DefenAge Skincare Products DefenAge 8-in-1 Bioserum

Can it work? Irritants Ingredient list Sources Similar products Q&A Price comparison

WORKS FOR

Anti-aging
Anti-oxidation
Moisturizing
Evens skin tone
Anti-blemish
+1 more

KEY INGREDIENTS

niacinamide
palmitoyl tripeptide-38
caprylic/capric triglyceride
cyclopentasiloxane
dimethicone
ergothioneine
glycerin
Sunflower seed oil
sea whip extract
sodium hyaluronate
alanyl glutamine
ubiquinone
arabidopsis thaliana extract
+9 more

IRRITANCY

MEDIUM

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https://www.skinelite.com

$148.50

In stock

Size: 1.5 oz

DefenAge 8-in-1 Bioserum

Can the product deliver on its promises?

See a mistake?

Promise

What does the product description say?

"Designed to activate, orchestrate and energize, this biologically-advanced anti aging cream-like serum concentrate provides an unprecedented concentration of defensin molecules contained in the Age-Repair Defensin ® Complex."

N/A

WIMJ summary for anti-aging

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: alanyl glutamine, arabidopsis thaliana extract, palmitoyl tripeptide-38.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Ingredient	Effectiveness	Concentration	Irritancy
niacinamide	HIGH
alanyl glutamine	MEDIUM
arabidopsis thaliana extract	MEDIUM

See a mistake?

WIMJ summary for anti-blemish

This product might be able to help reduce blemishes and clogged pores because it contains niacinamide.

Ingredient	Effectiveness	Concentration	Irritancy
niacinamide	HIGH
rosmarinus officinalis leaf extract	LOW

See a mistake?

WIMJ summary for evens skin tone

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Ingredient	Effectiveness	Concentration	Irritancy
niacinamide	HIGH

See a mistake?

WIMJ summary for moisturizing

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanyl glutamine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, palmitoyl tripeptide-38

Ingredient	Effectiveness	Concentration	Irritancy
alanyl glutamine	HIGH
glycerin	HIGH
helianthus annuus seed oil	HIGH

See a mistake?

WIMJ summary for anti-oxidation

This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Ingredient	Effectiveness	Concentration	Irritancy
ubiquinone	HIGH
sea whip extract	LOW
ergothioneine	HIGH

How honest is this product?

Promise	Can it deliver?
Anti-aging

Total Promises Fulfilled score: 100/100.

Potential irritants

IRRITANCY

MEDIUM

Ingredient	Irritancy	Skin Benefit
arabidopsis thaliana extract
rosmarinus officinalis leaf extract
tocopheryl acetate

Ingredients by volume

Ingredient	Estimated concentration
water Plain old water	45% - 55%
cyclopentasiloxane A silicone that helps improve the product texture and spreadability. Can absord oil creating a short-term mattifying effect on the skin	6.9% - 8.5%
glycerin One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant	4.2% - 5.1%
niacinamide Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture	3.1% - 3.8%
sinorhizobium meliloti ferment filtrate	2.3% - 2.8%
dimethicone A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish	2.1% - 2.5%
polysorbate 20 Helps oil and water mix together	1.7% - 2%
dimethicone/vinyl dimethicone crosspolymer Used to stabilize product formulations and create a nice product texture	1.4% - 1.7%
lauryl peg-9 polydimethylsiloxyethyl dimethicone A type of silicone that helps to soften upper layer of the skin and create a nice product texture	1.1% - 1.4%
ammonium acryloyldimethyltaurate/vp copolymer Increases thickness of a product. Texture enhancer for oil-in-water emulsions	0.9% - 1.1%
phospholipids Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product	0.65% - 1%
unknown The ingredient is not recognized	TBC
palmitoyl tripeptide-38 A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles	0.55% - 0.8%
sodium hyaluronate One of the best moisturizing ingredients. Attracts water into the upper layer of the skin	0.5% - 0.75%
arabidopsis thaliana extract Plant extract that might be helpful in repairing sun damage but evidence of effectiveness in skin are lacking	0.45% - 0.65%
sea whip extract Might help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin	0.4% - 0.6%
ergothioneine Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking	0.4% - 0.6%
helianthus annuus seed oil A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function	0.45% - 0.65%
rosmarinus officinalis leaf extract Can be helpful in reducing inflammation in skin. Is a likely irritant	0.3% - 0.55%
tocopheryl acetate A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.	0.3% - 0.55%
ubiquinone Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen	0.3% - 0.55%
leuconostoc/radish root ferment filtrate A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine	0.25% - 0.45%
albumen	0.25% - 0.45%
alanyl glutamine A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles	0.2% - 0.4%
caprylic/capric triglyceride A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin	0.25% - 0.5%
cetyl hydroxyethylcellulose Used to create a thicker product consistency and stabilize formulations	0.2% - 0.4%
lecithin Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin	0.25% - 0.45%
hydroxypropyl cyclodextrin Used to stabilize product formulations and help soften the upper layer of the skin	0.2% - 0.4%
phytic acid An alpha-hydroxy acid (AHA), but is mostly used to stabilize product formulations in cosmetics	0.15% - 0.3%
phenoxyethanol A preservative. It helps prevent bacterial growth in cosmetic products	0.1% - 0.25%
caprylyl glycol Helps preserve products and creates a nice product texture	0.15% - 0.3%
ethylhexylglycerin A preservative	0.1% - 0.15%
hexylene glycol Helps create a more spreadable product texture	0.05% - 0.1%
sea salt Used to thicken the product formulation and might help to add minerals to the surface of the skin. It is used in scrubs as a physical exfoliant. Can increase sensitivity to other ingredients if left on the skin or used in high concentration	0.05% - 0.1%
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Similar products & dupes

	DefenAge Skincare Products - DefenAge 8-in-1 Bioserum
Price
WIMJ similarity score
Key ingredients	niacinamide palmitoyl tripeptide-38 +11 more
Irritancy	IRRITANCY MEDIUM
Potential Irritants	rosmarinus officinalis leaf extract Has skin benefit? sea salt Has skin benefit? hexylene glycol Has skin benefit? ethylhexylglycerin Has skin benefit? caprylyl glycol Has skin benefit? phytic acid Has skin benefit? hydroxypropyl cyclodextrin Has skin benefit? caprylic/capric triglyceride Has skin benefit? leuconostoc/radish root ferment filtrate Has skin benefit? tocopheryl acetate Has skin benefit? arabidopsis thaliana extract Has skin benefit? +9 more
All ingredients	water Has skin benefit? cyclopentasiloxane Has skin benefit? +32 more