skincode-Swiss Cellular Anti-Aging Cream

skincode-Swiss Cellular Anti-Aging Cream

Efficacy100/100IrritancyHigh
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Works for

2 of 2 advertised claims delivered

Moisturizing
Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, Palmitoyl hexapeptide-12 + 16 more
Strong evidence
What the product description says
“deeply nourishing moisturizer”
Source: Skincode

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, peg-8.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ng, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, palmitoyl hexapeptide-12, urea

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.3–0.55%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
Peg/ppg-18/18 dimethiconeKey activeEffect: HighA silicone that mixes with water creating nice light-weight product texture~1.3–1.6%
Phenyl trimethiconeKey active· OcclusiveEffect: HighA type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture~2.3–2.8%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~2.7–3.3%
Ceramide ngHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.55%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~6.7–8.2%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.55%
Coco-caprylate/caprateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin without creating a greasy texture~5.1–6.2%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~1.5–1.9%
C10-18 triglyceridesKey active· EmollientEffect: MediumHelps soften the skin and attract water to its upper layer. Helps create nice product texture~0.45–0.7%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~3.6–4.4%
Peg-8· HumectantEffect: LowUsed to create a nice product consistency~0.25–0.5%
Butyrospermum parkii butterUnder-dosedEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.35–0.6%
Lactic acidUnder-dosedEffect: HighAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.45%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.55%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–0.65%
Anti-aging
Palmitoyl hexapeptide-12, Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine + 5 more
Strong evidence
What the product description says
“anti-aging cream”
Source: Skincode

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonineKey activeEffect: Medium~0.95–1.15%
Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.35–0.65%
Lactic acidUnder-dosedEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.45%
Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.35–0.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–0.65%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.35–0.65%

Can it cause trouble?

Irritancy
3 strong irritants: Calendula officinalis flower extract, Alcohol + 1 more — patch-test recommended
High risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Calendula officinalis flower extractA plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritatingHigh~0.5–0.75%est.
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.35–0.65%est.
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.25–0.45%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.1%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.35–0.65%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.5%est.
Potassium sorbateA preservativeMedium~0.25–0.45%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.45%est.
Peg-8Used to create a nice product consistencyMedium~0.25–0.5%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.15–0.3%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.35–0.6%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Dimethicone~6.7–8.2%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Coco-caprylate/caprate~5.1–6.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin without creating a greasy texture

More about Coco-caprylate/caprate
Tribehenin~3.6–4.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Urea~2.7–3.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Phenyl trimethicone~2.3–2.8%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture

More about Phenyl trimethicone
Sodium chloride~1.9–2.3%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
C12-15 alkyl benzoate~1.5–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Peg/ppg-18/18 dimethicone~1.3–1.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A silicone that mixes with water creating nice light-weight product texture

More about Peg/ppg-18/18 dimethicone
Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine~0.95–1.15%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine
Palmitoyl dipeptide-5 diaminohydroxybutyrate~0.65–1%
Formula
Calendula officinalis flower extract~0.5–0.75%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that has some anti-oxidant and anti-bacterial properties. Can be irritating

More about Calendula officinalis flower extract
Hypericum perforatum extract~0.45–0.65%
Formula
C10-18 triglycerides~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the skin and attract water to its upper layer. Helps create nice product texture

More about C10-18 triglycerides
Tocopherol~0.4–0.65%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ascorbyl palmitate~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Ascorbic acid~0.35–0.65%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-agingEvens skin tone

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Palmitoyl hexapeptide-12~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Butyrospermum parkii butter~0.35–0.6%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Tocopheryl acetate~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Lecithin~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Ceramide ng~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ng
Potassium sorbate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Glycerin~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Helianthus annuus seed oil~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Lactic acid~0.25–0.45%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Peg-8~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a nice product consistency

More about Peg-8
Alcohol~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Polysorbate 80~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Soy isoflavones~0.2–0.35%
Formula
Citric acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Parfum~0.05–0.1%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Dimethicone, Coco-caprylate/caprate, Tribehenin, Urea, Phenyl trimethicone, Sodium chloride, C12-15 alkyl benzoate, Peg/ppg-18/18 dimethicone, Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, Palmitoyl dipeptide-5 diaminohydroxybutyrate, Calendula officinalis flower extract, Hypericum perforatum extract, C10-18 triglycerides, Tocopherol, Ascorbyl palmitate, Ascorbic acid, Palmitoyl hexapeptide-12, Butyrospermum parkii butter, Tocopheryl acetate, Lecithin, Ceramide ng, Potassium sorbate, Disodium edta, Glycerin, Helianthus annuus seed oil, Lactic acid, Peg-8, Alcohol, Polysorbate 80, Soy isoflavones, Citric acid, Phenoxyethanol, Sodium benzoate, Parfum

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Skincode
≈ $161.33
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
skincode-SwissCellular Anti-Aging CreamYOUR PRODUCTDermadoctorWrinkle Revenge Rescue & Protect Facial Cream
Match—50%
Price$162.55$38.95−$123.60
Shared key ingredients—5 of 12
Key difference—Linoleic Acid
Irritancy High Medium
Drying alcohol Contains drying alcohol —
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
    Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
  5. 5
  6. 6
skincode-Swiss Cellular Anti-Aging Cream
skincode-SwissCellular Anti-Aging Cream

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