Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
- Anti-oxidation
Can it cause trouble?
- Irritation risk: low
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"DefenAge Pro - 8-in-1 BioSerum" is effective for: Anti-aging, Moisturizing, Evens skin tone and Anti-blemish
Ingredient callouts
- A good concentration of Niacinamide (3.10% - 3.80%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Peptides (palmitoyl tripeptide-38 0.55% - 0.80%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Humectants (sodium hyaluronate 0.50% - 0.75% and glycerin 4.20% - 5.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Anti-aging
What does the product description say?
Improves the overall health and appearance of the skin Rejuvenates smoothness and improves overall visible skin health and quality Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations Promotes radiance and revives the skin’s natural moisture for an ultimate glow
Source: N/A
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: arabidopsis thaliana extract, palmitoyl tripeptide-38.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Anti-oxidation
This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
Might help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin
Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Evens skin tone
What does the product description say?
Improves the overall health and appearance of the skin Rejuvenates smoothness and improves overall visible skin health and quality Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations Promotes radiance and revives the skin’s natural moisture for an ultimate glow
Source: N/A
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Moisturizing
What does the product description say?
Improves the overall health and appearance of the skin Rejuvenates smoothness and improves overall visible skin health and quality Minimizes the look of fine lines, wrinkles, pores, and skin pigmentation and discolorations Promotes radiance and revives the skin’s natural moisture for an ultimate glow
Source: N/A
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cyclopentasiloxane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, palmitoyl tripeptide-38
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A type of silicone that helps to soften upper layer of the skin and create a nice product texture
Helps preserve products and creates a nice product texture
Used to stabilize product formulations and help soften the upper layer of the skin
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 DefenAge Pro 8-in-1 BioSerum | Current | $264.00 | |
DefenAge Skincare Products DefenAge 8-in-1 Bioserum | 87% | - | |
Spectacle Skincare Performance Crème | 75% | $76.00 | |
 QMS Medicosmetics Advanced Collagen Serum in Oil | 72% | $205.00 | |
 Optimum Superdrug Optimum Collagen Serum | 72% | $7.49 | |
up & up PM Facial Moisturizing Lotion - - up & up™ | 72% | - |
Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Potential irritants
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used to stabilize product formulations and help soften the upper layer of the skin
An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics
Helps preserve products and creates a nice product texture
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
Used to stabilize product formulations and create a nice product texture
A type of silicone that helps to soften upper layer of the skin and create a nice product texture
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking
Might help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin
Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen
A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
Used to create a thicker product consistency and stabilize formulations
Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin
Used to stabilize product formulations and help soften the upper layer of the skin
An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics
A preservative. It helps prevent bacterial growth in cosmetic products
Helps preserve products and creates a nice product texture
Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures
Ingredient list view
Water, Cyclopentasiloxane, Glycerin, Niacinamide, Sinorhizobium meliloti ferment filtrate, Dimethicone, Polysorbate 20, Dimethicone/vinyl dimethicone crosspolymer, Lauryl peg-9 polydimethylsiloxyethyl dimethicone, Ammonium acryloyldimethyltaurate/vp copolymer, Phospholipids, Unknown, Palmitoyl tripeptide-38, Sodium hyaluronate, Arabidopsis thaliana extract, Sea whip extract, Ergothioneine, Tocopheryl acetate, Ubiquinone, Leuconostoc/radish root ferment filtrate, Unknown, Glutamine, Caprylic/capric triglyceride, Cetyl hydroxyethylcellulose, Lecithin, Hydroxypropyl cyclodextrin, Phytic acid, Phenoxyethanol, Caprylyl glycol, Ethylhexylglycerin, Hexylene glycol, Sodium chloride
- Glycerol and the skin: holistic approach to its origin and functions
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Repair of Damaged DNA by Arabidopsis Cell Extract
- Marine ingredients and the skin
- A comparison of the relative antioxidant potency of L‐ergothioneine and idebenone
- l-Ergothioneine Protects Skin Cells against UV-Induced Damage—A Preliminary Study
- Cosmetic and dermatologic use of alpha hydroxy acids
- Comparative Evaluation of Efficacy and Tolerability of Glycolic Acid, Salicylic Mandelic Acid, and Phytic Acid Combination Peels in Melasma