Works for
MoisturizingNiacinamide, Acetyl hexapeptide-8 + 9 moreWorks well
“Intensely moisturizes skin up to 24 hours after application”
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin, methyl gluceth-20.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate, niacinamide
Anti-agingNiacinamide, Gluconolactone + 4 moreWorks well
“P-TIOX is a peptide-powered serum inspired by the effects of anti-wrinkle neurotoxin injections, proven to reduce the appearance of 9 types of expression lines and reveal glass skin radiance.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, gluconolactone, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, dipeptide diaminobutyroyl benzylamide diacetate.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Anti-blemishSide benefit · Niacinamide, Salicylic acid + 1 moreWorks well
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, salicylic acid. These ingredients is used for treating acne and can have a noticeable effect.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: gluconolactone
ExfoliationSide benefit · Gluconolactone, Salicylic acidWorks well
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone, salicylic acid.
Evens skin toneSide benefit · Niacinamide, Gluconolactone + 1 moreWorks well
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone, niacinamide, salicylic acid
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Anti-oxidationSide benefit · Gluconolactone, Adenosine + 1 moreMay help
This product contains antioxidants (gluconolactone) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.
Can it cause trouble?
Irritancy1 strong irritant: Alcohol denat.Medium risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
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Ingredients
Filter by role to see what each ingredient is doing.
Water~40–60%
Niacinamide~5.6–8.3%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideGluconolactone~3.7–5.5%
- Irritation risk
- Medium
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
More about GluconolactoneButylene glycol~2.7–4%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolPeg/ppg/polybutylene glycol-8/5/3 glycerin~2–3%
- Irritation risk
- Low
Helps create a nice product texture and attract water to the upper layer of the skin
More about Peg/ppg/polybutylene glycol-8/5/3 glycerinAlcohol denat.~1.6–2.4%
- Irritation risk
- High
Produces temporary toning effect. Can help dissolve other ingredients or preserve products
More about Alcohol denat.Pentylene glycol~1.4–2.1%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolMethyl gluceth-20~1.1–1.7%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and soften it
More about Methyl gluceth-20Glycerin~1–1.5%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPotassium hydroxide~0.6–1.35%
Hydroxyethylcellulose~0.45–1.1%
- Irritation risk
- Low
Used to thicken product formulations and create gel-like textures
More about HydroxyethylcelluloseSalicylic acid~0.35–0.75%
- Irritation risk
- High
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
More about Salicylic acidChlorphenesin~0.16–0.32%
Phytic acid~0.15–0.65%
- Irritation risk
- Medium
An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics
More about Phytic acidAdenosine~0.1–0.5%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineSodium benzoate~0.1–0.35%
Laminaria digitata extract~0.05–0.2%
- Irritation risk
- Low
- Comedogenicity
- 3/5
Seaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment
More about Laminaria digitata extractDipeptide diaminobutyroyl benzylamide diacetate~0.05–0.15%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Dipeptide diaminobutyroyl benzylamide diacetateAcetyl hexapeptide-8~0.05–0.1%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Ingredient list view
Water, Niacinamide, Gluconolactone, Butylene glycol, Peg/ppg/polybutylene glycol-8/5/3 glycerin, Alcohol denat., Pentylene glycol, Methyl gluceth-20, Glycerin, Potassium hydroxide, Hydroxyethylcellulose, Salicylic acid, Chlorphenesin, Phytic acid, Adenosine, Sodium benzoate, Laminaria digitata extract, Dipeptide diaminobutyroyl benzylamide diacetate, Acetyl hexapeptide-8
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| SkinCeuticalsP-TIOXYOUR PRODUCT | innisfreeGentle Retinol Salicylic Acne Serum | Skin Inc Supplement BarSerum Booster Shot - Clarify | Versed SkinJust Breathe Clarifying Serum | |
|---|---|---|---|---|
| Match | — | 78% | 77% | 77% |
| Price | $150.00 | $34.00−$116.00 | $35.70−$114.30 | $13.98−$136.02 |
| Shared key ingredients | — | 4 of 7 | 4 of 7 | 3 of 7 |
| Key difference | — | Retinol | Hydrolyzed Hyaluronic Acid | Panthenol |
| Irritancy | Medium | Medium | Medium | Low |
| Drying alcohol | Contains drying alcohol | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Radiant Glow Botanical Advanced Acne SerumHorace Sérum Acide Salicylique 2 % + Niacinamide 3 %
Product summary
"SkinCeuticals - P-TIOX" is effective for: Anti-aging, Exfoliation, Moisturizing, Evens skin tone and Anti-blemish
Ingredient callouts
- A good concentration of Niacinamide (5.60% - 8.30%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Exfoliating acids (). In this concentration, they will have a noticeable exfoliating effect. They can also have an anti-aging effect and stimulate collagen production in a long-run. PHAs (gluconolactone 3.70% - 5.50%) in this product also work for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
- Peptides (acetyl hexapeptide-8 0.05% - 0.10% and dipeptide diaminobutyroyl benzylamide diacetate 0.05% - 0.15%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Salicylic acid (0.40% - 0.90%). This is an oil-soluble exfoliating acid. Because of this property, it can work inside pores and help reduce the congestion. It has an anti-inflammatory effect and is used to treat acne. Because it is a quite strong exfoliator, be careful with using this product too often: it could result in over-exfoliation.
- Adenosine 0.15% - 0.50%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
- Humectants (acetyl hexapeptide-8 0.05% - 0.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 150.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 21 studies and safety reviews.
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