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Product summary

"Noble Panacea - The Absolute Dawn-to-Dusk Moisturizer" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Noble Panacea - The Absolute Dawn-to-Dusk Moisturizer ticks this box. Acetyl hexapeptide-8, biosaccharide gum-1, glycerin, sodium hyaluronate and trehalose in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide ng, helianthus annuus extract, jojoba esters, nigella sativa seed oil and sesamum indicum seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This product also contains vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.10% - 0.45%) it cannot have a noticeable benefit for the skin.
  • This moisturizer contains an effective form of retinoids (vitamin A): retinol 0.10% - 0.40% and retinol 0.15% - 0.50%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
  • As a plus, this moisturizer also contains ceramides (ceramide ng 0.15% - 0.65% and ceramide ng 0.10% - 0.50%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • We like that this moisturizer contains peptides (sh-oligopeptide-2 0.10% - 0.40%, sh-oligopeptide-1 0.10% - 0.40%, palmitoyl tripeptide-38 0.10% - 0.40%, acetyl tetrapeptide-2 0.10% - 0.40%, palmitoyl tripeptide-38 0.10% - 0.40%, acetyl tetrapeptide-2 0.10% - 0.40% and acetyl hexapeptide-8 0.10% - 0.40%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.