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Dermadoctor Wrinkle Revenge Rescue & Protect Facial Cream
Dermadoctor

Dermadoctor Wrinkle Revenge Rescue & Protect Facial Cream

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Anti-aging
8 ingredients credited for this claim
Strong support
What the product description says
“Wrinkle Revenge Rescue & Protect Facial Cream”
From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tripeptide-1, palmitoyl tripeptide-37, vitis vinifera seed extract.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.65–1%
Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.3–0.5%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.9%
Palmitoyl tripeptide-37Key activeEffect: Medium~0.5–0.7%
Glucosamine hclEffect: LowMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.25–0.45%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.3–0.55%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.6%
Laminaria digitata extractEffect: Low, below effective doseSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.25–0.45%
Moisturizing
21 ingredients credited for this claim
Strong support
What the product description says
“Wrinkle Revenge Rescue & Protect Facial Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glucosamine hcl, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalene.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ng, palmitoyl hexapeptide-12, palmitoyl tripeptide-1, palmitoyl tripeptide-37, urea

Saccharomyces cerevisiae extractKey active· HumectantEffect: HighA moisturizing ingredient that works as a humectant to attract water to the upper layer of the skin.~0.2–0.4%
Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.15–0.25%
SqualeneKey active· Emollient, OcclusiveEffect: HighAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~1.3–1.5%
Ceramide ngHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.45–0.65%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~3.2–4%
Glucosamine hclKey active· HumectantEffect: HighMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.25–0.45%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.1–2.5%
Glycine soja sterolsKey active· EmollientEffect: HighAn emollient that helps soften the skin~0.25–0.5%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.65–1%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.9%
Palmitoyl tripeptide-37HeroEffect: High~0.5–0.7%
UreaHero· HumectantEffect: HighNaturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations~0.45–0.65%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.25–0.45%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~0.95–1.2%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~4.9–5.9%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.45–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4.2–5.1%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.45%
Linoleic acidUnder-dosedEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.35–0.65%
Laminaria digitata extractUnder-dosedEffect: MediumSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment~0.25–0.45%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.6%
Evens skin tone
Not advertised by the brand · 3 ingredients credited for this claim
Moderate support

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glucosamine hcl.

Glucosamine hclKey activeEffect: MediumMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.25–0.45%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.3–0.55%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.4–0.6%

Can it cause trouble?

Irritancy
2 strong irritants: Santalum album, Santalum album extract
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Punica granatum fruit extractA fruit extract that is used to add a fragrance to the product. It might have some antioxidant propertiesHigh~0.3–0.55%est.
Santalum album—High~0.2–0.4%est.
Santalum album extractUsed as a fragrance. Can be irritatingHigh~0.25–0.45%est.
Polyglyceryl-2 stearateHelps water and oil mix togetherMedium~2.3–2.8%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.3–0.55%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.5%est.
Phellodendron amurense bark extractA plant extract that might have an anti-inflammatory effectMedium~0.25–0.45%est.
Saccharomyces cerevisiae extractA moisturizing ingredient that works as a humectant to attract water to the upper layer of the skin.Medium~0.2–0.4%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.2–0.4%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.2–0.35%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.15–0.25%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.15–0.25%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Laminaria digitata extractSeaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment3/5~0.25–0.45%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~4.9–5.9%est.
SqualeneAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast2/5~1.3–1.5%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Cetearyl alcohol~4.9–5.9%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Butylene glycol~4.2–5.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dimethicone~3.2–4%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Polyglyceryl-2 stearate~2.3–2.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-2 stearate
Glycerin~2.1–2.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hordeum distichon extract~1.7–2.1%
Formula
Irritation risk
Low
More about Hordeum distichon extract
Cetearyl methicone~1.4–1.7%
Formula
Irritation risk
Low
More about Cetearyl methicone
Squalene~1.3–1.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
MoisturizingAnti-oxidation

An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast

More about Squalene
C12-15 alkyl benzoate~0.95–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Palmitoyl hexapeptide-12~0.65–1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Palmitoyl tripeptide-1~0.6–0.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tripeptide-37~0.5–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Palmitoyl tripeptide-37
Urea~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingExfoliation

Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations

More about Urea
Ceramide ng~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ng
Tribehenin~0.45–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Camellia sinensis leaf extract~0.4–0.6%
Formula
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingMoisturizingEvens skin toneAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Punica granatum fruit extract~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties

More about Punica granatum fruit extract
Tetrahexyldecyl ascorbate~0.3–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidationEvens skin tone

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate
Tocopheryl acetate~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Vitis vinifera seed extract~0.3–0.5%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract
Phellodendron amurense bark extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatory

A plant extract that might have an anti-inflammatory effect

More about Phellodendron amurense bark extract
Santalum album~0.2–0.4%
Irritant · high
Irritation risk
High
More about Santalum album
Santalum album extract~0.25–0.45%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Santalum album extract
Linoleic acid~0.35–0.65%
Under-dosed
Irritation risk
Low
Works for
MoisturizingCleansingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid
Phospholipids~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Glucosamine hcl~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAntibacterialEvens skin toneAnti-agingAnti-oxidation

Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.

More about Glucosamine hcl
Ammonium acryloyldimethyltaurate/vp copolymer~0.25–0.45%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Hydrogenated lecithin~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Glycine soja sterols~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin

More about Glycine soja sterols
Laminaria digitata extract~0.25–0.45%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

Seaweed extract that helps the skin to attract water and make it more smooth for touch. Also shows promise of anti-aging properties, but good research is lacking at the moment

More about Laminaria digitata extract
Saccharomyces cerevisiae extract~0.2–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A moisturizing ingredient that works as a humectant to attract water to the upper layer of the skin.

More about Saccharomyces cerevisiae extract
Caprylyl glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Hexylene glycol~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Peg-10 rapeseed sterol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-10 rapeseed sterol
Carbomer~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Sodium lactate~0.15–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Polysorbate 20~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Leuconostoc/radish root ferment filtrate~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Sodium hydroxide~0.1–0.15%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Cetearyl alcohol, Butylene glycol, Dimethicone, Polyglyceryl-2 stearate, Glycerin, Hordeum distichon extract, Cetearyl methicone, Squalene, C12-15 alkyl benzoate, Palmitoyl hexapeptide-12, Palmitoyl tripeptide-1, Palmitoyl tripeptide-37, Urea, Ceramide ng, Tribehenin, Camellia sinensis leaf extract, Punica granatum fruit extract, Tetrahexyldecyl ascorbate, Tocopheryl acetate, Vitis vinifera seed extract, Phellodendron amurense bark extract, Santalum album, Santalum album extract, Linoleic acid, Phospholipids, Glucosamine hcl, Ammonium acryloyldimethyltaurate/vp copolymer, Hydrogenated lecithin, Xanthan gum, Glycine soja sterols, Laminaria digitata extract, Saccharomyces cerevisiae extract, Caprylyl glycol, Ethylhexylglycerin, Hexylene glycol, Peg-10 rapeseed sterol, Carbomer, Sodium lactate, Polysorbate 20, Leuconostoc/radish root ferment filtrate, Sodium hydroxide, Phenoxyethanol

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Amazon USPrice as of 10/9/2026 21:05 GMT
$38.95
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$58.00
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Product summary

"Dermadoctor - Wrinkle Revenge Rescue & Protect Facial Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Urea, glucosamine hcl, glycerin, saccharomyces cerevisiae extract and sodium lactate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Ceramide ng, palmitoyl tripeptide-1, glycine soja sterols, dimethicone and squalene in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (ceramide ng 0.45% - 0.65%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • We like that this moisturizer contains peptides (palmitoyl tripeptide-37 0.50% - 0.70%, palmitoyl tripeptide-1 0.60% - 0.90% and palmitoyl hexapeptide-12 0.65% - 1.00%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Dermadoctor" is cruelty free and so is its parent company.

Price

The product retails from 64.69A$ up to 78.65A$ in Australia, for 58.00$ in the United States and for 47.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 20 studies and safety reviews.

  1. 1
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  2. 2
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  3. 3
    Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmeticscir-safety.org
  4. 4
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  5. 5
    Squalene and its potential clinical useseuropepmc.org
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Dermadoctor Wrinkle Revenge Rescue & Protect Facial Cream
DermadoctorWrinkle Revenge Rescue & Protect Facial Cream
Buy on Amazon$38.95 · as of 10/9 21:05 GMT

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Buy on Amazon$38.95 · as of 10/9 21:05 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.