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Sesderma Retiage Face Cream
Sesderma

Sesderma Retiage Face Cream

Efficacy100/100IrritancyHigh
See all ingredients In 4 routines
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Works for

2 of 2 advertised claims delivered

Moisturizing
Caprooyl tetrapeptide-3, Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40 + 15 more
Strong evidence
What the product description says
“Retiage Face Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: dextran, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: caprooyl tetrapeptide-3

Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40Key activeEffect: High~0.3–0.55%
Caprooyl tetrapeptide-3Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.2–0.35%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.25–0.45%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.9–2.3%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.4%
Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~0.2–0.35%
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76Key activeEffect: HighA fusion peptide that combines peptides produced by human and plant cells. It might have anti-aging effect in skin and can help the skin moisturization~0.3–0.55%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~1.4–1.7%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1.6–1.9%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.95–1.15%
Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~5.2–6.3%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.1–1.4%
Cetearyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin~4.1–5.1%
CyclohexasiloxaneEffect: Low, below effective doseA silicone that serves as an emollient. Helps create a nice non-greasy feels~0.25–0.45%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%
Anti-aging
Retinal, Retinol + 7 more
Strong evidence
What the product description says
“Glycerin helps lock in a layer of moisture, supporting a supple, youthful-looking visage.”
Source: Lookfantastic CA

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinal, retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: caprooyl tetrapeptide-3, retinyl propionate.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.2–0.35%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.3%
Caprooyl tetrapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Retinyl propionateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores, even thought its potency is not as well established as in case of retinol or retinaldehyde~0.2–0.35%
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76Effect: LowA fusion peptide that combines peptides produced by human and plant cells. It might have anti-aging effect in skin and can help the skin moisturization~0.3–0.55%
Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40Effect: Low~0.3–0.55%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~1.4–1.7%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.25–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Exfoliation
Not advertised by the brand · Retinol
Strong evidence

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.3%
Anti-blemish
Not advertised by the brand · Retinol, Retinal + 1 more
Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinal, retinol. These ingredients is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: retinyl propionate

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.3%
RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.2–0.35%
Retinyl propionateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores, even thought its potency is not as well established as in case of retinol or retinaldehyde~0.2–0.35%
Anti-oxidation
Not advertised by the brand · Retinol, Resveratrol dimethyl ether + 4 more
Strong evidence

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.3%
Resveratrol dimethyl etherEffect: LowA more stable derivative of anti-oxidant resveratrol. There is not enough research to confirm its efficacy in skin~0.2–0.35%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~1.4–1.7%
ErgothioneineUnder-dosedEffect: HighCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.2–0.35%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.25–0.5%
Evens skin tone
Not advertised by the brand · Retinal, Retinol + 3 more
Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinal, retinol.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: resveratrol dimethyl ether, retinyl propionate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinalHeroEffect: HighOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating~0.2–0.35%
RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.15–0.3%
Retinyl propionateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores, even thought its potency is not as well established as in case of retinol or retinaldehyde~0.2–0.35%
Resveratrol dimethyl etherEffect: LowA more stable derivative of anti-oxidant resveratrol. There is not enough research to confirm its efficacy in skin~0.2–0.35%
Ascorbyl glucosideUnder-dosedEffect: MediumA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.25–0.5%

Can it cause trouble?

Irritancy
5 strong irritants: Alcohol, Parfum + 3 more — patch-test recommended
High risk
We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.3–0.55%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.3%est.
RetinalOne step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritatingHigh~0.2–0.35%est.
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.15–0.3%est.
Retinyl propionateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores, even thought its potency is not as well established as in case of retinol or retinaldehydeHigh~0.2–0.35%est.
Glyceryl behenateUsed to create a thicker product consistency and help soften the upper layer of the skinMedium~0.55–0.8%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.45–0.7%est.
Ascorbyl glucosideA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsMedium~0.25–0.5%est.
BhaHelps preserve the product formulationMedium~0.25–0.45%est.
BhtA preservativeMedium~0.2–0.4%est.
Ceteth-20Helps water and oil mix togetherMedium~0.3–0.6%est.
Ci 17200A red colorantMedium~0.2–0.4%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.35%est.
EthylhexylglycerinA preservativeMedium~0.2–0.35%est.
Peg-75 stearateHelps water and oil mix togetherMedium~0.2–0.4%est.
Steareth-20Helps oil and water mix togetherMedium~0.2–0.4%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.1–0.2%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Alternatives
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Hydrogenated polydecene~5.2–6.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene
Cetearyl ethylhexanoate~4.1–5.1%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin

More about Cetearyl ethylhexanoate
Sorbitan stearate~2.7–3.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan stearate
Propanediol~2.2–2.7%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Glycerin~1.9–2.3%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cyclopentasiloxane~1.6–1.9%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Prunus amygdalus dulcis oil~1.4–1.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Glyceryl stearate~1.1–1.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Cetyl alcohol~0.95–1.15%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Polymethyl methacrylate~0.65–0.95%
Formula
Irritation risk
Low

Is used to enhance product texture and can help to optically mask skin imperfections

More about Polymethyl methacrylate
Glyceryl behenate~0.55–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency and help soften the upper layer of the skin

More about Glyceryl behenate
Acrylates/c10-30 alkyl acrylate crosspolymer~0.45–0.7%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Dimethicone/vinyl dimethicone crosspolymer~0.35–0.65%
Formula
Irritation risk
Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76~0.3–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A fusion peptide that combines peptides produced by human and plant cells. It might have anti-aging effect in skin and can help the skin moisturization

More about Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76
Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40~0.3–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40
Alcohol~0.3–0.55%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Ascorbyl glucoside~0.25–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidationEvens skin tone

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Has a potential to boost collagen production, nutralise free radicals and reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about Ascorbyl glucoside
Bha~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Helps preserve the product formulation

More about Bha
Bht~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Caprooyl tetrapeptide-3~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Caprooyl tetrapeptide-3
Ceteth-20~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteth-20
Ci 17200~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A red colorant

More about Ci 17200
Cyclohexasiloxane~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Dextran~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Dimethicone~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Dipotassium phosphate~0.2–0.35%
Formula
Irritation risk
Low

Used to adjust the pH of the product

More about Dipotassium phosphate
Disodium edta~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Tocopherol~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryMoisturizingAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ergothioneine~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine
Ethylhexylglycerin~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Helianthus annuus seed oil~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Hydrochloric acid~0.2–0.35%
Formula
Irritation risk
Low
More about Hydrochloric acid
Hydrolyzed sodium hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate
Lecithin~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Parfum~0.15–0.3%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Peg-75 stearate~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Peg-75 stearate
Phenoxyethanol~0.2–0.4%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polysorbate 20~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Potassium phosphate~0.2–0.35%
Formula
Irritation risk
Low

Helps regulate the pH of the formulation

More about Potassium phosphate
Resveratrol dimethyl ether~0.2–0.35%
Formula
Irritation risk
Low
Works for
Anti-oxidationEvens skin tone

A more stable derivative of anti-oxidant resveratrol. There is not enough research to confirm its efficacy in skin

More about Resveratrol dimethyl ether
Retinal~0.2–0.35%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingAnti-blemish

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

More about Retinal
Retinol~0.15–0.3%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
ExfoliationAnti-oxidationAnti-agingEvens skin toneAnti-blemishMattifying

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Retinyl propionate~0.2–0.35%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-agingAnti-blemishEvens skin tone

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores, even thought its potency is not as well established as in case of retinol or retinaldehyde

More about Retinyl propionate
Sodium chloride~0.2–0.35%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Sodium cholate~0.15–0.25%
Formula
Irritation risk
Low
More about Sodium cholate
Sodium hydroxide~0.1–0.2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Steareth-20~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-20
Triethanolamine~0.1–0.2%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Xanthan gum~0.05–0.1%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Zinc chloride~0.05–0.1%
Formula
Irritation risk
Low
More about Zinc chloride
Ingredient list view

Water, Hydrogenated polydecene, Cetearyl ethylhexanoate, Sorbitan stearate, Propanediol, Glycerin, Cyclopentasiloxane, Prunus amygdalus dulcis oil, Glyceryl stearate, Cetyl alcohol, Polymethyl methacrylate, Glyceryl behenate, Acrylates/c10-30 alkyl acrylate crosspolymer, Dimethicone/vinyl dimethicone crosspolymer, Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76, Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40, Alcohol, Ascorbyl glucoside, Bha, Bht, Caprooyl tetrapeptide-3, Ceteth-20, Ci 17200, Cyclohexasiloxane, Dextran, Dimethicone, Dipotassium phosphate, Disodium edta, Tocopherol, Ergothioneine, Ethylhexylglycerin, Helianthus annuus seed oil, Hydrochloric acid, Hydrolyzed sodium hyaluronate, Lecithin, Parfum, Peg-75 stearate, Phenoxyethanol, Polysorbate 20, Potassium phosphate, Resveratrol dimethyl ether, Retinal, Retinol, Retinyl propionate, Sodium chloride, Sodium cholate, Sodium hydroxide, Steareth-20, Triethanolamine, Xanthan gum, Zinc chloride

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Amazon USPrice as of 10/23/2026 21:24 GMT
$72.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
SesdermaRetiage Face CreamYOUR PRODUCTSkincare by Dr VHPC CLEAR CreamStriVectinAdvanced Retinol Nightly Renewal MoisturizerSCINICCicanoid Retinal Cream
Match—72%72%71%
Price$42.60$2783.28+$2740.68$39.50−$3.10$22.30−$20.30
Shared key ingredients—4 of 145 of 144 of 14
Key difference—Salicylic AcidVitamin CNiacinamide
Irritancy High High High High
Drying alcohol Contains drying alcohol ———
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Product summary

Judging from the ingredient list, "Sesderma - Retiage Face Cream" works well for improving skin hydration The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Dextran and glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Caprooyl tetrapeptide-3, dimethicone, helianthus annuus seed oil, cetyl alcohol and cyclopentasiloxane in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • this moisturizer contains an effective form of retinoids (vitamin A): retinol 0.15% - 0.30% and retinal 0.20% - 0.35%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of retinoids is that they can be irritating. If you are not already using a retinoid in your routine, it is best to start slowly and apply the retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternative days or when your skin feels dry.
  • We like that this moisturizer contains peptides (caprooyl tetrapeptide-3 0.25% - 0.45%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 55.20$ in the United States, for 70.00CA$ in Canada and for 40.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 21 studies and safety reviews.

  1. 1
    Safety Assessment of Polyene Group as Used in Cosmeticscir-safety.org
  2. 2
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  3. 3
    Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oilsmdpi.com
  4. 4
    The Roles of Vitamin C in Skin Healthncbi.nlm.nih.gov
  5. 5
    Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivativesncbi.nlm.nih.gov
  6. 6
    Dimethicone as a protective ingredient in topical medicationsjaad.org
Sesderma Retiage Face Cream
SesdermaRetiage Face Cream
Buy on Amazon$72.00 · as of 10/23 21:24 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$72.00 · as of 10/23 21:24 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.