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Perricone MD High Potency Retinol Recovery Overnight Moisturizer | PerriconeMD
Perricone MD

Perricone MD High Potency Retinol Recovery Overnight Moisturizer | PerriconeMD

Efficacy100/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Retinol, Hyaluronic acid + 4 more
Works well
What the product description says
“This rich, ultra-nourishing moisturizer works overnight with three forms of retinol to help support during the skin’s natural recovery and renewal process by promoting a visible reduction in lines and wrinkles.”
Source: Perricone MD

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.35%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%
Retinyl linoleateUnder-dosedAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.~0.25–0.4%
Moisturizing
Ceramide np, Caprylic/capric triglyceride + 27 more
Works well
What the product description says
“Delivers intense hydration to thoroughly replenish and protect the skin’s moisture barrier for a firmer, smoother, more rested complexion.”
Source: Perricone MD

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.5%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~5.7–6.9%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~4.5–5.5%
Shea butter ethyl estersKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~2.5–3%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.7–2.1%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.5–1.8%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.2–1.5%
Hydrogenated vegetable glyceridesKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.7–1%
Aleurites moluccanus seed oilKey activeEffect: HighHelps soften the upper layer of the skin~0.45–0.7%
Hydrogenated vegetable oilKey active· EmollientEffect: MediumAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin~0.45–0.65%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.35–0.6%
Sodium acetylated hyaluronateKey active· HumectantEffect: HighA type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid~0.25–0.45%
PhytosterolsKey active· EmollientEffect: HighLipids that work as an emollient and can be helpful in repairing skin barrier function~0.25–0.45%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.25–0.5%
Hydrogenated jojoba oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin~0.25–0.5%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~0.25–0.5%
Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.2–0.4%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.2–0.35%
Magnesium aspartateKey activeEffect: MediumMight be helpful in restoring skin barrier function and calm down inflammation in skin~0.2–0.4%
Dicaprylyl carbonate· EmollientEffect: LowHelps products spread more easily and works as an emollient to soften skin~2–2.5%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~1–1.2%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.5–0.75%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.3–0.55%
Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~0.3–0.55%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%
PetrolatumUnder-dosedOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.3–0.5%
Zinc gluconateUnder-dosedTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.2–0.4%
Copper gluconateUnder-dosedTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%
Exfoliation
Retinol, Zinc gluconate + 1 more
Works well
What the product description says
“Triple Retinol Blend – for advanced Skin Recovery. This unique blend of encapsulated retinol, retinol ester, and phyto-retinol helps to deliver the appearance of collagen-rich skin, visibly reducing fine lines and wrinkles by accelerating exfoliation of surface skin and renewal.”
Source: Face the future

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.2–0.4%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%
Anti-oxidation
Side benefit · Retinol, Zinc gluconate + 4 more
Works well

This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.2–0.4%
Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.2–0.35%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%
Retinyl linoleateUnder-dosedAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.~0.25–0.4%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.3%
Anti-blemish
Side benefit · Retinol, Zinc gluconate + 3 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.2–0.4%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%
Retinyl linoleateUnder-dosedAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.~0.25–0.4%
Rosmarinus officinalis leaf extractUnder-dosedCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.2–0.35%
Evens skin tone
Side benefit · Retinol, Zinc gluconate + 2 more
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.2–0.4%
Zinc gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin~0.2–0.4%
Copper gluconateEffect: Low, below effective doseTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing~0.15–0.25%
Retinyl linoleateUnder-dosedAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.~0.25–0.4%

Can it cause trouble?

Irritancy
7 strong irritants: Retinol, Parfum + 5 more — patch-test recommended
High risk
We flagged 21 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.2–0.4%est.
Retinyl linoleateAn ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.High~0.25–0.4%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.4%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.2–0.35%est.
CitronellolA fragrance. Can be irritatingHigh~0.15–0.25%est.
GeraniolA fragrance. Can be irritatingHigh~0.1–0.2%est.
HydroxycitronellalA fragrance. A likely allergen and can be irritatingHigh~0.05–0.15%est.
EugenolA fragrance. Is a likely irritantHigh~0.05–0.1%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~5.7–6.9%est.
Isoamyl laurateHelps stabilize emulsions and create a nice product textureMedium~0.55–0.85%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.45–0.7%est.
Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.3–0.55%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.25–0.45%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.3–0.55%est.
Laureth-23Helps oil and water mix togetherMedium~0.3–0.6%est.
Trideceth-6 phosphateHelps oil and water mix togetherMedium~0.25–0.45%est.
Zinc gluconateTypically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skinMedium~0.2–0.4%est.
Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.2–0.4%est.
PhytosterolsLipids that work as an emollient and can be helpful in repairing skin barrier functionMedium~0.25–0.45%est.
Copper gluconateTypically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missingMedium~0.15–0.25%est.
Comedogenic
5 ingredients rated 2 or more on the 0–5 pore-clogging scale
5 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.7–2.1%est.
Hydrogenated vegetable oilAn oil from a mixture of different vegetables. Helps soften the upper layer of the skin2/5~0.45–0.65%est.
Hydrogenated soybean oil—2/5~0.4–0.6%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.45–0.7%est.
Laureth-23Helps oil and water mix together2/5~0.3–0.6%est.
Alternatives
Cheaper, or higher on efficacy
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~5.7–6.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
C12-15 alkyl benzoate~4.5–5.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Propanediol~3.2–3.9%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Shea butter ethyl esters~2.5–3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Shea butter ethyl esters
Dicaprylyl carbonate~2–2.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps products spread more easily and works as an emollient to soften skin

More about Dicaprylyl carbonate
Cetearyl alcohol~1.7–2.1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Dimethicone~1.5–1.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Squalane~1.2–1.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Behenyl alcohol~1–1.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Hydrogenated vegetable glycerides~0.7–1%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

Help soften the upper layer of the skin

More about Hydrogenated vegetable glycerides
Isoamyl laurate~0.55–0.85%
Irritant · medium
Irritation risk
Medium

Helps stabilize emulsions and create a nice product texture

More about Isoamyl laurate
Aleurites moluccanus seed oil~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Aleurites moluccanus seed oil
Glyceryl stearate~0.5–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~0.5–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Hydrogenated vegetable oil~0.45–0.65%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Hydrogenated vegetable oil
Hydrogenated soybean oil~0.4–0.6%
Comedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
More about Hydrogenated soybean oil
Ceteareth-20~0.45–0.7%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Glycerin~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Phenoxyethanol~0.3–0.55%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polysilicone-11~0.3–0.55%
Formula
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11
Sodium stearoyl glutamate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate
Hydrogenated olive oil~0.25–0.45%
Formula
Irritation risk
Low
More about Hydrogenated olive oil
Citric acid~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Dimethyl mea~0.25–0.45%
Formula
Irritation risk
Low
More about Dimethyl mea
Petrolatum~0.3–0.5%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Hydrogenated jojoba oil~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Hydrogenated jojoba oil
Ethylhexylglycerin~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Retinol~0.2–0.4%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Retinyl linoleate~0.25–0.4%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-agingEvens skin toneAnti-blemish

An ester of a retinoid and linoleic acid. Three steps removed from the bioactive form of retinoid, retinoic acid. Once converted to retinoic acid in skin, it can help reduce wrinkles, stimulate collagen production, even out skin tone and reduce blemishes. The concentrations used in cosmetic products are often not high enough to have a positive effect in skin.

More about Retinyl linoleate
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Parfum~0.2–0.4%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Tetrasodium glutamate diacetate~0.25–0.45%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Helianthus annuus seed oil~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Glycine soja lipids~0.25–0.45%
Formula
Irritation risk
Low
More about Glycine soja lipids
Maltodextrin~0.25–0.45%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Pentylene glycol~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Cetyl palmitate~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Laureth-23~0.3–0.6%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together

More about Laureth-23
Disodium acetyl glucosamine phosphate~0.25–0.45%
Formula
Irritation risk
Low
More about Disodium acetyl glucosamine phosphate
Sodium glucuronate~0.25–0.4%
Formula
Irritation risk
Low
More about Sodium glucuronate
Nephelium lappaceum leaf extract~0.2–0.4%
Formula
Irritation risk
Low
More about Nephelium lappaceum leaf extract
Sodium acetylated hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of hyaluronic acid that works as an excellent moisturizer by attracting water into the upper layer of the skin. Is typically feels less sticky on the skin compared to the usual hyaluronic acid

More about Sodium acetylated hyaluronate
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Ceramide np~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Sodium hydroxide~0.25–0.45%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Trideceth-6 phosphate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Trideceth-6 phosphate
Magnesium aspartate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizing

Might be helpful in restoring skin barrier function and calm down inflammation in skin

More about Magnesium aspartate
Zinc gluconate~0.2–0.4%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-agingEvens skin toneAnti-inflammatoryExfoliationAnti-blemishAnti-oxidation

Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin

More about Zinc gluconate
Rosmarinus officinalis leaf extract~0.2–0.35%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Magnesium sulfate~0.25–0.45%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Magnesium sulfate
Sodium hyaluronate crosspolymer~0.2–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer
Hyaluronic acid~0.2–0.35%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Phytosterols~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Lipids that work as an emollient and can be helpful in repairing skin barrier function

More about Phytosterols
Tocopherol~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Copper gluconate~0.15–0.25%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-agingEvens skin toneAnti-blemishExfoliationAnti-oxidation

Typically used to stabilize the product formulations. It is a salt of polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing

More about Copper gluconate
Citronellol~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Geraniol~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Hydroxycitronellal~0.05–0.15%
Irritant · high
Irritation risk
High

A fragrance. A likely allergen and can be irritating

More about Hydroxycitronellal
Eugenol~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Is a likely irritant

More about Eugenol
Ingredient list view

Water, Caprylic/capric triglyceride, C12-15 alkyl benzoate, Propanediol, Shea butter ethyl esters, Dicaprylyl carbonate, Cetearyl alcohol, Dimethicone, Squalane, Behenyl alcohol, Hydrogenated vegetable glycerides, Isoamyl laurate, Aleurites moluccanus seed oil, Glyceryl stearate, Peg-100 stearate, Hydrogenated vegetable oil, Hydrogenated soybean oil, Ceteareth-20, Glycerin, Phenoxyethanol, Polysilicone-11, Sodium stearoyl glutamate, Hydrogenated olive oil, Citric acid, Dimethyl mea, Petrolatum, Hydrogenated jojoba oil, Ethylhexylglycerin, Retinol, Retinyl linoleate, Xanthan gum, Polysorbate 20, Parfum, Tetrasodium glutamate diacetate, Helianthus annuus seed oil, Glycine soja lipids, Maltodextrin, Pentylene glycol, Cetyl palmitate, Laureth-23, Disodium acetyl glucosamine phosphate, Sodium glucuronate, Nephelium lappaceum leaf extract, Sodium acetylated hyaluronate, Sodium hyaluronate, Ceramide np, Sodium hydroxide, Trideceth-6 phosphate, Magnesium aspartate, Zinc gluconate, Rosmarinus officinalis leaf extract, Magnesium sulfate, Sodium hyaluronate crosspolymer, Hyaluronic acid, Phytosterols, Tocopherol, Copper gluconate, Citronellol, Geraniol, Hydroxycitronellal, Eugenol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Perricone MDHigh Potency Retinol Recovery Overnight Moisturizer | PerriconeMDYOUR PRODUCTElizabeth GrantWonder Effect Retinol Ceramide Renewal Day CreamSkinMedicaEven & Correct Dark Spot CreamBlue Lagoon Skin ScienceBL+ The Retinol Cream
Match—79%76%76%
Price$99.00$29.00−$70.00$88.00−$11.00$160.00+$61.00
Shared key ingredients—6 of 216 of 216 of 21
Key difference—Retinyl PalmitateNiacinamideEctoin
Irritancy High Medium Medium Medium
Drying alcohol————
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More alternatives: Blue Lagoon Skincare BL+ Retinol Cream 0.3%Beauty of Joseon Revive Firming Moisturizer

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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 33 studies and safety reviews.

  1. 1
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  2. 2
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  3. 3
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  4. 4
    Retinoids in the treatment of skin aging: an overview of clinical efficacy and safetyncbi.nlm.nih.gov
  5. 5
    Improvement of naturally aged skin with vitamin A (retinol)ncbi.nlm.nih.gov
  6. 6
    A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skinonlinelibrary.wiley.com
Perricone MD High Potency Retinol Recovery Overnight Moisturizer | PerriconeMD
Perricone MDHigh Potency Retinol Recovery Overnight Moisturizer | PerriconeMD
Buy at Perricone MDCheck price$99.00as of 11/10 21:10 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Perricone MDCheck price$99.00as of 11/10 21:10 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.