Dr Dennis Gross

Dr Dennis Gross DermInfusions Fill + Repair Serum

Name: Dr Dennis Gross - DermInfusions Fill + Repair Serum
Brand: Dr Dennis Gross

Efficacy100/100IrritancyHigh·

See all ingredients

Works for

Anti-aging

Niacinamide, Acetyl hexapeptide-8 + 11 more

Works well

What the product description says

“What it is: An alternative to injectable filler that visibly fills lines, plumps, and firms skin while restoring skin’s moisture barrier function for a more youthful complexion.”

Source: Sephora CA

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains bakuchiol, glycolic acid, lactobionic acid, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, centella asiatica extract, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, vitis vinifera seed extract.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.1–5%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.9–1.1%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.7–1.05%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.85%

BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.45–0.7%

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.6%

Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.3–0.5%

Lactobionic acidKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity~0.25–0.5%

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%

Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.6%

Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.55%

Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.25–0.45%

GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.2–0.4%

Moisturizing

Niacinamide, Acetyl hexapeptide-8 + 38 more

Works well

What the product description says

“What it is: An alternative to injectable filler that visibly fills lines, plumps, and firms skin while restoring skin’s moisture barrier function for a more youthful complexion.”

Source: Sephora CA

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, saccharide isomerate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide ap, ceramide eop, ceramide np, lactobionic acid, niacinamide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol, phytosphingosine

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.1–5%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.9–1.1%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.7–1.05%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.85%

Lactobionic acidHeroEffect: HighA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity~0.25–0.5%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.25–0.45%

Ceramide apHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%

Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.5%

PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~5.1–6.2%

EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~2.3–2.8%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~1.8–2.3%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~1.6–1.9%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~1.4–1.7%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~1.1–1.4%

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.4–0.6%

Saccharide isomerateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.35–0.65%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.55%

Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.6%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.55%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.3–0.6%

Diheptyl succinateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin and creates a nice product finish on the skin~0.3–0.5%

Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.25–0.45%

SphingolipidsKey active· EmollientEffect: HighSphingolipids are a group of lipids with a common chemical structure. Some of them are naturally present in skin and can be converted to ceramides~0.25–0.45%

Dimethicone crosspolymerKey activeEffect: MediumUsed to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface~0.25–0.5%

Capryloyl glycerin/sebacic acid copolymerKey activeEffect: MediumHelps soften the upper layer of the skin~0.25–0.5%

Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.2–0.4%

Superoxide dismutaseKey activeEffect: HighAn antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants~0.2–0.4%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.2–0.4%

Vitis vinifera fruit extractKey activeEffect: MediumA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.2–0.35%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3–3.6%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.3–0.55%

Butyrospermum parkii butterUnder-dosedA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.55%

Colloidal oatmealUnder-dosedHelps to restore skin barrier function, soften the upper layer of the skin and calm down inflammation~0.3–0.55%

Bifida ferment lysateUnder-dosedConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.25–0.45%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.25–0.5%

Anti-blemish

Side benefit · Niacinamide, Bakuchiol + 8 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

In addition, this product contains bakuchiol. It can help in reducing blemishes, even though it is less effective.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycolic acid, lactobionic acid, mandelic acid

Lactobionic acidKey activeEffect: MediumA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity~0.25–0.5%

Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%

Mandelic acidKey activeEffect: MediumHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid~0.25–0.5%

Centella asiatica extractEffect: LowA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.6%

PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%

Exfoliation

Side benefit · Lactobionic acid, Glycolic acid + 2 more

Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid, lactobionic acid, mandelic acid.

Mandelic acidKey activeEffect: HighHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid~0.25–0.5%

Evens skin tone

Side benefit · Niacinamide, Bakuchiol + 7 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: bakuchiol, glutathione, glycolic acid, lactobionic acid, mandelic acid, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Bifida ferment lysateEffect: Low, below effective doseConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.25–0.45%

Anti-oxidation

Side benefit · Bakuchiol, Glutathione + 13 more

Works well

This product contains antioxidants (bakuchiol, glutathione, lactobionic acid, superoxide dismutase, vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia sinensis leaf extract, centella asiatica extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.3–0.5%

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.3–0.6%

CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.25–0.45%

Terminalia ferdinandiana fruit extractEffect: LowA plant extract that might have some anti-oxidant effect in skin, but evidence is lacking~0.25–0.4%

Vitis vinifera fruit extractEffect: LowA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds~0.2–0.35%

Colloidal oatmealEffect: Low, below effective doseHelps to restore skin barrier function, soften the upper layer of the skin and calm down inflammation~0.3–0.55%

BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.2–0.35%

Bifida ferment lysateUnder-dosedConsists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect~0.25–0.45%

Can it cause trouble?

Irritancy

5 strong irritants: Arnica montana flower extract, Withania somnifera root extract + 3 more — patch-test recommended

High risk

We flagged 34 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Arnica montana flower extractA plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skinHigh~0.2–0.4%est.

Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.25–0.45%est.

Withania somnifera root extract—High~0.25–0.45%est.

Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.25–0.5%est.

Mandelic acidHelps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acidHigh~0.25–0.5%est.

Coco-glucosideUsed as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritatingHigh~0.35–0.65%est.

Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.35–0.6%est.

Jasminum officinale flower/leaf extractUsed as a fragranceHigh~0.15–0.3%est.

Eugenia caryophyllus flower extractA plant extract that is used as a fragrance. Can be irritatingHigh~0.2–0.35%est.

Lavandula angustifolia flower/leaf/stem extractUsed as a fragranceHigh~0.15–0.3%est.

Raspberry ketoneUsed as a fragrance. It can reduce skin pigmentation, but it is not safe to use for these purposes in high concentrations as use of raspberry ketone and its derivative is linked to causing loss of skin pigmentation in people (leukoderma)High~0.15–0.25%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~1.1–1.4%est.

BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.45–0.7%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.4–0.6%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.3–0.6%est.

Terminalia ferdinandiana fruit extractA plant extract that might have some anti-oxidant effect in skin, but evidence is lackingMedium~0.25–0.4%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.45%est.

Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.25–0.45%est.

Lactobionic acidA polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticityMedium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.25–0.5%est.

Lauryl glucosideHelps oil and water mix togetherMedium~0.35–0.6%est.

Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.25–0.5%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.3–0.55%est.

Sodium lauroyl lactylateHelps water and oil mix togetherMedium~0.25–0.5%est.

Potassium hydroxideUsed to adjust the pH level of productsMedium~0.25–0.5%est.

Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.25–0.5%est.

Benzyl glycolHelps dissolve other ingredients and preserve productsMedium~0.25–0.5%est.

Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.25–0.45%est.

Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.25–0.45%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.45%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.2–0.4%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.25–0.5%est.

Vitis vinifera fruit extractA plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seedsMedium~0.2–0.35%est.

Potassium sorbateA preservativeMedium~0.15–0.25%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.3–0.55%est.

Alternatives

Cheaper, or higher on efficacy

ISNTREE Hyper Retinol EX 1.0 Serum

Cheaper80% match

$13.71

Eqqualberry Bakuchiol Plumping Serum

Cheaper72% match

$16.74

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~5.1–6.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Niacinamide~4.1–5%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Butylene glycol~3–3.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Ectoin~2.3–2.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin

Sodium hyaluronate~1.8–2.3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hydrolyzed sodium hyaluronate~1.6–1.9%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Sodium acetylated hyaluronate~1.4–1.7%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Sodium hyaluronate crosspolymer~1.1–1.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Acetyl hexapeptide-8~0.9–1.1%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Palmitoyl tripeptide-1~0.7–1.05%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Palmitoyl tetrapeptide-7~0.6–0.85%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Oligopeptide-2~0.45–0.7%

Formula

Irritation risk: Low

More about Oligopeptide-2

Bakuchiol~0.45–0.7%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-inflammatoryAnti-blemishEvens skin toneAnti-aging

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol

Glutathione~0.4–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingAnti-oxidation

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Saccharide isomerate~0.35–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Saccharide isomerate

Camellia sinensis leaf extract~0.35–0.65%

Key active

Irritation risk: Low

Works for

AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Camellia sinensis leaf extract~0.3–0.6%

Key active

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingEvens skin toneAnti-blemishMoisturizing

More about Camellia sinensis leaf extract

Centella asiatica extract~0.3–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Vitis vinifera seed extract~0.3–0.5%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract

Sodium carboxymethyl beta-glucan~0.65–0.95%

Formula

Irritation risk: Low

Helps thicken the product formulation and create a gel-like texture

More about Sodium carboxymethyl beta-glucan

Inonotus obliquus extract~0.25–0.4%

Formula

Irritation risk: Low

More about Inonotus obliquus extract

Tetrahydrocurcumin~0.2–0.4%

Formula

Irritation risk: Low

More about Tetrahydrocurcumin

Ceramide np~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Ceramide ap~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

More about Ceramide ap

Ceramide eop~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

More about Ceramide eop

Phospholipids~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Sphingolipids~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Sphingolipids are a group of lipids with a common chemical structure. Some of them are naturally present in skin and can be converted to ceramides

More about Sphingolipids

Phytosphingosine~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine

Colloidal oatmeal~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationAnti-oxidation

Helps to restore skin barrier function, soften the upper layer of the skin and calm down inflammation

More about Colloidal oatmeal

Bisabolol~0.2–0.35%

Formula

Irritation risk: Low

Works for

Reduces irritationAnti-inflammatoryAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol

Superoxide dismutase~0.2–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-inflammatory

An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants

More about Superoxide dismutase

Terminalia ferdinandiana fruit extract~0.25–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant effect in skin, but evidence is lacking

More about Terminalia ferdinandiana fruit extract

Sodium pca~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca

Squalane~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Caffeine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Panthenol~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Butyrospermum parkii butter~0.3–0.55%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Aloe barbadensis leaf juice~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingAntibacterialReduces irritationReduces rednessAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice

Arnica montana flower extract~0.2–0.4%

Irritant · high

Irritation risk: High

A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin

More about Arnica montana flower extract

Acetyl glutamine~0.25–0.45%

Formula

Irritation risk: Low

More about Acetyl glutamine

Bifida ferment lysate~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Consists of remains of dead yeast bacteria cells. Helps to hydrate the skin and reduce irritation. Might has some anti-oxidant effect

More about Bifida ferment lysate

Chamomilla recutita flower extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract

Withania somnifera root extract~0.25–0.45%

Irritant · high

Irritation risk: High

More about Withania somnifera root extract

Glycolic acid~0.25–0.5%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid

Mandelic acid~0.25–0.5%

Key activeIrritant · high

Irritation risk: High

Works for

Evens skin toneExfoliationAnti-blemishAntibacterial

Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid

More about Mandelic acid

Lactobionic acid~0.25–0.5%

Hero · MoisturizingIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidationAnti-agingEvens skin toneExfoliationAnti-blemishAnti-inflammatory

A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity

More about Lactobionic acid

Ethylhexylglycerin~0.25–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Coco-glucoside~0.35–0.65%

Irritant · high

Irritation risk: High

Works for

Cleansing

Used as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating

More about Coco-glucoside

Lauryl glucoside~0.35–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Lauryl glucoside

Decyl glucoside~0.35–0.6%

Irritant · high

Irritation risk: High

Works for

Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside

Polyglyceryl-10 laurate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate

Diheptyl succinate~0.3–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and creates a nice product finish on the skin

More about Diheptyl succinate

Dimethicone~0.3–0.6%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Pentylene glycol~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Sodium lauroyl lactylate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Sodium lauroyl lactylate

Pvm/ma decadiene crosspolymer~0.25–0.5%

Formula

Irritation risk: Low

More about Pvm/ma decadiene crosspolymer

Vp/va copolymer~0.25–0.5%

Formula

Irritation risk: Low

Used to stabilize product formulation and create a nice product consistency

More about Vp/va copolymer

Xanthan gum~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Potassium hydroxide~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Used to adjust the pH level of products

More about Potassium hydroxide

Polysorbate 20~0.3–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Dimethicone crosspolymer~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface

More about Dimethicone crosspolymer

Carbomer~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Cholesterol~0.3–0.55%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol

Capryloyl glycerin/sebacic acid copolymer~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Capryloyl glycerin/sebacic acid copolymer

Leuconostoc/radish root ferment filtrate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate

Benzyl glycol~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients and preserve products

More about Benzyl glycol

Sodium lactate~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate

Sodium hydroxide~0.25–0.45%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Acetic acid~0.25–0.45%

Formula

Irritation risk: Low

More about Acetic acid

Tromethamine~0.25–0.45%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Sodium citrate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate

Citric acid~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Sodium metasilicate~0.25–0.45%

Formula

Irritation risk: Low

More about Sodium metasilicate

Gluconolactone~0.2–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

ExfoliationMoisturizingAnti-agingEvens skin toneAnti-blemishAnti-oxidation

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Tetrasodium glutamate diacetate~0.2–0.4%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate

Caprylic/capric triglyceride~0.25–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Jasminum officinale flower/leaf extract~0.15–0.3%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Jasminum officinale flower/leaf extract

Vitis vinifera fruit extract~0.2–0.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

A plant extract that helps attract water to the upper layer of the skin. It might be helpful in neutralizing free radicals in skin, but is less potent than the extract from the seeds

More about Vitis vinifera fruit extract

Eugenia caryophyllus flower extract~0.2–0.35%

Irritant · high

Irritation risk: High

A plant extract that is used as a fragrance. Can be irritating

More about Eugenia caryophyllus flower extract

Lavandula angustifolia flower/leaf/stem extract~0.15–0.3%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Lavandula angustifolia flower/leaf/stem extract

Sodium benzoate~0.15–0.3%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Raspberry ketone~0.15–0.25%

Irritant · high

Irritation risk: High

Used as a fragrance. It can reduce skin pigmentation, but it is not safe to use for these purposes in high concentrations as use of raspberry ketone and its derivative is linked to causing loss of skin pigmentation in people (leukoderma)

More about Raspberry ketone

Phenoxyethanol~0.15–0.25%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Potassium sorbate~0.15–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Ingredient list view

Water, Glycerin, Niacinamide, Butylene glycol, Ectoin, Sodium hyaluronate, Hydrolyzed sodium hyaluronate, Sodium acetylated hyaluronate, Sodium hyaluronate crosspolymer, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Oligopeptide-2, Bakuchiol, Glutathione, Saccharide isomerate, Camellia sinensis leaf extract, Camellia sinensis leaf extract, Centella asiatica extract, Vitis vinifera seed extract, Sodium carboxymethyl beta-glucan, Inonotus obliquus extract, Tetrahydrocurcumin, Ceramide np, Ceramide ap, Ceramide eop, Phospholipids, Sphingolipids, Phytosphingosine, Colloidal oatmeal, Bisabolol, Superoxide dismutase, Terminalia ferdinandiana fruit extract, Sodium pca, Squalane, Caffeine, Panthenol, Butyrospermum parkii butter, Aloe barbadensis leaf juice, Arnica montana flower extract, Acetyl glutamine, Bifida ferment lysate, Chamomilla recutita flower extract, Withania somnifera root extract, Glycolic acid, Mandelic acid, Lactobionic acid, Ethylhexylglycerin, Coco-glucoside, Lauryl glucoside, Decyl glucoside, Polyglyceryl-10 laurate, Diheptyl succinate, Dimethicone, Pentylene glycol, Sodium lauroyl lactylate, Pvm/ma decadiene crosspolymer, Vp/va copolymer, Xanthan gum, Potassium hydroxide, Polysorbate 20, Dimethicone crosspolymer, Carbomer, Cholesterol, Capryloyl glycerin/sebacic acid copolymer, Leuconostoc/radish root ferment filtrate, Benzyl glycol, Sodium lactate, Sodium hydroxide, Acetic acid, Tromethamine, Sodium citrate, Citric acid, Sodium metasilicate, Gluconolactone, Tetrasodium glutamate diacetate, Caprylic/capric triglyceride, Jasminum officinale flower/leaf extract, Vitis vinifera fruit extract, Eugenia caryophyllus flower extract, Lavandula angustifolia flower/leaf/stem extract, Sodium benzoate, Raspberry ketone, Phenoxyethanol, Potassium sorbate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Dr Dennis GrossDermInfusions Fill + Repair SerumYOUR PRODUCT	ISNTREEHyper Retinol EX 1.0 Serum	EqqualberryBakuchiol Plumping Serum	GalenicumDermaHypemium Double Serum
Match	—	80%	72%	71%
Price	≈ $103.79	$13.71≈ −$90.08	$16.74≈ −$87.05	$31.34≈ −$72.45
Shared key ingredients	—	13 of 38	17 of 38	9 of 38
Key difference	—	Retinol	Nonapeptide-1	Salicylic Acid
Irritancy	High	Medium	High	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Dr Dennis Gross - DermInfusions Fill + Repair Serum" is effective for: Anti-aging, Moisturizing, Evens skin tone, Anti-blemish and Exfoliation

Ingredient callouts

A good concentration of Niacinamide (4.10% - 5.00%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
This product contains acids (gluconolactone 0.20% - 0.40%, lactobionic acid 0.25% - 0.50%, mandelic acid 0.25% - 0.50% and glycolic acid 0.25% - 0.50%). Their concentration is low, and they will not have a strong exfoliating effect. Instead, they work to support the skin natural acid mantle and to attract water (as humectants). PHAs (gluconolactone and lactobionic acid) especially are great for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
Bakuchiol in this product (the concentration is about 0.45% - 0.70%). Helps fight photodamage (wrinkles, elasticity loss and pigmentation) and can reduce clogged pores and blemishes. Bakuchiol is a compound extracted from a plant Babchi. It acts similar to retinoids, but with less irritation risk.
Ceramides (phytosphingosine 0.25% - 0.50%, ceramide eop 0.25% - 0.45%, ceramide ap 0.20% - 0.40% and ceramide np 0.25% - 0.50%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
Peptides (palmitoyl tetrapeptide-7 0.60% - 0.85%, palmitoyl tripeptide-1 0.70% - 1.05% and acetyl hexapeptide-8 0.90% - 1.10%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Humectants (sodium lactate 0.25% - 0.45%, sodium pca 0.20% - 0.40%, saccharide isomerate 0.35% - 0.65%, acetyl hexapeptide-8 0.90% - 1.10%, sodium hyaluronate crosspolymer 1.10% - 1.40%, sodium acetylated hyaluronate 1.40% - 1.70%, sodium hyaluronate 1.80% - 2.30% and glycerin 5.10% - 6.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

About the brand

According to Cruelty-Free Kitty "Dr Dennis Gross" is cruelty free and so is its parent company.

Price

The product retails for 95.00CA$ in Canada, from 75.00$ up to 101.00$ in the United States and from 78.00£ up to 605.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 70 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
3
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
4
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
5
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
6
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
7
Bakuchiol in the Management of Acne-affected Skinresearchgate.net
8
Prospective, randomized, double‐blind assessment of topical bakuchiol and retinol for facial photoageingonlinelibrary.wiley.com
9
A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trialncbi.nlm.nih.gov
10
Glutathione as a skin whitening agent: Facts, myths, evidence and controversiesijdvl.com
11
Glutathione for skin lightening: a regnant myth or evidence-based verity?ncbi.nlm.nih.gov
12
Glutathione for skin lightening for dermatologists and cosmetologistsijord.com
13
Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Modelmdpi.com
14
Centella asiatica in cosmetologyncbi.nlm.nih.gov
15
Triterpene Composition and Bioactivities of Centella asiatica mdpi.com
16
Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblastsonlinelibrary.wiley.com
17
Assessment report on Centella asiatica (L.) Urban, herbaema.europa.eu
18
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
19
The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trialliebertpub.com
20
Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmetics cir-safety.org
21
The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healingncbi.nlm.nih.gov
22
Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Updatecore.ac.uk
23
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
24
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
25
Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory propertiesonlinelibrary.wiley.com
26
The role of epidermal sphingolipids in dermatologic diseasesncbi.nlm.nih.gov
27
Mechanism of action and clinical benefits of colloidal oatmeal for dermatologic practicencbi.nlm.nih.gov
28
α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammationresearchgate.net
29
A novel efficient and safe treatment for atopic dermatitis: Topical superoxide dismutase (SOD).alliedacademies.org
30
Novel topical agent containing superoxide dismutase 100 000 IU and 4% of plant extracts as a mono-therapy for atopic dermatitispubmed.ncbi.nlm.nih.gov
31
Copper/Zinc Superoxide Dismutase in Human Skin: Current Knowledgefrontiersin.org
32
Photoprotective Effect of Topically Applied Superoxide Dismutase on Sunburn Reaction in Comparison with Sunscreenonlinelibrary.wiley.com
33
The role of superoxide dismutase (SOD) in skin disorderslink.springer.com
34
Topical formulations with superoxide dismutase: Influence of formulation composition on physical stability and enzymatic activityresearchgate.net
35
Skin protective effects of RM191A, a novel superoxide dismutase mimeticbiorxiv.org
36
The chemotherapeutic potential of Terminalia ferdinandiana: Phytochemistry and bioactivityncbi.nlm.nih.gov
37
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
38
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
39
Effects of Topical Arnica Gel on Post-Laser Treatment Bruisesonlinelibrary.wiley.com
40
Effects of microcurrent application alone or in combination with topical Hypericum perforatum L. and Arnica montana L. on surgically induced wound healing in Wistar ratsthieme-connect.com
41
The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.)onlinelibrary.wiley.com
42
Accelerated resolution of laser‐induced bruising with topical 20% arnica: a rater‐blinded randomized controlled trialonlinelibrary.wiley.com
43
Bifidobacterium longumlysate, a new ingredient forreactive skinonlinelibrary.wiley.com
44
Use of Probiotics for Dermal Applicationsresearchgate.net
45
Photoprotective and antiinflammatory effects of topical glycolic acidncbi.nlm.nih.gov
46
Glycolic acid peel therapy – a current reviewncbi.nlm.nih.gov
47
Dual Effects of Alpha-Hydroxy Acids on the Skinmdpi.com
48
Summary of mandelic acid for the improvement of skin conditionsnucelle.com
49
Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasmajournals.lww.com
50
Lactobionic acidmdedge.com
51
Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water lossonlinelibrary.wiley.com
52
Comparative evaluation of skin moisture after topical application of 10% and 30% lactobionic acidonlinelibrary.wiley.com
53
The use of polyhydroxy acids (PHAs) in photoaged skin
54
In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Responseresearchgate.net
55
Allergen of the Year—Alkyl Glucosidepracticeupdate.com
56
Ecofriendly surfactant is allergen of the yearmdedge.com
57
Dimethicone as a protective ingredient in topical medicationsjaad.org
58
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
59
Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
60
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acnencbi.nlm.nih.gov
61
The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoagingonlinelibrary.wiley.com
62
Applications of hydroxy acids: classification, mechanisms, and photoactivityncbi.nlm.nih.gov
63
The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative studydovepress.com
64
A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimenncbi.nlm.nih.gov
65
Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acidsonlinelibrary.wiley.com
66
An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patientsonlinelibrary.wiley.com
67
Aging Skin: Causes, Treatments, and Preventionsciencedirect.com
68
Clinical and cosmeceutical uses of hydroxyacidssciencedirect.com
69
Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Lightneostrata.neogen.gr
70
Tyrosinase-Catalyzed Oxidation of the Leukoderma-Inducing Agent Raspberry Ketone Produces (E)-4-(3-Oxo-1-butenyl)-1,2-benzoquinone: Implications for Melanocyte Toxicitypubs.acs.org

Dr Dennis GrossDermInfusions Fill + Repair Serum

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Buy at SpaceNK US≈ $103.79 $78.00as of 11/9 06:29 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.

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