Replenix

Replenix Anti-Photoageing System

Name: Replenix - Anti-Photoageing System
Brand: Replenix

SPF 50Efficacy60/100IrritancyHigh·1 UV filter

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Works for

3 of 4 advertised claims delivered

Sun protection

SPF 50 · 1 UV filter · Broad spectrum

Weak protectionLow zinc dose

SPF 50Broad spectrumMineral filters

This product uses a single UV filter (zinc oxide) in a relatively low concentration and might not be able to provide a reliable sun protection.

This product can be considered "reef safe" because it does not contain the UV filters (oxybenzone and octinoxate) that can be harmful to coral reefs when present in the water in high concentrations.

UV spectrum

UVB290–320 nmUVA II320–340 nmUVA I340–400 nm

Zinc Oxide

FilterCoverageWhat it doesEst. amount

Zinc Oxide Mineral UVBUVA Photo-stable A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant13.75%

Reef-safe

No oxybenzone or octinoxate — the two filters banned in Hawaii, Florida Keys and Aruba.

Anti-oxidation

13 ingredients credited for this claim

Strong support

This product contains antioxidants (glutathione, resveratrol, retinol, ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia sinensis extract, emblica officinalis fruit extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~1.1–1.4%

ResveratrolKey activeEffect: HighHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone~0.25–0.5%

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.25–0.45%

Camellia sinensis extractKey activeEffect: MediumTea extract. Might be helpful in neutralizing free radicals in skin~1.8–2.1%

Emblica officinalis fruit extractKey activeEffect: MediumA plant extract that might be helping in neutralizing free radicals in skin. It could help reduce hyperpigmentation. There is some research to confirm its effectiveness in skin~0.25–0.45%

CaffeineEffect: LowMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes~0.25–0.45%

Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.95–1.15%

Ascorbic acidUnder-dosedEffect: HighThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.4–0.6%

ErgothioneineUnder-dosedEffect: HighCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~1.3–1.6%

BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.25–0.4%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.25–0.5%

Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.4–0.6%

Moisturizing

32 ingredients credited for this claim

Strong support

What the product description says

“Awaken to younger, hydrated, healthier looking skin.”

Source: Lookfantastic US

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: copper pca, cyclomethicone.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, cholesterol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide 2, ceramide ap, ceramide eop, ceramide np, phytosphingosine, tetrapeptide-21

Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.25–0.45%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.3–0.55%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.55%

Tetrapeptide-21HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Zinc pcaKey active· HumectantEffect: HighA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.95–1.15%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%

Peg/ppg-18/18 dimethiconeKey activeEffect: HighA silicone that mixes with water creating nice light-weight product texture~0.3–0.5%

Palmitoyl tripeptide-28Key activeEffect: High~1.5–1.9%

Hydrolyzed sodium hyaluronateKey activeEffect: HighAttracts water into the upper layer of the skin~2.2–2.7%

Ceramide 2Hero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.5%

Ceramide apHeroEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%

Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.5%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.55%

PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.3–0.55%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.55%

Copper pcaKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.65–0.95%

CyclomethiconeKey active· Humectant, EmollientEffect: HighA type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer~0.3–0.5%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.25–0.45%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.3–0.55%

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~0.3–0.55%

Dimethicone crosspolymerKey activeEffect: MediumUsed to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface~0.2–0.35%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.35–0.65%

Cetyl peg/ppg-10/1 dimethiconeEffect: LowA type of silicone that helps water and oil mix together. Can help to soften upper layer of the skin~0.25–0.5%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.3%

C13-14 isoparaffin· EmollientEffect: LowHelps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency~0.3–0.55%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.25–0.5%

Neopentyl glycol diheptanoate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~0.25–0.5%

Caprylic/capric triglycerideUnder-dosedEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.3–0.55%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.5%

Anti-aging

10 ingredients credited for this claim

Strong support

What the product description says

“The appearance of fine lines is minimised.”

Source: Lookfantastic US

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tripeptide-28, resveratrol, tetrapeptide-21.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%

ResveratrolKey activeEffect: MediumHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone~0.25–0.5%

Tetrapeptide-21Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl tripeptide-28Key activeEffect: Medium~1.5–1.9%

UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.25–0.45%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%

Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.2–0.4%

Evens skin tone

Not advertised by the brand · 6 ingredients credited for this claim

Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains glutathione. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: emblica officinalis fruit extract, resveratrol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

This product can also help with skin tone because it offers sun protection. Sun damage is the main factor causing age spots, darkening of post-acne marks and other discolorations. This is why sun protection is the best strategy for maintaining an even skin tone. We, however, do not recommend using this product as a sunscreen because the protection it offers is not strong enough).

ResveratrolEffect: LowHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone~0.25–0.5%

Emblica officinalis fruit extractEffect: LowA plant extract that might be helping in neutralizing free radicals in skin. It could help reduce hyperpigmentation. There is some research to confirm its effectiveness in skin~0.25–0.45%

Exfoliation

Not advertised by the brand · 2 ingredients credited for this claim

Strong support

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

Retinyl palmitateEffect: Low, below effective doseThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.2–0.4%

Anti-blemish

Not advertised by the brand · 4 ingredients credited for this claim

Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: zinc pca

Zinc pcaKey activeEffect: MediumA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.95–1.15%

PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.3–0.55%

Can it cause trouble?

Irritancy

3 strong irritants: Retinyl palmitate, Retinol + 1 more — patch-test recommended

High risk

We flagged 22 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.4–0.6%est.

Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.2–0.4%est.

RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.2–0.4%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.1%est.

GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~1.1–1.4%est.

Disodium edtaStabilizes the product formulationMedium~0.5–0.7%est.

Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.4–0.6%est.

Emblica officinalis fruit extractA plant extract that might be helping in neutralizing free radicals in skin. It could help reduce hyperpigmentation. There is some research to confirm its effectiveness in skinMedium~0.25–0.45%est.

Lauryl peg/ppg-18/18 methiconeHelps oil and water mix together. It might be irritating for some peopleMedium~0.25–0.45%est.

Polyhydroxystearic acidUsed to create a thicker product consistency and stabilize the formulationMedium~0.3–0.5%est.

Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.3–0.5%est.

Potassium hydroxideUsed to adjust the pH level of productsMedium~0.25–0.5%est.

ResveratrolHelps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin toneMedium~0.25–0.5%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.5%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.45%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.3–0.55%est.

Polysorbate 60Helps oil and water mix togetherMedium~0.3–0.5%est.

PolyacrylamideUsed to improve product texture and help oil and water mix togetherMedium~0.3–0.5%est.

Laureth-7Helps oil and water mix togetherMedium~0.25–0.5%est.

Sodium lauroyl lactylateHelps water and oil mix togetherMedium~0.25–0.5%est.

Sorbic acidA preservativeMedium~0.15–0.25%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.3%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.35–0.65%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.3–0.55%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.3–5.2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Sodium pca~3.9–4.8%

Key active

Irritation risk: Low

Works for

Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca

Sodium hyaluronate~3–3.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Hydrolyzed sodium hyaluronate~2.2–2.7%

Key active

Irritation risk: Low

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Hydrolyzed sodium hyaluronate

Camellia sinensis extract~1.8–2.1%

Key active

Irritation risk: Low

Works for

Anti-oxidation

Tea extract. Might be helpful in neutralizing free radicals in skin

More about Camellia sinensis extract

Palmitoyl tripeptide-28~1.5–1.9%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

More about Palmitoyl tripeptide-28

Ergothioneine~1.3–1.6%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine

Glutathione~1.1–1.4%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneAnti-oxidationMoisturizing

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione

Zinc pca~0.95–1.15%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-blemishAnti-oxidationAnti-aging

A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing

More about Zinc pca

Copper pca~0.65–0.95%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Copper pca

Phenoxyethanol~0.55–0.8%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Disodium edta~0.5–0.7%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Zinc oxide13.75%

UV filterKey active

Irritation risk: Low

Works for

Sun protection

A broad spectrum sunblock (protects from both UVA and UVB rays). Is suitable for most sensitive skins. In small concentrations, can be used as a colorant

More about Zinc oxide

Acrylates crosspolymer-4~0.45–0.7%

Formula

Irritation risk: Low

Works for

Cleansing

More about Acrylates crosspolymer-4

Ascorbic acid~0.4–0.6%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingAnti-oxidationEvens skin tone

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Ascorbyl palmitate~0.4–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate

Biotin~0.35–0.65%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Camellia sinensis polyphenols~0.4–0.65%

Formula

Irritation risk: Low

More about Camellia sinensis polyphenols

Cetearyl alcohol~0.35–0.65%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Ceteth-10 phosphate~0.4–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

More about Ceteth-10 phosphate

Cetyl peg/ppg-10/1 dimethicone~0.25–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

A type of silicone that helps water and oil mix together. Can help to soften upper layer of the skin

More about Cetyl peg/ppg-10/1 dimethicone

Cyclopentasiloxane~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Dicetyl phosphate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

More about Dicetyl phosphate

Disodium edta~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Emblica officinalis fruit extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationEvens skin tone

A plant extract that might be helping in neutralizing free radicals in skin. It could help reduce hyperpigmentation. There is some research to confirm its effectiveness in skin

More about Emblica officinalis fruit extract

Glyceryl isostearate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Glyceryl isostearate

Lauryl peg/ppg-18/18 methicone~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps oil and water mix together. It might be irritating for some people

More about Lauryl peg/ppg-18/18 methicone

Neopentyl glycol diheptanoate~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Neopentyl glycol diheptanoate

Phenoxyethanol~0.25–0.5%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Phospholipids~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Polyhydroxystearic acid~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to create a thicker product consistency and stabilize the formulation

More about Polyhydroxystearic acid

Potassium cetyl phosphate~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate

Potassium hydroxide~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Used to adjust the pH level of products

More about Potassium hydroxide

Water~0.25–0.45%

Formula

Irritation risk: Low

Plain old water

More about Water

Retinyl palmitate~0.2–0.4%

Under-dosedIrritant · high

Irritation risk: High

Works for

Anti-agingAnti-blemishEvens skin toneExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate

Resveratrol~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-agingEvens skin tone

Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone

More about Resveratrol

Tocopheryl acetate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Ubiquinone~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone

Xanthan gum~0.25–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Cyclopentasiloxane~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Dimethicone crosspolymer~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface

More about Dimethicone crosspolymer

Cyclomethicone~0.3–0.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of silicone that leaves a nice silky finish on the skin and can help soften its upper layer

More about Cyclomethicone

Peg/ppg-18/18 dimethicone~0.3–0.5%

Key active

Irritation risk: Low

Works for

MoisturizingCleansing

A silicone that mixes with water creating nice light-weight product texture

More about Peg/ppg-18/18 dimethicone

Caffeine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Camellia sinensis polyphenols~0.25–0.45%

Formula

Irritation risk: Low

More about Camellia sinensis polyphenols

Retinol~0.2–0.4%

Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high

Irritation risk: High

Works for

Anti-agingMattifyingExfoliationAnti-blemishEvens skin toneAnti-oxidation

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol

Polysorbate 20~0.3–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Water~0.25–0.45%

Formula

Irritation risk: Low

Plain old water

More about Water

Hyaluronic acid~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Water~0.25–0.45%

Formula

Irritation risk: Low

Plain old water

More about Water

Cyclopentasiloxane~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Sodium pca~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca

Glycerin~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Caprylic/capric triglyceride~0.3–0.55%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Polysorbate 60~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 60

Cetearyl alcohol~0.3–0.55%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Yucca glauca root extract~0.25–0.45%

Formula

Irritation risk: Low

More about Yucca glauca root extract

Dimeth i cone, ceteary l gl u c o s i d e

Not recognized

Polyacrylamide~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Used to improve product texture and help oil and water mix together

More about Polyacrylamide

C13-14 isoparaffin~0.3–0.55%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin

Laureth-7~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Laureth-7

Ceramide np~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Ceramide ap~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces irritationMoisturizingAnti-inflammatory

More about Ceramide ap

Ceramide eop~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces irritationMoisturizingAnti-inflammatory

More about Ceramide eop

Sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Phytosphingosine~0.3–0.55%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine

Cholesterol~0.3–0.55%

Key active

Irritation risk: Low

Works for

MoisturizingCleansing

An emollient that is naturally found in skin

More about Cholesterol

Sodium lauroyl lactylate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Sodium lauroyl lactylate

Camellia sinensis polyphenols~0.25–0.45%

Formula

Irritation risk: Low

More about Camellia sinensis polyphenols

Malus domestica fruit cell culture extract~0.25–0.45%

Formula

Irritation risk: Low

More about Malus domestica fruit cell culture extract

Squalane~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Ceramide 2~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

More about Ceramide 2

Tetrapeptide-21~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tetrapeptide-21

Resveratrol~0.25–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationAnti-agingEvens skin tone

Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone

More about Resveratrol

Bisabolol~0.25–0.4%

Formula

Irritation risk: Low

Works for

Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol

Caffeine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Lecithin~0.25–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Glyceryl stearate~0.25–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Peg-100 stearate~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate

Dimethicone crosspolymer~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface

More about Dimethicone crosspolymer

Carbomer~0.2–0.35%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Xanthan gum~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Phenoxyethanol~0.1–0.2%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Sorbic acid~0.15–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about Sorbic acid

Caprylyl glycol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Disodium edta~0.05%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Parfum~0.05–0.1%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Ingredient list view

Water, Glycerin, Sodium pca, Sodium hyaluronate, Hydrolyzed sodium hyaluronate, Camellia sinensis extract, Palmitoyl tripeptide-28, Ergothioneine, Glutathione, Zinc pca, Copper pca, Phenoxyethanol, Disodium edta, Zinc oxide, Acrylates crosspolymer-4, Ascorbic acid, Ascorbyl palmitate, Biotin, Camellia sinensis polyphenols, Cetearyl alcohol, Ceteth-10 phosphate, Cetyl peg/ppg-10/1 dimethicone, Cyclopentasiloxane, Dicetyl phosphate, Disodium edta, Emblica officinalis fruit extract, Glyceryl isostearate, Lauryl peg/ppg-18/18 methicone, Neopentyl glycol diheptanoate, Phenoxyethanol, Phospholipids, Polyhydroxystearic acid, Potassium cetyl phosphate, Potassium hydroxide, Water, Retinyl palmitate, Resveratrol, Tocopheryl acetate, Ubiquinone, Xanthan gum, Cyclopentasiloxane, Dimethicone crosspolymer, Cyclomethicone, Peg/ppg-18/18 dimethicone, Caffeine, Camellia sinensis polyphenols, Retinol, Polysorbate 20, Water, Hyaluronic acid, Water, Cyclopentasiloxane, Sodium pca, Glycerin, Caprylic/capric triglyceride, Polysorbate 60, Cetearyl alcohol, Yucca glauca root extract, Unknown, Polyacrylamide, C13-14 isoparaffin, Laureth-7, Ceramide np, Ceramide ap, Ceramide eop, Sodium hyaluronate, Phytosphingosine, Cholesterol, Sodium lauroyl lactylate, Camellia sinensis polyphenols, Malus domestica fruit cell culture extract, Squalane, Ceramide 2, Tetrapeptide-21, Resveratrol, Bisabolol, Caffeine, Lecithin, Glyceryl stearate, Peg-100 stearate, Dimethicone crosspolymer, Carbomer, Xanthan gum, Phenoxyethanol, Sorbic acid, Caprylyl glycol, Disodium edta, Parfum

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ReplenixAnti-Photoageing SystemYOUR PRODUCT	CeraVeSkin Renewing Day Cream SPF 30	Rohto Mentholatum50 Megumi Anti-UV Cream SPF 50+ PA++++	ExuvianceAge Reverse Day Repair SPF 30
Match	—	65%	60%	58%
Price	$286.50	$15.22−$271.28	$19.53−$266.97	$21.00−$265.50
Shared key ingredients	—	11 of 31	8 of 31	3 of 31
Key difference	—	Phenyl Trimethicone	Petrolatum	Acetyl Glucosamine
Irritancy	High	Medium	High	Medium
SPF	SPF 50	SPF 30	SPF 50	SPF 30
Drying alcohol	—	Contains drying alcohol	Contains drying alcohol	—
	View product	Shop	Shop	Shop

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Product summary

"Replenix - Anti-Photoageing System" uses a single UV filter (zinc oxide) in a relatively low concentration and might not be able to provide reliable sun protection.

It also works as a moisturizer, so you do not have to use an additional hydrating product. This product prevents early signs of aging by protecting against sun damage (all broad spectrum sunscreens do that).

Sunscreen filters

This product is a mineral sunscreen. It uses zinc oxide for sun protection. Zinc oxide almost never irritates the skin or stings eyes, but it can leave a white cast.

Irritation risk

This sunscreen contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this product to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 286.50$ up to 293.50$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 33 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
3
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
4
A comparison of the relative antioxidant potency of L‐ergothioneine and idebenoneonlinelibrary.wiley.com
5
l-Ergothioneine Protects Skin Cells against UV-Induced Damage—A Preliminary Studymdpi.com
6
Glutathione as a skin whitening agent: Facts, myths, evidence and controversiesijdvl.com
7
Glutathione for skin lightening: a regnant myth or evidence-based verity?ncbi.nlm.nih.gov
8
Glutathione for skin lightening for dermatologists and cosmetologistsijord.com
9
Zinc L-pyrrolidone carboxylate inhibits the UVA-induced production of matrix metalloproteinase-1 by in vitro cultured skin fibroblasts, whereas it enhances their collagen synthesisonlinelibrary.wiley.com
10
Zinc Therapy in Dermatology: A Review hindawi.com
11
A review of inorganic UV filters zinc oxide and titanium dioxideonlinelibrary.wiley.com
12
Risk assessment of zinc oxide, a cosmetic ingredient used as a UV filter of sunscreensncbi.nlm.nih.gov
13
Characterization of the UVA protection provided by avobenzone, zinc oxide, and titanium dioxide in broad-spectrum sunscreen productsncbi.nlm.nih.gov
14
Ultraviolet Protection Properties of Commercial Sunscreens and Sunscreens Containing Zno Nanorodsiopscience.iop.org
15
ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cellsncbi.nlm.nih.gov
16
Emblicamdedge.com
17
Contact Sensitization to Emulsifying Agents: An Underrated Issue?journals.lww.com
18
Skin permeation and antioxidant efficacy of topically applied resveratrollink.springer.com
19
Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? fasebj.org
20
Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skineuropepmc.org
21
Resveratrol as a Multifunctional Topical Hypopigmenting Agentmdpi.com
22
Anti-aging properties of resveratrol: review and report of a potent new antioxidant skin care formulation
23
Resveratrol: A Unique Antioxidant Offering a Multi-Mechanistic Approach for Treating Aging Skinresearchgate.net
24
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
25
Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
26
A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
27
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
28
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
29
Safety Assessment of Isoparaffins as Used in Cosmeticsjournals.sagepub.com
30
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
31
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
32
Topical emulsions containing ceramides: Effects on the skin barrier function and anti‐inflammatory propertiesonlinelibrary.wiley.com
33
α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammationresearchgate.net

ReplenixAnti-Photoageing System

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