Dupes & alternatives for Perricone MD-Essential Fx Acyl-Glutathione: Deep Crease Serum

Essential Fx Acyl-Glutathione: Deep Crease Serum
Perricone MD

Essential Fx Acyl-Glutathione: Deep Crease Serum

High irritancy Score: 58/100
20 alternatives found · Best match: 50% (Medium)
Youth Got This Serum
50%
Medium match
$24.00
Medium irritancy

Why it matches

ANHYDROXYLITOLPALMITOYL TRIPEPTIDE-5ACETYL HEXAPEPTIDE-8 +5 more

Key differences

RETINOLGLUTAMIC ACIDGLYCINE +10 more
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Baobab Soothing Moisture Serum
46%
Medium match
$28.00
Medium irritancy

Why it matches

ANHYDROXYLITOLACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5 +2 more

Key differences

COPPER TRIPEPTIDE-1GLUCONOLACTONECERAMIDE EOP +24 more
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Rapidly Renew Daily Serum
43%
Medium match
$19.50
Medium irritancy

Why it matches

PALMITOYL TRIPEPTIDE-5PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINESODIUM HYALURONATE +3 more

Key differences

PALMITOYL TETRAPEPTIDE-7PALMITOYL TRIPEPTIDE-1METHYL METHACRYLATE CROSSPOLYMER +5 more
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IMAGE MD restoring youth repair serum
42%
Medium match
$65.20
High irritancy

Why it matches

TETRAHEXYLDECYL ASCORBATEACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5 +5 more

Key differences

GLYCOLIC ACIDDIPEPTIDE DIAMINOBUTYROYL BENZYLAMIDE DIACETATELINOLEIC ACID +18 more
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Firm X Collagen Serum
Peter Thomas Roth
Firm X Collagen Serum
42%
Medium match
$51.95
Medium irritancy

Why it matches

PALMITOYL DIPEPTIDE-5 DIAMINOBUTYROYL HYDROXYTHREONINEPALMITOYL TRIPEPTIDE-5DIMETHICONE +4 more

Key differences

ACETYL TETRAPEPTIDE-2HYDROLYZED COLLAGENHYDROXYPROLINE +4 more
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själ Bio-Regeneratif Serum Active Energy Lift
$165.00
Medium irritancy

Why it matches

ACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5SQUALANE +2 more

Key differences

ACETYL TETRAPEPTIDE-5GLYCOLIC ACIDPALMITOYL TETRAPEPTIDE-7 +13 more
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Overnight Retinol Repair Serum
41%
Medium match
$75.00
High irritancy

Why it matches

ANHYDROXYLITOLPALMITOYL TRIPEPTIDE-5GLYCERIN +5 more

Key differences

RETINOLSODIUM ASCORBYL PHOSPHATECERAMIDE 3 +4 more
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Strengthen and Rebuild Vegan Serum Concentrate
$92.00
Medium irritancy

Why it matches

ANHYDROXYLITOLPALMITOYL TRIPEPTIDE-5SODIUM HYALURONATE +2 more

Key differences

GLYCOSPHINGOLIPIDSPULLULANSIMMONDSIA CHINENSIS SEED OIL
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Similarity breakdown
Overall formula41%
Hero ingredients67%
Active ingredients39%
All ingredients30%
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Luzern WE3 Triple Action Serum Wrinkle Corrector
41%
Medium match
$170.00
Low irritancy

Why it matches

PALMITOYL TRIPEPTIDE-5ACETYL HEXAPEPTIDE-8SODIUM HYALURONATE +1 more

Key differences

NIACINAMIDEACETYL OCTAPEPTIDE-3PANTHENOL +3 more
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Similarity breakdown
Overall formula41%
Hero ingredients67%
Active ingredients32%
All ingredients18%
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Moisturizing Active Serum
41%
Medium match
$32.42
Medium irritancy

Why it matches

ANHYDROXYLITOLGLYCERINSODIUM HYALURONATE +2 more

Key differences

SACCHARIDE ISOMERATESIMMONDSIA CHINENSIS SEED OIL
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Similarity breakdown
Overall formula41%
Hero ingredients33%
Active ingredients39%
All ingredients25%
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Bakuchiol Miracle Firming Ampoule
40%
Medium match
$22.20
High irritancy

Why it matches

ANHYDROXYLITOLACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5 +4 more

Key differences

COPPER TRIPEPTIDE-1MADECASSOSIDENIACINAMIDE +21 more
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Power Cocktail Lactic Acid Repair Serum
40%
Medium match
$36.90
Medium irritancy

Why it matches

LACTIC ACIDACETYL HEXAPEPTIDE-8SODIUM HYALURONATE +2 more

Key differences

COPPER TRIPEPTIDE-1OLIGOPEPTIDE-1ADENOSINE +11 more
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Anti-Aging Collagen Serum
40%
Medium match
Low irritancy

Why it matches

PALMITOYL TRIPEPTIDE-5ACETYL HEXAPEPTIDE-8CAPRYLIC/CAPRIC TRIGLYCERIDE +3 more

Key differences

HYDROLYZED JOJOBA ESTERSSOLUBLE COLLAGENCAMELLIA SINENSIS LEAF
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Similarity breakdown
Overall formula40%
Hero ingredients67%
Active ingredients39%
All ingredients20%
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Platinum Pep8 Stem Cell Serum
40%
Medium match
$185.00
Medium irritancy

Why it matches

ACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5SODIUM HYALURONATE +1 more

Key differences

N-PROLYL PALMITOYL TRIPEPTIDE-56 ACETATEDIPEPTIDE-2ACETYL OCTAPEPTIDE-3 +18 more
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TRIPLE ACTION PEPTIDE SERUM
40%
Medium match
$90.00
Low irritancy

Why it matches

ACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5GLYCERIN

Key differences

PALMITOYL TETRAPEPTIDE-7PALMITOYL TRIPEPTIDE-1CHRYSIN +1 more
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Similarity breakdown
Overall formula40%
Hero ingredients67%
Active ingredients24%
All ingredients20%
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Superfood Firm and Brighten Vitamin C Serum
39%
Low match
Medium irritancy

Why it matches

LACTIC ACIDPALMITOYL TRIPEPTIDE-5GLYCERIN +1 more

Key differences

PANTHENOLSODIUM HYALURONATE CROSSPOLYMERSUPEROXIDE DISMUTASE +2 more
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Similarity breakdown
Overall formula39%
Hero ingredients67%
Active ingredients32%
All ingredients23%
View full product details
Collagen 100
39%
Low match
$11.96
Low irritancy

Why it matches

PALMITOYL TRIPEPTIDE-5ACETYL HEXAPEPTIDE-8SODIUM HYALURONATE +1 more

Key differences

COPPER TRIPEPTIDE-1ADENOSINEPANTHENOL +5 more
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Calming Moisture Serum
39%
Low match
$12.99
Medium irritancy

Why it matches

PALMITOYL TRIPEPTIDE-5ACETYL HEXAPEPTIDE-8CAPRYLIC/CAPRIC TRIGLYCERIDE +2 more

Key differences

MADECASSOSIDEGLUCONOLACTONEMADECASSIC ACID +14 more
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PeptiDerm Firming Serum
39%
Low match
$174.00
Low irritancy

Why it matches

ACETYL HEXAPEPTIDE-8PALMITOYL TRIPEPTIDE-5GLYCERIN

Key differences

DIPEPTIDE-2ACETYL OCTAPEPTIDE-3PENTAPEPTIDE-18 +6 more
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About Similarity Scores

Our similarity score compares product formulas based on shared active ingredients, hero ingredients, and overall formula composition. A higher score means a more similar formula.

70%+ - High match
40-69% - Medium match
<40% - Low match

Note: Similarity is based on WIMJ's formula analysis (actives + overall formula similarity). Ingredient concentrations are estimated; products aren't lab-tested. A similar formula doesn't guarantee the same texture or feel.