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Replenix Lifting and Firming Neck Cream
Replenix

Replenix Lifting and Firming Neck Cream

Efficacy100/100IrritancyHigh
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Works for

3 of 3 advertised claims delivered

Anti-aging
6 ingredients credited for this claim
Strong support
What the product description says
“visibly reducing signs of aging”
Source: Lookfantastic CA

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide, palmitoyl hexapeptide-12.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl pentapeptide-4.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
Palmitoyl hexapeptide-12Key activeEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.25–0.4%
Glucosamine hclEffect: LowMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.45–0.7%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.4%
Moisturizing
28 ingredients credited for this claim
Strong support
What the product description says
“hydrating neck cream”
Source: Lookfantastic CA

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glucosamine hcl, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ap, ceramide eop, ceramide ng, ceramide np, niacinamide, palmitoyl hexapeptide-12, palmitoyl pentapeptide-4, phytosphingosine

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.8%
PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.3–0.6%
Saccharomyces lysate extractKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Can have some anti-inflammatory effect~0.2–0.4%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.8–2.2%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.25–0.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~5.7–7%
Ceramide apHeroEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.4–0.6%
Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.45–0.65%
Ceramide ngHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.35–0.65%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.45–0.7%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.55%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.1–2.6%
Glucosamine hclKey active· HumectantEffect: HighMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.45–0.7%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
Palmitoyl hexapeptide-12HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.3–0.55%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~0.25–0.45%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.25–0.45%
Leontopodium alpinum callus culture extractKey active· HumectantEffect: MediumA plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin~0.95–1.15%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~2.4–2.9%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~2.9–3.5%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.2–0.35%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.35%
Tribehenin· EmollientEffect: LowUsed to create a thicker product consistency and soften the upper layer of the skin~0.25–0.45%
Pyrus malus fruit extractUnder-dosedEffect: MediumCan have some moisturizing properties due to its sugar content~0.2–0.35%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.4%
Evens skin tone
4 ingredients credited for this claim
Strong support
What the product description says
“even skin tone”
Source: Lookfantastic CA

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glucosamine hcl.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
Glucosamine hclKey activeEffect: MediumMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.45–0.7%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.4%
Pisum sativum extractEffect: Low, below effective doseMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking~0.5–0.75%
Anti-oxidation
Not advertised by the brand · 9 ingredients credited for this claim
Strong support

This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.25–0.4%
CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~1.1–1.4%
Leontopodium alpinum callus culture extractEffect: LowA plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin~0.95–1.15%
Vaccinium macrocarpon fruit extractEffect: LowA berry extract. Might have some anti-oxidant properties~0.2–0.4%
Glucosamine hclEffect: LowMight be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.~0.45–0.7%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.4%
Pyrus malus fruit extractEffect: Low, below effective doseCan have some moisturizing properties due to its sugar content~0.2–0.35%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.7–1%
Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.2–0.35%
Anti-blemish
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.3–0.6%
Rosmarinus officinalis leaf extractUnder-dosedEffect: MediumCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.2–0.35%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.4%

Can it cause trouble?

Irritancy
5 strong irritants: Mentha piperita leaf extract, Eucalyptus globulus leaf extract + 3 more — patch-test recommended
High risk
We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Anthemis nobilis flower extractA plant extract that one one hand, can contain compounds that can help calm down skin irritation, but, on the other hand, its other compounds (especially fragrant ones) can themselves be irritatingHigh~0.2–0.35%est.
Mentha piperita leaf extractUsed as a fragrance and can be irritatingHigh~0.2–0.4%est.
Eucalyptus globulus leaf extractUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.
Lavandula angustifolia flower/leaf/stem extractUsed as a fragranceHigh~0.2–0.4%est.
Vaccinium macrocarpon fruit extractA berry extract. Might have some anti-oxidant propertiesHigh~0.2–0.4%est.
Rose extractUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.2–0.35%est.
Mentha viridis extractUsed as a fragrance and can be irritatingHigh~0.25–0.45%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~5.7–7%est.
CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~1.1–1.4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.7–1%est.
Pisum sativum extractMight be helpful in protecting skin collagen and elastin from breaking down but solid research is lackingMedium~0.5–0.75%est.
Sodium lauroyl lactylateHelps water and oil mix togetherMedium~0.25–0.5%est.
Pyrus malus fruit extractCan have some moisturizing properties due to its sugar contentMedium~0.2–0.35%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.2–0.4%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.2–0.4%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.35%est.
Sorbic acidA preservativeMedium~0.15–0.3%est.
Potassium hydroxideUsed to adjust the pH level of productsMedium~0.1–0.25%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.25–0.45%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~5.7–7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Glycerin~4–4.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glyceryl stearate~2.9–3.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
C12-15 alkyl benzoate~2.4–2.9%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Dimethicone~2.1–2.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Squalane~1.8–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Niacinamide~1.4–1.8%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Caffeine~1.1–1.4%
Irritant · medium
Irritation risk
Medium
Works for
De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine
Leontopodium alpinum callus culture extract~0.95–1.15%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plant stem cell extract that might help neutralize free radicals and reduce inflammation in skin

More about Leontopodium alpinum callus culture extract
Tocopheryl acetate~0.7–1%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Bambusa vulgaris extract~0.55–0.8%
Formula
Irritation risk
Low
More about Bambusa vulgaris extract
Pisum sativum extract~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Evens skin tone

Might be helpful in protecting skin collagen and elastin from breaking down but solid research is lacking

More about Pisum sativum extract
Glucosamine hcl~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAntibacterialEvens skin toneAnti-agingAnti-oxidation

Might be able to stimulate production of skin's natural moisturizing compounds such as hyaluronic acid. Could be helpful for evening the skin tone.

More about Glucosamine hcl
Ceramide ap~0.4–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ap
Ceramide np~0.45–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Ceramide eop~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide eop
Ceramide ng~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ng
Phospholipids~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Phytosphingosine~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine
Cholesterol~0.3–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingCleansing

An emollient that is naturally found in skin

More about Cholesterol
Sodium lauroyl lactylate~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Sodium lauroyl lactylate
Camellia sinensis polyphenols~0.2–0.35%
Formula
Irritation risk
Low
More about Camellia sinensis polyphenols
Malus domestica fruit cell culture extract~0.2–0.4%
Formula
Irritation risk
Low
More about Malus domestica fruit cell culture extract
Ubiquinone~0.25–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Anthemis nobilis flower extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Reduces irritationAnti-inflammatory

A plant extract that one one hand, can contain compounds that can help calm down skin irritation, but, on the other hand, its other compounds (especially fragrant ones) can themselves be irritating

More about Anthemis nobilis flower extract
Mentha piperita leaf extract~0.2–0.4%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha piperita leaf extract
Eucalyptus globulus leaf extract~0.2–0.35%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Eucalyptus globulus leaf extract
Lavandula angustifolia flower/leaf/stem extract~0.2–0.4%
Irritant · high
Irritation risk
High

Used as a fragrance

More about Lavandula angustifolia flower/leaf/stem extract
Pyrus malus fruit extract~0.2–0.35%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Camellia sinensis leaf extract~0.25–0.4%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Vaccinium macrocarpon fruit extract~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A berry extract. Might have some anti-oxidant properties

More about Vaccinium macrocarpon fruit extract
Rose extract~0.2–0.35%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating

More about Rose extract
Pogostemon cablin leaf extract~0.2–0.35%
Formula
Irritation risk
Low
More about Pogostemon cablin leaf extract
Rosmarinus officinalis leaf extract~0.2–0.35%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Mentha viridis extract~0.25–0.45%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha viridis extract
Lecithin~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Palmitoyl hexapeptide-12~0.2–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl hexapeptide-12
Saccharomyces lysate extract~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect

More about Saccharomyces lysate extract
Palmitoyl pentapeptide-4~0.2–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4
Tribehenin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a thicker product consistency and soften the upper layer of the skin

More about Tribehenin
Cetyl palmitate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Peg-100 stearate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Peg-10 rapeseed sterol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-10 rapeseed sterol
Cetearyl alcohol~0.25–0.45%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Butylene glycol~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Polysorbate 20~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Polysorbate 60~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Carbomer~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Xanthan gum~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Phenoxyethanol~0.15–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Caprylyl glycol~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sorbic acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Potassium hydroxide~0.1–0.25%
Irritant · medium
Irritation risk
Medium

Used to adjust the pH level of products

More about Potassium hydroxide
Disodium edta~0.1–0.15%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ingredient list view

Water, Caprylic/capric triglyceride, Glycerin, Glyceryl stearate, C12-15 alkyl benzoate, Dimethicone, Squalane, Niacinamide, Caffeine, Leontopodium alpinum callus culture extract, Tocopheryl acetate, Bambusa vulgaris extract, Pisum sativum extract, Glucosamine hcl, Ceramide ap, Ceramide np, Ceramide eop, Ceramide ng, Phospholipids, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Camellia sinensis polyphenols, Malus domestica fruit cell culture extract, Ubiquinone, Anthemis nobilis flower extract, Mentha piperita leaf extract, Eucalyptus globulus leaf extract, Lavandula angustifolia flower/leaf/stem extract, Pyrus malus fruit extract, Camellia sinensis leaf extract, Vaccinium macrocarpon fruit extract, Rose extract, Pogostemon cablin leaf extract, Rosmarinus officinalis leaf extract, Mentha viridis extract, Lecithin, Palmitoyl hexapeptide-12, Saccharomyces lysate extract, Palmitoyl pentapeptide-4, Tribehenin, Cetyl palmitate, Peg-100 stearate, Peg-10 rapeseed sterol, Cetearyl alcohol, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Butylene glycol, Polysorbate 20, Polysorbate 60, Carbomer, Xanthan gum, Phenoxyethanol, Caprylyl glycol, Sorbic acid, Potassium hydroxide, Disodium edta

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Amazon USPrice as of 10/10/2026 00:02 GMT
$99.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ReplenixLifting and Firming Neck CreamYOUR PRODUCTTIRTIRMatcha Calming Cream 50mlSUNGBOON EDITORAlaska Salmon PDRN Ultra Moisturizing Barrier CreamNeocutisBIO Cream Firm
Match—78%76%75%
Price$92.00$43.56−$48.44$21.10−$70.90$178.00+$86.00
Shared key ingredients—12 of 199 of 199 of 19
Key difference—Dipeptide-2AdenosinePalmitoyl Tripeptide-1 Acetate
Irritancy High Medium Medium Medium
Drying alcohol————
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Product summary

"Replenix - Lifting and Firming Neck Cream" is a well-rounded moisturizing product. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (glucosamine hcl, glycerin, saccharomyces lysate extract, leontopodium alpinum callus culture extract and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide eop, ceramide ng, ceramide np, phytosphingosine and cholesterol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (phytosphingosine 0.30% - 0.60%, ceramide np 0.45% - 0.70%, ceramide ng 0.35% - 0.65%, ceramide eop 0.45% - 0.65% and ceramide ap 0.40% - 0.60%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • We like that this moisturizer contains peptides (palmitoyl pentapeptide-4 0.20% - 0.40% and palmitoyl hexapeptide-12 0.20% - 0.40%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 92.00$ up to 96.00$ in the United States, for 480.78A$ in Australia and for 88.40CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 14 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  5. 5
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  6. 6
    Anti-Inflammatory Effects of Concentrated Ethanol Extracts of Edelweiss (Leontopodium alpinum Cass.) Callus Cultures towards Human Keratinocytes and Endothelial Cellshindawi.com
Replenix Lifting and Firming Neck Cream
ReplenixLifting and Firming Neck Cream
Buy on Amazon$99.00 · as of 10/10 00:02 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$99.00 · as of 10/10 00:02 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.