SBS InterFuse Treatment Cream FACE & NECK | skinbetter science

SBS InterFuse Treatment Cream FACE & NECK | skinbetter science

Efficacy75/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Anti-aging
6 ingredients credited for this claim
Moderate support
What the product description says
“Why You'll Love It: Improves the appearance of skin sagging, firmness, lines and wrinkles, and loss of elasticity.”
Source: SkinBetter

This product contains acetyl dipeptide-1 cetyl ester, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl dipeptide-1 cetyl esterKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.9%
Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.65%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.6–2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.15%
Moisturizing
Not advertised by the brand · 18 ingredients credited for this claim
Strong support

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium lactate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl dipeptide-1 cetyl ester, dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1

Acetyl dipeptide-1 cetyl esterHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–0.9%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.6–2%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.65%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.1–5%
Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.15–0.25%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~3.1–3.8%
Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.8–5.8%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.25–0.45%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.25–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.5%
C15-19 alkaneEffect: LowHelps soften the upper layer of the skin and create a nice product texture~2.2–2.7%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~1.1–1.4%
Olea europaea fruit extract· EmollientEffect: LowAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.95–1.15%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.1–0.15%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.15%

Can it cause trouble?

Irritancy
1 strong irritant: Alcohol denat.
Medium risk
We flagged 10 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~1.4–1.7%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.35–0.6%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
Ceteth-20Helps water and oil mix togetherMedium~0.3–0.6%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.
EthylhexylglycerinA preservativeMedium~0.2–0.35%est.
Peg-75 stearateHelps water and oil mix togetherMedium~0.2–0.35%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.15–0.25%est.
Sorbitan laurateHelps water and oil mix togetherMedium~0.15–0.25%est.
Steareth-20Helps oil and water mix togetherMedium~0.2–0.35%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.6–2%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.8–5.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~4.1–5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Squalane~3.1–3.8%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
C15-19 alkane~2.2–2.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product texture

More about C15-19 alkane
Peg-16 macadamia glycerides~1.9–2.3%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-16 macadamia glycerides
Butyrospermum parkii butter~1.6–2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Alcohol denat.~1.4–1.7%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Octyldodecanol~1.1–1.4%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Olea europaea fruit extract~0.95–1.15%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit extract
Acetyl dipeptide-1 cetyl ester~0.6–0.9%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatoryAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester
Dipeptide diaminobutyroyl benzylamide diacetate~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate
Palmitoyl tetrapeptide-7~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Palmitoyl tripeptide-1~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Sodium hydroxide~0.35–0.6%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Tetrasodium glutamate diacetate~0.3–0.6%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Acrylates/c10-30 alkyl acrylate crosspolymer~0.35–0.6%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Ammonium acryloyldimethyltaurate/vp copolymer~0.3–0.55%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Butylene glycol~0.25–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Carbomer~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Ceteth-20~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteth-20
Cetyl alcohol~0.25–0.45%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Titanium dioxide~0.3–0.55%
Formula
Irritation risk
Low
Works for
Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide
Citric acid~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ethylhexylglycerin~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Glyceryl stearate~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Hydroxyethylcellulose~0.2–0.35%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Mica~0.2–0.4%
Formula
Irritation risk
Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica
Peg-75 stearate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Peg-75 stearate
Polysorbate 20~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Sodium lactate~0.15–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Sorbitan laurate~0.15–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan laurate
Steareth-20~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-20
Tocopherol~0.1–0.15%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Polysilicone-11~0.1–0.15%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Phenoxyethanol~0.05–0.15%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Glycerin, Dimethicone, Squalane, C15-19 alkane, Peg-16 macadamia glycerides, Butyrospermum parkii butter, Alcohol denat., Octyldodecanol, Olea europaea fruit extract, Acetyl dipeptide-1 cetyl ester, Dipeptide diaminobutyroyl benzylamide diacetate, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Sodium hydroxide, Tetrasodium glutamate diacetate, Acrylates/c10-30 alkyl acrylate crosspolymer, Ammonium acryloyldimethyltaurate/vp copolymer, Butylene glycol, Caprylyl glycol, Carbomer, Ceteth-20, Cetyl alcohol, Titanium dioxide, Citric acid, Ethylhexylglycerin, Glyceryl stearate, Hydroxyethylcellulose, Mica, Peg-75 stearate, Polysorbate 20, Sodium lactate, Sorbitan laurate, Steareth-20, Tocopherol, Polysilicone-11, Phenoxyethanol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
SBSInterFuse Treatment Cream FACE & NECK | skinbetter scienceYOUR PRODUCTPeter Thomas RothPeptide Skinjection™ Moisture Infusion Refillable CreamPayotPerform Lift Reinforcing and Lifting Day Rich CreamNo7Pure Retinol Night Repair Cream
Match—57%54%53%
Price—$55.00$88.58$30.00
Shared key ingredients—8 of 117 of 116 of 11
Key difference—Tripeptide-1Mineral OilRetinol
Irritancy Medium Medium Medium Medium
Drying alcohol Contains drying alcohol —— Contains drying alcohol
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 5 studies and safety reviews.

  1. 1
  2. 2
  3. 3
  4. 4
    Vitamin E in dermatologyncbi.nlm.nih.gov
  5. 5
    Vitamin E and Skin Healthlpi.oregonstate.edu
SBS InterFuse Treatment Cream FACE & NECK | skinbetter science
SBSInterFuse Treatment Cream FACE & NECK | skinbetter science

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