Prequel - BARRIER THERAPY SKIN PROTECTANT CREAM

Prequel BARRIER THERAPY SKIN PROTECTANT CREAM

Efficacy100/100

Works for:

based on ingredients and %
  • Moisturizing
  • Anti-aging

Can it cause trouble?

  • Irritation risk: medium
  • Comedogenic risk ingredients: 2

Key actives

Allantoin1.3% - 1.6%Colloidal oatmeal1Tocopherol0.35% - 0.65%
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Price as of May 2, 2026.
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Product Summary

Based on the ingredients included, "Prequel - BARRIER THERAPY SKIN PROTECTANT CREAM" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Prequel - BARRIER THERAPY SKIN PROTECTANT CREAM ticks this box. Humectants in this product (allantoin, glycerin and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Caprooyl phytosphingosine, ceramide eop, ceramide np, ceramide ns and colloidal oatmeal in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • Another benefit is that this moisturizer contain ceramides (caprooyl sphingosine 0.45% - 0.70%, caprooyl phytosphingosine 0.50% - 0.80%, ceramide ns 0.60% - 0.85%, ceramide np 0.60% - 0.90%, ceramide eop 0.60% - 0.90%, ceramide eos 0.60% - 0.90% and ceramide ap 0.65% - 0.95%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • Adenosine 1.10% - 1.40%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • In addition, this moisturizer contains Allantoin (1.30% - 1.60%). Allantoin is helpful in wound-healing and can help restore the skin barrier faster. It might also be able to improve scars, but the evidence is not very strong for this.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: lecithin, vitamin e and colloidal oatmeal

Irritation risk

There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

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