kineff

kineff Dermacycle 102 Night Renewal Cream

Name: kineff - Dermacycle 102 Night Renewal Cream
Brand: kineff

Efficacy100/100IrritancyMedium

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Works for

1 of 1 advertised claim delivered

Moisturizing

Copper tripeptide-1, Ceramide np + 41 more

Strong evidence

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, arginine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide np, copper tripeptide-1, niacinamide, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.5–3.1%

Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.3–0.55%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.9–6%

TyrosineKey activeEffect: High~0.3–0.55%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.3–0.55%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.4–0.6%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.4–0.6%

Carthamus tinctorius seed oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and might help calm down inflammation~0.4–0.6%

CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.3–0.55%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.7–1%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.4–5.4%

Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.3–0.55%

Aspartic acidKey active· HumectantEffect: HighAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.3–0.55%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.25–0.5%

AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.3–0.55%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%

IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.3–0.55%

Lysine hclKey activeEffect: High~0.3–0.55%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.5–1.8%

Oenothera biennis oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can support skin barrier function~0.4–0.6%

Oryza sativa bran oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and might have some anti-oxidant properties~0.5–0.8%

Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Persea gratissima fruit extractKey active· EmollientEffect: High~0.4–0.65%

Prunus amygdalus dulcis seed extractKey activeEffect: HighAlmond extract (oil) - helps soften the upper layer of the skin~0.35–0.6%

SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.55%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.5%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.4–0.65%

ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.55%

Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~0.15–0.3%

Hydrogenated poly(c6-14 olefin)Key active· EmollientEffect: MediumHelps soften the upper layer of the skin and create a nice product texture~4.9–6%

ProlineKey activeEffect: Medium~0.3–0.6%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%

Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.4–0.65%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.4–0.65%

Oryza sativa germ oilKey active· EmollientEffect: Medium~0.5–0.8%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.2–1.5%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.3–0.55%

Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~1.9–2.3%

Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.9–1.1%

Avena sativa kernel extractUnder-dosedEffect: HighAn effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties~0.5–0.75%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.5–0.75%

Anti-oxidation

Not advertised by the brand · Carnosine, Tocotrienols + 12 more

Strong evidence

This product contains antioxidants (carnosine, tocotrienols) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - creatine, melatonin also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.3–0.55%

TocotrienolsKey activeEffect: HighA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.55–0.85%

MelatoninKey activeEffect: MediumA compound that can regulate sleep cycles in humans and animals. When used in cosmetics, comes from plant sources. It can work as anti-oxidant in skin when applied topically in skincare~0.35–0.6%

CreatineKey activeEffect: MediumCan support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness~0.3–0.55%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%

Carthamus tinctorius seed oilEffect: LowAn emollient that helps soften the skin and might help calm down inflammation~0.4–0.6%

Arctium lappa root extractEffect: LowPlant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating~0.3–0.55%

Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.3–0.55%

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.4–5.4%

Oenothera biennis oilEffect: LowHelps soften the upper layer of the skin and can support skin barrier function~0.4–0.6%

Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.3–0.55%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.5–0.75%

Sodium ascorbyl phosphateUnder-dosedEffect: MediumA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.3–0.55%

Avena sativa kernel extractEffect: Low, below effective doseAn effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties~0.5–0.75%

Anti-aging

Not advertised by the brand · Adenosine, Niacinamide + 17 more

Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, aspartic acid, carnosine, copper tripeptide-1, creatine, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, serine, threonine, tocotrienols.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.5–1.8%

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%

CreatineKey activeEffect: MediumCan support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness~0.3–0.55%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.3–0.55%

CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.3–0.55%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Aspartic acidKey activeEffect: MediumAn amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles~0.3–0.55%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%

TocotrienolsKey activeEffect: MediumA type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms~0.55–0.85%

ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.55%

SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.55%

MelatoninEffect: LowA compound that can regulate sleep cycles in humans and animals. When used in cosmetics, comes from plant sources. It can work as anti-oxidant in skin when applied topically in skincare~0.35–0.6%

Sodium ascorbyl phosphateEffect: Low, below effective doseA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.3–0.55%

Evens skin tone

Not advertised by the brand · Niacinamide, Alanine + 1 more

Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.3–0.55%

Anti-blemish

Not advertised by the brand · Niacinamide, Beta-glucan + 2 more

Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Oenothera biennis oilEffect: LowHelps soften the upper layer of the skin and can support skin barrier function~0.4–0.6%

Sodium ascorbyl phosphateUnder-dosedEffect: HighA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.3–0.55%

Can it cause trouble?

Irritancy

8 flagged ingredients

Medium risk

We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.3–0.55%est.

Arctium lappa root extractPlant extract. Has some anti-microbial and anti-oxidant properties. Can be irritatingHigh~0.3–0.55%est.

MethylpropanediolHelps dissolve other ingredients in a formulationMedium~3–3.6%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.5–3.1%est.

1,2-hexanediolA preservativeMedium~0.7–1.1%est.

Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.3–0.55%est.

Oenothera biennis oilHelps soften the upper layer of the skin and can support skin barrier functionMedium~0.4–0.6%est.

EthylhexylglycerinA preservativeMedium~0.25–0.45%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~4.4–5.4%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.4–0.65%est.

Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~0.15–0.3%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Hydrolyzed collagen extract~25–31%

Formula

Irritation risk: Low

More about Hydrolyzed collagen extract

Hydrogenated poly(c6-14 olefin)~4.9–6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about Hydrogenated poly(c6-14 olefin)

Glycerin~4.9–6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Butyrospermum parkii butter~4.4–5.4%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Methylpropanediol~3–3.6%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol

Caprylic/capric triglyceride~2.5–3.1%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Dicaprylyl ether~1.9–2.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether

Niacinamide~1.5–1.8%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-blemishEvens skin toneReduces irritationReduces rednessAntibacterialAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Butylene glycol~1.2–1.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

1,2-hexanediol~0.7–1.1%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Behenyl alcohol~0.9–1.1%

Formula

Irritation risk: Low

Works for

Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol

Dimethicone~0.7–1%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Tocotrienols~0.55–0.85%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-aging

A type of vitamin E that is more powerful in neutralizing free radicals compared to its other forms

More about Tocotrienols

Tocopherol~0.5–0.75%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Oryza sativa bran oil~0.5–0.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and might have some anti-oxidant properties

More about Oryza sativa bran oil

Oryza sativa germ oil~0.5–0.8%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Oryza sativa germ oil

Avena sativa kernel extract~0.5–0.75%

Under-dosed

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-oxidation

An effective moisturizing and skin barrier repair ingredient. Helps calm down inflammation and has some anti-oxidant properties

More about Avena sativa kernel extract

Goat milk extract~0.35–0.65%

Formula

Irritation risk: Low

More about Goat milk extract

Persea gratissima fruit extract~0.4–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Persea gratissima fruit extract

Prunus amygdalus dulcis seed extract~0.35–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Almond extract (oil) - helps soften the upper layer of the skin

More about Prunus amygdalus dulcis seed extract

Melatonin~0.35–0.6%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-aging

A compound that can regulate sleep cycles in humans and animals. When used in cosmetics, comes from plant sources. It can work as anti-oxidant in skin when applied topically in skincare

More about Melatonin

Ascorbic acid~0.3–0.55%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-oxidationEvens skin toneAnti-aging

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Riboflavin~0.3–0.55%

Formula

Irritation risk: Low

More about Riboflavin

Sodium ascorbyl phosphate~0.3–0.55%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate

Proline~0.3–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Proline

Alanine~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine

Arginine~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Aspartic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps increase skin hydration and might help to slightly improve skin firmness, potentially reducing lines and wrinkles

More about Aspartic acid

Cysteine hcl~0.3–0.55%

Formula

Irritation risk: Low

More about Cysteine hcl

Glutamic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid

Glutamine~0.3–0.55%

Formula

Irritation risk: Low

More about Glutamine

Isoleucine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine

Leucine~0.3–0.55%

Formula

Irritation risk: Low

More about Leucine

Lysine hcl~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Lysine hcl

Methionine~0.3–0.55%

Formula

Irritation risk: Low

More about Methionine

Ornithine hcl~0.3–0.55%

Formula

Irritation risk: Low

More about Ornithine hcl

Serine~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine

Threonine~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine

Tryptophan~0.3–0.55%

Formula

Irritation risk: Low

More about Tryptophan

Tyrosine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Tyrosine

Valine~0.3–0.55%

Formula

Irritation risk: Low

More about Valine

Acetyl hexapeptide-8~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Copper tripeptide-1~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Palmitoyl pentapeptide-4~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4

Palmitoyl tetrapeptide-7~0.4–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Palmitoyl tripeptide-1~0.4–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Adenosine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Ceramide np~0.4–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Arctium lappa root extract~0.3–0.55%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Plant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating

More about Arctium lappa root extract

Beta-glucan~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryReduces irritationMoisturizingAnti-oxidationAnti-agingAnti-blemish

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan

Carnosine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine

Carthamus tinctorius seed oil~0.4–0.6%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the skin and might help calm down inflammation

More about Carthamus tinctorius seed oil

Creatine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-aging

Can support skin's ability to neutralize free radicals and produce collagen, though further research is needed to confirm effectiveness

More about Creatine

Oenothera biennis oil~0.4–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-blemishAnti-oxidationAnti-inflammatory

Helps soften the upper layer of the skin and can support skin barrier function

More about Oenothera biennis oil

Squalane~0.4–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Cholesterol~0.4–0.6%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol

Cetyl alcohol~0.4–0.65%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol

Water~0.25–0.5%

Formula

Irritation risk: Low

Plain old water

More about Water

Sodium hyaluronate~0.25–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Cetearyl alcohol~0.4–0.65%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Hydrogenated lecithin~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Polysorbate 20~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Sorbitan isostearate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Ethylhexylglycerin~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Glycolipids~0.25–0.45%

Formula

Irritation risk: Low

More about Glycolipids

Phytosteryl/behenyl/octyldodecyl lauroyl glutamate~0.25–0.45%

Formula

Irritation risk: Low

More about Phytosteryl/behenyl/octyldodecyl lauroyl glutamate

Xanthan gum~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Hydrogenated polyisobutene~0.3–0.55%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Glyceryl stearate se~0.15–0.3%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se

Trisodium edta~0.15–0.25%

Formula

Irritation risk: Low

Helps preserve product formulations

More about Trisodium edta

Ingredient list view

Hydrolyzed collagen extract, Hydrogenated poly(c6-14 olefin), Glycerin, Butyrospermum parkii butter, Methylpropanediol, Caprylic/capric triglyceride, Dicaprylyl ether, Niacinamide, Butylene glycol, 1,2-hexanediol, Behenyl alcohol, Dimethicone, Tocotrienols, Tocopherol, Oryza sativa bran oil, Oryza sativa germ oil, Avena sativa kernel extract, Goat milk extract, Persea gratissima fruit extract, Prunus amygdalus dulcis seed extract, Melatonin, Ascorbic acid, Riboflavin, Sodium ascorbyl phosphate, Proline, Alanine, Arginine, Aspartic acid, Cysteine hcl, Glutamic acid, Glutamine, Isoleucine, Leucine, Lysine hcl, Methionine, Ornithine hcl, Serine, Threonine, Tryptophan, Tyrosine, Valine, Acetyl hexapeptide-8, Copper tripeptide-1, Palmitoyl pentapeptide-4, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Adenosine, Ceramide np, Arctium lappa root extract, Beta-glucan, Carnosine, Carthamus tinctorius seed oil, Creatine, Oenothera biennis oil, Squalane, Cholesterol, Cetyl alcohol, Water, Sodium hyaluronate, Cetearyl alcohol, Hydrogenated lecithin, Polysorbate 20, Sorbitan isostearate, Ethylhexylglycerin, Glycolipids, Phytosteryl/behenyl/octyldodecyl lauroyl glutamate, Xanthan gum, Hydrogenated polyisobutene, Glyceryl stearate se, Trisodium edta

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	kineffDermacycle 102 Night Renewal CreamYOUR PRODUCT	TIRTIRMatcha Calming Cream 50ml	AbibYesStyle Exclusive PDRN Volume Fill-it Booster Crème 2.5 Tube Mini 5pcs Bundle Set	AHCEye Cream For Face
Match	—	78%	78%	77%
Price	$12.99	$23.14+$10.15	$37.53+$24.54	$14.75+$1.76
Shared key ingredients	—	14 of 36	13 of 36	23 of 36
Key difference	—	Dipeptide-2	Retinal	Acetyl Dipeptide-1 Cetyl Ester
Irritancy	Medium	Medium	Medium	High
Drying alcohol	—	—	—	Contains drying alcohol
	View product	Shop	Shop	Shop

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Product summary

"kineff - Dermacycle 102 Night Renewal Cream" has a good moisturizing formula. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (acetyl hexapeptide-8, alanine, arginine, aspartic acid and carnosine) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide np, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, carthamus tinctorius seed oil and cholesterol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.30% - 0.55%) it cannot have a noticeable benefit for the skin.
Another benefit is that this moisturizer contain ceramides (ceramide np 0.40% - 0.60%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
We like that this moisturizer contains peptides (palmitoyl tripeptide-1 0.40% - 0.60%, palmitoyl tetrapeptide-7 0.40% - 0.60%, palmitoyl pentapeptide-4 0.30% - 0.55%, copper tripeptide-1 0.30% - 0.55% and acetyl hexapeptide-8 0.30% - 0.55%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.30% - 0.55%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: oatmeal extract, sodium ascorbyl phosphate, vitamin c and vitamin e

Irritation risk

There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 51 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
3
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
4
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
5
Dimethicone as a protective ingredient in topical medicationsjaad.org
6
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
7
Safety Assessment of Tocopherols and Tocotrienols as Used in Cosmeticsjournals.sagepub.com
8
Tocotrienol‐rich fraction attenuates UV‐induced inflammaging: A bench to bedside studyonlinelibrary.wiley.com
9
Tocotrienols: Vitamin E beyond tocopherolssciencedirect.com
10
Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)onlinelibrary.wiley.com
11
Tocotrienols: the unsaturated sidekick shifting new paradigms in vitamin E therapeuticspdfs.semanticscholar.org
12
Vitamin E in dermatologyncbi.nlm.nih.gov
13
Vitamin E and Skin Healthlpi.oregonstate.edu
14
Study on the Composition of Rice Bran Oil and Its Higher Free Fatty Acids Valuelink.springer.com
15
[Melatonin in dermatology. Experimental and clinical aspects]researchgate.net
16
Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgarisncbi.nlm.nih.gov
17
Sodium ascorbyl phosphate in topical microemulsionssciencedirect.com
18
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmeticseuropepmc.org
19
Regulation of collagen synthesis in human dermal fibroblasts by the sodium and magnesium salts of ascorbyl-2-phosphatekarger.com
20
Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatmentonlinelibrary.wiley.com
21
Application of l-ascorbic acid and its derivatives (sodium ascorbyl phosphate and magnesium ascorbyl phosphate) in topical cosmetic formulations: stability studiesinis.iaea.org
22
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trialonlinelibrary.wiley.com
23
Combination of amino acids reduces pigmentation in B16F0 melanoma cellsncbi.nlm.nih.gov
24
Acetyl aspartic acid, a novel active ingredient, demonstrates potential to improve signs of skin ageing: from consumer need to clinical proofncbi.nlm.nih.gov
25
In vivo topical application of acetyl aspartic acid increases fibrillin-1 and collagen IV deposition leading to a significant improvement of skin firmnessncbi.nlm.nih.gov
26
Local rhamnosoft, ceramides and L‐isoleucine in atopic eczema: a randomized, placebo controlled trialonlinelibrary.wiley.com
27
Topical palmitoyl pentapeptide provides improvement in photoaged human facial skinonlinelibrary.wiley.com
28
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
29
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
30
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
31
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com
32
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
33
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
34
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
35
Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – part 1: Achillea millefolium–Curcuma longaonlinelibrary.wiley.com
36
β-Glucans: Multi-Functional Modulator of Wound Healingncbi.nlm.nih.gov
37
Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucanonlinelibrary.wiley.com
38
Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Reviewonlinelibrary.wiley.com
39
Anticancer properties of low molecular weight oat beta-glucan – An in vitro studysciencedirect.com
40
A critical review on production and industrial applications 2 of beta-glucanssciencedirect.com
41
Improving skin function with CM-glucan, a biological response modifier from yeastonlinelibrary.wiley.com
42
Preparation, characterization, and biological properties of β-glucansncbi.nlm.nih.gov
43
Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatusncbi.nlm.nih.gov
44
Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care productssciencedirect.com
45
Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjectsncbi.nlm.nih.gov
46
Folic acid and creatine improve the firmness of human skin in vivoncbi.nlm.nih.gov
47
The Creatine Kinase System in Human Skin: Protective Effects of Creatine Against Oxidative and UV Damage In Vitro and In Vivosciencedirect.com
48
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
49
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
50
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
51
Final report on the safety assessment of EDTA, calcium disodium EDTA, diammonium EDTA, dipotassium EDTA, disodium EDTA, TEA-EDTA, tetrasodium EDTA, tripotassium EDTA, trisodium EDTA, HEDTA, and trisodium HEDTAncbi.nlm.nih.gov

kineffDermacycle 102 Night Renewal Cream

Buy on Amazon$12.99 · as of 10/30 06:23 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$12.99 · as of 10/30 06:23 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.