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Product summary

Based on the ingredients included, "kineff - Dermacycle 102 Night Renewal Cream" works well for moisturizing the skin. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Acetyl hexapeptide-8, alanine, arginine, aspartic acid and carnosine in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (ceramide np, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, carthamus tinctorius seed oil and cholesterol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.30% - 0.55%) it cannot have a noticeable benefit for the skin.
  • Another benefit is that this moisturizer contain ceramides (ceramide np 0.40% - 0.60%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • We like that this moisturizer contains peptides (palmitoyl tripeptide-1 0.40% - 0.60%, palmitoyl tetrapeptide-7 0.40% - 0.60%, palmitoyl pentapeptide-4 0.30% - 0.55%, copper tripeptide-1 0.30% - 0.55% and acetyl hexapeptide-8 0.30% - 0.55%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.30% - 0.55%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: sodium ascorbyl phosphate, vitamin c, oatmeal extract and vitamin e

Irritation risk

There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.