What's In My Jar
Glowbiotics MD Retinol Anti-Aging and Brightening Treatment
Glowbiotics MD

Glowbiotics MD Retinol Anti-Aging and Brightening Treatment

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Retinol, Hydroxypinacolone retinoate + 6 more
Works well
What the product description says
“Retinol Anti-Aging and Brightening Treatment”
From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains hydroxypinacolone retinoate, retinol, bakuchiol, gluconic acid, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: myristoyl nonapeptide-3.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.5%
Hydroxypinacolone retinoateHeroEffect: HighA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.01–0.05%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.3–0.55%
Myristoyl nonapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Gluconic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.3%
Lactococcus ferment lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~2.3–2.8%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.45%
Moisturizing
Niacinamide, Myristoyl nonapeptide-3 + 14 more
Works well
What the product description says
“Lightweight and quick-absorbing, it repairs and renews aging skin while you sleep.”
Source: Skinstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, polyglycerin-3.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed wax, jojoba esters.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: myristoyl nonapeptide-3, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
Myristoyl nonapeptide-3HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.7–5.7%
Lactococcus ferment lysateKey activeEffect: HighConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~2.3–2.8%
Carthamus tinctorius oleosomesKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~1.9–2.4%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.55–0.85%
Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.45–0.7%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.4–0.6%
Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.45%
Helianthus annuus seed waxKey active· EmollientEffect: HighHelps soften the upper layer of the skin and support skin's barrier function while creating a thicker product consistency~0.25–0.5%
Polyglycerin-3Key active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.2–0.4%
Gluconic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.3%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~3.1–3.8%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~1.2–1.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.45–0.7%
Evens skin tone
Retinol, Hydroxypinacolone retinoate + 5 more
Works well
What the product description says
“An innovative Pigment Balancing Complex of botanicals and photo-protective actives brightens and clarifies skin; it helps to reduce dark spots, pigmentation and uneven tone to reveal a radiant, healthy complexion come morning.”
Source: Skinstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: hydroxypinacolone retinoate, retinol.

In addition, this product contains bakuchiol, gluconic acid, niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: hexylresorcinol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.5%
Hydroxypinacolone retinoateHeroEffect: HighA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.01–0.05%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.3–0.55%
Gluconic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.3%
HexylresorcinolEffect: LowMight be helpful in reducing hyperpigmentation and neutralizing free radicals in skin~0.5–0.75%
Pisum sativum extractEffect: Low, below effective doseMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking~0.25–0.45%
Anti-blemish
Side benefit · Niacinamide, Retinol + 4 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: hydroxypinacolone retinoate, retinol. These ingredients is used for treating acne and can have a noticeable effect.

In addition, this product contains bakuchiol, gluconic acid, niacinamide. It can help in reducing blemishes, even though it is less effective.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.5%
Hydroxypinacolone retinoateHeroEffect: HighA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.01–0.05%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.3–0.55%
Gluconic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.3%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.45%
Anti-oxidation
Side benefit · Hexylresorcinol, Bakuchiol + 5 more
Works well

This product contains antioxidants (bakuchiol, gluconic acid, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - hexylresorcinol also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

HexylresorcinolKey activeEffect: MediumMight be helpful in reducing hyperpigmentation and neutralizing free radicals in skin~0.5–0.75%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.3–0.55%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.5%
Gluconic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.3%
Lactococcus ferment lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin~2.3–2.8%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.45%
Terminalia ferdinandiana fruit extractEffect: LowA plant extract that might have some anti-oxidant effect in skin, but evidence is lacking~0.25–0.5%
Exfoliation
Side benefit · Retinol, Gluconic acid + 1 more
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconic acid, retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.25–0.5%
Gluconic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.15–0.3%
Hydroxypinacolone retinoateKey activeEffect: MediumA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.~0.01–0.05%

Can it cause trouble?

Irritancy
3 strong irritants: Retinol, Hydroxypinacolone retinoate + 1 more — patch-test recommended
High risk
We flagged 22 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.25–0.5%est.
Hydroxypinacolone retinoateA derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.High~0.01–0.05%est.
Acacia decurrens flower waxUsed as a fragrance. Can be irritatingHigh~0.25–0.45%est.
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~0.2–0.4%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~3.1–3.8%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~1.4–1.7%est.
HexylresorcinolMight be helpful in reducing hyperpigmentation and neutralizing free radicals in skinMedium~0.5–0.75%est.
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.45–0.7%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.45–0.7%est.
BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.3–0.55%est.
Terminalia ferdinandiana fruit extractA plant extract that might have some anti-oxidant effect in skin, but evidence is lackingMedium~0.25–0.5%est.
Pisum sativum extractMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lackingMedium~0.25–0.45%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
Sucrose dilaurateHelps oil and water mix together. Can be used as a cleansing agentMedium~0.3–0.5%est.
Caprylhydroxamic acidA preservativeMedium~0.2–0.4%est.
Sodium cocoyl glutamateHelps oil and water mix togetherMedium~0.3–0.6%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.4%est.
Gluconic acidA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.15–0.3%est.
1,2-hexanediolA preservativeMedium~0.1–0.2%est.
BhtA preservativeMedium~0.15–0.25%est.
Benzoic acidA preservativeMedium~0.15–0.25%est.
BhaHelps preserve the product formulationMedium~0.05–0.1%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.4–0.6%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.55–0.85%est.
Alternatives
The closest match we found
Deep Reviving Bakuchiol Retinol Serum
Medicube Deep Reviving Bakuchiol Retinol Serum
Closest match79% match
$19.61
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.7–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Niacinamide~4.2–5.1%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
MoisturizingAnti-blemishAnti-agingEvens skin toneReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Pentylene glycol~3.1–3.8%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Lactococcus ferment lysate~2.3–2.8%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-oxidationAnti-aging

Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin

More about Lactococcus ferment lysate
Carthamus tinctorius oleosomes~1.9–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Carthamus tinctorius oleosomes
Cetearyl olivate~1.6–2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Potassium cetyl phosphate~1.4–1.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Behenyl alcohol~1.2–1.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Sorbitan olivate~0.95–1.15%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Glyceryl cocoate~0.7–1.05%
Formula
Irritation risk
Low
Works for
Cleansing
More about Glyceryl cocoate
Lauryl lactate~0.6–0.9%
Formula
Irritation risk
Low
More about Lauryl lactate
Hexylresorcinol~0.5–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin

More about Hexylresorcinol
Cetearyl alcohol~0.55–0.85%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Maltodextrin~0.45–0.65%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Jojoba esters~0.45–0.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Caprylic/capric triglyceride~0.45–0.7%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Ethylhexyl palmitate~0.4–0.6%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Retinol~0.25–0.5%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Hydroxypinacolone retinoate~0.01–0.05%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishEvens skin toneAnti-agingExfoliation

A derivative of the most potent form of vitamin A, retinoic acid. The ingredient can be sold under name Granactive Retinoid. Note that if a skincare brand discloses the concentration of Granactive Retinoid in a product, the concentration refers to a diluted form of Hydroxypinacolone Retinoate: 1% of Granactive Retinoid corresponds to 0.1% of Hydroxypinacolone Retinoate. Hydroxypinacolone Retinoate (HPR) is a unique derivative of retinoic acid because it can directly work in the skin and does not require additional conversion steps. According to studies done by the manufacturer on models of human skin (not real people), this derivative is more effective than other cosmetic versions of retinoids (such as retinol, retinaldehyde, and retinyl palmitate), and, at the same time, causes less irritation. It has been also demonstrated to be more stable than retinol which makes formulating with easier and increases the chances that a product with it will maintain its effectiveness after opening. The packaging should still ideally be air-tight. HPR is available over the counter in the EU, UK, Asia, Australia and New Zealand, but is only with a prescription in Canada.

More about Hydroxypinacolone retinoate
Bakuchiol~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-agingAnti-oxidationEvens skin toneAnti-blemish

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol
Terminalia ferdinandiana fruit extract~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect in skin, but evidence is lacking

More about Terminalia ferdinandiana fruit extract
Terminalia chebula fruit extract~0.25–0.45%
Formula
Irritation risk
Low
More about Terminalia chebula fruit extract
Beta-glucan~0.25–0.45%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationMoisturizingAnti-blemishAnti-oxidationAnti-aging

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan
Myristoyl nonapeptide-3~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Myristoyl nonapeptide-3
Pisum sativum extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking

More about Pisum sativum extract
Acacia decurrens flower wax~0.25–0.45%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Acacia decurrens flower wax
Helianthus annuus seed wax~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and support skin's barrier function while creating a thicker product consistency

More about Helianthus annuus seed wax
Dimethyl isosorbide~0.25–0.45%
Formula
Irritation risk
Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sucrose dilaurate~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Sucrose dilaurate
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Hydroxyethylcellulose~0.25–0.45%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Caprylhydroxamic acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
Sodium cocoyl glutamate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium cocoyl glutamate
Alcohol denat.~0.2–0.4%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Disodium edta~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Polyglycerin-3~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Polyglycerin-3
Gluconic acid~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-blemishExfoliationEvens skin toneAnti-oxidationMoisturizingAnti-aging

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in imporved hydration levels. It has been shown to be helpful against acne and clogged pores. Might help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconic acid
Sodium benzoate~0.15–0.3%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Sodium acetate~0.15–0.3%
Formula
Irritation risk
Low
More about Sodium acetate
1,2-hexanediol~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Bht~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Cellulose~0.15–0.3%
Formula
Irritation risk
Low
Works for
Mattifying

Can be used to help absorb oil as well as add volume and imporve texture of products.

More about Cellulose
Benzoic acid~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Benzoic acid
Bha~0.05–0.1%
Irritant · medium
Irritation risk
Medium

Helps preserve the product formulation

More about Bha
Ingredient list view

Water, Glycerin, Niacinamide, Pentylene glycol, Lactococcus ferment lysate, Carthamus tinctorius oleosomes, Cetearyl olivate, Potassium cetyl phosphate, Behenyl alcohol, Sorbitan olivate, Glyceryl cocoate, Lauryl lactate, Hexylresorcinol, Cetearyl alcohol, Maltodextrin, Jojoba esters, Caprylic/capric triglyceride, Ethylhexyl palmitate, Retinol, Hydroxypinacolone retinoate, Bakuchiol, Terminalia ferdinandiana fruit extract, Terminalia chebula fruit extract, Beta-glucan, Myristoyl nonapeptide-3, Pisum sativum extract, Acacia decurrens flower wax, Helianthus annuus seed wax, Dimethyl isosorbide, Caprylyl glycol, Sucrose dilaurate, Xanthan gum, Hydroxyethylcellulose, Polysorbate 20, Caprylhydroxamic acid, Sodium cocoyl glutamate, Alcohol denat., Disodium edta, Polyglycerin-3, Gluconic acid, Sodium benzoate, Sodium acetate, 1,2-hexanediol, Bht, Cellulose, Benzoic acid, Bha

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Glowbiotics MDRetinol Anti-Aging and Brightening TreatmentYOUR PRODUCTMedicubeDeep Reviving Bakuchiol Retinol SerumDr Naomi SkinVitamin AmenISNTREEHyper Retinol EX 1.0 Serum
Match—79%78%73%
Price—$19.61$94.32$13.54
Shared key ingredients—7 of 145 of 145 of 14
Key difference—Retinyl RetinoateAcetyl GlucosamineCopper Tripeptide-1
Irritancy High High High Medium
Drying alcohol Contains drying alcohol ———
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  3. 3
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  4. 4
    Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
  5. 5
    Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
  6. 6
    A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
Glowbiotics MD Retinol Anti-Aging and Brightening Treatment
Glowbiotics MDRetinol Anti-Aging and Brightening Treatment
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