polyacrylate~0.95–1.15%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
Sodium acrylate/sodium acryloyldimethyl taurate copolymer~0.65–0.95%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Sodium acrylate/sodium acryloyldimethyl taurate copolymer
Glyceryl stearate~0.55–0.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Polyglyceryl-6 stearate~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Polyglyceryl-6 stearate
Polyisobutene~0.4–0.6%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Silica~0.5–0.8%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Hydroxypinacolone retinoate~0.1–0.25%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-agingEvens skin toneExfoliation

A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.

More about Hydroxypinacolone retinoate
Allantoin~0.25–0.5%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Glycereth-26~0.25–0.5%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Ethylhexylglycerin~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Xanthan gum~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Dipotassium glycyrrhizate~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Adenosine~0.15–0.25%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Caprylyl/capryl glucoside~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Caprylyl/capryl glucoside
Sorbitan oleate~0.15–0.3%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan oleate
Polyglyceryl-6 behenate~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together

More about Polyglyceryl-6 behenate
Sodium hyaluronate~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Lecithin~0.2–0.35%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Polysorbate 20~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Centella asiatica extract~0.2–0.35%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Retinol~0.15–0.25%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Bakuchiol~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-inflammatoryAnti-blemishEvens skin toneAnti-aging

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol
Helianthus annuus seed oil~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Beta-carotene~0.15–0.3%
Formula
Irritation risk
Low

A colorant adding orange or bright yellow color

More about Beta-carotene
Propolis extract~0.15–0.3%
Key activeIrritant · high
Irritation risk
High
Works for
MoisturizingAntibacterialAnti-oxidation

A complex substance produced by honey bees. Can have anti-bacterial and some anti-oxidant effect. Is an allergen and can be irritating

More about Propolis extract
Diospyros kaki leaf extract~0.15–0.25%
Formula
Irritation risk
Low
More about Diospyros kaki leaf extract
Vitis vinifera fruit extract~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds

More about Vitis vinifera fruit extract
Coffea arabica seed extract~0.15–0.3%
Formula
Irritation risk
Low
Works for
Anti-oxidation

Might be helpful in neutralizing free radicals in skin

More about Coffea arabica seed extract
Carthamus tinctorius flower extract~0.15–0.3%
Formula
Irritation risk
Low
More about Carthamus tinctorius flower extract
Polygonum cuspidatum root extract~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can contain resveratrol, an antioxidant that can help neutralize free radicals in skin. The effectiveness depends on the extract quality and concentration in the product

More about Polygonum cuspidatum root extract
Asiaticoside~0.1–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Castanea crenata shell extract~0.15–0.25%
Formula
Irritation risk
Low
More about Castanea crenata shell extract
Camellia sinensis leaf extract~0.15–0.25%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Zanthoxylum piperitum fruit extract~0.15–0.25%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smell

More about Zanthoxylum piperitum fruit extract
Madecassoside~0.15–0.25%
Hero · MoisturizingIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside
Madecassic acid~0.1–0.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid
Asiatic acid~0.05–0.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces irritationMoisturizing

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid
Ingredient list view

Water, Dipropylene glycol, Glycerin, Niacinamide, Butylene glycol, Macadamia ternifolia seed oil, Dimethyl isosorbide, 1,2-hexanediol, Ethylhexyl palmitate, Sodium polyacrylate, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Glyceryl stearate, Polyglyceryl-6 stearate, Polyisobutene, Silica, Hydroxypinacolone retinoate, Allantoin, Glycereth-26, Ethylhexylglycerin, Caprylyl glycol, Xanthan gum, Dipotassium glycyrrhizate, Adenosine, Caprylyl/capryl glucoside, Sorbitan oleate, Polyglyceryl-6 behenate, Sodium hyaluronate, Lecithin, Polysorbate 20, Centella asiatica extract, Retinol, Bakuchiol, Helianthus annuus seed oil, Beta-carotene, Propolis extract, Diospyros kaki leaf extract, Vitis vinifera fruit extract, Coffea arabica seed extract, Carthamus tinctorius flower extract, Polygonum cuspidatum root extract, Asiaticoside, Castanea crenata shell extract, Camellia sinensis leaf extract, Zanthoxylum piperitum fruit extract, Madecassoside, Madecassic acid, Asiatic acid

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
VT CosmeticsReedle Shot Reti-A 100 Stick PouchYOUR PRODUCTISNTREEHyper Retinol EX 1.0 SerumMedicubeDeep Reviving Bakuchiol Retinol SerumSome By MiRetinol Intense Reactivating Serum Large Size
Match—80%78%71%
Price—$13.71$19.78$34.48
Shared key ingredients—9 of 1710 of 1712 of 17
Key difference—Copper Tripeptide-1Retinyl RetinoateRetinal
Irritancy High Medium High High
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 47 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  3. 3
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  4. 4
    Fatty acids profile of oil from nine varieties of Macadamia nuttandfonline.com
  5. 5
    Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositionspatents.google.com
  6. 6
    The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
VT Cosmetics Reedle Shot Reti-A 100 Stick Pouch
VT CosmeticsReedle Shot Reti-A 100 Stick Pouch
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