Dermadoctor Wrinkle Revenge Rescue & Protect Facial Cream
Something wrong? Edit here- Anti-aging
- Moisturizing
- Evens skin tone
- tetrahexyldecyl ascorbate
- ceramide ng
- linoleic acid
- +17 more
FULFILLED

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Formula review
Promise
What does the product description say?WIMJ summary
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tripeptide-1, palmitoyl tripeptide-37, vitis vinifera seed extract.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
MEDIUM
| |||
MEDIUM
|
WIMJ summary
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glucosamine hcl.
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
MEDIUM
| |||
HIGH | |||
LOW
|
Promise
What does the product description say?WIMJ summary
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glucosamine hcl, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalene.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ng, linoleic acid, palmitoyl hexapeptide-12, palmitoyl tripeptide-1, palmitoyl tripeptide-37, urea
Ingredient | Effectiveness | Concentration | Irritancy |
---|---|---|---|
HIGH | |||
HIGH | |||
HIGH |
Potential irritants

Ingredient | Irritancy | Skin Benefit |
---|---|---|
polyglyceryl-2 stearate | ||
punica granatum fruit extract | ||
tetrahexyldecyl ascorbate |
Ingredients by volume
Ingredient | Estimated concentration |
---|---|
Plain old water
| 45% - 55% |
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
| 4.9% - 5.9% |
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
| 4.2% - 5.1% |
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Questions
Skincare resources
Scientific Sources
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmetics
- Glycerol and the skin: holistic approach to its origin and functions
- Squalene and its potential clinical uses
- Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology
- Enhanced comedo formation in rabbit ear skin by squalene and oleic acid peroxides
- Topical urea in skincare: A review
- Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory properties
- Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skin
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- Safety Assessment of Vitis Vinifera (Grape)-Derived Ingredients as Used in Cosmetics
- The Topical Effect of Grape Seed Extract 2% Cream on Surgery Wound Healing
- Review of the Pharmacological Effects of Vitis vinifera (Grape) and its Bioactive Constituents: An Update
- Phellodendron amurense Bark Extract
- Synergistic topical application of salt-processed Phellodendron amurense and Sanguisorba officinalis Linne alleviates atopic dermatitis symptoms by reducing levels of immunoglobulin E and pro-inflammatory cytokines in NC/Nga mice