Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
- Exfoliation
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"The Organic Pharmacy - Gene Expression Lifting Serum" is effective for: Anti-inflammatory, Anti-aging, Exfoliation, Moisturizing, Evens skin tone and Anti-blemish
Ingredient callouts
- This product contains acids (gluconolactone 0.55% - 1.35%). Their concentration is low, and they will not have a strong exfoliating effect. Instead, they work to support the skin natural acid mantle and to attract water (as humectants). PHAs (gluconolactone) especially are great for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
- This product contains an effective form of Retinoids (vitamin A): retinol 0.20% - 0.75%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
- Peptides (trifluoroacetyl tripeptide-2 0.10% - 0.50%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Humectants (sodium hyaluronate 3.10% - 4.70%, isomalt 0.45% - 1.00%, dextran 1.10% - 1.70% and glycerin 4.30% - 6.50%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails from 58.50£ up to 195.00£ in the United Kingdom and for 195.00$ in the United States.
For a detailed price comparison: click here.
Anti-aging
What does the product description say?
An anti-ageing superhero, The Organic Pharmacy Gene Expression Lifting Serum helps to rejuvenate your face to create a more youthful illusion that’s brimming with vitality.
Source: Lookfantastic
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: trifluoroacetyl tripeptide-2, vitis vinifera seed extract.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Anti-oxidation
This product contains antioxidants (retinol, vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Evens skin tone
What does the product description say?
It also helps to improve the appearance of hyperpigmentation, evening out your skin tone for a clearer look and feel.
Source: Lookfantastic
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glucosamine hcl.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Moisturizing
What does the product description say?
To ensure hydration is consistently maintained, Glucosamine locks in moisture, leaving skin feeling soft and replenished.
Source: Lookfantastic
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
biosaccharide gum-1, dextran.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract, lecithin.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: trifluoroacetyl tripeptide-2
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps attract water to the most upper layer of the skin. Derived from sugar
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps attract water to the upper layer of the skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency
Helps attract water to the upper layer of the skin
Helps attract water to the most upper layer of the skin. Derived from sugar
Potential irritants
A preservative. Can be used to mask unpleasant smell. Can be irritating
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Comedogenic ingredients
Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency
All ingredients
Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin
Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light
A preservative. Can be used to mask unpleasant smell. Can be irritating
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
An umbrella term for the following three colorants: CI 77491, CI 77492, CI 77499. They might be able to offer some protection against visible light, but the degree of the protection is not clear
Helps attract water to the upper layer of the skin and is claimed to provide a longer-lasting hydration because of its ability to create a water-binding film on the surface of the skin
A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Helps attract water to the most upper layer of the skin. Derived from sugar
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A common frangrance that can easily irritate skin, especially if exposed to air, light or heat
Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating
Ingredient list view
Aloe barbadensis extract, Water, Glycerin, Titanium dioxide, Mica, Benzyl alcohol, Sodium hyaluronate, Silica, Carbomer, Hibiscus sabdariffa leaf extract, Linum usitatissimum seed extract, Sodium hydroxide, Xanthan gum, Glucosamine hcl, Lecithin, Iron oxides, Biosaccharide gum-1, Sorbic acid, Vitis vinifera seed extract, Phospholipids, Chondrus crispus extract, Isomalt, Gluconolactone, Retinol, Dextran, Trifluoroacetyl tripeptide-2, Geraniol, Citronellol, Linalool, Eugenol, Limonene, Citral, Farnesol, Benzyl benzoate, Benzyl salicylate, Isoeugenol
- Glycerol and the skin: holistic approach to its origin and functions
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Glucosamine: an ingredient with skin and other benefits
- Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmetics
- The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healing
- Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids
- Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Light
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts