Natura Bissé

Natura Bissé Inhibit High Definition Serum

Name: Natura Bissé - Inhibit High Definition Serum
Brand: Natura Bissé

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Niacinamide, Panthenol + 47 more

Works well

What the product description says

“This complex of highly concentrated ingredients includes Copper, Collagen Peptides and a Dermafill Complex-III which combines triple Hyaluronic Acid, Panthenol, Amaranth Oil, Mango and Shea Butter, Aquaxyl and Niacinamide to hydrate, revitalise and renew the skin.”

Source: Lookfantastic

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: anhydroxylitol, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl octapeptide-3, copper heptapeptide-14 pantothenate, dipeptide diaminobutyroyl benzylamide diacetate, heptapeptide-15 palmitate, niacinamide, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol, sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11, sh-polypeptide-59, sh-polypeptide-9, tripeptide-1, tripeptide-10 citrulline

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1–1.3%

Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Heptapeptide-15 palmitateHero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Acetyl octapeptide-3Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Tripeptide-10 citrullineHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Copper heptapeptide-14 pantothenateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-oligopeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-polypeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-polypeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Sh-polypeptide-59HeroEffect: High~0.1–0.15%

Sh-polypeptide-9HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~2.3–2.8%

Pentaerythrityl tetracaprylate/tetracaprateKey active· Emollient, OcclusiveEffect: HighAn emollient that helps soften the skin~2–2.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.6–2%

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~0.75–1.15%

Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.4–0.6%

XylitylglucosideKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrier function~0.25–0.45%

AnhydroxylitolKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrir function~0.25–0.45%

Mangifera indica seed butterKey activeEffect: HighHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.25–0.5%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.15–0.25%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.25%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.15–0.25%

DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.15–0.25%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.15–0.3%

DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.15–0.3%

GlucoseKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function~0.15–0.25%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.1–0.2%

Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.1–0.15%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.1–0.15%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.1–0.2%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.1–0.2%

Hydrolyzed soy proteinKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.1–0.2%

Hydrolyzed wheat proteinKey active· HumectantEffect: MediumCan help attract water to the upper layer of the skin. Avoid if sensitive to gluten~0.1–0.15%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.4–1.7%

Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.2–0.35%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.15–0.25%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.25%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.15–0.3%

Polyglyceryl-10 stearateEffect: LowHelps water and oil mix together and softens the upper layer of the skin~0.15–0.25%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~0.1–0.2%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.15–0.25%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.2%

Butyrospermum parkii butterUnder-dosedA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.6–0.9%

Avena sativa kernel extractUnder-dosedAn effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties~0.1–0.2%

Anti-aging

Niacinamide, Tripeptide-1 + 15 more

Works well

What the product description says

“Discover the anti-ageing power of the Natura Bissé Inhibit Exclusive High Definition Serum.”

Source: Lookfantastic

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains heptapeptide-15 palmitate, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl octapeptide-3, copper heptapeptide-14 pantothenate, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11, sh-polypeptide-59, sh-polypeptide-9, tripeptide-1, tripeptide-10 citrulline.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~4.2–5.1%

Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%

Heptapeptide-15 palmitateKey activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Tripeptide-10 citrullineKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Copper heptapeptide-14 pantothenateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Acetyl octapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-oligopeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-polypeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Sh-polypeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Sh-polypeptide-59Key activeEffect: Medium~0.1–0.15%

Sh-polypeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.6–0.9%

Anti-blemish

Side benefit · Niacinamide, Rosmarinus officinalis leaf extract

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Rosmarinus officinalis leaf extractUnder-dosedCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.05–0.15%

Evens skin tone

Side benefit · Niacinamide, Hydrolyzed soy protein

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Hydrolyzed soy proteinEffect: LowHelps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing~0.1–0.2%

Can it cause trouble?

Irritancy

10 strong irritants: Rosmarinus officinalis leaf extract, Parfum + 8 more — patch-test recommended

High risk

We flagged 27 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.05–0.15%est.

PhenylpropanolHelps mask the smell of other ingredients and helps preserve the product formulationHigh~0.1–0.2%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.15%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.1–0.2%est.

GeraniolA fragrance. Can be irritatingHigh~0.1–0.2%est.

HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.1–0.2%est.

LinaloolA fragrance. Can be irritatingHigh~0.1–0.2%est.

CitronellolA fragrance. Can be irritatingHigh~0.1–0.2%est.

Cinnamyl alcohol—High~0.1–0.2%est.

CitralA fragrance with a lemon scent. A likely irritantHigh~0.1–0.15%est.

Benzyl benzoateFragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritatingHigh~0.1–0.15%est.

Ci 19140A yellow dyeHigh~0.05–0.1%est.

C12-20 acid peg-8 esterHelps oil and water mix togetherMedium~5.8–7.1%est.

Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.1–0.15%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.1–0.15%est.

Hydrolyzed wheat proteinCan help attract water to the upper layer of the skin. Avoid if sensitive to glutenMedium~0.1–0.15%est.

Cetyl phosphateHelps oil and water mix togetherMedium~0.15–0.25%est.

Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.1–0.15%est.

Disodium edtaStabilizes the product formulationMedium~0.1–0.2%est.

Benzotriazolyl dodecyl p-cresolUsed to stabilize the product formulation protecting it from sun lightMedium~0.1–0.2%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.25%est.

Polyglyceryl-10 stearateHelps water and oil mix together and softens the upper layer of the skinMedium~0.15–0.25%est.

1,2-hexanediolA preservativeMedium~0.15–0.25%est.

Polyvinyl alcoholHelps improve the product textureMedium~0.15–0.3%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.15–0.3%est.

EthylhexylglycerinA preservativeMedium~0.15–0.25%est.

TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.15–0.25%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.6–0.9%est.

Alternatives

Cheaper, or higher on efficacy

Hanskin Collagen Peptide Hydra Ampoule

Cheaper73% match

$22.37

Medicube Hyaluronic Multi Peptide Serum

Cheaper71% match

$20.35

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

C12-20 acid peg-8 ester~5.8–7.1%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about C12-20 acid peg-8 ester

Niacinamide~4.2–5.1%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingAnti-blemishEvens skin toneMoisturizingReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Propanediol~3.1–3.8%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Betaine~2.3–2.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Pentaerythrityl tetracaprylate/tetracaprate~2–2.5%

Key active

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin

More about Pentaerythrityl tetracaprylate/tetracaprate

Glycerin~1.6–2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Glyceryl stearate~1.4–1.7%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Panthenol~1–1.3%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Cyclopentasiloxane~0.75–1.15%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Butyrospermum parkii butter~0.6–0.9%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Amaranthus caudatus seed extract~0.4–0.65%

Formula

Irritation risk: Low

More about Amaranthus caudatus seed extract

Hydrolyzed collagen~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen

Mangifera indica seed butter~0.25–0.5%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Helps to soften the upper layer of the skin and might have some anti-oxidant effect

More about Mangifera indica seed butter

Xylitylglucoside~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitylglucoside

Anhydroxylitol~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrir function

More about Anhydroxylitol

C10-30 cholesterol/lanosterol esters~0.25–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

More about C10-30 cholesterol/lanosterol esters

Xylitol~0.2–0.35%

Formula

Irritation risk: Low

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitol

Acetyl glutamine~0.15–0.3%

Formula

Irritation risk: Low

More about Acetyl glutamine

Arginine~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Sodium hyaluronate~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hydrolyzed sodium hyaluronate~0.1–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Sodium acetylated hyaluronate~0.1–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Helianthus annuus seed oil~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Sh-oligopeptide-1~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1

Sh-oligopeptide-2~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-2

Sh-polypeptide-1~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-1

Sh-polypeptide-9~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-9

Sh-polypeptide-11~0.1–0.2%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-11

Bacillus/folic acid ferment filtrate extract~0.1–0.15%

Formula

Irritation risk: Low

More about Bacillus/folic acid ferment filtrate extract

Acetyl octapeptide-3~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl octapeptide-3

Sh-polypeptide-59~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

More about Sh-polypeptide-59

Copper heptapeptide-14 pantothenate~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Copper heptapeptide-14 pantothenate

Heptapeptide-15 palmitate~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Heptapeptide-15 palmitate

Rosmarinus officinalis leaf extract~0.05–0.15%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract

Tocopherol~0.1–0.2%

Formula

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Sodium lactate~0.1–0.15%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate

Dipeptide diaminobutyroyl benzylamide diacetate~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate

Avena sativa kernel extract~0.1–0.2%

Under-dosed

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatoryReduces rednessAnti-oxidation

An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties

More about Avena sativa kernel extract

Sodium hyaluronate crosspolymer~0.1–0.15%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Pseudoalteromonas ferment extract~0.1–0.15%

Formula

Irritation risk: Low

More about Pseudoalteromonas ferment extract

Palmitoyl tripeptide-1~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Hydrolyzed wheat protein~0.1–0.15%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten

More about Hydrolyzed wheat protein

Hydrolyzed soy protein~0.1–0.2%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin toneAnti-oxidationAnti-inflammatory

Helps attract water to the upper layer of the skin. Might have some anti-aging, anti-oxidant, and skin lightening properties, but solid evidence is missing

More about Hydrolyzed soy protein

Palmitoyl tetrapeptide-7~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Tripeptide-10 citrulline~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-10 citrulline

Tripeptide-1~0.15–0.25%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1

Dimethicone~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Cetyl phosphate~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Cetyl phosphate

Dimethiconol~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol

Sodium acrylates copolymer~0.1–0.15%

Irritant · medium

Irritation risk: Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer

Lecithin~0.15–0.25%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Hydrogenated polydecene~0.1–0.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Disodium edta~0.1–0.2%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Benzotriazolyl dodecyl p-cresol~0.1–0.2%

Irritant · medium

Irritation risk: Medium

Used to stabilize the product formulation protecting it from sun light

More about Benzotriazolyl dodecyl p-cresol

Caprylyl glycol~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Octadecyl di-t-butyl-4-hydroxyhydrocinnamate~0.15–0.25%

Formula

Irritation risk: Low

More about Octadecyl di-t-butyl-4-hydroxyhydrocinnamate

Phospholipids~0.1–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Polyglyceryl-10 stearate~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps water and oil mix together and softens the upper layer of the skin

More about Polyglyceryl-10 stearate

Decylene glycol~0.1–0.2%

Formula

Irritation risk: Low

Used to creat a nice product texture and support penetration of other ingredients

More about Decylene glycol

Silica~0.25–0.45%

Formula

Irritation risk: Low

Used to absorb oil and can temporarily mattify skin

More about Silica

Butylene glycol~0.15–0.25%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

1,2-hexanediol~0.15–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Xanthan gum~0.15–0.25%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Glyceryl caprylate~0.2–0.35%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate

Polyvinyl alcohol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Helps improve the product texture

More about Polyvinyl alcohol

Lactic acid/glycolic acid copolymer~0.1–0.2%

Formula

Irritation risk: Low

More about Lactic acid/glycolic acid copolymer

Octoxynol-9~0.15–0.25%

Formula

Irritation risk: Low

Works for

Cleansing

More about Octoxynol-9

Dextran~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran

Polysorbate 20~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Carbomer~0.15–0.25%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Pentylene glycol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Ethylhexylglycerin~0.15–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Phenylpropanol~0.1–0.2%

Irritant · high

Irritation risk: High

Helps mask the smell of other ingredients and helps preserve the product formulation

More about Phenylpropanol

Glucose~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function

More about Glucose

Triethanolamine~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine

Phenoxyethanol~0.15–0.3%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Parfum~0.1–0.15%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Limonene~0.1–0.2%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Geraniol~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Geraniol

Hydroxycitronellal~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal

Linalool~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Citronellol~0.1–0.2%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Citronellol

Cinnamyl alcohol~0.1–0.2%

Irritant · high

Irritation risk: High

More about Cinnamyl alcohol

Citral~0.1–0.15%

Irritant · high

Irritation risk: High

A fragrance with a lemon scent. A likely irritant

More about Citral

Benzyl benzoate~0.1–0.15%

Irritant · high

Irritation risk: High

Fragrance with sweet balsamic smell. Help to preserve products and dissolve other ingredients. Could trigger allergic reactions and be irritating

More about Benzyl benzoate

Titanium dioxide~0.2–0.4%

Formula

Irritation risk: Low

Works for

Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide

Mica~0.1–0.2%

Formula

Irritation risk: Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica

Caramel~0.05–0.1%

Formula

Irritation risk: Low

More about Caramel

Ci 19140~0.05–0.1%

Irritant · high

Irritation risk: High

A yellow dye

More about Ci 19140

Ingredient list view

Water, C12-20 acid peg-8 ester, Niacinamide, Propanediol, Betaine, Pentaerythrityl tetracaprylate/tetracaprate, Glycerin, Glyceryl stearate, Panthenol, Cyclopentasiloxane, Butyrospermum parkii butter, Amaranthus caudatus seed extract, Hydrolyzed collagen, Mangifera indica seed butter, Xylitylglucoside, Anhydroxylitol, C10-30 cholesterol/lanosterol esters, Xylitol, Acetyl glutamine, Arginine, Sodium hyaluronate, Hydrolyzed sodium hyaluronate, Sodium acetylated hyaluronate, Helianthus annuus seed oil, Sh-oligopeptide-1, Sh-oligopeptide-2, Sh-polypeptide-1, Sh-polypeptide-9, Sh-polypeptide-11, Bacillus/folic acid ferment filtrate extract, Acetyl octapeptide-3, Sh-polypeptide-59, Copper heptapeptide-14 pantothenate, Heptapeptide-15 palmitate, Rosmarinus officinalis leaf extract, Tocopherol, Sodium lactate, Dipeptide diaminobutyroyl benzylamide diacetate, Avena sativa kernel extract, Sodium hyaluronate crosspolymer, Pseudoalteromonas ferment extract, Palmitoyl tripeptide-1, Hydrolyzed wheat protein, Hydrolyzed soy protein, Palmitoyl tetrapeptide-7, Tripeptide-10 citrulline, Tripeptide-1, Dimethicone, Cetyl phosphate, Dimethiconol, Sodium acrylates copolymer, Lecithin, Hydrogenated polydecene, Disodium edta, Benzotriazolyl dodecyl p-cresol, Caprylyl glycol, Octadecyl di-t-butyl-4-hydroxyhydrocinnamate, Phospholipids, Polyglyceryl-10 stearate, Decylene glycol, Silica, Butylene glycol, 1,2-hexanediol, Xanthan gum, Glyceryl caprylate, Polyvinyl alcohol, Lactic acid/glycolic acid copolymer, Octoxynol-9, Dextran, Polysorbate 20, Carbomer, Pentylene glycol, Ethylhexylglycerin, Phenylpropanol, Glucose, Triethanolamine, Phenoxyethanol, Parfum, Limonene, Geraniol, Hydroxycitronellal, Linalool, Citronellol, Cinnamyl alcohol, Citral, Benzyl benzoate, Titanium dioxide, Mica, Caramel, Ci 19140

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Natura BisséInhibit High Definition SerumYOUR PRODUCT	HanskinCollagen Peptide Hydra Ampoule	MedicubeHyaluronic Multi Peptide Serum	Centellian24Lifting Peptide Serum
Match	—	73%	71%	70%
Price	$799.00	$22.37−$776.63	$20.35−$778.65	$19.23−$779.77
Shared key ingredients	—	16 of 36	10 of 36	13 of 36
Key difference	—	Pentapeptide-18	Acetyl Tetrapeptide-3	Dipeptide-2
Irritancy	High	Medium	Medium	High
Drying alcohol	—	—	—	Contains drying alcohol
	View product	Shop	Shop	Shop

More alternatives: fromrier EGF Hyper-Active Bubble Ampoule MEDI-PEEL Peptide 9 Aqua Essence Lifting Ampoule

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 34 studies and safety reviews.

1
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
2
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
3
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
4
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
5
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
6
Extraction and Characteristics of Seed Kernel Oil from Mangopdfs.semanticscholar.org
7
Promising features of mango (Mangifera indica L.) kernel oil: a reviewncbi.nlm.nih.gov
8
Evaluation of the fatty acid composition of the seeds of Mangifera indica L. and their applicationncbi.nlm.nih.gov
9
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
10
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
11
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
12
Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
13
Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
14
Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
15
Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
16
Allergic contact dermatitis induced by rosemary leaf extract in a cleansing gelpubmed.ncbi.nlm.nih.gov
17
Safety Assessment of Rosmarinus officinalis (Rosemary)-Derived Ingredients as Used in Cosmeticsjournals.sagepub.com
18
Rosmarinus officinalis Extract Suppresses Propionibacterium acnes–Induced Inflammatory Responsesliebertpub.com
19
Vitamin E in dermatologyncbi.nlm.nih.gov
20
Vitamin E and Skin Healthlpi.oregonstate.edu
21
Wheat in skin caremdedge.com
22
Extracts from Glycine max (soybean) induce elastin synthesis and inhibit elastase activityonlinelibrary.wiley.com
23
Dermatological and cosmeceutical benefits of Glycine max (soybean) and its active componentsncbi.nlm.nih.gov
24
Safety Assessment of Soy Peptides as Used in Cosmeticscir-safety.org
25
Dimethicone as a protective ingredient in topical medicationsjaad.org
26
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
27
Safety Assessment of Alkyl Phosphates as Used in Cosmeticscir-safety.org
28
Final Report on the Safety Assessment of Acrylates Copolymer and 33 Related Cosmetic Ingredientsjournals.sagepub.com
29
Safety Assessment of Polyene Group as Used in Cosmeticscir-safety.org
30
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmeticscir-safety.org
31
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
32
Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Functionncbi.nlm.nih.gov
33
Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extractsec.europa.eu
34
Analysis of Dyes in Cosmetics: Challenges and Recent Developmentsmdpi.com

Natura BisséInhibit High Definition Serum

Buy at Bluemercury$799.00 $799.00as of 11/11 00:28 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Bluemercury$799.00 $799.00as of 11/11 00:28 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.