Works for:
based on ingredients and %- Moisturizing
- Anti-aging
Doesn't work for:
based on ingredients and %- Evens skin tone
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 2
Key actives
Product Summary
Based on the ingredients included, "Perricone MD - Treatments Neuropeptide Night Cream" works well for moisturizing the skin. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (acetyl hexapeptide-8, urea, fructose, glycerin and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide 2, palmitoyl tetrapeptide-7, butyrospermum parkii butter, dimethicone and squalane) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- Another benefit is that this moisturizer contain ceramides (ceramide 2 0.25% - 0.45%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
- This moistruizer also contains peptides (palmitoyl oligopeptide 0.20% - 0.35%, palmitoyl tetrapeptide-7 0.15% - 0.25%, dipeptide-2 0.15% - 0.25%, tetrapeptide-21 0.15% - 0.30%, pentapeptide-18 0.20% - 0.35% and acetyl hexapeptide-8 0.20% - 0.35%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
About the brand
According to Cruelty-Free Kitty "Perricone MD" is cruelty free and so is its parent company.
Moisturizing
What does the product description say?
Hydrating, nourishing and soothing.
Source: Allbeauty
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
fructose, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide 2, dipeptide-2, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, pentapeptide-18, tetrapeptide-21, urea
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A sugar that attracts water to the upper layer of the skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Helps attract water to the upper layer of the skin
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
Naturally present in skin and helps to attract water to its upper layer
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
Helps soften the skin and attract water to its upper layer. Helps create nice product texture
Used to create a thicker product consistency and soften the upper layer of the skin
Used to create a nice product consistency while softening the upper layer of the skin
Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness
Helps preserve products and creates a nice product texture
Used to preserve products, dissolve other ingredients and create a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Anti-aging
What does the product description say?
Benefits. . Minimises the appearance of fine line and wrinkles. . Develops radiant, younger and brighter looking skin. .
Source: Allbeauty
This product contains acetyl hexapeptide-8, dipeptide-2, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, pentapeptide-18, tetrapeptide-21. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Evens skin tone
What does the product description say?
This unique complex is released upon contact with the skin to maximise hydration, minimise the appearance of lines, uneven skin tone, and to increase radiance and glow.
Source: Allbeauty
Effective ingredients missing or their concentration is too low
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Anti-aging | |
| Evens skin tone |
Total Promises Fulfilled score: 58/100.
Potential irritants
Comedogenic ingredients
User reviews (0)
Averages from community submissions.
No reviews yet for this product.
Be the first to share your experience!
Tried this product?
Help capture what the ingredient list can't—texture, finish, pilling, scent, and more. Answer what you can, skip the rest.
Takes ~30 seconds.
Reviews are shown in aggregate. No personal details.
Key Actives
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Helps attract water to the upper layer of the skin
A sugar that attracts water to the upper layer of the skin
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
Naturally present in skin and helps to attract water to its upper layer
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Potential irritants
An aromatic blend of unspecified and possibly irritating ingredients
Used as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating
Might help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
Can work as an exfoliant but is typically used to adjust the product pH
Helps preserve products and creates a nice product texture
Used to preserve products, dissolve other ingredients and create a nice product texture
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
Comedogenic ingredients
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness
Used to create a nice product consistency while softening the upper layer of the skin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin
Helps soften the skin and attract water to its upper layer. Helps create nice product texture
A gelling agent that thickens the product consistency and leaves the skin with a velvety finish
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Is used to enhance product texture and can help to optically mask skin imperfections
Can work as an exfoliant but is typically used to adjust the product pH
A preservative. It helps prevent bacterial growth in cosmetic products
An aromatic blend of unspecified and possibly irritating ingredients
Helps preserve products and creates a nice product texture
Used to create a thicker product consistency and soften the upper layer of the skin
Used as a cleansing agent (surfactant) in cleansers. Helps water and oil mix together in lotions. Can be irritating
Used to preserve products, dissolve other ingredients and create a nice product texture
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Might help neutralize free radicals in skin. Is claimed to be able to improve the appearance of undereye darkness but evidence is missing. Can be an allergen and cause irritation
A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product
Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures
Naturally present in skin and helps to attract water to its upper layer
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps attract water to the upper layer of the skin. Could be helpful in restoring the skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Ingredient list view
Water, Glycerin, Isononyl isononanoate, Pentaerythrityl tetraethylhexanoate, Cetearyl alcohol, Butyrospermum parkii butter, C12-20 acid peg-8 ester, Dimethyl isosorbide, C10-18 triglycerides, Isodecyl salicylate, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Butylene glycol, Squalane, C12-15 alkyl benzoate, Dimethicone, Polymethyl methacrylate, Dimethyl mea, Citric acid, Phenoxyethanol, Parfum, Caprylyl glycol, Tribehenin, Coco-glucoside, Polysorbate 60, Tyrosine, Pentylene glycol, Potassium sorbate, Tocopheryl acetate, Dipotassium glycyrrhizate, Hesperidin methyl chalcone, Hexylene glycol, Ceramide 2, Sodium hydroxide, Urea, Fructose, Peg-10 rapeseed sterol, Disodium edta, Steareth-20, Allantoin, Trehalose, Sodium lactate, Sodium chloride, Sodium pca, Maltose, Acetyl hexapeptide-8, Pentapeptide-18, Tetrapeptide-21, Glucose, Sodium hyaluronate, Dipeptide-2, Palmitoyl tetrapeptide-7, Palmitoyl oligopeptide
- Glycerol and the skin: holistic approach to its origin and functions
- Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics
- Activity enhancement of ferulic acid with dimethyl isosorbride in cosmetic compositions
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- In Vitro Assessment of Skin Irritation Potential of Surfactant-based Formulations by Using a 3-D Skin Reconstructed Tissue Model and Cytokine Response
- Allergen of the Year—Alkyl Glucoside
- Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model
- Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.
- Hesperidin methyl chalcone - a new cosmetic contact allergen
- Benefits of Hesperidin for Cutaneous Functions
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Topical urea in skincare: A review
- Profile of wound healing process induced by allantoin
- Topical Glucose Induces Claudin-1 and Filaggrin Expression in a Mouse Model of Atopic Dermatitis and in Keratinocyte Culture, Exerting Anti-inflammatory Effects by Repairing Skin Barrier Function
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care