PRODUCT REVIEW
ISDIN Melaclear Advanced
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Product summary
What can the product work for?
Anti-aging
gluconolactone
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
niacinamide
2.3% -
2.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
tocopherol
0.4% -
0.6%
Irritation risk:
Concentration: Insufficient!
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Evens skin tone
What does the product description say?
Daily use reduces dark spots with notable results as early as two weeks and remarkable results within 12 weeks.
gluconolactone
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
mandelic acid
0.55% -
0.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid
niacinamide
2.3% -
2.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
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Exfoliation
mandelic acid
0.55% -
0.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid
gluconolactone
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
salicylic acid
0.3% -
0.6%
Irritation risk:
Concentration: Insufficient!
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
Anti-blemish
niacinamide
2.3% -
2.8%
Irritation risk:
Concentration: Effectiveness: HIGH
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
gluconolactone
4.1% -
5%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
mandelic acid
0.55% -
0.8%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Helps shed the upper layer of dead cells from the surface of the skin revealing smoother, brighter skin. It can help to reduce hyperpigmentation. It has anti-bacterial properties, and might help to reduce blemishes, as well as fine lines and wrinkles. It is considered to be gentler than glycolic acid
Show more
Moisturizing
gluconolactone
4.1% -
5%
Irritation risk:
Concentration: Effectiveness: HIGH
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
peg-10 dimethicone
0.25% -
0.5%
Irritation risk:
Concentration: Effectiveness: HIGH
A silicone that works to soften the upper layer of the skin and reduce its water loss
saccharide isomerate
0.5% -
0.75%
Irritation risk:
Concentration: Effectiveness: HIGH
Helps attract water to the upper layer of the skin
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Anti-oxidation
gluconolactone
4.1% -
5%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
tocopherol
0.4% -
0.6%
Irritation risk:
Concentration: Insufficient!
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
tocopheryl acetate
0.3% -
0.55%
Irritation risk:
Concentration: Insufficient!
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Exfoliation | |
| Evens skin tone |
Total Promises Fulfilled score:
100/100.
Buy now
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 0
Potential irritants
alcohol denat.
1.6% -
2%
Irritation risk:
Produces temporary toning effect. Can help dissolve other ingredients or preserve products
cocoglycerides
1.2% -
1.5%
Irritation risk:
Works for:
Cleansing,
Moisturizing
Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin
Show more
Comodogenic ingredients
No comodogenic ingredients detected
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| WIMJ similarity score |
72%
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81%
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78%
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78%
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| Irritancy | IRRITANCY
HIGH
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MEDIUM
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MEDIUM
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MEDIUM
| IRRITANCY
HIGH
| IRRITANCY
HIGH
| IRRITANCY
HIGH
| IRRITANCY
MEDIUM
| IRRITANCY
HIGH
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HIGH
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MEDIUM
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HIGH
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Ingredients & concentrations
All ingredients
Key Actives
niacinamide
2.3% -
2.8%
Irritation risk:
Works for:
Anti-blemish,
Anti-aging,
Moisturizing,
Evens skin tone,
Reduces irritation,
Reduces redness,
Antibacterial,
Anti-inflammatory
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture.
The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
gluconolactone
4.1% -
5%
Irritation risk:
Works for:
Anti-aging,
Moisturizing,
Evens skin tone,
Exfoliation,
Anti-oxidation,
Anti-blemish
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Show more
Potential irritants
alcohol denat.
1.6% -
2%
Irritation risk:
Produces temporary toning effect. Can help dissolve other ingredients or preserve products
cocoglycerides
1.2% -
1.5%
Irritation risk:
Works for:
Cleansing,
Moisturizing
Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin
Show more
Comodogenic ingredients
We couldn't find any comodogenic ingredients in this product
All ingredients
propanediol
5.2% -
6.4%
Irritation risk:
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
gluconolactone
4.1% -
5%
Irritation risk:
Works for:
Anti-aging,
Moisturizing,
Evens skin tone,
Exfoliation,
Anti-oxidation,
Anti-blemish
A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals
Show more
Ingredient list view
Water, Propanediol, Gluconolactone, Dimethicone, Niacinamide, Tranexamic acid, Alcohol denat., Phytic acid, Cocoglycerides, Silica, Polyacrylate crosspolymer-6, C9-12 alkane, Mandelic acid, Saccharide isomerate, Sodium hydroxide, Hydrogenated lecithin, Dipotassium glycyrrhizate, Parfum, Tocopherol, Salicylic acid, Dimethicone/vinyl dimethicone crosspolymer, 4-butylresorcinol, Polysilicone-11, Tocopheryl acetate, Sclareolide, Sodium metabisulfite, Xanthan gum, Sodium benzoate, Peg-10 dimethicone, Disodium edta, T-butyl alcohol, Citric acid, Sodium citrate, Ci 15985, Ci 19140
Sources
- A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne
- The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoaging
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- The use of polyhydroxy acids (PHAs) in photoaged skin
- Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acids
- An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patients
- Aging Skin: Causes, Treatments, and Prevention
- Clinical and cosmeceutical uses of hydroxyacids
- Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Light
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
- Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin
- The amelioration effect of tranexamic acid in wrinkles induced by skin dryness
- Efficacy and possible mechanisms of topical tranexamic acid in melasma
- Cosmetic and dermatologic use of alpha hydroxy acids
- Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma
- Summary of mandelic acid for the improvement of skin conditions
- Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma
- Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model
- Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.
- Vitamin E in dermatology
- Vitamin E and Skin Health
- Salicylic acid as a peeling agent: a comprehensive review
- Beta Hydroxy Acids
- A review of toxicity from topical salicylic acid preparations
- Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Study
- Final report on the safety assessment of sodium sulfite, potassium sulfite, ammonium sulfite, sodium bisulfite, ammonium bisulfite, sodium metabisulfite and potassium metabisulfite
- Amended final report of the safety assessment of t-Butyl Alcohol as used in cosmetics