Medicube

Medicube Zero Pore One-day Serum

Name: Medicube - Zero Pore One-day Serum
Brand: Medicube

Efficacy100/100IrritancyMedium

See all ingredients

Works for

Exfoliation

Gluconolactone, Glycolic acid + 3 more

Works well

What the product description says

“Overnight resurfacing serum, formulated with 15.2% AHA + BHA + PHA Pore minimizing complex with all-in-one pore care solution (High efficacy, low irritation) > AHA 1% , 3 types of AHA combined for surface exfoliation > ... ; BHA 0.2% , Salicylic acid exfoliates deeply into pores > PHA 14% , A new generation of AHA, gentle peeling for sensitive skin Why medicube's Zero Pore One-day Serum?”

Source: N/A

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone, glycolic acid.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~4.7–5.8%

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.5%

Salicylic acidUnder-dosedUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.35–0.65%

Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.5%

Anti-aging

Gluconolactone, Niacinamide + 6 more

Works well

What the product description says

“Deals with all types of pores with different solutions 1) O-shaped pores Caused by excess sebum & blackheads Show more > > BHA helps reduce excess sebum and blackheads 2) U-shaped pores Caused by dry and dehydrated skin > PHA helps refill moisture on your skin 3) Y-shaped pores Caused by aging and loss of skin elasticity > Niacinamide helps improve pore elasticity Instant & cumulative pore refining results 1.”

Source: N/A

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, gluconolactone, glycolic acid, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: madecassoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%

MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.1–0.25%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.35%

Anti-blemish

Niacinamide, Gluconolactone + 4 more

Works well

What the product description says

“Zero Pore One-day Serum”

From product name

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: gluconolactone, glycolic acid

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.7%

GluconolactoneKey activeEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~4.7–5.8%

Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.5%

Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.2–0.35%

Evens skin tone

Gluconolactone, Niacinamide + 4 more

Works well

What the product description says

“Pore moisturizing care clinical results after one day of use Surface moisturization +3% Internal moisturization +1.3% Skin brightening +12% Weight 30ml Show more >”

Source: N/A

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone, glycolic acid, niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.1–0.25%

Salicylic acidEffect: Low, below effective doseUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.35–0.65%

Moisturizing

Niacinamide, Madecassoside + 19 more

Works well

What the product description says

“Deals with all types of pores with different solutions 1) O-shaped pores Caused by excess sebum & blackheads Show more > > BHA helps reduce excess sebum and blackheads 2) U-shaped pores Caused by dry and dehydrated skin > PHA helps refill moisture on your skin 3) Y-shaped pores Caused by aging and loss of skin elasticity > Niacinamide helps improve pore elasticity Instant & cumulative pore refining results 1.”

Source: N/A

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, pentylene glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide

MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.1–0.25%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3–3.7%

Polyglycerin-3Key active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~1.6–2%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.75–1.1%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.2–0.4%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.2–0.4%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.2–0.35%

Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.15–0.25%

Lactobacillus ferment lysateKey activeEffect: MediumA "broth" with parts of dead cells of lactobacteria. Might be helpful supporting diverse microbiome in skin, but evidence is lacking~0.1–0.15%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.55–0.8%

Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.25–0.45%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.25–0.45%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.4–0.6%

AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.5%

Anti-oxidation

Not advertised by the brand · Gluconolactone, Madecassoside + 2 more

Works well

This product contains antioxidants (madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - gluconolactone also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.1–0.25%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.4%

Can it cause trouble?

Irritancy

1 strong irritant: Gardenia florida fruit extract

Medium risk

We flagged 15 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.35–0.65%est.

Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.25–0.5%est.

Gardenia florida fruit extractUsed as a fragrance. Can be irritating.High~0.2–0.4%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~4.7–5.8%est.

MethylpropanediolHelps dissolve other ingredients in a formulationMedium~4.3–5.3%est.

1,2-hexanediolA preservativeMedium~0.7–1.05%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.95–1.15%est.

Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.35–0.65%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.25–0.45%est.

Sodium citrateHelps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve productsMedium~0.2–0.4%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.2–0.35%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.25–0.45%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.2–0.35%est.

MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.1–0.25%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

Cheaper, or higher on efficacy

Some By Mi AHA 10% Amino Peeling Ampoule

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JUMISO D-Panthenol Barrier Soothing Serum 70ml

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Ingredients

Filter by role to see what each ingredient is doing.

Zero pore one-day serum

Not recognized

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Gluconolactone~4.7–5.8%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-agingEvens skin toneExfoliationAnti-blemishAnti-oxidation

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Methylpropanediol~4.3–5.3%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol

Glycerin~3–3.7%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Propanediol~2.3–2.8%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Tromethamine~1.9–2.3%

Formula

Irritation risk: Low

Helps adjust pH in products

More about Tromethamine

Polyglycerin-3~1.6–2%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to attract water to the upper layer of the skin

More about Polyglycerin-3

Niacinamide~1.4–1.7%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

1,2-hexanediol~0.7–1.05%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Citric acid~0.95–1.15%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Dimethicone~0.75–1.1%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Butylene glycol~0.55–0.8%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

C12-14 pareth-12~0.5–0.75%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about C12-14 pareth-12

Hydroxyethylcellulose~0.5–0.7%

Formula

Irritation risk: Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose

Salicylic acid~0.35–0.65%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-blemishExfoliationAnti-inflammatoryAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid

Ammonium acryloyldimethyltaurate/vp copolymer~0.4–0.6%

Formula

Irritation risk: Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer

Sodium polyacryloyldimethyl taurate~0.35–0.65%

Irritant · medium

Irritation risk: Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate

Lecithin~0.4–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Allantoin~0.25–0.5%

Under-dosed

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Lactic acid~0.25–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Glycolic acid~0.25–0.5%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid

Ethylhexylglycerin~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Adenosine~0.25–0.4%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Dextrin~0.25–0.45%

Formula

Irritation risk: Low

Works for

Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin

Indigofera tinctoria extract~0.2–0.4%

Formula

Irritation risk: Low

More about Indigofera tinctoria extract

Sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Sodium citrate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps to control the skin's pH level. Maintains the skin's natural film of amino-lactic acids and oils. Helps to preserve products

More about Sodium citrate

Hemerocallis fulva flower extract~0.25–0.45%

Formula

Irritation risk: Low

More about Hemerocallis fulva flower extract

Gardenia florida fruit extract~0.2–0.4%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating.

More about Gardenia florida fruit extract

Hydrolyzed hyaluronic acid~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Hydrolyzed sodium hyaluronate~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Sodium hyaluronate crosspolymer~0.2–0.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Trisodium phosphate~0.2–0.35%

Formula

Irritation risk: Low

More about Trisodium phosphate

Myosotis sylvatica flower/leaf/stem extract~0.2–0.35%

Formula

Irritation risk: Low

More about Myosotis sylvatica flower/leaf/stem extract

Pentylene glycol~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Hydroxypropyltrimonium hyaluronate~0.15–0.3%

Formula

Irritation risk: Low

More about Hydroxypropyltrimonium hyaluronate

Sodium acetylated hyaluronate~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate

Centella asiatica extract~0.2–0.35%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Reduces irritationAnti-inflammatoryReduces rednessMoisturizingAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Madecassoside~0.1–0.25%

Hero · MoisturizingIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside

Lactobacillus ferment lysate~0.1–0.15%

Key active

Irritation risk: Low

Works for

Moisturizing

A "broth" with parts of dead cells of lactobacteria. Might be helpful supporting diverse microbiome in skin, but evidence is lacking

More about Lactobacillus ferment lysate

Taraxacum officinale leaf extract~0.1–0.15%

Formula

Irritation risk: Low

More about Taraxacum officinale leaf extract

Ingredient list view

Unknown, Water, Gluconolactone, Methylpropanediol, Glycerin, Propanediol, Tromethamine, Polyglycerin-3, Niacinamide, 1,2-hexanediol, Citric acid, Dimethicone, Butylene glycol, C12-14 pareth-12, Hydroxyethylcellulose, Salicylic acid, Ammonium acryloyldimethyltaurate/vp copolymer, Sodium polyacryloyldimethyl taurate, Lecithin, Allantoin, Lactic acid, Glycolic acid, Ethylhexylglycerin, Adenosine, Dextrin, Indigofera tinctoria extract, Sodium hyaluronate, Hyaluronic acid, Sodium citrate, Hemerocallis fulva flower extract, Gardenia florida fruit extract, Hydrolyzed hyaluronic acid, Hydrolyzed sodium hyaluronate, Sodium hyaluronate crosspolymer, Trisodium phosphate, Myosotis sylvatica flower/leaf/stem extract, Pentylene glycol, Hydroxypropyltrimonium hyaluronate, Sodium acetylated hyaluronate, Centella asiatica extract, Madecassoside, Lactobacillus ferment lysate, Taraxacum officinale leaf extract

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Medicube

$26.00

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MedicubeZero Pore One-day SerumYOUR PRODUCT	Some By MiAHA 10% Amino Peeling Ampoule	TOUN28AHA + BHA + PHA Serum	MEDI-PEELAHA BHA Alpha Arbutin Ampoule
Match	—	77%	77%	76%
Price	$26.00	$16.79−$9.21	$37.90+$11.90	—
Shared key ingredients	—	9 of 18	5 of 18	11 of 18
Key difference	—	Capryloyl Salicylic Acid	Panthenol	Vitamin C
Irritancy	Medium	Medium	Low	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Medicube - Zero Pore One-day Serum" is effective for: Exfoliation, Anti-aging, Anti-blemish, Evens skin tone and Moisturizing

Ingredient callouts

Exfoliating acids (glycolic acid 0.25% - 0.50% and lactic acid 0.25% - 0.50%). In this concentration, they will have a noticeable exfoliating effect. They can also have an anti-aging effect and stimulate collagen production in a long-run. PHAs (gluconolactone 4.70% - 5.80%) in this product also work for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
Adenosine 0.25% - 0.40%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - madecassoside 0.10% - 0.25% The Centella Asiatica Actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
Humectants (sodium acetylated hyaluronate 0.15% - 0.25%, sodium hyaluronate crosspolymer 0.20% - 0.35%, hydrolyzed hyaluronic acid 0.20% - 0.40%, hyaluronic acid 0.25% - 0.45%, sodium hyaluronate 0.25% - 0.45%, polyglycerin-3 1.60% - 2.00% and glycerin 3.00% - 3.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 54.00A$ in Australia and for 37.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 49 studies and safety reviews.

1
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acnencbi.nlm.nih.gov
2
The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoagingonlinelibrary.wiley.com
3
Applications of hydroxy acids: classification, mechanisms, and photoactivityncbi.nlm.nih.gov
4
The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative studydovepress.com
5
A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimenncbi.nlm.nih.gov
6
The use of polyhydroxy acids (PHAs) in photoaged skin
7
Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acidsonlinelibrary.wiley.com
8
An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patientsonlinelibrary.wiley.com
9
Aging Skin: Causes, Treatments, and Preventionsciencedirect.com
10
Clinical and cosmeceutical uses of hydroxyacidssciencedirect.com
11
Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Lightneostrata.neogen.gr
12
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
13
Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
14
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
15
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
16
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
17
Dimethicone as a protective ingredient in topical medicationsjaad.org
18
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
19
Salicylic acid as a peeling agent: a comprehensive reviewncbi.nlm.nih.gov
20
Beta Hydroxy Acidsfda.gov
21
A review of toxicity from topical salicylic acid preparationssciencedirect.com
22
Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Studyonlinelibrary.wiley.com
23
Profile of wound healing process induced by allantoinscielo.br
24
Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
25
Dual Effects of Alpha-Hydroxy Acids on the Skinpdfs.semanticscholar.org
26
Photoprotective and antiinflammatory effects of topical glycolic acidncbi.nlm.nih.gov
27
Glycolic acid peel therapy – a current reviewncbi.nlm.nih.gov
28
Dual Effects of Alpha-Hydroxy Acids on the Skinmdpi.com
29
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
30
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
31
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
32
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
33
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
34
Allergic contact dermatitis from gardenia fruitpubmed.ncbi.nlm.nih.gov
35
VOLATILE CONSTITUENTS AND BIOLOGICAL ACTIVITIES OF GARDENIA JASMINOIDES thaiscience.info
36
Acetylated Hyaluronic Acid: Enhanced Bioavailability and Biological Studieshindawi.com
37
Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Modelmdpi.com
38
Centella asiatica in cosmetologyncbi.nlm.nih.gov
39
Triterpene Composition and Bioactivities of Centella asiatica mdpi.com
40
Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblastsonlinelibrary.wiley.com
41
Assessment report on Centella asiatica (L.) Urban, herbaema.europa.eu
42
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
43
The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trialliebertpub.com
44
Centella asiatica in Dermatology: An Overviewonlinelibrary.wiley.com
45
Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytesncbi.nlm.nih.gov
46
Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stressonlinelibrary.wiley.com
47
Madecassoside Inhibits Melanin Synthesis by Blocking Ultraviolet-Induced Inflammationmdpi.com
48
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
49
Stability Study of the Active Constituents in the Centella asiatica Extract Formulationstandfonline.com

MedicubeZero Pore One-day Serum

Buy at Medicube$26.00 Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Medicube$26.00 Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.