Hydroxatone®

Hydroxatone® AM/PM Anti-wrinkle

Name: Hydroxatone® - AM/PM Anti-wrinkle
Brand: Hydroxatone®

Efficacy75/100IrritancyHigh

See all ingredients

Works for

Anti-aging

Palmitoyl oligopeptide, Acetyl hexapeptide-8 + 9 more

May help

What the product description says

“AM/PM Anti-wrinkle”

From product name

This product contains acetyl hexapeptide-8, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, vitis vinifera seed extract. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%

Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.3–0.5%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~4.5–5.5%

Algae extractEffect: LowPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.25–0.45%

Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.6–0.9%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.5%

Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.25–0.5%

Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.25–0.45%

Moisturizing

Side benefit · Palmitoyl oligopeptide, Panthenol + 19 more

Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: algae extract, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, algae extract.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, panthenol

Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.4–0.65%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.65%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%

C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~5–6.1%

Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~4.5–5.5%

Prunus amygdalus dulcis seedKey activeEffect: HighHelps soften the upper layer of the skin~3.2–3.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.4–3%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.1–2.5%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1–1.3%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.45–0.65%

Theobroma cacao seed butterKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect~0.4–0.6%

Algae extractKey active· Humectant, EmollientEffect: HighPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet~0.25–0.45%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.4–1.8%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.45–0.7%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.55%

Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.25–0.5%

Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.65–0.95%

Butyrospermum parkii butterUnder-dosedA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.6–0.9%

Anti-oxidation

Side benefit · Vitis vinifera seed extract, Punica granatum extract + 10 more

Works well

This product contains antioxidants (vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - punica granatum extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.3–0.5%

Punica granatum extractKey activeEffect: MediumA plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective~0.25–0.5%

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~4.5–5.5%

Theobroma cacao seed butterEffect: LowHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect~0.4–0.6%

Panax ginseng extractEffect: LowA plant extract that might have anti-oxidant properties. Can be irritating~0.25–0.5%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.15–0.25%

Echinacea angustifolia extractEffect: LowPlant extract that might contain antioxidants, have antibacterial effect and help reduce inflammation, but solid evidence is lacking. Can be irritating~0.1–0.15%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.3–0.55%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.55%

Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.5%

Can it cause trouble?

Irritancy

4 strong irritants: Retinyl palmitate, Dmdm hydantoin + 2 more — patch-test recommended

High risk

We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.25–0.45%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.25–0.5%est.

Dmdm hydantoinA preservative that releases formaldehyde and can be irritatingHigh~0.25–0.5%est.

Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.25–0.5%est.

Panax ginseng extractA plant extract that might have anti-oxidant properties. Can be irritatingHigh~0.25–0.5%est.

Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.2–0.4%est.

Rosa damascena flower—High~0.15–0.3%est.

Echinacea angustifolia extractPlant extract that might contain antioxidants, have antibacterial effect and help reduce inflammation, but solid evidence is lacking. Can be irritatingHigh~0.1–0.15%est.

Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.75–1.1%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.55%est.

Tetrasodium edtaHelps to stabilize the product formulationMedium~0.25–0.5%est.

TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.3–0.55%est.

BhtA preservativeMedium~0.25–0.5%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.55%est.

Sorbic acidA preservativeMedium~0.25–0.5%est.

Punica granatum extractA plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effectiveMedium~0.25–0.5%est.

Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.15–0.25%est.

Comedogenic

6 ingredients rated 2 or more on the 0–5 pore-clogging scale

6 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.6–0.9%est.

Theobroma cacao seed butterHelps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect3/5~0.4–0.6%est.

Theobroma cacao extract—3/5~0.3–0.55%est.

Algae extractPlant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet3/5~0.25–0.45%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1–1.3%est.

Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.75–1.1%est.

Alternatives

Cheaper, or higher on efficacy

Peter Thomas Roth Mega-Rich Intensive Anti-Aging Cellular Creme

Higher efficacy · 100/10056% match

$85.00

Bradceuticals CLASSIC MESENCHYMAL STEM CELL SERUM

Higher efficacy · 87/10051% match

$69.99

View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

C12-15 alkyl benzoate~5–6.1%

Key active

Irritation risk: Low

Works for

Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate

Prunus amygdalus dulcis oil~4.5–5.5%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil

Prunus amygdalus dulcis seed~3.2–3.9%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Prunus amygdalus dulcis seed

Glycerin~2.4–3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Dimethicone~2.1–2.5%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Sorbitan stearate~1.6–2%

Formula

Irritation risk: Low

Works for

Cleansing

Helps water and oil mix together

More about Sorbitan stearate

Glyceryl stearate~1.4–1.8%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Peg-100 stearate~1.2–1.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate

Cetearyl alcohol~1–1.3%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Ceteareth-20~0.75–1.1%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20

Butyrospermum parkii butter~0.6–0.9%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Stearic acid~0.65–0.95%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

Butylene glycol~0.45–0.7%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Acetyl hexapeptide-8~0.4–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Sodium hyaluronate~0.45–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Panthenol~0.4–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Theobroma cacao seed butter~0.4–0.6%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-dandruff

Helps soften the upper layer of the skin and can be helpful in restoring the skin barrier function. Might have some anti-oxidant effect

More about Theobroma cacao seed butter

Theobroma cacao extract~0.3–0.55%

Comedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

More about Theobroma cacao extract

Carbomer~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Tocopheryl acetate~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Tocopherol~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Retinyl palmitate~0.25–0.45%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate

Ascorbic acid~0.25–0.5%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-oxidationAnti-aging

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Tetrasodium edta~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Helps to stabilize the product formulation

More about Tetrasodium edta

Triethanolamine~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine

Bht~0.25–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Bht

Polysorbate 20~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Dmdm hydantoin~0.25–0.5%

Irritant · high

Irritation risk: High

A preservative that releases formaldehyde and can be irritating

More about Dmdm hydantoin

Phenoxyethanol~0.3–0.55%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Caprylyl glycol~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Propylene glycol~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol

Palmitoyl oligopeptide~0.4–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

CleansingMoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide

Palmitoyl tetrapeptide-7~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Sorbic acid~0.25–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about Sorbic acid

Punica granatum extract~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationEvens skin tone

A plant extract that can help neutralize free radicals in skin and even out the skin tone, but is typically used in products in a concentration that is too low to be effective

More about Punica granatum extract

Vitis vinifera seed extract~0.3–0.5%

Key active

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract

Pinus strobus bark extract~0.25–0.5%

Formula

Irritation risk: Low

More about Pinus strobus bark extract

Camellia sinensis leaf extract~0.25–0.5%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Ginseng

Not recognized

Panax ginseng extract~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that might have anti-oxidant properties. Can be irritating

More about Panax ginseng extract

Chamomilla recutita flower extract~0.2–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract

Algae extract~0.25–0.45%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-aging

Plant extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but research is not extensive yet

More about Algae extract

Arctostaphylos uva-ursi leaf extract~0.15–0.3%

Formula

Irritation risk: Low

More about Arctostaphylos uva-ursi leaf extract

Rosa damascena flower~0.15–0.3%

Irritant · high

Irritation risk: High

More about Rosa damascena flower

Echinacea angustifolia extract~0.1–0.15%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Plant extract that might contain antioxidants, have antibacterial effect and help reduce inflammation, but solid evidence is lacking. Can be irritating

More about Echinacea angustifolia extract

Glycyrrhiza glabra root extract~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Reduces rednessEvens skin toneAnti-oxidationAnti-inflammatoryAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract

Ingredient list view

Water, C12-15 alkyl benzoate, Prunus amygdalus dulcis oil, Prunus amygdalus dulcis seed, Glycerin, Dimethicone, Sorbitan stearate, Glyceryl stearate, Peg-100 stearate, Cetearyl alcohol, Ceteareth-20, Butyrospermum parkii butter, Stearic acid, Butylene glycol, Acetyl hexapeptide-8, Sodium hyaluronate, Panthenol, Theobroma cacao seed butter, Theobroma cacao extract, Carbomer, Tocopheryl acetate, Tocopherol, Retinyl palmitate, Ascorbic acid, Tetrasodium edta, Triethanolamine, Bht, Polysorbate 20, Dmdm hydantoin, Phenoxyethanol, Caprylyl glycol, Propylene glycol, Palmitoyl oligopeptide, Palmitoyl tetrapeptide-7, Sorbic acid, Punica granatum extract, Vitis vinifera seed extract, Pinus strobus bark extract, Camellia sinensis leaf extract, Unknown, Panax ginseng extract, Chamomilla recutita flower extract, Algae extract, Arctostaphylos uva-ursi leaf extract, Rosa damascena flower, Echinacea angustifolia extract, Glycyrrhiza glabra root extract

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Hydroxatone®AM/PM Anti-wrinkleYOUR PRODUCT	Peter Thomas RothMega-Rich Intensive Anti-Aging Cellular Creme	M-61Major Moisture!	BradceuticalsCLASSIC MESENCHYMAL STEM CELL SERUM
Match	—	56%	53%	51%
Price	—	$85.00	—	$69.99
Shared key ingredients	—	7 of 16	6 of 16	6 of 16
Key difference	—	Retinol	Acetyl Tetrapeptide-11	Hydroxyethyl Urea
Irritancy	High	High	Medium	Medium
Drying alcohol	—	Contains drying alcohol	—	—
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Product summary

"Hydroxatone® - AM/PM Anti-wrinkle" is effective for: Moisturizing

This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (0.25% - 0.50%) it cannot have a noticeable benefit for the skin.
This product includes a form of Retinoids (vitamin A) - retinyl palmitate 0.25% - 0.45%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
Peptides (palmitoyl tetrapeptide-7 0.30% - 0.55%, palmitoyl oligopeptide 0.40% - 0.60% and acetyl hexapeptide-8 0.40% - 0.65%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Humectants (algae extract 0.25% - 0.45%, panthenol 0.40% - 0.65%, sodium hyaluronate 0.45% - 0.65%, acetyl hexapeptide-8 0.40% - 0.65% and glycerin 2.40% - 3.00%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.