Swiss Clinic

Swiss Clinic Day Cream

Name: Swiss Clinic - Day Cream
Brand: Swiss Clinic

Efficacy100/100IrritancyHigh

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Works for

2 of 2 advertised claims delivered

Anti-aging

Gluconolactone, Acetyl decapeptide-3 + 9 more

Strong evidence

What the product description says

“The face cream is designed to revitalise the complexion and reduce the appearance of fine lines with a firming and lifting effect.”

Source: Lookfantastic

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains gluconolactone.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl decapeptide-3, adenosine phosphate, palmitoyl tripeptide-5, sh-oligopeptide-1, sh-polypeptide-2.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.65–1%

Acetyl decapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Adenosine phosphateKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to stimulate collagen production in skin~0.2–0.4%

Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

Sh-polypeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.4%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Lactic acidUnder-dosedEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.4%

Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.15–0.25%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%

Moisturizing

Sh-oligopeptide-1, Acetyl decapeptide-3 + 30 more

Strong evidence

What the product description says

“Pamper your skin with the luxuriously hydrating Swiss Clinic Day Cream .”

Source: Lookfantastic

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl decapeptide-3, palmitoyl tripeptide-5, sh-oligopeptide-1

Saccharum officinarum extractKey activeEffect: HighSugar extract that helps attract water to the upper layer of the skin~0.15–0.25%

Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Sh-polypeptide-2Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.25%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.25–0.45%

Acetyl decapeptide-3HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%

Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.25–0.4%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.4–5.3%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.3–2.8%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.25–0.4%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.35%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.15–0.3%

Hydrolyzed yeast extractKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~0.2–0.35%

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%

PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1.1–1.3%

Punica granatum seed extractKey activeEffect: High~0.2–0.35%

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~3.1–3.8%

Hydrolyzed wheat proteinKey active· HumectantEffect: MediumCan help attract water to the upper layer of the skin. Avoid if sensitive to gluten~0.15–0.25%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~0.2–0.4%

Polyglyceryl-10 oleateKey activeEffect: MediumHelps soften the upper layer of the skin~0.15–0.3%

Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~1.9–2.3%

Ethylhexyl stearate· EmollientEffect: LowHelps soften the upper layer of the skin~0.25–0.5%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.2–0.4%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~5.9–7.2%

Calcium gluconate· HumectantEffect: LowHelps attract water to the upper layer of the skin and helps to improve appearance of the product~0.2–0.4%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.35%

Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.35–0.6%

Lactic acidUnder-dosedEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.4%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.4%

Exfoliation

Not advertised by the brand · Gluconolactone, Retinyl palmitate + 1 more

Strong evidence

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone.

Retinyl palmitateEffect: Low, below effective doseThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.15–0.25%

Evens skin tone

Not advertised by the brand · Gluconolactone, Hydrolyzed yeast extract + 2 more

Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Hydrolyzed yeast extractEffect: LowHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~0.2–0.35%

Anti-oxidation

Not advertised by the brand · Gluconolactone, Ginkgo biloba leaf extract + 7 more

Moderate evidence

This product contains antioxidants (ginkgo biloba leaf extract, gluconolactone) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

GluconolactoneKey activeEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.65–1%

Ginkgo biloba leaf extractKey activeEffect: MediumA plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating~0.25–0.4%

Punica granatum seed extractEffect: Low~0.2–0.35%

Vaccinium myrtillus fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking~0.15–0.3%

Hydrolyzed yeast extractEffect: LowHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties~0.2–0.35%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.3%

Panax ginseng root extractEffect: Low, below effective doseA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating~0.25–0.5%

Can it cause trouble?

Irritancy

4 strong irritants: Parfum, Retinyl palmitate + 2 more — patch-test recommended

High risk

We flagged 27 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.35–0.6%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.3–0.55%est.

Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.4–0.6%est.

Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.15–0.25%est.

Citrus limon fruit extractUsed as a fragrance. Can be irritating and cause photosensitivityHigh~0.2–0.35%est.

Citrus aurantium dulcis fruit extractA plant extract that is used as a fragrance. Can be irritating and lead to photosensitivityHigh~0.2–0.35%est.

Panax ginseng root extractA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritatingHigh~0.25–0.5%est.

Ginkgo biloba leaf extractA plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritatingHigh~0.25–0.4%est.

Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.2–0.4%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.65–1%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.2–0.4%est.

Vaccinium myrtillus fruit extractA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lackingMedium~0.15–0.3%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.3%est.

Hydrolyzed wheat proteinCan help attract water to the upper layer of the skin. Avoid if sensitive to glutenMedium~0.15–0.25%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.35%est.

Hexylene glycolHelps create a more spreadable product textureMedium~0.15–0.3%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.2–0.4%est.

Sorbitan palmitateHelps water and oil mix together and stabilize the product formulationMedium~0.2–0.4%est.

Sorbitan oleateHelps oil and water mix togetherMedium~0.2–0.4%est.

Acer saccharum extractA plant extract that contains small percentage of AHAs. Is unlikely to have any skin benefit due the small concentration of the active compoundsMedium~0.2–0.4%est.

Polysorbate 60Helps oil and water mix togetherMedium~0.25–0.5%est.

Polyglyceryl-4 diisostearate/polyhydroxystearate/sebacateHelps water and oil mix togetherMedium~0.25–0.45%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.25–0.45%est.

Disodium edtaStabilizes the product formulationMedium~0.2–0.4%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.25–0.4%est.

Sodium oleateHelps oil and water mix together and create a thicker product consistencyMedium~0.65–0.95%est.

Potassium sorbateA preservativeMedium~0.15–0.3%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~0.2–0.4%est.

Sorbitan oleateHelps oil and water mix together2/5~0.2–0.4%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.25–0.4%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Butylene glycol~5.9–7.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Dimethicone~4.4–5.3%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Cyclopentasiloxane~3.1–3.8%

Key active

Irritation risk: Low

Works for

MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Glycerin~2.3–2.8%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Polysilicone-11~1.9–2.3%

Formula

Irritation risk: Low

Works for

MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11

Octyldodecyl lactate~1.5–1.9%

Formula

Irritation risk: Low

More about Octyldodecyl lactate

Polyacrylate-13~1.4–1.7%

Formula

Irritation risk: Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13

Polymethylsilsesquioxane~1.1–1.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane

Gluconolactone~0.65–1%

Key activeIrritant · medium

Irritation risk: Medium

Works for

ExfoliationMoisturizingAnti-agingEvens skin toneAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Phenoxyethanol~0.5–0.75%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Polyisobutene~0.55–0.8%

Formula

Irritation risk: Low

Used to improve the product consistency

More about Polyisobutene

Propylene glycol~0.35–0.6%

Irritant · high

Irritation risk: High

Works for

Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol

Parfum~0.3–0.55%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Sodium benzoate~0.25–0.5%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Decyl glucoside~0.4–0.6%

Irritant · high

Irritation risk: High

Works for

Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside

Hydroxyethylcellulose~0.3–0.55%

Formula

Irritation risk: Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose

Lactic acid~0.2–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

ExfoliationEvens skin toneMoisturizingAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Polysorbate 20~0.25–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Sorbitan isostearate~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan isostearate

Vaccinium myrtillus fruit extract~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking

More about Vaccinium myrtillus fruit extract

Tocopheryl acetate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Apricot kernel oil polyglyceryl-6 esters~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

More about Apricot kernel oil polyglyceryl-6 esters

Retinyl palmitate~0.15–0.25%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate

Sodium hyaluronate~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Saccharum officinarum extract~0.15–0.25%

Key active

Irritation risk: Low

Works for

Moisturizing

Sugar extract that helps attract water to the upper layer of the skin

More about Saccharum officinarum extract

Polyglyceryl-10 dipalmitate~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

More about Polyglyceryl-10 dipalmitate

Hydrolyzed wheat protein~0.15–0.25%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Can help attract water to the upper layer of the skin. Avoid if sensitive to gluten

More about Hydrolyzed wheat protein

Helianthus annuus seed oil~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Sunflower seed oil polyglyceryl-6 esters~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sunflower seed oil polyglyceryl-6 esters

Polyglyceryl-10 oleate~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Polyglyceryl-10 oleate

Caprylyl glycol~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Hexylene glycol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol

Hydrolyzed hyaluronic acid~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Pentylene glycol~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Lecithin~0.2–0.4%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Ethylhexyl palmitate~0.2–0.4%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

Polyglyceryl-6 oleate~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

More about Polyglyceryl-6 oleate

Dicetyl phosphate~0.2–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

More about Dicetyl phosphate

Citrus limon fruit extract~0.2–0.35%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating and cause photosensitivity

More about Citrus limon fruit extract

Citrus aurantium dulcis fruit extract~0.2–0.35%

Irritant · high

Irritation risk: High

A plant extract that is used as a fragrance. Can be irritating and lead to photosensitivity

More about Citrus aurantium dulcis fruit extract

Calcium gluconate~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and helps to improve appearance of the product

More about Calcium gluconate

Maltodextrin~0.2–0.4%

Formula

Irritation risk: Low

Works for

Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin

Manilkara multinervis leaf extract~0.2–0.35%

Formula

Irritation risk: Low

More about Manilkara multinervis leaf extract

Sorbitan palmitate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together and stabilize the product formulation

More about Sorbitan palmitate

Punica granatum seed extract~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

More about Punica granatum seed extract

Hydrolyzed yeast extract~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties

More about Hydrolyzed yeast extract

Sorbitan oleate~0.2–0.4%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan oleate

Guanosine~0.2–0.4%

Formula

Irritation risk: Low

More about Guanosine

Uracil~0.2–0.4%

Formula

Irritation risk: Low

More about Uracil

Adenosine phosphate~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-agingAnti-inflammatory

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to stimulate collagen production in skin

More about Adenosine phosphate

Acer saccharum extract~0.2–0.4%

Irritant · medium

Irritation risk: Medium

A plant extract that contains small percentage of AHAs. Is unlikely to have any skin benefit due the small concentration of the active compounds

More about Acer saccharum extract

Ethylhexyl stearate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Ethylhexyl stearate

Kaempferol~0.25–0.5%

Formula

Irritation risk: Low

More about Kaempferol

Panax ginseng root extract~0.25–0.5%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatoryAnti-oxidation

A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating

More about Panax ginseng root extract

Magnolol~0.25–0.45%

Formula

Irritation risk: Low

More about Magnolol

Honokiol~0.2–0.4%

Formula

Irritation risk: Low

More about Honokiol

Ginkgo biloba leaf extract~0.25–0.4%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidationAnti-inflammatoryAnti-blemishAntibacterial

A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating

More about Ginkgo biloba leaf extract

Ulva lactuca extract~0.25–0.4%

Formula

Irritation risk: Low

More about Ulva lactuca extract

Hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Palmitoyl tripeptide-5~0.25–0.4%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Beta-glucan~0.25–0.4%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationAnti-agingAnti-blemishAnti-oxidation

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan

Tocopherol~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Polysorbate 60~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 60

Disodium phosphate~0.25–0.45%

Formula

Irritation risk: Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate

Sodium isostearate~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sodium isostearate

Polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate

Benzyl alcohol~0.2–0.4%

Irritant · high

Irritation risk: High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol

Sodium hyaluronate crosspolymer~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Silica dimethyl silylate~0.25–0.5%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Silica dimethyl silylate

Disodium edta~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Glycine soja oil~0.25–0.4%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Sodium oleate~0.65–0.95%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together and create a thicker product consistency

More about Sodium oleate

Hydrogenated lecithin~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Sodium phosphate~0.15–0.3%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Sodium phosphate

Potassium sorbate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Acetyl decapeptide-3~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl decapeptide-3

Sh-polypeptide-2~0.1–0.2%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-2

Sh-oligopeptide-1~0.1–0.2%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1

Ingredient list view

Water, Butylene glycol, Dimethicone, Cyclopentasiloxane, Glycerin, Polysilicone-11, Octyldodecyl lactate, Polyacrylate-13, Polymethylsilsesquioxane, Gluconolactone, Phenoxyethanol, Polyisobutene, Propylene glycol, Parfum, Sodium benzoate, Decyl glucoside, Hydroxyethylcellulose, Lactic acid, Polysorbate 20, Sorbitan isostearate, Vaccinium myrtillus fruit extract, Tocopheryl acetate, Apricot kernel oil polyglyceryl-6 esters, Retinyl palmitate, Sodium hyaluronate, Saccharum officinarum extract, Polyglyceryl-10 dipalmitate, Hydrolyzed wheat protein, Helianthus annuus seed oil, Sunflower seed oil polyglyceryl-6 esters, Polyglyceryl-10 oleate, Caprylyl glycol, Hexylene glycol, Hydrolyzed hyaluronic acid, Pentylene glycol, Lecithin, Ethylhexyl palmitate, Polyglyceryl-6 oleate, Dicetyl phosphate, Citrus limon fruit extract, Citrus aurantium dulcis fruit extract, Calcium gluconate, Maltodextrin, Manilkara multinervis leaf extract, Sorbitan palmitate, Punica granatum seed extract, Hydrolyzed yeast extract, Sorbitan oleate, Guanosine, Uracil, Adenosine phosphate, Acer saccharum extract, Ethylhexyl stearate, Kaempferol, Panax ginseng root extract, Magnolol, Honokiol, Ginkgo biloba leaf extract, Ulva lactuca extract, Hyaluronic acid, Palmitoyl tripeptide-5, Beta-glucan, Tocopherol, Polysorbate 60, Disodium phosphate, Sodium isostearate, Polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate, Benzyl alcohol, Sodium hyaluronate crosspolymer, Silica dimethyl silylate, Disodium edta, Glycine soja oil, Sodium oleate, Hydrogenated lecithin, Sodium phosphate, Potassium sorbate, Acetyl decapeptide-3, Sh-polypeptide-2, Sh-oligopeptide-1

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Product summary

"Swiss Clinic - Day Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (glycerin, hyaluronic acid, hydrolyzed hyaluronic acid, hydrolyzed yeast extract and sodium hyaluronate) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Glycine soja oil, dimethicone, helianthus annuus seed oil, cyclopentasiloxane and ethylhexyl palmitate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

This product contains acids (gluconolactone and lactic acid). Their concentration is low, and they will not have a strong exfoliating effect. Instead, they work to support the skin natural acid mantle and to attract water (as humectants). PHAs (gluconolactone) especially are great for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
This moisturizer includes a form of retinoids (vitamin A) - retinyl palmitate 0.15% - 0.25%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
We like that this moisturizer contains peptides (sh-oligopeptide-1 0.10% - 0.20%, palmitoyl tripeptide-5 0.25% - 0.40% and acetyl decapeptide-3 0.15% - 0.30%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 64.00$ in the United States, from 44.80£ up to 64.00£ in the United Kingdom and for 78.40CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 53 studies and safety reviews.

1
Dimethicone as a protective ingredient in topical medicationsjaad.org
2
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
3
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
4
A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acnencbi.nlm.nih.gov
5
The Polyhydroxy Acid Gluconolactone Protects Against Ultraviolet Radiation in an In Vitro Model of Cutaneous Photoagingonlinelibrary.wiley.com
6
Applications of hydroxy acids: classification, mechanisms, and photoactivityncbi.nlm.nih.gov
7
The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative studydovepress.com
8
A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimenncbi.nlm.nih.gov
9
The use of polyhydroxy acids (PHAs) in photoaged skin
10
Blackwell Publishing, Ltd. Alpha-hydroxyacids and carboxylic acidsonlinelibrary.wiley.com
11
An evaluation of a polyhydroxy acid skin care regimen in combination with azelaic acid 15% gel in rosacea patientsonlinelibrary.wiley.com
12
Aging Skin: Causes, Treatments, and Preventionsciencedirect.com
13
Clinical and cosmeceutical uses of hydroxyacidssciencedirect.com
14
Polyhydroxy Acids (PHAs) Provide Conditioning Effects to Skin Without Increasing Sensitivity to UV Lightneostrata.neogen.gr
15
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
16
Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
17
Propylene Glycolpubmed.ncbi.nlm.nih.gov
18
Skin-sensitizing and irritant properties of propylene glycolonlinelibrary.wiley.com
19
Ecofriendly surfactant is allergen of the yearmdedge.com
20
Epidermal and dermal effects of topical lactic acidncbi.nlm.nih.gov
21
Dual Effects of Alpha-Hydroxy Acids on the Skinpdfs.semanticscholar.org
22
Lonicera caerulea and Vaccinium myrtillus fruit polyphenols protect HaCaT keratinocytes against UVB-induced phototoxic stress and DNA damagesciencedirect.com
23
Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition.ncbi.nlm.nih.gov
24
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
25
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
26
Wheat in skin caremdedge.com
27
Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
28
Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
29
Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
30
Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
31
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
32
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
33
Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmeticscir-safety.org
34
Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmeticscir-safety.org
35
Photosensitivity in children: An approach to diagnosis and managementijdvl.com
36
The natural yeast extract isolated by ethanol precipitation inhibits melanin synthesis by modulating tyrosinase activity and downregulating melanosome transferncbi.nlm.nih.gov
37
Evaluation of dermatological effects of cosmetic formulations containing Saccharomyces cerevisiae extract and vitaminsresearchgate.net
38
Effects of adenosine 5'-monophosphate on epidermal turnoverncbi.nlm.nih.gov
39
Targeting adenosine receptors to prevent inflammatory skin diseasesncbi.nlm.nih.gov
40
Ginseng in Dermatology: A Reviewncbi.nlm.nih.gov
41
Antiaging effects of the mixture of Panax ginseng and Crataegus pinnatifida in human dermal fibroblasts and healthy human skinncbi.nlm.nih.gov
42
Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmeticscir-safety.org
43
Cosmeceutical Critique: Ginkgo Bilobamdedge.com
44
β-Glucans: Multi-Functional Modulator of Wound Healingncbi.nlm.nih.gov
45
Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucanonlinelibrary.wiley.com
46
Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Reviewonlinelibrary.wiley.com
47
Anticancer properties of low molecular weight oat beta-glucan – An in vitro studysciencedirect.com
48
A critical review on production and industrial applications 2 of beta-glucanssciencedirect.com
49
Improving skin function with CM-glucan, a biological response modifier from yeastonlinelibrary.wiley.com
50
Preparation, characterization, and biological properties of β-glucansncbi.nlm.nih.gov
51
Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatusncbi.nlm.nih.gov
52
Vitamin E in dermatologyncbi.nlm.nih.gov
53
Vitamin E and Skin Healthlpi.oregonstate.edu

Swiss ClinicDay Cream

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