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Peter Thomas Roth Peptide Skinjection Moisture Infusion Refillable Cream
Peter Thomas Roth

Peter Thomas Roth Peptide Skinjection Moisture Infusion Refillable Cream

Efficacy66/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Hexapeptide-11, Acetyl hexapeptide-1 + 36 more
Works well
What the product description says
“PETER THOMAS ROTH CLINICAL SKIN CARE PEPTIDE SKINJECTIONTM Moisture Infusion Cream is a peptide-packed, refillable moisturizer that helps to restore the look of youthful bounce, plumping the look of skin with intense hydration.”
Source: Peter Thomas Roth

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, dextran.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl dipeptide-1 cetyl ester, acetyl hexapeptide-1, acetyl hexapeptide-8, acetyl octapeptide-3, acetyl tetrapeptide-11, acetyl tetrapeptide-2, acetyl tetrapeptide-9, dipeptide diaminobutyroyl benzylamide diacetate, hexapeptide-11, palmitoyl dipeptide-10, palmitoyl hexapeptide-12, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1, tripeptide-10 citrulline

Hexapeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Acetyl hexapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.65%
Palmitoyl dipeptide-10HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Tripeptide-10 citrullineHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%
Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl dipeptide-1 cetyl esterHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl octapeptide-3Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Acetyl tetrapeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-9HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.7–5.7%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~4.2–5.1%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2–2.4%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.75–1.15%
PhytosterolsKey active· EmollientEffect: HighLipids that work as an emollient and can be helpful in repairing skin barrier function~0.3–0.55%
SqualeneKey active· Emollient, OcclusiveEffect: HighAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~0.3–0.5%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.25–0.45%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.25–0.4%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.25–0.45%
MannitolKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin~0.25–0.45%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.25–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.6–1.9%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~1.5–1.8%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~1.2–1.5%
Batyl alcohol· EmollientEffect: LowNon-drying alcohol. Used to stabilize other ingredients and is an emollient~1–1.2%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.3–0.55%
BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.25–0.45%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Simmondsia chinensis seed oilUnder-dosedSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.6–0.9%
Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.3–0.55%
Anti-aging
Hexapeptide-11, Acetyl hexapeptide-1 + 14 more
Works well
What the product description says
“Helps fine lines and wrinkles appear diminished, with an overall decrease in the look of eleven lines, marionette lines and pout lines after just one week.*”
Source: Peter Thomas Roth

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl dipeptide-1 cetyl ester, acetyl hexapeptide-1, acetyl hexapeptide-8, acetyl octapeptide-3, acetyl tetrapeptide-11, acetyl tetrapeptide-2, acetyl tetrapeptide-9, dipeptide diaminobutyroyl benzylamide diacetate, hexapeptide-11, palmitoyl dipeptide-10, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1, tripeptide-10 citrulline.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Hexapeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Acetyl hexapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.65%
Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Tripeptide-10 citrullineKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Palmitoyl dipeptide-10Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.6%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%
Acetyl dipeptide-1 cetyl esterKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl octapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Acetyl tetrapeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Acetyl tetrapeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Evens skin tone
No ingredient credited for this claim
Not delivered
What the product description says
“21 amplified Peptides and Neuropeptides help visibly smooth and reduce the look of expression lines while Gamma Proteins help improve the look of elasticity, radiance, uneven skin tone and texture.”
Source: Peter Thomas Roth

Effective ingredients missing or their concentration is too low

Anti-oxidation
Side benefit · Squalene, Cereus grandiflorus flower extract + 1 more
May help

This product contains antioxidants (cereus grandiflorus flower extract, squalene) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

SqualeneKey activeEffect: MediumAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast~0.3–0.5%
Cereus grandiflorus flower extractKey activeEffect: MediumA cactus extract that can help neutralize free radicals because it contains a chemical compound called betacyanins and flavonolglycosides. Can help make the surface of the skin dryer helping make pores look smaller for a very short period of time. The concentrations usually used in cosmetics are too small to have any effect~0.25–0.45%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%

Can it cause trouble?

Irritancy
15 flagged ingredients
Medium risk
We flagged 15 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.6–0.9%est.
Cereus grandiflorus flower extractA cactus extract that can help neutralize free radicals because it contains a chemical compound called betacyanins and flavonolglycosides. Can help make the surface of the skin dryer helping make pores look smaller for a very short period of time. The concentrations usually used in cosmetics are too small to have any effectMedium~0.25–0.45%est.
PhytosterolsLipids that work as an emollient and can be helpful in repairing skin barrier functionMedium~0.3–0.55%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.45%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.25–0.45%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
Sorbic acidA preservativeMedium~0.25–0.45%est.
Potassium sorbateA preservativeMedium~0.25–0.45%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.3–0.55%est.
Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.25–0.45%est.
Laureth-12Helps water and oil mix togetherMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.2–0.4%est.
Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.3–0.5%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.2–0.4%est.
Acrylates copolymerUsed to stabilize product formulation, help create an even product layer over skin (for example, in sunscreen) and create a thicker product consistencyMedium~0.15–0.3%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
SqualeneAn oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast2/5~0.3–0.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.7–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~4.2–5.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Olive oil decyl esters~3.1–3.7%
Formula
Irritation risk
Low
More about Olive oil decyl esters
Glycereth-26~2.3–2.8%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Squalane~2–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Butylene glycol~1.6–1.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Behenyl alcohol~1.5–1.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Polysilicone-11~1.2–1.5%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Batyl alcohol~1–1.2%
Formula
Irritation risk
Low
Works for
MoisturizingAntibacterial

Non-drying alcohol. Used to stabilize other ingredients and is an emollient

More about Batyl alcohol
Cetyl alcohol~0.75–1.15%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Simmondsia chinensis seed oil~0.6–0.9%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Hexapeptide-11~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-11
Acetyl hexapeptide-1~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-1
Tripeptide-10 citrulline~0.4–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-10 citrulline
Palmitoyl dipeptide-10~0.4–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl dipeptide-10
Palmitoyl hexapeptide-12~0.4–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Acetyl hexapeptide-8~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Palmitoyl tripeptide-1~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Acetyl tetrapeptide-11~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-11
Acetyl tetrapeptide-9~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-9
Acetyl octapeptide-3~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl octapeptide-3
Acetyl tetrapeptide-2~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-2
Palmitoyl tetrapeptide-7~0.3–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Tripeptide-1~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1
Acetyl dipeptide-1 cetyl ester~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester
Dipeptide diaminobutyroyl benzylamide diacetate~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate
Arginine~0.25–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Cereus grandiflorus flower extract~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A cactus extract that can help neutralize free radicals because it contains a chemical compound called betacyanins and flavonolglycosides. Can help make the surface of the skin dryer helping make pores look smaller for a very short period of time. The concentrations usually used in cosmetics are too small to have any effect

More about Cereus grandiflorus flower extract
Squalene~0.3–0.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
MoisturizingAnti-oxidation

An oil that is naturally part of skin sebum that helps to soften its upper layer, reduce water loss and neutralize free radicals. It might be comedogenic. Avoid applying large concentrations (or pure oil) before sun exposure as oxidized squalene can clog pores and lead to skin irritation. Today squalene is mostly derived from vegetable oils or synthetized by yeast

More about Squalene
Phytosterols~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Lipids that work as an emollient and can be helpful in repairing skin barrier function

More about Phytosterols
Trehalose~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Silanetriol trehalose ether~0.25–0.5%
Formula
Irritation risk
Low
More about Silanetriol trehalose ether
Biotin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin
Citric acid~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Lecithin~0.3–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Sodium lactate~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Hydrogenated lecithin~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sorbic acid~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Mannitol~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin

More about Mannitol
Amidinobenzyl benzylsulfonyl d-seryl homophenylalaninamide…
Not recognized
Potassium sorbate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium benzoate~0.25–0.45%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Glyceryl stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Caprylic/capric triglyceride~0.3–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Leuconostoc/radish root ferment filtrate~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Dimethyl isosorbide~0.25–0.45%
Formula
Irritation risk
Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide
Potassium hydrolyzed polygamma-glutamate~0.25–0.45%
Formula
Irritation risk
Low
More about Potassium hydrolyzed polygamma-glutamate
Laureth-12~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Laureth-12
Laureth-3~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing
More about Laureth-3
Dextran~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Tocopherol~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Hydroxyethylcellulose~0.25–0.45%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Disodium phosphate~0.25–0.45%
Formula
Irritation risk
Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate
Sodium polyglutamate~0.2–0.4%
Formula
Irritation risk
Low
More about Sodium polyglutamate
Ethylhexylglycerin~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sodium stearoyl glutamate~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate
Polyglyceryl-10 myristate~0.2–0.4%
Formula
Irritation risk
Low
More about Polyglyceryl-10 myristate
Acrylates/c10-30 alkyl acrylate crosspolymer~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Polysorbate 20~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Carbomer~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Sodium phosphate~0.15–0.25%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Sodium phosphate
Acrylates copolymer~0.15–0.3%
Irritant · medium
Irritation risk
Medium

Used to stabilize product formulation, help create an even product layer over skin (for example, in sunscreen) and create a thicker product consistency

More about Acrylates copolymer
Mica~0.15–0.3%
Formula
Irritation risk
Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica
Stearyl alcohol~0.15–0.25%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Glycerin, Dimethicone, Olive oil decyl esters, Glycereth-26, Squalane, Butylene glycol, Behenyl alcohol, Polysilicone-11, Batyl alcohol, Cetyl alcohol, Simmondsia chinensis seed oil, Hexapeptide-11, Acetyl hexapeptide-1, Tripeptide-10 citrulline, Palmitoyl dipeptide-10, Palmitoyl hexapeptide-12, Acetyl hexapeptide-8, Palmitoyl tripeptide-1, Acetyl tetrapeptide-11, Acetyl tetrapeptide-9, Acetyl octapeptide-3, Acetyl tetrapeptide-2, Palmitoyl tetrapeptide-7, Tripeptide-1, Acetyl dipeptide-1 cetyl ester, Dipeptide diaminobutyroyl benzylamide diacetate, Arginine, Sodium hyaluronate, Cereus grandiflorus flower extract, Squalene, Phytosterols, Trehalose, Silanetriol trehalose ether, Biotin, Citric acid, Lecithin, Sodium lactate, Hydrogenated lecithin, Caprylyl glycol, Sorbic acid, Mannitol, Unknown, Potassium sorbate, Sodium benzoate, Glyceryl stearate, Caprylic/capric triglyceride, Leuconostoc/radish root ferment filtrate, Sodium hydroxide, Dimethyl isosorbide, Potassium hydrolyzed polygamma-glutamate, Laureth-12, Laureth-3, Dextran, Tocopherol, Hydroxyethylcellulose, Disodium phosphate, Sodium polyglutamate, Ethylhexylglycerin, Sodium stearoyl glutamate, Polyglyceryl-10 myristate, Acrylates/c10-30 alkyl acrylate crosspolymer, Polysorbate 20, Carbomer, Sodium phosphate, Acrylates copolymer, Mica, Stearyl alcohol, Phenoxyethanol

Compare prices

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Amazon USPrice as of 11/10 03:00 GMT
$55.00
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Peter Thomas Roth50 ml
CRC 27,100.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Peter Thomas RothPeptide Skinjection Moisture Infusion Refillable CreamYOUR PRODUCTBIOHEAL BOHProbioderm 3D Lifting CreamMEDI-PEELPeptide 9 Volume Tox Cream ProCliniqueSmart Clinical Repair Wrinkle Correcting Cream
Match—44%41%40%
PriceCRC 27,100.00$27.99$26.33$50.74
Shared key ingredients—12 of 3112 of 319 of 31
Key difference—Acetyl Tetrapeptide-5Copper Tripeptide-1Aminopropyl Ascorbyl Phosphate
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Safety Assessment of Glycerin Ethoxylates as Used in Cosmeticscir-safety.org
  5. 5
    Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
  6. 6
    Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
Peter Thomas Roth Peptide Skinjection Moisture Infusion Refillable Cream
Peter Thomas RothPeptide Skinjection Moisture Infusion Refillable Cream
Buy at Peter Thomas RothCRC 27,100.00$55.00as of 11/10 03:00 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Peter Thomas RothCRC 27,100.00$55.00as of 11/10 03:00 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.