Skinbetter Science

Skinbetter Science Alto Advanced Antioxidant Defense

Name: Skinbetter Science - Alto Advanced Antioxidant Defense
Brand: Skinbetter Science

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Anti-aging

Niacinamide, Arabidopsis thaliana extract + 9 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: arabidopsis thaliana extract, carnosine, palmitoyl tripeptide-1, vitis vinifera seed extract.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%

Arabidopsis thaliana extractKey activeEffect: MediumPlant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking~0.25–0.45%

Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.2–0.4%

CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.2–0.4%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.15–0.3%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.2–0.4%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%

Tetrahexyldecyl ascorbateUnder-dosedBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.35–0.6%

Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.15–0.3%

Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.15–0.3%

Evens skin tone

Niacinamide, Glycyrrhiza glabra root extract + 4 more

Works well

What the product description says

“Alto Advanced Defense and Repair Serum Improving skin brightness, repairing redness, overall tone and texture as a result of free radical damage from environmental and intrinsic stressors.”

Source: SkinBetter

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.25–0.45%

Anti-blemish

Side benefit · Niacinamide, Linoleic acid + 2 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: linoleic acid

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%

Linoleic acidKey activeEffect: MediumAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.25–0.5%

PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.2–0.35%

Moisturizing

Side benefit · Niacinamide, Linoleic acid + 33 more

Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, carnosine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, cholesterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ap, ceramide eop, ceramide np, linoleic acid, niacinamide, palmitoyl tripeptide-1, phytosphingosine

Linoleic acidHero· EmollientEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.25–0.5%

Ceramide apHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.35%

Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.35%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.35%

PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.2–0.35%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Ethylhexyl olivateKey activeEffect: HighHelps soften the upper layer of the skin~3–3.6%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.2–2.7%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.5–0.75%

Linolenic acidKey active· EmollientEffect: HighAn emollient that helps soften the skin and calm down inflammation~0.25–0.4%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.25–0.4%

Diisostearyl malateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin~0.25–0.45%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.2–0.4%

Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~0.2–0.4%

CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.2–0.4%

Helianthus annuus seed ceraKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.2–0.4%

Polyglycerin-3Key active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.2–0.4%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.2–0.4%

Acacia decurrens flower ceraKey active· EmollientEffect: MediumMimosa flower fax. Helps soften the upper layer of the skin. It adds a nice smell, but could be irritating~0.2–0.4%

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.15–0.3%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.15–0.25%

Micrococcus lysateKey activeEffect: HighConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"~0.15–0.25%

Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.15–0.3%

Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.15–0.25%

Plankton extractKey activeEffect: MediumCan help attract water to the upper layer of the skin~0.15–0.25%

Methyl gluceth-20Key active· HumectantEffect: MediumHelps attract water to the upper layer of the skin and soften it~0.15–0.3%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~5.4–6.5%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.2–0.4%

Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.2–0.35%

Olea europaea fruit extract· EmollientEffect: LowAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.15–0.3%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%

Anti-oxidation

Side benefit · Carnosine, Vitis vinifera seed extract + 16 more

Works well

This product contains antioxidants (carnosine, superoxide dismutase, ubiquinone, vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.2–0.4%

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.2–0.4%

Buddleja officinalis flower extractEffect: LowA plant flower extract that might help calm down inflammation in skin and neutralize free radicals, but evidence of effectiveness in skin is lacking~0.25–0.5%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.25–0.45%

Taraxacum officinale rhizome/root extractEffect: LowA plant extract that might have some anti-oxidant properties~0.2–0.4%

Micrococcus lysateEffect: LowConsists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"~0.15–0.25%

Coffea arabica seed extractEffect: LowMight be helpful in neutralizing free radicals in skin~0.1–0.2%

Euterpe oleracea fruit extractEffect: LowA plant extract that can have some anti-oxidant effect in skin~0.1–0.2%

Zingiber officinale root extractEffect: LowA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking~0.05–0.15%

BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.15–0.25%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.3%

ErgothioneineUnder-dosedCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.25–0.5%

Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.2–0.4%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%

Can it cause trouble?

Irritancy

2 strong irritants: Zingiber officinale root extract, Alcohol

Medium risk

We flagged 24 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Taraxacum officinale rhizome/root extractA plant extract that might have some anti-oxidant propertiesHigh~0.2–0.4%est.

Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.15–0.25%est.

Buddleja officinalis flower extractA plant flower extract that might help calm down inflammation in skin and neutralize free radicals, but evidence of effectiveness in skin is lackingHigh~0.25–0.5%est.

Zingiber officinale root extractA plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lackingHigh~0.05–0.15%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.15–0.3%est.

Acacia decurrens flower ceraMimosa flower fax. Helps soften the upper layer of the skin. It adds a nice smell, but could be irritatingHigh~0.2–0.4%est.

AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.2–0.35%est.

Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.25–0.45%est.

Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.35–0.6%est.

Arabidopsis thaliana extractPlant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lackingMedium~0.25–0.45%est.

Euterpe oleracea fruit extractA plant extract that can have some anti-oxidant effect in skinMedium~0.1–0.2%est.

Plankton extractCan help attract water to the upper layer of the skinMedium~0.15–0.25%est.

Linolenic acidAn emollient that helps soften the skin and calm down inflammationMedium~0.25–0.4%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.3%est.

Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~0.2–0.4%est.

Sodium lauroyl lactylateHelps water and oil mix togetherMedium~0.2–0.4%est.

Diisostearyl malateHelps to soften the upper layer of the skinMedium~0.25–0.45%est.

Steareth-2Helps oil and water mix togetherMedium~0.2–0.4%est.

Acacia senegal gumHelps mask the small of other ingredients and improve the product textureMedium~0.25–0.4%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.2–0.4%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.

EthylhexylglycerinA preservativeMedium~0.2–0.4%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.15–0.3%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.2–0.4%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Theobroma cacao seed extract—3/5~0.15–0.3%est.

Plankton extractCan help attract water to the upper layer of the skin3/5~0.15–0.25%est.

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.25–0.4%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.2–2.7%est.

Alternatives

The closest match we found

Daughters of Malay Post-Breakout Recovery Serum

Closest match81% match

View all alternatives

User reviews

Would you recommend?

No community reviews yet.

Be the first — your take helps the next person decide.

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Butylene glycol~5.4–6.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Propanediol~3.8–4.6%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Ethylhexyl olivate~3–3.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Ethylhexyl olivate

Cetearyl alcohol~2.2–2.7%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Chlorogenic acids~1.7–2%

Formula

Irritation risk: Low

More about Chlorogenic acids

Niacinamide~1.4–1.8%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Lauryl lactate~1.2–1.5%

Formula

Irritation risk: Low

More about Lauryl lactate

Dimethyl isosorbide~0.95–1.15%

Formula

Irritation risk: Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide

Pyrroloquinoline quinone allyl ester~0.65–1%

Formula

Irritation risk: Low

More about Pyrroloquinoline quinone allyl ester

Hydrolyzed sodium hyaluronate~0.5–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Glycyrrhiza glabra root extract~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Reduces rednessEvens skin toneAnti-oxidationAnti-inflammatoryAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract

Tetrahexyldecyl ascorbate~0.35–0.6%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationEvens skin toneAnti-aging

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate

Ergothioneine~0.25–0.5%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine

Taraxacum officinale rhizome/root extract~0.2–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Taraxacum officinale rhizome/root extract

Arabidopsis thaliana extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-aging

Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking

More about Arabidopsis thaliana extract

Carnosine~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine

Camellia sinensis leaf extract~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Vitis vinifera seed extract~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract

Theobroma cacao seed extract~0.15–0.3%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Theobroma cacao seed extract

Curcuma longa root extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract

Olea europaea fruit extract~0.15–0.3%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit extract

Euterpe oleracea fruit extract~0.1–0.2%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that can have some anti-oxidant effect in skin

More about Euterpe oleracea fruit extract

Palmitoyl tripeptide-1~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Buddleja officinalis flower extract~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatoryAntibacterialAnti-oxidation

A plant flower extract that might help calm down inflammation in skin and neutralize free radicals, but evidence of effectiveness in skin is lacking

More about Buddleja officinalis flower extract

Coffea arabica seed extract~0.1–0.2%

Formula

Irritation risk: Low

Works for

Anti-oxidation

Might be helpful in neutralizing free radicals in skin

More about Coffea arabica seed extract

Crocus sativus flower extract~0.1–0.2%

Formula

Irritation risk: Low

More about Crocus sativus flower extract

Superoxide dismutase~0.15–0.25%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-oxidation

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase

Ubiquinone~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone

Plankton extract~0.15–0.25%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

Moisturizing

Can help attract water to the upper layer of the skin

More about Plankton extract

Micrococcus lysate~0.15–0.25%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-inflammatory

Consists of remains of dead bacteria cells. Is likely helpful in attracting water to the upper layer of the skin. Might be helpful in reducing inflammation and neutralizing free radicals in skin. It is claimed to be a "DNA repair enzyme"

More about Micrococcus lysate

Arginine~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Zingiber officinale root extract~0.05–0.15%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking

More about Zingiber officinale root extract

Ceramide np~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Ceramide ap~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

More about Ceramide ap

Ceramide eop~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

More about Ceramide eop

Linoleic acid~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

CleansingMoisturizingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid

Linolenic acid~0.25–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingCleansingReduces irritationAnti-inflammatory

An emollient that helps soften the skin and calm down inflammation

More about Linolenic acid

Ascorbic acid~0.15–0.3%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Bisabolol~0.15–0.25%

Formula

Irritation risk: Low

Works for

Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol

Tocopherol~0.15–0.3%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Tocopheryl acetate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Cholesterol~0.2–0.4%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol

Phytosphingosine~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine

Jojoba esters~0.2–0.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters

Sodium pca~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca

Methyl gluceth-20~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and soften it

More about Methyl gluceth-20

Glycerin~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Helianthus annuus seed cera~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Helianthus annuus seed cera

Acacia decurrens flower cera~0.2–0.4%

Key activeIrritant · high

Irritation risk: High

Works for

Moisturizing

Mimosa flower fax. Helps soften the upper layer of the skin. It adds a nice smell, but could be irritating

More about Acacia decurrens flower cera

Lecithin~0.25–0.45%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Sodium lauroyl lactylate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Sodium lauroyl lactylate

Dicetyl phosphate~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

More about Dicetyl phosphate

Propanediol dicaprylate/caprate~0.25–0.5%

Formula

Irritation risk: Low

More about Propanediol dicaprylate/caprate

Polyglycerin-3~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin

More about Polyglycerin-3

Ceteth-20 phosphate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Ceteth-20 phosphate

Diisostearyl malate~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

CleansingMoisturizing

Helps to soften the upper layer of the skin

More about Diisostearyl malate

Xanthan gum~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Steareth-2~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Steareth-2

Acacia senegal gum~0.25–0.4%

Irritant · medium

Irritation risk: Medium

Helps mask the small of other ingredients and improve the product texture

More about Acacia senegal gum

Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.2–0.4%

Formula

Irritation risk: Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate

Carbomer~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Acrylates/c10-30 alkyl acrylate crosspolymer~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Maltodextrin~0.2–0.4%

Formula

Irritation risk: Low

Works for

Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin

Ricinoleth-40~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

More about Ricinoleth-40

Sodium hydroxide~0.2–0.4%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Citric acid~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Sodium phytate~0.2–0.4%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Ethylhexylglycerin~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Phenoxyethanol~0.2–0.35%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Ethylhexyl palmitate~0.25–0.4%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

Alcohol~0.2–0.35%

Irritant · high

Irritation risk: High

Works for

Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol

Lactic acid~0.15–0.3%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Pentylene glycol~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Sorbitan isostearate~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Tribehenin~0.2–0.35%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin

Ingredient list view

Water, Butylene glycol, Propanediol, Ethylhexyl olivate, Cetearyl alcohol, Chlorogenic acids, Niacinamide, Lauryl lactate, Dimethyl isosorbide, Pyrroloquinoline quinone allyl ester, Hydrolyzed sodium hyaluronate, Glycyrrhiza glabra root extract, Tetrahexyldecyl ascorbate, Ergothioneine, Taraxacum officinale rhizome/root extract, Arabidopsis thaliana extract, Carnosine, Camellia sinensis leaf extract, Vitis vinifera seed extract, Theobroma cacao seed extract, Curcuma longa root extract, Olea europaea fruit extract, Euterpe oleracea fruit extract, Palmitoyl tripeptide-1, Buddleja officinalis flower extract, Coffea arabica seed extract, Crocus sativus flower extract, Superoxide dismutase, Ubiquinone, Plankton extract, Micrococcus lysate, Arginine, Zingiber officinale root extract, Ceramide np, Ceramide ap, Ceramide eop, Linoleic acid, Linolenic acid, Ascorbic acid, Bisabolol, Tocopherol, Tocopheryl acetate, Cholesterol, Phytosphingosine, Jojoba esters, Sodium pca, Methyl gluceth-20, Glycerin, Helianthus annuus seed cera, Acacia decurrens flower cera, Lecithin, Sodium lauroyl lactylate, Dicetyl phosphate, Propanediol dicaprylate/caprate, Polyglycerin-3, Ceteth-20 phosphate, Diisostearyl malate, Xanthan gum, Steareth-2, Acacia senegal gum, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Carbomer, Acrylates/c10-30 alkyl acrylate crosspolymer, Maltodextrin, Ricinoleth-40, Sodium hydroxide, Citric acid, Sodium phytate, Ethylhexylglycerin, Phenoxyethanol, Ethylhexyl palmitate, Alcohol, Lactic acid, Pentylene glycol, Sorbitan isostearate, Tribehenin

Compare prices

Retailers ranked by price — lowest first.

Find on Amazon

SkinBetter

Price unavailable

Check

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Skinbetter ScienceAlto Advanced Antioxidant DefenseYOUR PRODUCT	Daughters of MalayPost-Breakout Recovery Serum	ÉciatKeep Calm Soothing serum	AlgenistGenius Ultimate Anti-Aging Vitamin C+ Serum by Algenist
Match	—	81%	79%	78%
Price	—	—	—	$53.08
Shared key ingredients	—	8 of 26	8 of 26	8 of 26
Key difference	—	Alpha-Arbutin	Panthenol	3-O-Ethyl Ascorbic Acid
Irritancy	Medium	Low	Low	Medium
Drying alcohol	Contains drying alcohol	—	—	—
	View product	Shop	Shop	Shop

More alternatives: BIODANCE Hydro Cera-nol Ampoule Apothaka Skincare Barrier Support Serum

Cheaper alternatives? Browse formulas in the same category.

We compare ingredient profiles across our catalog — pick the closest match for your budget.

Open dupe finder

Product summary

"Skinbetter Science - Alto Advanced Antioxidant Defense" is effective for: Moisturizing, Anti-blemish, Anti-aging and Evens skin tone

Ingredient callouts

This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.15% - 0.30%) it cannot have a noticeable benefit for the skin.
Ceramides (phytosphingosine 0.20% - 0.35%, ceramide eop 0.15% - 0.30%, ceramide ap 0.15% - 0.25% and ceramide np 0.20% - 0.35%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
Peptides (palmitoyl tripeptide-1 0.15% - 0.25%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Humectants (polyglycerin-3 0.20% - 0.40%, glycerin 0.20% - 0.35%, sodium pca 0.15% - 0.30%, arginine 0.15% - 0.25% and carnosine 0.20% - 0.40%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 40 studies and safety reviews.

1
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
2
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
3
Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositionspatents.google.com
4
Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamagencbi.nlm.nih.gov
5
Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacysciencedirect.com
6
A comparison of the relative antioxidant potency of L‐ergothioneine and idebenoneonlinelibrary.wiley.com
7
l-Ergothioneine Protects Skin Cells against UV-Induced Damage—A Preliminary Studymdpi.com
8
Repair of Damaged DNA by Arabidopsis Cell Extractncbi.nlm.nih.gov
9
Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care productssciencedirect.com
10
Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmetics cir-safety.org
11
The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healingncbi.nlm.nih.gov
12
Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Updatecore.ac.uk
13
Vaughn, A. R., Branum, A., & Sivamani, R. K. (2016). Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research, 30(8), 1243–1264. doi:10.1002/ptr.5640ncbi.nlm.nih.gov
14
Total Oxidant Scavenging Capacity of Euterpe oleracea Mart. (Açaí) Seeds and Identification of Their Polyphenolic Compoundspubs.acs.org
15
Euterpe oleracea, Matricaria chamomilla, and Camellia sinensis as promising ingredients for development of skin care formulationssciencedirect.com
16
Saponins from the Flower Buds of Buddleja officinalispubs.acs.org
17
Anti-Inflammatory Effect of Buddleja officinalis on Vascular Inflammation in Human Umbilical Vein Endothelial Cellsworldscientific.com
18
Total Peroxynitrite Scavenging Capacity of Phenylethanoid and Flavonoid Glycosides from the Flowers of Buddleja officinalisjstage.jst.go.jp
19
Effect of green Coffea arabica L. seed oil on extracellular matrix components and water-channel expression in in vitro and ex vivo human skin modelsncbi.nlm.nih.gov
20
A novel efficient and safe treatment for atopic dermatitis: Topical superoxide dismutase (SOD).alliedacademies.org
21
Novel topical agent containing superoxide dismutase 100 000 IU and 4% of plant extracts as a mono-therapy for atopic dermatitispubmed.ncbi.nlm.nih.gov
22
Copper/Zinc Superoxide Dismutase in Human Skin: Current Knowledgefrontiersin.org
23
Photoprotective Effect of Topically Applied Superoxide Dismutase on Sunburn Reaction in Comparison with Sunscreenonlinelibrary.wiley.com
24
The role of superoxide dismutase (SOD) in skin disorderslink.springer.com
25
Topical formulations with superoxide dismutase: Influence of formulation composition on physical stability and enzymatic activityresearchgate.net
26
Skin protective effects of RM191A, a novel superoxide dismutase mimeticbiorxiv.org
27
Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent researchsciencedirect.com
28
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
29
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
30
Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory propertiesonlinelibrary.wiley.com
31
The Permeability Barrier in Essential Fatty Acid Deficiency: Evidence for a Direct Role for Linoleic Acid in Barrier Functionsciencedirect.com
32
Digital image analysis of the effect of topically applied linoleic acid on acne microcomedones.europepmc.org
33
α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammationresearchgate.net
34
Vitamin E in dermatologyncbi.nlm.nih.gov
35
Vitamin E and Skin Healthlpi.oregonstate.edu
36
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
37
5: Final Report on the Safety Assessment of Steareth-2,-4,-6,-7,-10,-11,-13,-15, and-20journals.sagepub.com
38
Safety Assessment of Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate as Used in Cosmeticscir-safety.org
39
Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
40
Dual Effects of Alpha-Hydroxy Acids on the Skinpdfs.semanticscholar.org

Skinbetter ScienceAlto Advanced Antioxidant Defense

Buy at SkinBetterCheck price Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at SkinBetterCheck price Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.