Perricone MD Treatments Neuropeptide Night Cream

Based on the ingredients included, "Perricone MD - Treatments Neuropeptide Night Cream" works well for moisturizing the skin. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, urea, fructose, glycerin and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide 2, palmitoyl tetrapeptide-7, butyrospermum parkii butter, dimethicone and squalane) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

• Another benefit is that this moisturizer contain ceramides (ceramide 2 0.25% - 0.45%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
• This moistruizer also contains peptides (palmitoyl oligopeptide 0.20% - 0.35%, palmitoyl tetrapeptide-7 0.15% - 0.25%, dipeptide-2 0.15% - 0.25%, tetrapeptide-21 0.15% - 0.30%, pentapeptide-18 0.20% - 0.35% and acetyl hexapeptide-8 0.20% - 0.35%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.