Perricone MD Fan Favorite Signature Regimen
Works for
ExfoliationGlycolic acid, Copper gluconate + 2 moreWorks well
“One of our best face wash products, it features exfoliating alpha lipoic acid to soften, smooth and reduce the appearance of excess oil and enlarged pores.”
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.
CleansingSodium laureth sulfate, Lauryl glucoside + 14 moreCan be harsh
“This gentle facial cleanser quickly and effectively removes makeup, excess oil and debris while softening and conditioning.”
This product works by removing dirt and oil from the surface of the skin.
It contains the following cleansing agents that tend to be harsh on the skin: sodium laureth sulfate.
The following cleansing agents are typically mild, but still can cause an irritation or allergy for some people cocamidopropyl betaine.
Keep in mind that cleansing can disrupt the skin barrier, and most people do not need to cleanse their skin more than once per day.
Can it cause trouble?
Irritancy13 strong irritants: Benzophenone-4, Methylchloroisothiazolinone + 11 more — patch-test recommendedHigh risk
Comedogenic8 ingredients rated 2 or more on the 0–5 pore-clogging scale8 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Sodium laureth sulfate~9.3–11.4%
- Irritation risk
- High
- Comedogenicity
- 2/5
Works as a foaming cleansing agent
More about Sodium laureth sulfateLauryl glucoside~5–6.2%
Cocamidopropyl betaine~4.5–5.4%
- Irritation risk
- High
Helps water and oil mix together. Used as a cleansing ingredient. Could be an allergen
More about Cocamidopropyl betainePpg-2 hydroxyethyl coco/isostearamide~2.3–2.8%
Dimethyl mea~1.9–2.3%
- Irritation risk
- Low
Thioctic acid~1.5–1.9%
Magnesium aspartate~1.4–1.7%
- Irritation risk
- Low
Might be helpful in restoring skin barrier function and calm down inflammation in skin
More about Magnesium aspartateZinc gluconate~1.1–1.4%
- Irritation risk
- Medium
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
More about Zinc gluconateCopper gluconate~0.9–1.1%
- Irritation risk
- Medium
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
More about Copper gluconateCitric acid~0.65–1%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidSodium chloride~0.65–0.95%
- Irritation risk
- Low
Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures
More about Sodium chlorideDisodium edta~0.5–0.75%
Benzophenone-4~0.7–1.05%
- Irritation risk
- High
Sulisobenzone. A UV filter. Is typically used to improve the product stability under exposure to UV light. It is effective against both UVA and UVB rays. It can be used is larger concentrations as a sun protection ingredient for the skin, but can be irritating
More about Benzophenone-4Methylchloroisothiazolinone~0.00075–0.0015%
- Irritation risk
- High
A preservative. Is a frequent allergen in cosmetics
More about MethylchloroisothiazolinoneMethylisothiazolinone~0.00075–0.0015%
Parfum~0.4–0.6%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumWater~0.35–0.65%
Glycerin~0.35–0.65%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinIsopropyl palmitate~0.3–0.6%
- Irritation risk
- Medium
- Comedogenicity
- 3/5
Helps soften the upper layer of the skin and create a thicker product consistency
More about Isopropyl palmitateCetearyl alcohol~0.35–0.6%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholGlyceryl stearate~0.3–0.6%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearatePeg-100 stearate~0.35–0.65%
- Irritation risk
- Low
Helps oil and water mix togehter and creates a nice product texture
More about Peg-100 stearateButylene glycol~0.25–0.5%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolPhosphatidylcholine~0.25–0.5%
- Irritation risk
- Medium
Used to enhance the delivery of other ingredients
More about PhosphatidylcholineTetrahexyldecyl ascorbate~0.25–0.5%
- Irritation risk
- Medium
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
More about Tetrahexyldecyl ascorbateDimethyl mea~0.25–0.5%
- Irritation risk
- Low
Acetyl hexapeptide-8~0.25–0.45%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Palmitoyl tripeptide-1~0.3–0.55%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-1Tyrosine~0.25–0.45%
Glycolic acid~0.25–0.5%
- Irritation risk
- High
An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid
More about Glycolic acidHelianthus annuus seed oil~0.3–0.5%
- Irritation risk
- Low
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
More about Helianthus annuus seed oilMagnesium aspartate~0.25–0.45%
- Irritation risk
- Low
Might be helpful in restoring skin barrier function and calm down inflammation in skin
More about Magnesium aspartateZinc gluconate~0.3–0.5%
- Irritation risk
- Medium
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
More about Zinc gluconateRosmarinus officinalis leaf extract~0.25–0.5%
- Irritation risk
- High
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
More about Rosmarinus officinalis leaf extractCopper gluconate~0.3–0.5%
- Irritation risk
- Medium
Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing
More about Copper gluconateSodium hyaluronate~0.3–0.55%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateRetinyl palmitate~0.3–0.5%
- Irritation risk
- High
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
More about Retinyl palmitateEchium plantagineum seed oil~0.3–0.5%
- Irritation risk
- Medium
A plant oil that because of its high content of alpha-linolenic acid help support skin barrier function and moisturize the skin
More about Echium plantagineum seed oilHydrolyzed myrtus communis leaf extract~0.3–0.55%
- Irritation risk
- High
Copper tripeptide-1~0.3–0.5%
- Irritation risk
- Low
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
More about Copper tripeptide-1Dimethicone~0.35–0.65%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeDisodium edta~0.3–0.55%
Carbomer~0.3–0.55%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerCeteareth-20~0.4–0.65%
- Irritation risk
- Medium
- Comedogenicity
- 2/5
Helps oil and water mix together. Has some emollient properties
More about Ceteareth-20Cyclopentasiloxane~0.3–0.6%
- Irritation risk
- Low
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
More about CyclopentasiloxaneCaprylyl glycol~0.3–0.6%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolCetearyl alcohol~0.35–0.6%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholCyclohexasiloxane~0.3–0.6%
- Irritation risk
- Low
A silicone that serves as an emollient. Helps create a nice non-greasy feels
More about CyclohexasiloxanePolysorbate 20~0.3–0.6%
Zea mays oil~0.25–0.5%
- Irritation risk
- Low
- Comedogenicity
- 3/5
A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function
More about Zea mays oilPhenoxyethanol~0.3–0.55%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolSorbic acid~0.3–0.55%
Water~0.3–0.55%
Ethylhexyl palmitate~0.3–0.6%
- Irritation risk
- Low
- Comedogenicity
- 3/5
An emollient that helps soften the skin and create a nice product texture
More about Ethylhexyl palmitateGlycerin~0.3–0.6%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinAleurites moluccanus seed oil~0.3–0.5%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Aleurites moluccanus seed oilPolyacrylamide~0.3–0.6%
- Irritation risk
- Medium
Used to improve product texture and help oil and water mix together
More about PolyacrylamideCetearyl alcohol~0.35–0.6%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholC13-14 isoparaffin~0.3–0.6%
- Irritation risk
- Low
Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency
More about C13-14 isoparaffinPolysorbate 60~0.3–0.6%
Glyceryl stearate~0.35–0.65%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearatePeg-100 stearate~0.4–0.65%
- Irritation risk
- Low
Helps oil and water mix togehter and creates a nice product texture
More about Peg-100 stearateDimethyl mea~0.3–0.55%
- Irritation risk
- Low
Tetrahexyldecyl ascorbate~0.3–0.55%
- Irritation risk
- Medium
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
More about Tetrahexyldecyl ascorbateTyrosine~0.3–0.5%
Hydrolyzed wheat protein~0.3–0.5%
- Irritation risk
- Medium
Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten
More about Hydrolyzed wheat proteinTocopheryl acetate~0.3–0.55%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetateHydrolyzed wheat starch~0.25–0.5%
- Irritation risk
- Low
Citric acid~0.25–0.5%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidPeg/ppg-18/18 dimethicone~0.3–0.55%
- Irritation risk
- Low
A silicone that mixes with water creating nice light-weight product texture
More about Peg/ppg-18/18 dimethiconeDimethicone~0.3–0.6%
- Irritation risk
- Low
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
More about DimethiconeCaprylyl glycol~0.3–0.5%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolLaureth-7~0.25–0.45%
Hexylene glycol~0.2–0.4%
- Irritation risk
- Medium
Helps create a more spreadable product texture
More about Hexylene glycolPhenoxyethanol~0.2–0.35%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolParfum~0.15–0.25%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumCitronellol~0.1–0.2%
Geraniol~0.1–0.2%
Hydroxycitronellal~0.1–0.25%
- Irritation risk
- High
A fragrance. A likely allergen and can be irritating
More about HydroxycitronellalButylphenyl methylpropional~0.1–0.2%
- Irritation risk
- High
A fragrance. Can trigger allergic reactions and be irritating
More about Butylphenyl methylpropionalBenzyl benzoate~0.05–0.1%
- Irritation risk
- High
Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating
More about Benzyl benzoateEugenol~0.05–0.1%
Ingredient list view
Water, Sodium laureth sulfate, Lauryl glucoside, Cocamidopropyl betaine, Ppg-2 hydroxyethyl coco/isostearamide, Dimethyl mea, Thioctic acid, Magnesium aspartate, Zinc gluconate, Copper gluconate, Citric acid, Sodium chloride, Disodium edta, Benzophenone-4, Methylchloroisothiazolinone, Methylisothiazolinone, Parfum, Water, Glycerin, Isopropyl palmitate, Cetearyl alcohol, Glyceryl stearate, Peg-100 stearate, Butylene glycol, Phosphatidylcholine, Tetrahexyldecyl ascorbate, Dimethyl mea, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Unknown, Tyrosine, Glycolic acid, Helianthus annuus seed oil, Magnesium aspartate, Zinc gluconate, Rosmarinus officinalis leaf extract, Copper gluconate, Sodium hyaluronate, Retinyl palmitate, Echium plantagineum seed oil, Hydrolyzed myrtus communis leaf extract, Copper tripeptide-1, Dimethicone, Disodium edta, Carbomer, Ceteareth-20, Cyclopentasiloxane, Caprylyl glycol, Cetearyl alcohol, Cyclohexasiloxane, Polysorbate 20, Zea mays oil, Phenoxyethanol, Sorbic acid, Water, Ethylhexyl palmitate, Glycerin, Aleurites moluccanus seed oil, Polyacrylamide, Cetearyl alcohol, C13-14 isoparaffin, Polysorbate 60, Glyceryl stearate, Peg-100 stearate, Dimethyl mea, Tetrahexyldecyl ascorbate, Tyrosine, Hydrolyzed wheat protein, Tocopheryl acetate, Hydrolyzed wheat starch, Citric acid, Peg/ppg-18/18 dimethicone, Dimethicone, Caprylyl glycol, Laureth-7, Hexylene glycol, Phenoxyethanol, Parfum, Citronellol, Geraniol, Hydroxycitronellal, Butylphenyl methylpropional, Benzyl benzoate, Eugenol
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Perricone MDFan Favorite Signature RegimenYOUR PRODUCT | OngredientsSkin Barrier Moisture Deep Cleanser | MuradMini AHA/BHA Exfoliating Cleanser | YEOUTHVitamin C Facial Cleanser Day/Night Cream | |
|---|---|---|---|---|
| Match | — | 48% | 44% | 42% |
| Price | $175.00 | $10.27−$164.73 | $19.00−$156.00 | $41.90−$133.10 |
| Shared key ingredients | — | 8 of 35 | 2 of 35 | 8 of 35 |
| Key difference | — | Tripeptide-1 | Salicylic Acid | Sodium Ascorbyl Phosphate |
| Irritancy | High | Medium | Low | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Replenix Glycolic Acid Resurfacing CleanserGlytone Mild Cream Cleanser
Product summary
"Perricone MD - Fan Favorite Signature Regimen" is effective for: Evens skin tone, Anti-aging, Exfoliation and Moisturizing
Ingredient callouts
- this product includes a form of Retinoids (vitamin A) - retinyl palmitate 0.30% - 0.50%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
- Peptides (copper tripeptide-1 0.30% - 0.50%, palmitoyl tripeptide-1 0.30% - 0.55% and acetyl hexapeptide-8 0.25% - 0.45%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Humectants (glycerin 0.30% - 0.60%, sodium hyaluronate 0.30% - 0.55%, glycerin 0.35% - 0.65% and acetyl hexapeptide-8 0.25% - 0.45%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Price
The product retails for 175.00$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 39 studies and safety reviews.
- 1Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
- 2
- 3Zinc salts in dermatologyncbi.nlm.nih.gov
- 4
- 5
- 6
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