skinChemists Professional Pro-5 Collagen Age Defy Serum

skinChemists Professional Pro-5 Collagen Age Defy Serum

Efficacy91/100IrritancyHigh

Works for

Evens skin tone
Retinol
Works well
What the product description says
“Plant-derived Collagen helps to even the skin tone and increase elasticity, Marine Amino Acids enhance suppleness and bounce in the skin, and the addition of Anti-pollution Complex protects against environmental aggressors which can visibly age our appearance.”
Source: skinChemists

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
Anti-aging
Retinol, Tocopherol
Works well
What the product description says
“Pro-5 Collagen Age Defy Serum”
Source: skinChemists

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%
Moisturizing
Glycerin, Cyclopentasiloxane + 9 more
Works
What the product description says
“Our Pro-5 Collagen Age Defy Serum works hard all day and night to plump, hydrate and renew your skin.”
Source: skinChemists

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.4–5.1%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1.3–1.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.5–1.15%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.4–1%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.75%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~4.6–6.9%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~1.7–2.6%
C13-14 isoparaffin· EmollientEffect: LowHelps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency~1.4–2.2%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~1.1–1.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.9%
Anti-oxidation
Not advertised by the brand · Retinol, Tocopherol
Works well

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%
Exfoliation
Not advertised by the brand · Retinol, Allantoin
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.9%
Anti-blemish
Not advertised by the brand · Retinol, Allantoin
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.4–0.9%

Can it cause trouble?

Irritancy
7 strong irritants: Retinol, Parfum + 5 more — patch-test recommended
High risk
We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~4.6–6.9%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.5–1%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.3–0.75%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.35%est.
Benzyl salicylateA fragrance. Is a likely irritantHigh~0.05–0.25%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.05–0.25%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.05–0.15%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.
CitronellolA fragrance. Can be irritatingHigh~0.01–0.05%est.
PolyacrylamideUsed to improve product texture and help oil and water mix togetherMedium~2.1–3.1%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~1.7–2.6%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.4–1%est.
Laureth-7Helps oil and water mix togetherMedium~0.35–0.85%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.75%est.
EthylhexylglycerinA preservativeMedium~0.15–0.5%est.
Dehydroacetic acidA preservativeMedium~0.1–0.4%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Propylene glycol~4.6–6.9%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Glycerin~3.4–5.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hdi/trimethylol hexyllactone crosspolymer~2.7–4%
Formula
Irritation risk
Low

Used to create a silky product texture and add volume to products

More about Hdi/trimethylol hexyllactone crosspolymer
Polyacrylamide~2.1–3.1%
Irritant · medium
Irritation risk
Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide
Hydroxypropyl cyclodextrin~1.7–2.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
C13-14 isoparaffin~1.4–2.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Cyclopentasiloxane~1.3–1.9%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Polysilicone-11~1.1–1.6%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Phenoxyethanol~0.5–1%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Benzyl alcohol~0.5–1%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Dimethicone~0.5–1.15%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Allantoin~0.4–0.9%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Caprylic/capric triglyceride~0.4–1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Laureth-7~0.35–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Retinol~0.3–0.75%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingMattifyingExfoliationAnti-oxidationAnti-blemish

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Sodium hyaluronate~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Disodium edta~0.2–0.75%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Silica~0.3–0.75%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Ethylhexylglycerin~0.15–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Dehydroacetic acid~0.1–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Dehydroacetic acid
Parfum~0.1–0.35%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Tocopherol~0.1–0.35%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Benzyl salicylate~0.05–0.25%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Benzyl salicylate
Hexyl cinnamal~0.05–0.25%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Limonene~0.05–0.15%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Citronellol~0.01–0.05%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Ingredient list view

Water, Propylene glycol, Glycerin, Hdi/trimethylol hexyllactone crosspolymer, Polyacrylamide, Hydroxypropyl cyclodextrin, C13-14 isoparaffin, Cyclopentasiloxane, Polysilicone-11, Phenoxyethanol, Benzyl alcohol, Dimethicone, Allantoin, Caprylic/capric triglyceride, Laureth-7, Retinol, Sodium hyaluronate, Disodium edta, Silica, Ethylhexylglycerin, Dehydroacetic acid, Parfum, Tocopherol, Benzyl salicylate, Hexyl cinnamal, Limonene, Linalool, Citronellol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
skinChemists ProfessionalPro-5 Collagen Age Defy SerumYOUR PRODUCTskinChemistsAdvanced Retinol SerumDiorCapture Totale Retishot Retinol Night TreatmentIOPERetinol Expert 0.1%
Match—100%96%96%
Price—$19.39$120.00$80.00
Shared key ingredients—7 of 87 of 87 of 8
Key difference——Acetyl Tetrapeptide-11Acetyl Tetrapeptide-11
Irritancy High High Medium Medium
Drying alcohol————
View product Shop Shop Shop

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Product summary

"skinChemists Professional - Pro-5 Collagen Age Defy Serum" is effective for: Anti-aging, Evens skin tone, Exfoliation and Anti-blemish

This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • this product contains an effective form of Retinoids (vitamin A): retinol 0.30% - 0.75%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
  • Humectants (sodium hyaluronate 0.30% - 0.75% and glycerin 3.40% - 5.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
  2. 2
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
  3. 3
  4. 4
  5. 5
  6. 6
skinChemists Professional Pro-5 Collagen Age Defy Serum
skinChemists ProfessionalPro-5 Collagen Age Defy Serum

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