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DRMTLGY Advanced Neck Cream
DRMTLGY

DRMTLGY Advanced Neck Cream

Efficacy87/100IrritancyMedium
See all ingredients In 3 routines
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Works for

2 of 2 advertised claims delivered

Moisturizing
27 ingredients credited for this claim
Strong support
What the product description says
“This gentle formula promotes hydrated skin and a healthier moisture barrier, resulting in a visibly smoother and firmer neck.”
Source: drmtlgy

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl dipeptide-1 cetyl ester, ceramide ap, ceramide eop, ceramide np, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, phytosphingosine, trifluoroacetyl tripeptide-2

Acetyl dipeptide-1 cetyl esterHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.45%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.7%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.4–0.95%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.75%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.75%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.8%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.6%
PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.2–0.8%
Prunus amygdalus dulcis seed extractKey activeEffect: HighAlmond extract (oil) - helps soften the upper layer of the skin~0.15–0.6%
Secale cereale seed extractKey activeEffect: HighRye seed extract. Helps soften the upper layer of the skin~0.3–0.7%
Trifluoroacetyl tripeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.8–4.2%
Triticum vulgare germ oilKey active· EmollientEffect: HighA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).~0.2–0.75%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.7%
Ceramide apHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.75%
Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.75%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.8%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~0.35–0.85%
Pyrus malus fruit extractKey activeEffect: MediumCan have some moisturizing properties due to its sugar content~0.15–0.6%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.3–0.75%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.35–0.75%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~0.2–0.75%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.3–1.9%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.2–0.7%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.2–0.8%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.7%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~0.35–0.85%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.6%
Anti-aging
8 ingredients credited for this claim
Moderate support
What the product description says
“Targets dryness and signs of premature skin aging”
Source: drmtlgy

This product contains acetyl dipeptide-1 cetyl ester, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, trifluoroacetyl tripeptide-2. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Trifluoroacetyl tripeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.8–4.2%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.8%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.6%
Acetyl dipeptide-1 cetyl esterKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.45%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.75%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.7%
TocopherolEffect: LowPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.3–1.9%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.2–0.75%
Anti-oxidation
Not advertised by the brand · 6 ingredients credited for this claim
Strong support

This product contains antioxidants (tocopherol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

TocopherolKey activeEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~1.3–1.9%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.7%
Pyrus malus fruit extractEffect: LowCan have some moisturizing properties due to its sugar content~0.15–0.6%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.2–0.75%
Triticum vulgare germ oilEffect: LowA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).~0.2–0.75%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.65%

Can it cause trouble?

Irritancy
11 flagged ingredients
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Pyrus malus fruit extractCan have some moisturizing properties due to its sugar contentMedium~0.9–1.3%est.
Secale cereale seed extractRye seed extract. Helps soften the upper layer of the skinMedium~0.5–1.15%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~0.35–0.85%est.
Glycol distearateHelps water and oil mix togetherMedium~0.3–0.7%est.
Sodium lauroyl lactylateHelps water and oil mix togetherMedium~0.15–0.65%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.65%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.2–0.8%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.3–0.7%est.
EthylhexylglycerinA preservativeMedium~0.15–0.6%est.
Sorbitan laurateHelps water and oil mix togetherMedium~0.15–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.5%est.
Comedogenic
6 ingredients rated 2 or more on the 0–5 pore-clogging scale
6 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.4–2%est.
Triticum vulgare germ oilA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).3/5~0.6–1.35%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~0.35–0.85%est.
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.3–0.7%est.
Triticum vulgare germ oilA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).3/5~0.2–0.75%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.75%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Ceramide np~22–33%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Ceramide ap~4.3–6.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ap
Ceramide eop~5.1–7.7%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide eop
Palmitoyl tripeptide-5~3.9–5.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Trifluoroacetyl tripeptide-2~2.8–4.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Trifluoroacetyl tripeptide-2
Palmitoyl tripeptide-1~2.2–3.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tetrapeptide-7~1.7–2.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Tocopherol~1.3–1.9%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Butyrospermum parkii butter~1.4–2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Pyrus malus fruit extract~0.9–1.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Triticum vulgare germ oil~0.6–1.35%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

A good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).

More about Triticum vulgare germ oil
Prunus amygdalus dulcis oil~0.5–1.15%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Nelumbo nucifera leaf extract~0.4–0.9%
Formula
Irritation risk
Low
More about Nelumbo nucifera leaf extract
Secale cereale seed extract~0.5–1.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Rye seed extract. Helps soften the upper layer of the skin

More about Secale cereale seed extract
Water~0.35–0.8%
Formula
Irritation risk
Low

Plain old water

More about Water
Dimethicone~0.4–0.95%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Isopropyl palmitate~0.35–0.85%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
C12-15 alkyl benzoate~0.35–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Glycerin~0.3–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~0.2–0.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Cetyl alcohol~0.35–0.75%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Cetearyl alcohol~0.3–0.75%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Butyrospermum parkii butter~0.3–0.7%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Pyrus malus fruit extract~0.15–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Peg-100 stearate~0.3–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Glycol distearate~0.3–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Glycol distearate
Glyceryl stearate~0.3–0.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Triticum vulgare germ oil~0.2–0.75%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

A good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).

More about Triticum vulgare germ oil
Prunus amygdalus dulcis oil~0.2–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Ceramide np~0.2–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Ceramide ap~0.2–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ap
Ceramide eop~0.2–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide eop
Phytosphingosine~0.2–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine
Cholesterol~0.3–0.7%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Sodium lauroyl lactylate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Sodium lauroyl lactylate
Xanthan gum~0.15–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Palmitoyl tripeptide-5~0.15–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Phenoxyethanol~0.15–0.65%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Tocopheryl acetate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Pentylene glycol~0.2–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Prunus amygdalus dulcis seed extract~0.15–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Almond extract (oil) - helps soften the upper layer of the skin

More about Prunus amygdalus dulcis seed extract
Acrylates/c10-30 alkyl acrylate crosspolymer~0.3–0.7%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Dimethicone/vinyl dimethicone crosspolymer~0.15–0.65%
Formula
Irritation risk
Low

Used to stabilize product formulations and create a nice product texture

More about Dimethicone/vinyl dimethicone crosspolymer
Sodium polystyrene sulfonate~0.3–0.7%
Formula
Irritation risk
Low
Works for
Cleansing
More about Sodium polystyrene sulfonate
Sorghum bicolor stalk juice~0.15–0.6%
Formula
Irritation risk
Low
More about Sorghum bicolor stalk juice
Ethylhexylglycerin~0.15–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Secale cereale seed extract~0.3–0.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Rye seed extract. Helps soften the upper layer of the skin

More about Secale cereale seed extract
Allantoin~0.15–0.6%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Sorbitan laurate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan laurate
Palmitoyl tripeptide-1~0.2–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tetrapeptide-7~0.2–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Polysorbate 20~0.15–0.65%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Sodium hydroxide~0.15–0.6%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
3-aminopropane sulfonic acid~0.15–0.55%
Formula
Irritation risk
Low
Works for
Cleansing
More about 3-aminopropane sulfonic acid
Calcium hydroxymethionine~0.15–0.6%
Formula
Irritation risk
Low
More about Calcium hydroxymethionine
Disodium edta~0.1–0.5%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Hydroxyethylcellulose~0.15–0.6%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Nelumbo nucifera leaf extract~0.15–0.55%
Formula
Irritation risk
Low
More about Nelumbo nucifera leaf extract
Acetyl dipeptide-1 cetyl ester~0.1–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatoryAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester
Carbomer~0.1–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Tripeptide-2~0.1–0.4%
Formula
Irritation risk
Low
More about Tripeptide-2
Ingredient list view

Ceramide np, Ceramide ap, Ceramide eop, Palmitoyl tripeptide-5, Trifluoroacetyl tripeptide-2, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Tocopherol, Butyrospermum parkii butter, Pyrus malus fruit extract, Triticum vulgare germ oil, Prunus amygdalus dulcis oil, Nelumbo nucifera leaf extract, Secale cereale seed extract, Water, Dimethicone, Isopropyl palmitate, C12-15 alkyl benzoate, Glycerin, Butylene glycol, Cetyl alcohol, Cetearyl alcohol, Butyrospermum parkii butter, Pyrus malus fruit extract, Peg-100 stearate, Glycol distearate, Glyceryl stearate, Triticum vulgare germ oil, Prunus amygdalus dulcis oil, Ceramide np, Ceramide ap, Ceramide eop, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Xanthan gum, Palmitoyl tripeptide-5, Phenoxyethanol, Tocopheryl acetate, Pentylene glycol, Prunus amygdalus dulcis seed extract, Acrylates/c10-30 alkyl acrylate crosspolymer, Dimethicone/vinyl dimethicone crosspolymer, Sodium polystyrene sulfonate, Sorghum bicolor stalk juice, Ethylhexylglycerin, Secale cereale seed extract, Allantoin, Sorbitan laurate, Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7, Polysorbate 20, Sodium hydroxide, 3-aminopropane sulfonic acid, Calcium hydroxymethionine, Disodium edta, Hydroxyethylcellulose, Nelumbo nucifera leaf extract, Acetyl dipeptide-1 cetyl ester, Carbomer, Tripeptide-2

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Amazon USPrice as of 10/19/2026 12:05 GMT
$54.00
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drmtlgy
≈ $66.11
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Product summary

Based on the ingredients included, "DRMTLGY - Advanced Neck Cream" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (dextran, glycerin and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide eop, ceramide np, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1 and phytosphingosine in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (phytosphingosine 0.20% - 0.80%, ceramide np 22.00% - 33.00%, ceramide eop 5.10% - 7.70%, ceramide ap 4.40% - 6.60%, ceramide np 0.20% - 0.80%, ceramide eop 0.20% - 0.75% and ceramide ap 0.15% - 0.60%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • We like that this moisturizer contains peptides (trifluoroacetyl tripeptide-2 2.80% - 4.20%, palmitoyl tetrapeptide-7 0.20% - 0.75%, palmitoyl tetrapeptide-7 1.70% - 2.60%, trifluoroacetyl tripeptide-2 0.15% - 0.60%, palmitoyl tripeptide-5 0.15% - 0.60%, palmitoyl tripeptide-5 3.90% - 5.90%, palmitoyl tripeptide-1 0.20% - 0.80%, palmitoyl tripeptide-1 2.20% - 3.30% and acetyl dipeptide-1 cetyl ester 0.10% - 0.45%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 107.64A$ in Australia, for 54.00$ in the United States and for 122.58£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.

  1. 1
    Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
  2. 2
    Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
  3. 3
    Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory propertiesonlinelibrary.wiley.com
  4. 4
    Vitamin E in dermatologyncbi.nlm.nih.gov
  5. 5
    Vitamin E and Skin Healthlpi.oregonstate.edu
  6. 6
    Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oilsmdpi.com
DRMTLGY Advanced Neck Cream
DRMTLGYAdvanced Neck Cream
Buy at drmtlgy≈ $66.11$54.00as of 10/19 12:05 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at drmtlgy≈ $66.11$54.00as of 10/19 12:05 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.