Clark's Botanicals

Clark's Botanicals Retinol Rescue Overnight Cream

Name: Clark's Botanicals - Retinol Rescue Overnight Cream
Brand: Clark's Botanicals

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Evens skin tone

Retinol, Glucosamine hcl + 4 more

Works well

What the product description says

“A trio of time-released retinol, high-potency retinol and micro-encapsulated vitamin C work together to help brighten the appearance of skin, reduce the appearance of fine lines and reveal a fresher, more youthful-looking complexion.”

Source: SpaceNK US

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glucosamine hcl.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.6%

Glucosamine hclKey activeEffect: MediumMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.3–0.55%

Hydrolyzed yeast extractEffect: LowHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~0.3–0.55%

Yeast extractEffect: Low, below effective doseHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.3–0.55%

NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.35–0.65%

Ascorbyl tetraisopalmitateUnder-dosedA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.35–0.65%

Anti-aging

Retinol, Palmitoyl tripeptide-5 + 6 more

Works well

What the product description says

“A trio of time-released retinol, high-potency retinol and micro-encapsulated vitamin C work together to help brighten the appearance of skin, reduce the appearance of fine lines and reveal a fresher, more youthful-looking complexion.”

Source: SpaceNK US

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.7%

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.3–0.55%

Glucosamine hclEffect: LowMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.3–0.55%

Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.3–0.55%

Moisturizing

Isosorbide dicaprylate, Palmitoyl tripeptide-5 + 24 more

Works well

What the product description says

“Other key ingredients include colloidal oatmeal, red clover flower extract, jasmine and vitamin E, all chosen for their soothing and protecting properties to help calm and moisturise the skin.”

Source: SpaceNK US

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: avena sativa kernel flour, glucosamine hcl.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, simmondsia chinensis seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: isosorbide dicaprylate, palmitoyl tripeptide-5, panthenol

Isosorbide dicaprylateHero· EmollientEffect: HighHelps soften the upper layer of the skin. Early studies suggest that it can help strengthen the skin barrier~2.4–2.9%

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.7%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.3–0.55%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.8–4.7%

Diheptyl succinateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin and creates a nice product finish on the skin~3.1–3.8%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%

Capryloyl glycerin/sebacic acid copolymerKey activeEffect: MediumHelps soften the upper layer of the skin~1.7–2.1%

Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~1.3–1.6%

Synthetic beeswaxKey activeEffect: HighHelps soften the upper layer of the skin~1–1.2%

Avena sativa kernel flourKey active· Humectant, EmollientEffect: HighA type of colloidal oatmeal. Can contain potent antioxidants and anti-inflammatory compounds. Is effective in supporting skin barrier~0.4–0.65%

Hypnea musciformis extractKey active· HumectantEffect: MediumMight help to attract water to the upper layer of the skin~0.4–0.65%

TricaprylinKey active· EmollientEffect: MediumAn emollient that helps soften the skin. Can increase penetration of other ingredients~0.35–0.6%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.3–0.55%

Glucosamine hclKey active· HumectantEffect: HighMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.3–0.55%

Hydrolyzed yeast extractKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~0.3–0.55%

Glucosyl hesperidinKey active· HumectantEffect: MediumMight be able to neutralize free radicals in skin. Also works as a humectant~0.3–0.55%

Plankton extractKey activeEffect: MediumCan help attract water to the upper layer of the skin~0.3–0.55%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.5–1.8%

Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.7–1%

Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~0.65–1%

Glyceryl caprylate· EmollientEffect: LowAn emollient that can also help water and oil mix together, as well as prevent bacteria growth in products~0.4–0.6%

Ascorbyl tetraisopalmitateEffect: Low, below effective doseA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)~0.35–0.65%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.35–0.65%

Yeast extractUnder-dosedHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.3–0.55%

Laminaria digitata extractUnder-dosedSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.3–0.55%

Anti-oxidation

Side benefit · Retinol, Butyrospermum parkii butter + 8 more

Works well

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.6%

Trifolium pratense flower extractEffect: LowRed clover flower extract. Can contain anti-oxidants but also potential irritant compounds~0.3–0.55%

Glucosyl hesperidinEffect: LowMight be able to neutralize free radicals in skin. Also works as a humectant~0.3–0.55%

Glucosamine hclEffect: LowMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.3–0.55%

Hydrolyzed yeast extractEffect: LowHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~0.3–0.55%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.3–0.6%

Yeast extractUnder-dosedHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.3–0.55%

Exfoliation

Side benefit · Retinol

Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

Anti-blemish

Side benefit the brand mentions · Retinol, Niacinamide

Works well

What the product description says

“Face the day ahead with Clarks Retinol Rescue Overnight Cream.”

Source: SpaceNK

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

Can it cause trouble?

Irritancy

9 strong irritants: Jasminum officinale flower extract, Arnica montana flower extract + 7 more — patch-test recommended

High risk

We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Jasminum officinale flower extractFragrance. Can be irritatingHigh~0.45–0.7%est.

Arnica montana flower extractA plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skinHigh~0.4–0.6%est.

RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.3–0.6%est.

Trifolium pratense flower extractRed clover flower extract. Can contain anti-oxidants but also potential irritant compoundsHigh~0.3–0.55%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.25%est.

Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.1–0.15%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.15–0.25%est.

GeraniolA fragrance. Can be irritatingHigh~0.1–0.25%est.

Amyl cinnamal—High~0.1–0.15%est.

LinaloolA fragrance. Can be irritatingHigh~0.1–0.15%est.

Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~1.3–1.6%est.

Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.6–0.9%est.

C8-22 alkyl acrylates/methacrylic acid crosspolymer—Medium~0.5–0.8%est.

Ascorbyl tetraisopalmitateA vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)Medium~0.35–0.65%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.6%est.

Plankton extractCan help attract water to the upper layer of the skinMedium~0.3–0.55%est.

Caprylhydroxamic acidA preservativeMedium~0.3–0.55%est.

Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.3–0.55%est.

Potassium sorbateA preservativeMedium~0.15–0.3%est.

Comedogenic

4 ingredients rated 2 or more on the 0–5 pore-clogging scale

4 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2–2.4%est.

Hypnea musciformis extractMight help to attract water to the upper layer of the skin3/5~0.4–0.65%est.

Plankton extractCan help attract water to the upper layer of the skin3/5~0.3–0.55%est.

Laminaria digitata extractSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment3/5~0.3–0.55%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Ppg-3 benzyl ether myristate~5.3–6.4%

Formula

Irritation risk: Low

More about Ppg-3 benzyl ether myristate

Glycerin~3.8–4.7%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Diheptyl succinate~3.1–3.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and creates a nice product finish on the skin

More about Diheptyl succinate

Isosorbide dicaprylate~2.4–2.9%

Hero · Moisturizing

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin. Early studies suggest that it can help strengthen the skin barrier

More about Isosorbide dicaprylate

Butyrospermum parkii butter~2–2.4%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Capryloyl glycerin/sebacic acid copolymer~1.7–2.1%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Capryloyl glycerin/sebacic acid copolymer

Glyceryl stearate~1.5–1.8%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Simmondsia chinensis seed oil~1.3–1.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil

Synthetic beeswax~1–1.2%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Synthetic beeswax

Propanediol~0.75–1.1%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Behenyl alcohol~0.7–1%

Formula

Irritation risk: Low

Works for

Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol

Potassium cetyl phosphate~0.6–0.9%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate

Stearic acid~0.65–1%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

C8-22 alkyl acrylates/methacrylic acid crosspolymer~0.5–0.8%

Irritant · medium

Irritation risk: Medium

More about C8-22 alkyl acrylates/methacrylic acid crosspolymer

Palmitoyl tripeptide-5~0.5–0.7%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Jasminum officinale flower extract~0.45–0.7%

Irritant · high

Irritation risk: High

Fragrance. Can be irritating

More about Jasminum officinale flower extract

Arnica montana flower extract~0.4–0.6%

Irritant · high

Irritation risk: High

A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin

More about Arnica montana flower extract

Hypnea musciformis extract~0.4–0.65%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

Might help to attract water to the upper layer of the skin

More about Hypnea musciformis extract

Niacinamide~0.35–0.65%

Under-dosed

Irritation risk: Low

Works for

Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Retinol~0.3–0.6%

Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high

Irritation risk: High

Works for

Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol

Ascorbyl tetraisopalmitate~0.35–0.65%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationEvens skin toneAnti-agingMoisturizing

A vitamin C derivative. Studies show that is might be effective in reducing hyperpigmentation, but there are no studies confirming that it is effectively converted into the bioavailable form of Vitamin C in skin. It is not clear how this derivative compares in effectiveness to the topical application of bioavailable form of vitamin C (L-ascorbic acid)

More about Ascorbyl tetraisopalmitate

Avena sativa kernel flour~0.4–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of colloidal oatmeal. Can contain potent antioxidants and anti-inflammatory compounds. Is effective in supporting skin barrier

More about Avena sativa kernel flour

Trifolium pratense flower extract~0.3–0.55%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Red clover flower extract. Can contain anti-oxidants but also potential irritant compounds

More about Trifolium pratense flower extract

Glucosyl hesperidin~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Might be able to neutralize free radicals in skin. Also works as a humectant

More about Glucosyl hesperidin

Panthenol~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Tocopheryl acetate~0.3–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Hyaluronic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Ribose~0.3–0.55%

Formula

Irritation risk: Low

More about Ribose

Plankton extract~0.3–0.55%

Key activeComedogenic 3/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 3/5

Works for

Moisturizing

Can help attract water to the upper layer of the skin

More about Plankton extract

Hydrolyzed yeast extract~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingEvens skin toneAnti-oxidation

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties

More about Hydrolyzed yeast extract

Glucosamine hcl~0.3–0.55%

Key active

Irritation risk: Low

Works for

AntibacterialMoisturizingEvens skin toneAnti-oxidationAnti-aging

Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.

More about Glucosamine hcl

Yeast extract~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-oxidationReduces irritationEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

More about Yeast extract

Lecithin~0.35–0.65%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Laminaria digitata extract~0.3–0.55%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

Seaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment

More about Laminaria digitata extract

Isopentyldiol~0.3–0.55%

Formula

Irritation risk: Low

Helps dissolve other ingredients in a formulation

More about Isopentyldiol

Caprylhydroxamic acid~0.3–0.55%

Irritant · medium

Irritation risk: Medium

A preservative

More about Caprylhydroxamic acid

Glyceryl caprylate~0.4–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate

Leuconostoc/radish root ferment filtrate~0.3–0.55%

Irritant · medium

Irritation risk: Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate

Cellulose acetate butyrate~0.3–0.6%

Formula

Irritation risk: Low

More about Cellulose acetate butyrate

Tricaprylin~0.35–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin. Can increase penetration of other ingredients

More about Tricaprylin

Xanthan gum~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Carbomer~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Cetyl hydroxyethylcellulose~0.3–0.55%

Formula

Irritation risk: Low

Used to create a thicker product consistency and stabilize formulations

More about Cetyl hydroxyethylcellulose

Aminomethyl propanol~0.3–0.5%

Formula

Irritation risk: Low

Used to adjust the pH in formulations

More about Aminomethyl propanol

Polyglucuronic acid~0.3–0.5%

Formula

Irritation risk: Low

Often used to support the moisturization effect of polysaccharides (contained, for example, in yeast extract)

More about Polyglucuronic acid

Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.3–0.55%

Formula

Irritation risk: Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate

Polymethyl methacrylate~0.25–0.5%

Formula

Irritation risk: Low

Is used to enhance product texture and can help to optically mask skin imperfections

More about Polymethyl methacrylate

Sodium phytate~0.25–0.45%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Sodium benzoate~0.2–0.35%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Potassium sorbate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Parfum~0.15–0.25%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Benzyl alcohol~0.1–0.15%

Irritant · high

Irritation risk: High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol

Limonene~0.15–0.25%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Geraniol~0.1–0.25%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Geraniol

Amyl cinnamal~0.1–0.15%

Irritant · high

Irritation risk: High

More about Amyl cinnamal

Linalool~0.1–0.15%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Ingredient list view

Water, Ppg-3 benzyl ether myristate, Glycerin, Diheptyl succinate, Isosorbide dicaprylate, Butyrospermum parkii butter, Capryloyl glycerin/sebacic acid copolymer, Glyceryl stearate, Simmondsia chinensis seed oil, Synthetic beeswax, Propanediol, Behenyl alcohol, Potassium cetyl phosphate, Stearic acid, C8-22 alkyl acrylates/methacrylic acid crosspolymer, Palmitoyl tripeptide-5, Jasminum officinale flower extract, Arnica montana flower extract, Hypnea musciformis extract, Niacinamide, Retinol, Ascorbyl tetraisopalmitate, Avena sativa kernel flour, Trifolium pratense flower extract, Glucosyl hesperidin, Panthenol, Tocopheryl acetate, Hyaluronic acid, Ribose, Plankton extract, Hydrolyzed yeast extract, Glucosamine hcl, Yeast extract, Lecithin, Laminaria digitata extract, Isopentyldiol, Caprylhydroxamic acid, Glyceryl caprylate, Leuconostoc/radish root ferment filtrate, Cellulose acetate butyrate, Tricaprylin, Xanthan gum, Carbomer, Cetyl hydroxyethylcellulose, Aminomethyl propanol, Polyglucuronic acid, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Polymethyl methacrylate, Sodium phytate, Sodium benzoate, Potassium sorbate, Parfum, Benzyl alcohol, Limonene, Geraniol, Amyl cinnamal, Linalool

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$136.50 Out of stock

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$150.00

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	Clark's BotanicalsRetinol Rescue Overnight CreamYOUR PRODUCT	AHCEye Cream For Face	innisfreeRetinol Cica Barrier Defense Cream	DermalogicaMultiVitamin Power Recovery Cream Crème Hydratante
Match	—	78%	77%	73%
Price	$150.00	$14.75−$135.25	$4.88−$145.12	$109.00−$41.00
Shared key ingredients	—	6 of 14	4 of 14	5 of 14
Key difference	—	Copper Tripeptide-1	Madecassoside	Aminopropyl Ascorbyl Phosphate
Irritancy	High	High	Medium	High
Drying alcohol	—	Contains drying alcohol	—	—
	View product	Shop	Shop	Shop

More alternatives: Goodal Black Carrot Vita-A Retinol Cream Frankly Retinol 0.1% Wrinkle Care Cream

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Product summary

"Clark's Botanicals - Retinol Rescue Overnight Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (panthenol, glucosamine hcl, glycerin, hyaluronic acid and hydrolyzed yeast extract) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (isosorbide dicaprylate, beeswax, butyrospermum parkii butter, simmondsia chinensis seed oil and diheptyl succinate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

this moisturizer contains an effective form of retinoids (vitamin A): retinol 0.30% - 0.60%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
This moistruizer also contains peptides (palmitoyl tripeptide-5 0.50% - 0.70%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 115.00$ up to 136.50$ in the United States, for 132.30CA$ in Canada and from 105.00£ up to 152.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 25 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Improvement of hydration and epidermal barrier function in human skin by a novel compound isosorbide dicaprylatepubmed.ncbi.nlm.nih.gov
3
Effects of Topical Arnica Gel on Post-Laser Treatment Bruisesonlinelibrary.wiley.com
4
Effects of microcurrent application alone or in combination with topical Hypericum perforatum L. and Arnica montana L. on surgically induced wound healing in Wistar ratsthieme-connect.com
5
The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.)onlinelibrary.wiley.com
6
Accelerated resolution of laser‐induced bruising with topical 20% arnica: a rater‐blinded randomized controlled trialonlinelibrary.wiley.com
7
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
8
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
9
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
10
Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
11
A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
12
Assessment of penetration of Ascorbyl Tetraisopalmitate into biological membranes by molecular dynamicssciencedirect.com
13
Stability evaluation of tocopheryl acetate and ascorbyl tetraisopalmitate in isolation and incorporated in cosmetic formulations using thermal analysisscielo.br
14
A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative propertiessciencedirect.com
15
New lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), suppresses senile lentigo through controlling of melanocytes-keratinocytes interactionmorressier.com
16
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
17
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
18
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
19
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
20
The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transferncbi.nlm.nih.gov
21
Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitaminsresearchgate.net
22
Glucosamine: an ingredient with skin and other benefitsncbi.nlm.nih.gov
23
Polyglucuronic acids: Structures, functions and degrading enzymessciencedirect.com
24
Safety Assessment of Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate as Used in Cosmeticscir-safety.org
25
Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extractsec.europa.eu

Clark's BotanicalsRetinol Rescue Overnight Cream

Buy on Amazon$150.00 · as of 11/13 12:31 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$150.00 · as of 11/13 12:31 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.